First evidence for an association between joint hypermobility and excitability in a non-human species, the domestic dog
Open accessAbstract
There is a well-established relationship between joint hypermobility and anxiety in humans, that has not previously been investigated in other species. A population of 5575 assistance dogs were scored for both hip hypermobility and 13 behaviour characteristics using previously validated methods. Our results suggest a positive association between hip joint hypermobility and emotional arousal in domestic dogs, which parallel results found in people.
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An animal model provides cross-species evidence of the association between hypermobility and core features of ADHD.
“Interestingly, an animal model provides cross-species evidence of the association between hypermobility and core features of ADHD (49).”
From Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain (2022) · cites this paper as [49]
The Introduction (page not provided) reports an association between hip joint hypermobility and excitability in assistance dogs, which the authors present as cross-species evidence about emotional arousal. It does not identify the measured behaviour as a core feature of ADHD or establish an association with ADHD-specific features. (LLM, conf=0.85)
Experimental — accuracy not yet measuredIn adults, the link between variant connective tissue structure (indexed by joint hypermobility) and affective psychopathology is largely established and reinforced by convergent evidence from domestic dogs.
“In adults, the link between variant connective tissue structure (indexed by joint hypermobility) and affective psychopathology is largely established13 and, interestingly, reinforced by convergent evidence from domestic dogs.41”
From Variant connective tissue (joint hypermobility) and its relevance to depression and anxiety in adolescents: a cohort-based case–control study (2022) · cites this paper as [41]
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- Authors
- Bowen, J., Fatjó, J., Serpell, J. A., Bulbena-Cabré, A., Leighton, E., & Bulbena, A.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- University of Pennsylvania (US)
- Corresponding author
- Fatjó, Jaume
- Venue
- Scientific Reports
- Published
- 2019-06-13
- Volume
- 9
- Issue
- 1
- Pages
- 8629-8629
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC6565730
- OpenAlex
- W2950757748
- Cited by
- 17
- References
- 22
- Citations by year
- 2024: 1 · 2023: 5 · 2022: 4 · 2021: 2 · 2020: 5
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona) (submittedVersion, cc-by)
- RVC Research Online (Royal Veterinary College) (submittedVersion, cc-by)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- RECERCAT (Consorci de Serveis Universitaris de Catalunya) (submittedVersion, other-oa)
- Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion, cc-by)
- Funders
- University of Pennsylvania
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Human-Animal Interaction Studies
- Health Sciences › Veterinary › Small Animals › Animal Behavior and Welfare Studies
- Health Sciences › Veterinary › Small Animals › Veterinary Orthopedics and Neurology
- Keywords
- joint hypermobility, emotional arousal, anxiety, service dogs, dogs, dog behavior, animal models of anxiety, excitability
- MeSH terms
- Animals, Dogs, Humans, Joint Instability, Logistic Models
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