Vitamin C–squalene bioconjugate promotes epidermal thickening and collagen production in human skin

A new mathematical model for relative quantification in real-time RT-PCR

Pfaffl, M. W. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.9.e45 · Cited by 34,610 · see citing works

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., & Speleman, F. (2002) · Genome Biology · doi:10.1186/gb-2002-3-7-research0034 · Cited by 20,038 · see citing works

Causal analysis approaches in Ingenuity Pathway Analysis

Krämer, A., Green, J., Pollard, J., & Tugendreich, S. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btt703 · Cited by 5,724 · see citing works

Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility

Danielson, K. G., Baribault, H., Holmes, D. F., Graham, H. K., Kadler, K. E., & Iozzo, R. V. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.3.729 · Cited by 1,407 · see citing works

The Roles of Vitamin C in Skin Health.

Pullar, J., Carr, A., & Vissers, M. (2017) · Nutrients · doi:10.3390/nu9080866 · Cited by 756 · see citing works

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

Liu, X., Wu, H., Byrne, M., Krane, S., & Jaenisch, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.5.1852 · Cited by 614 · see citing works

Basic Components of Connective Tissues and Extracellular Matrix: Elastin, Fibrillin, Fibulins, Fibrinogen, Fibronectin, Laminin, Tenascins and Thrombospondins

Halper, J., & Kjaer, M. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-94-007-7893-1_3 · Cited by 532 · see citing works

Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage

DARR, D., COMBS, S., DUNSTON, S., MANNING, T., & PINNELL, S. (1992) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1992.tb00122.x · Cited by 337 · see citing works

Hyaluronan in skin: aspects of aging and its pharmacologic modulation

Stern, R., & Maibach, H. I. (2008) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2007.09.013 · Cited by 254 · see citing works

Glycosaminoglycan and proteoglycan in skin aging

Lee, D. H., Oh, J., & Chung, J. H. (2016) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2016.05.016 · Cited by 236 · see citing works

Topical L-Ascorbic Acid: Percutaneous Absorption Studies

Pinnell, S. R., Yang, H., Omar, M., Riviere, N. M., DeBuys, H. V., Walker, L. C., Wang, Y., & Levine, M. (2001) · Dermatologic Surgery · doi:10.1046/j.1524-4725.2001.00264.x · Cited by 213 · see citing works

Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem–Like Cells with Macrophages and Stromal Cells

Okuda, H., Kobayashi, A., Xia, B., Watabe, M., Pai, S. K., Hirota, S., Xing, F., Liu, W., Pandey, P. R., Fukuda, K., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1678 · Cited by 198 · see citing works

Biosynthesis of the Linkage Region of Glycosaminoglycans

Bai, X., Zhou, D., Brown, J. R., Crawford, B. E., Hennet, T., & Esko, J. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107339200 · Cited by 190 · see citing works

Stability of vitamin C derivatives in solution and topical formulations

Austria, R., Semenzato, A., & Bettero, A. (1997) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/s0731-7085(96)01904-8 · Cited by 188 · see citing works

Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications.

(2017) · PubMed Central · Cited by 185 · see citing works

Lasers and microdermabrasion enhance and control topical delivery of vitamin C

Lee, W.-R., Shen, S.-C., Wang, K.-H., Hu, C.-H., & Fang, J.-Y. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12537.x · Cited by 174 · see citing works

Vitamin C regulates keratinocyte viability, epidermal barrier, and basement membrane in vitro, and reduces wound contraction after grafting of cultured skin substitutes

Boyce, S. T., Supp, A. P., Swope, V. B., & Warden, G. D. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01717.x · Cited by 172 · see citing works

Use of Topical Ascorbic Acid and Its Effects on Photodamaged Skin Topography

Traikovich, S. S. (1999) · Archives of Otolaryngology–Head & Neck Surgery · doi:10.1001/archotol.125.10.1091 · Cited by 166 · see citing works

qPrimerDepot: a primer database for quantitative real time PCR

Cui, W., Taub, D. D., & Gardner, K. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl767 · Cited by 158 · see citing works

Role of Vitamin C in Skin Diseases

Wang, K., Jiang, H., Li, W., Qiang, M., Dong, T., & Li, H. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00819 · Cited by 158 · see citing works

NORMA-Gene: A simple and robust method for qPCR normalization based on target gene data

Heckmann, L., Sørensen, P. B., Krogh, P. H., & Sørensen, J. G. (2011) · BMC Bioinformatics · doi:10.1186/1471-2105-12-250 · Cited by 151 · see citing works

Ascorbic Acid in Skin Health

Ravetti, S., Clemente, C. M., Brignone, S. G., Hergert, L. Y., Allemandi, D. A., & Palma, S. D. (2019) · Cosmetics · doi:10.3390/cosmetics6040058 · Cited by 150 · see citing works

A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: Cellular and molecular perspectives of skin ageing

Callaghan, T. M., & Wilhelm, K. ‐. (2008) · International Journal of Cosmetic Science · doi:10.1111/j.1468-2494.2008.00454.x · Cited by 149 · see citing works

Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

Maione-Silva, L., de Castro, E. G., Nascimento, T. L., Cintra, E. R., Moreira, L. C., Cintra, B. A. S., Valadares, M. C., & Lima, E. M. (2019) · Scientific Reports · doi:10.1038/s41598-018-36682-9 · Cited by 148 · see citing works

Squalenoylation: A generic platform for nanoparticular drug delivery

Desmaële, D., Gref, R., & Couvreur, P. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.038 · Cited by 144 · see citing works

Biosynthesis of Dermatan Sulfate

Maccarana, M., Olander, B., Malmström, J. A., Tiedemann, K., Aebersold, R. H., Lindahl, U., Li, J., & Malmström, A. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513373200 · Cited by 142 · see citing works

l-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor

Botzki, A., Rigden, D. J., Braun, S. A., Nukui, M., Salmen, S., Hoechstetter, J., Bernhardt, G., Dove, S., Jedrzejas, M. J., & Buschauer, A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406146200 · Cited by 140 · see citing works

The selective oxidation of the terminal double bonds in squalene

Tamelen, E. E. V., & Curphey, T. J. (1962) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)71112-9 · Cited by 136 · see citing works

Self-Assembled Squalenoylated Penicillin Bioconjugates: An Original Approach for the Treatment of Intracellular Infections

Sémiramoth, N., Meo, C. D., Zouhiri, F., Saïd-Hassane, F., Valetti, S., Gorges, R., Nicolas, V., Poupaert, J. H., Chollet-Martin, S., Desmaële, D., et al. (2012) · ACS Nano · doi:10.1021/nn204928v · Cited by 133 · see citing works

Proteoglycans in Normal and Healing Skin

Smith, M. M., & Melrose, J. (2013) · Advances in Wound Care · doi:10.1089/wound.2013.0464 · Cited by 128 · see citing works

Severe Osteogenesis Imperfecta in Cyclophilin B–Deficient Mice

Choi, J.-W., Sutor, S., Lindquist, L. D., Evans, G. L., Madden, B., Bergen, H. R., Hefferan, T., Yaszemski, M., & Bram, R. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000750 · Cited by 103 · see citing works

Electroporation-mediated topical delivery of vitamin C for cosmetic applications

Zhang, L., Lerner, S., Rustrum, W. V., & Hofmann, G. A. (1999) · Bioelectrochemistry and Bioenergetics · doi:10.1016/s0302-4598(99)00026-4 · Cited by 76 · see citing works

A new protocol for extraction of C0t-1 DNA from rice

Yan, C., Guan, L., Hong, L., Li, G., & Qin, R. (2010) · doi:10.5897/ajb10.1999 · Cited by 70 · see citing works

Mixtures of Stearoyl-6- O -ascorbic Acid and α-Tocopherol: A Monolayer Study at the Gas/Water Interface

Capuzzi, G., Nostro, P. L., Kulkarni, K., & Fernandez, J. E. (1996) · Langmuir · doi:10.1021/la960001y · Cited by 68 · see citing works

Skin atrophy in cytoplasmic SOD-deficient mice and its complete recovery using a vitamin C derivative

Murakami, K., Inagaki, J., Saito, M., Ikeda, Y., Tsuda, C., Noda, Y., Kawakami, S., Shirasawa, T., & Shimizu, T. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.03.053 · Cited by 64 · see citing works

Topical delivery of retinyl ascorbate co-drug

Abdulmajed, K., & Heard, C. M. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2004.05.008 · Cited by 56 · see citing works

Collagen XVI Harbors an Integrin α1β1 Recognition Site in Its C-terminal Domains

Eble, J. A., Kassner, A., Niland, S., Mörgelin, M., Grifka, J. K., & Grässel, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m509942200 · Cited by 53 · see citing works

Inhibitory effects of a novel ascorbic derivative, disodium isostearyl 2-O-l-ascorbyl phosphate on melanogenesis

Matsuda, S., Shibayama, H., Hisama, M., Ohtsuki, M., & Iwaki, M. (2008) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.56.292 · Cited by 51 · see citing works

Estimation of Sebum Production Rates in Man by Measurement of the Squalene Content of Skin Biopsies

Downing, D. T., Stewart, M. E., & Strauss, J. S. (1981) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12493260 · Cited by 43 · see citing works

Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases

Spickenreither, M., Braun, S. A., Bernhardt, G., Dove, S., & Buschauer, A. (2006) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2006.07.087 · Cited by 41 · see citing works

Synthesis of ascorbyloleate by immobilized Candida antarctica lipases

Adamczak, M., Bornscheuer, U. T., & Bednarski, W. (2005) · Process Biochemistry · doi:10.1016/j.procbio.2005.01.016 · Cited by 32 · see citing works

Novel self assembling nanoparticles for the oral administration of fondaparinux: Synthesis, characterization and in vivo evaluation

Ralay-Ranaivo, B., Desmaële, D., Bianchini, E. P., Lepeltier, É., Bourgaux, C., Borgel, D., Pouget, T., Tranchant, J., Couvreur, P., & Gref, R. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.07.060 · Cited by 32 · see citing works

Lipase‐catalyzed synthesis of unsaturated acyl l‐ascorbates and their ability to suppress the autoxidation of polyunsaturated fatty acids

Watanabe, Y., Adachi, S., Nakanishi, K., & Matsuno, R. (2001) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-001-0349-1 · Cited by 31 · see citing works

Type III Collagen

Nielsen, M. J., & Karsdal, M. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-809847-9.00003-9 · Cited by 31 · see citing works

Characterization of Skin Permeation of Vitamin C: Theoretical Analysis of Penetration Profiles and Differential Scanning Calorimetry Study.

Lee, A.-R. C., & Tojo, K. J. (1998) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.46.174 · Cited by 30 · see citing works

Adiponectin promotes hyaluronan synthesis along with increases in hyaluronan synthase 2 transcripts through an AMP-activated protein kinase/peroxisome proliferator-activated receptor-α-dependent pathway in human dermal fibroblasts

Yamane, T., Kobayashi, K., & Oishi, Y. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.09.151 · Cited by 29 · see citing works

[Quantification of type I and III collagen content in normal human skin in different age groups].

Rong, Y., Zhang, G.-A., Wang, C., & Ning, F. (2008) · PubMed · Cited by 20 · see citing works

Topical Application of Trisodium Ascorbyl 6-Palmitate 2-Phosphate Actively Supplies Ascorbate to Skin Cells in an Ascorbate Transporter-Independent Manner

Shibuya, S., Sakaguchi, I., Ito, S., Kato, E., Watanabe, K., Izuo, N., & Shimizu, T. (2017) · Nutrients · doi:10.3390/nu9070645 · Cited by 15 · see citing works

Enzymatic esterification of bixin by l-ascorbic acid

Humeau, C., Rovel, B., & Girardin, M. (2000) · Biotechnology Letters · doi:10.1023/a:1005665913685 · Cited by 14 · see citing works

Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as inhibitors of liver and yeast oxidosqualene cyclase

Ceruti, M., Viola, F., Balliano, G., Milla, P., Roma, G., Grossi, G., & Rocco, F. (2002) · Journal of the Chemical Society Perkin Transactions 1 · doi:10.1039/b200888m · Cited by 9 · see citing works

The Effects of Topical Vitamin C Solution on Burn Wounds Granulation: A Randomized Clinical Trial

Sarpooshi, H. R., Mortazavi, F., Vaheb, M., & Tabarayee, Y. (2016) · Journal of Biomedicine · doi:10.5812/jmb.8301 · Cited by 9 · see citing works

Lipase-catalyzed Synthesis of C-6 Saturated and Unsaturated Fatty Acid Esters of L-Ascorbic Acid

Yang, H. J., Xie, X. J., & Seib, P. A. (2003) · Journal of Applied Glycoscience · doi:10.5458/jag.50.373 · Cited by 7 · see citing works

Cosmetic Dermatology: Requisites in Dermatology

Sheridan, A. T. (2009) · Australasian Journal of Dermatology · doi:10.1111/j.1440-0960.2009.00570.x · Cited by 2 · see citing works

A systematic review of natural products for skin applications: Targeting inflammation, wound healing, and photo-aging

Fernandes, A., Rodrigues, P. M., Pintado, M., & Tavaria, F. K. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154824 · Cited by 264 · see citing works

Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase Dermal Collagen for Skin Antiaging Purposes: Emerging Combination Therapies

Boo, Y. C. (2022) · Antioxidants · doi:10.3390/antiox11091663 · Cited by 219 · see citing works

Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis

PU, S.-Y., Huang, Y.-L., Pu, C., Kang, Y., Hoang, K. D., Chen, K., & Chen, C. (2023) · Nutrients · doi:10.3390/nu15092080 · Cited by 141 · see citing works

Recent advances in squalene: Biological activities, sources, extraction, and delivery systems

Cheng, L., Ji, T., Zhang, M., & Fang, B. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104392 · Cited by 110 · see citing works

Topical delivery of l -ascorbic acid spanlastics for stability enhancement and treatment of UVB induced damaged skin

Elhabak, M. A., Ibrahim, S., & Abouelatta, S. M. (2021) · Drug Delivery · doi:10.1080/10717544.2021.1886377 · Cited by 89 · see citing works

Self-assembled lipid–prodrug nanoparticles

Couvreur, P., Lepêtre‐Mouelhi, S., Garbayo, E., & Blanco‐Prieto, M. J. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00082-0 · Cited by 69 · see citing works

Recombinant Human Collagen-Based Bioinks for the 3D Bioprinting of Full-thickness Human Skin Equivalent

Yang, Y., Xu, R., Wang, C., Guo, Y., Sun, W., & Ouyang, L. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i4.611 · Cited by 67 · see citing works

A comprehensive review and recent advances of vitamin C: Overview, functions, sources, applications, market survey and processes

See, X. Z., Yeo, W. S., & Saptoro, A. (2024) · Process Safety and Environmental Protection · doi:10.1016/j.cherd.2024.04.048 · Cited by 60 · see citing works

Human organ rejuvenation by VEGF-A: Lessons from the skin

Keren, A., Bertolini, M., Keren, Y., Ullmann, Y., Paus, R., & Gilhar, A. (2022) · Science Advances · doi:10.1126/sciadv.abm6756 · Cited by 47 · see citing works

Regulation of Ethanol Assimilation for Efficient Accumulation of Squalene in Saccharomyces cerevisiae

Zhang, Y.-L., Wang, W., Wei, W., Lu, X., Gao, S., Zeng, W., Liu, S., & Zhou, J. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c00515 · Cited by 46 · see citing works

Chitosan-Coated Niosomes Loaded with Ellagic Acid Present Antiaging Activity in a Skin Cell Line

Abd-Elghany, A. A., & Mohamad, E. A. (2023) · ACS Omega · doi:10.1021/acsomega.2c07254 · Cited by 43 · see citing works

Detachable dissolvable microneedles: intra-epidermal and intradermal diffusion, effect on skin surface, and application in hyperpigmentation treatment

Sawutdeechaikul, P., Kanokrungsee, S., Sahaspot, T., Thadvibun, K., Banlunara, W., Limcharoen, B., Sansureerungsikul, T., Rutwaree, T., Oungeun, M., & Wanichwecharungruang, S. P. (2021) · Scientific Reports · doi:10.1038/s41598-021-03503-5 · Cited by 38 · see citing works

Exploring the potential of Halomonas levan and its derivatives as active ingredients in cosmeceutical and skin regenerating formulations

Erginer, M., Gökalsın, B., Tornacı, S., Sesal, C., & Öner, E. T. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124418 · Cited by 35 · see citing works

Synthesis and Cytotoxicity Study of Magnetite Nanoparticles Coated with Polyethylene Glycol and Sorafenib–Zinc/Aluminium Layered Double Hydroxide

Ebadi, M., Buskaran, K., Saifullah, B., Hussein, M. Z., Fakurazi, S., & Pastorin, G. (2020) · Polymers · doi:10.3390/polym12112716 · Cited by 33 · see citing works

Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor

Ghahremani‐Nasab, M., Bakhshayesh, A. R. D., Akbari‐Gharalari, N., & Mehdipour, A. (2023) · Journal of Biological Engineering · doi:10.1186/s13036-023-00380-6 · Cited by 31 · see citing works

Enhanced Therapeutic Applications of Vitamin C via Nanotechnology-Based Pro-Oxidant Properties: A Review

Pal, S., & Jana, N. R. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c03000 · Cited by 25 · see citing works

Lycopene ameliorates skin aging by regulating the insulin resistance pathway and activating SIRT1

Li, J., Zeng, X., Yang, X., & Ding, H. (2022) · Food & Function · doi:10.1039/d2fo01111e · Cited by 23 · see citing works

Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration

Pleguezuelos‐Beltrán, P., Herráiz-Gil, S., Martínez‐Moreno, D., Medraño-Fernández, I., León, C., & Guerrero‐Aspizua, S. (2024) · Cosmetics · doi:10.3390/cosmetics11040121 · Cited by 22 · see citing works

Effect of Penetration Enhancers and Safety on the Transdermal Delivery of Apremilast in Skin

Sarango-Granda, P., Espinoza, L. C., Díaz‐Garrido, N., Alvarado, H. L., Rodríguez-Lagunas, M. J., Baldomà, L., & Calpena, A. C. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14051011 · Cited by 20 · see citing works

Explicating the Multifunctional Roles of Tocotrienol and Squalene in Promoting Skin Health

Morgan, N. R., Magalingam, K. B., Radhakrishnan, A. K., Arumugam, M., Jamil, A., & Bhuvanendran, S. (2024) · Skin Health and Disease · doi:10.1002/ski2.448 · Cited by 19 · see citing works

Prospective and challenges of locally applied repurposed pharmaceuticals for periodontal tissue regeneration

El-Nablaway, M., Rashed, F., Taher, E. S., Abdeen, A., Taymour, N., Soliman, M. M., Shalaby, H. K., Fericean, L. M., Bănățean-Dunea, I., El-Sherbiny, M., et al. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1400472 · Cited by 17 · see citing works

Nanowire-based squalene oleogel repairs skin photoaging

Yan, L., Liu, Z., Zeng, Y., Ji, X., Wang, H., Ni, D., & Pan, M. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03233-0 · Cited by 17 · see citing works

Engineering Saccharomyces cerevisiae for synthesis of β-myrcene and (E)-β-ocimene

Zeng, W., Jiang, Y., Shan, X., & Zhou, J. (2023) · 3 Biotech · doi:10.1007/s13205-023-03818-2 · Cited by 15 · see citing works

Double nutri (Liposomal Encapsulation) enhances bioavailability of vitamin C and extends its half-life in plasma

Wen, C.-J., Chiang, C.-F., Lee, C.-S., Lin, Y.-H., & Tsai, J.-S. (2022) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2022.3274 · Cited by 14 · see citing works

Recent overview of kaffir lime (Citrus hystrix DC) dual functionality in food and nutraceuticals

Budiarto, R., Wathoni, N., Mubarok, S., Hamdani, J. S., Ujilestari, T., Darsih, C., Sari, R. M., Rukmana, R. M., & Sholikin, M. M. (2024) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2024.101384 · Cited by 14 · see citing works

Value-Added Squalene in Single-Cell Oil Produced with Cutaneotrichosporon oleaginosus for Food Applications

Stellner, N. I., Rerop, Z. S., Kyselka, J., Alishevich, K., Beneš, R., Filip, V., Çelik, G., Haack, M., Ringel, M., Masri, M. A., et al. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c01703 · Cited by 13 · see citing works

Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults

Calder, P. C., Kreider, R. B., & McKay, D. L. (2025) · Nutrients · doi:10.3390/nu17020279 · Cited by 12 · see citing works

Comparative Studies on Carbon Paste Electrode Modified with Electroactive Polyamic Acid and Corresponding Polyimide without/with Attached Sulfonated Group for Electrochemical Sensing of Ascorbic Acid

Hwang, J., Bibi, A., Chen, Y.-C., Luo, K.-H., Huang, H.-Y., & Yeh, J. (2022) · Polymers · doi:10.3390/polym14173487 · Cited by 11 · see citing works

Cosmeto-textiles

Singh, M. K., Singh, A., & Morris, H. (2023) · Textile Progress · doi:10.1080/00405167.2023.2258675 · Cited by 10 · see citing works

Development of an ex vivo human skin model and evaluation of biological responses to subcutaneously injected hyaluronic acid formulations

Gou, S., & Kalia, Y. N. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.125490 · Cited by 9 · see citing works

Prevalence and prognostic significance of vitamin C deficiency in patients with acute upper gastrointestinal bleeding: a prospective cohort study

Hui, S., Lim, A. K. H., Koh, E., Abasszade, J. H., Morgan, A., Tan, P. Y., Lemoh, C. N., & Robertson, M. C. (2022) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17359 · Cited by 9 · see citing works

Clinical Investigation of Collagen-Based Electrospun Nanofibers for Enhanced Delivery of Skincare Ingredients

Chand, N. A., Duarah, S., Yuk-Winters, B. A., & Fomra, D. (2024) · Cosmetics · doi:10.3390/cosmetics11010018 · Cited by 9 · see citing works

Progress in the design of ascorbic acid derivative-mediated drug delivery

Lamie, C., Elmowafy, E. M., Attia, D. A., & Mortada, N. D. (2025) · RSC Advances · doi:10.1039/d5ra03825a · Cited by 8 · see citing works

Review: Peningkatan Stabilitas Vitamin C dalam Sediaan Kosmetika

Tonthawi, M., & Musfiroh, I. (2023) · Majalah Farmasetika · doi:10.24198/mfarmasetika.v8i3.44462 · Cited by 8 · see citing works

Nanospanlastic as a promising nanovesicle for drug delivery

Muzammil, S., Mazhar, A., Yeni, D. K., Andleeb, R., Ashraf, A., Shehzad, M. I., Zafar, N., & Mazhar, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91864-0.00007-3 · Cited by 8 · see citing works

Healing Effect of a Nano-Functionalized Medical-Grade Honey for the Treatment of Infected Wounds

Salvo, J., Sandoval, C., Schencke, C., Acevedo, F., & del Sol, M. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15092187 · Cited by 8 · see citing works

Squalene: A High‐Value Compound for COVID ‐19 Vaccine Adjuvants and Beyond Pathways, Production Strategies, and Market Potential

Dasari, D., Singhania, R. R., Bhatia, S. K., Dong, C., & Patel, A. K. (2025) · IUBMB Life · doi:10.1002/iub.70032 · Cited by 7 · see citing works

Topical Application of No-Ozone Cold Plasma in Combination with Vitamin C Reduced Skin Redness and Pigmentation of UV-Irradiated Mice

Nam, S., Choi, J., & Kim, G. (2023) · Biomedicines · doi:10.3390/biomedicines11061563 · Cited by 7 · see citing works

Intra-articular injection of ascorbic acid enhances microfracture-mediated cartilage repair

Chen, Z., Lv, X., Zhang, S., Duan, P., Zhou, T., Yin, Z. B., Dong, S., Lin, H., Pang, R., & Tan, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-54514-x · Cited by 7 · see citing works

Witamina C i jej pochodne w utrzymaniu dobrej kondycji skóry

Goik, U. (2024) · Postępy Biochemii · doi:10.18388/pb.2021_554 · Cited by 6 · see citing works

Клюквенный сок для красоты и здоровья: 9 научных фактов о пользе, противопоказания и особенности употребления

Наталья, Т., & Татьяна, Е. (2023) · Журнал здорового питания и диетологии · doi:10.59316/j.edaplus.2023.25.11 · Cited by 6 · see citing works

The Use of Plants That Seal Blood Vessels in Preparations Applied Topically to the Skin: A Review

Roman, B. H., Muzykiewicz-Szymańska, A., Florkowska, K., Tkacz, M., Wilk, B., Kucharski, Ł., Madalińska, A., & Nowak, A. (2025) · Molecules · doi:10.3390/molecules30091973 · Cited by 5 · see citing works

An Insight into the Cosmetic and Dermatologic Applications of the Molecules of Palmyra Palm

Sayanhika, S., & Selvakumar, P. M. (2024) · Cosmetics · doi:10.3390/cosmetics11060196 · Cited by 4 · see citing works

Bioactive polymers for cosmetics: unleashing the potential of Chromohalobacter canadensis 28

Erginer, M., Yıldız, S. Y., Kambourova, M. S., & Öner, E. T. (2024) · Macromolecular Research · doi:10.1007/s13233-023-00236-4 · Cited by 4 · see citing works

The Molecular Mechanism of Propylene Glycol Monocaprylate on Skin Retention: Probing the Dual Roles on the Molecular Mobility and Collagen Connection in Roflumilast Cream

Liu, Y., Liu, C., Jia, W., Xu, W., Quan, P., & Fang, L. (2022) · AAPS PharmSciTech · doi:10.1208/s12249-022-02284-y · Cited by 4 · see citing works

Emergence of New Concepts in Skin Physiopathology through the Use of in vitro Human Skin Explants Models

Cousin, I., Misery, L., de Vries, P., & Lebonvallet, N. (2023) · Dermatology · doi:10.1159/000533261 · Cited by 3 · see citing works

The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Study

Wang, Y., Zhu, W., Luo, W., Ma, Y., & Yue, Z. (2025) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70565 · Cited by 3 · see citing works

The battle against skin aging: Advances in natural anti-aging compounds and innovative delivery systems

Zhang, S., Guo, X., Hao, L., Jiang, Y., Chen, Z., Wang, J., 冉柳毅, Yang, Y., Wang, Y., Wang, Y., et al. (2026) · Chinese Chemical Letters · doi:10.1016/j.cclet.2026.112503 · Cited by 3 · see citing works

Narrative Review: Herbal Nanospray Sebagai Anti-Aging

Pratiwi, M. W., Wijaya, T. H., Sumayyah, S., & Kurniawan, D. W. (2023) · Majalah Farmasetika · doi:10.24198/mfarmasetika.v8i3.45705 · Cited by 3 · see citing works

Ex Vivo Patient-Derived Explant Model for Neurofibromatosis Type 1–Related Cutaneous Neurofibromas

Grit, J. L., Turner, L., Essenburg, C. J., Gallik, K. L., Dischinger, P. S., Shurlow, N. D., Pate, M. J., Graveel, C. R., & Steensma, M. R. (2024) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.01.032 · Cited by 3 · see citing works

Biocompatible mesoporous silica: A novel nanomaterial for skin wound healing

Hong, Y., Su, Q., Wu, X., Zhang, Q., Sun, J., Wang, Y., & Su, J. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.111846 · Cited by 3 · see citing works

Facial Treatment with 3-O-Cetyl Ascorbic Acid for Improvement of Skin Texture: Uptake, Effectiveness, and In Vitro Carcinogenicity Assessment

Doi, N., Yamada, Y., Toyoshima, M., Kondo, Y., Nakaoji, K., Hamada, K., & Tatsuka, M. (2021) · Cosmetics · doi:10.3390/cosmetics8020038 · Cited by 3 · see citing works

Functional and molecular insights in topical wound healing by ascorbic acid

Jha, B., Majie, A., Roy, K., & Gorain, B. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04180-1 · Cited by 2 · see citing works

Effects of hypobaric hypoxia during a simulated ultra‐long‐haul flight on inflammation and regeneration after muscle trauma and muscle trauma‐hemorrhagic shock

Zhang, L., Voss, J. G., Soulakova, J. N., & Schneider, B. S. P. (2023) · Muscle & Nerve · doi:10.1002/mus.27795 · Cited by 2 · see citing works

Fructans in Personal Care Products

Hasköylü, M. E., & Öner, E. T. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85410-8.00013-2 · Cited by 2 · see citing works

Magnesium Compounds Increase Aquaporin‐3 in Human Epidermal Keratinocyte HaCaT Cells

Ikarashi, N., Kawai, H., Shinozaki, Y., Tabata, K., Yoshida, R., Nishinaka, Y., Kon, R., Sakai, H., & Hosoe, T. (2023) · Dermatologic Therapy · doi:10.1155/2023/8896599 · Cited by 2 · see citing works

Fixed-dose combinations in pharmacotherapy of chronic venous diseases

Bogachev, V. Y., Boldin, B. V., Витальевич, К. К., & Dzhenina, O. V. (2024) · Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) · doi:10.21518/akh2024-042 · Cited by 2 · see citing works

Binding of collagen I to integrins alleviates UVB-caused mitochondrial disorders in human keratinocytes HaCaT through enhancement of F-actin polymerization

Zhu, Y., Ji, T., San, Z., Cao, R., Hayashi, T., Mizuno, K., Hattori, S., Fujisaki, H., Liu, W., & Ikejima, T. (2025) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2025.113170 · Cited by 2 · see citing works

Collagen supplementation - does it bring real benefits?

Kaziród, K., Hunek, A. K., Zapała, M. A., Wiśniewska-Skomra, J., Chmielarz, K., Tylutka, K., & Hapon, A. (2023) · Quality in Sport · doi:10.12775/qs.2023.13.01.008 · Cited by 2 · see citing works

New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system

Adamus, J., Abram, K., Banaś, P., Pierzchała, J. R., Bednarz, K., Sobańska, N., Banasiak, A. P., Teichman, R., Kasprowicz, J., & Hyjek, M. (2023) · Journal of Education Health and Sport · doi:10.12775/jehs.2023.13.03.031 · Cited by 2 · see citing works

A Bio-Therapeutically Squalene

Aslam, M. S., Kim, Y. J., & Linchao, Q. (2023) · Advances in medical education, research, and ethics (AMERE) book series · doi:10.4018/978-1-6684-7828-8.ch004 · Cited by 2 · see citing works

Bioactive Compounds for Topical and Minimally Invasive Cellulite Treatment and Skin Rejuvenation

Rusu, A., Mazilu, R.-D., Székely-Szentmiklósi, B., Moldovan, O.-L., Tanase, C., Lungu, I.-A., & Hancu, G. (2026) · Cosmetics · doi:10.3390/cosmetics13010035 · Cited by 1 · see citing works

The role of vitamin C in skin care and health

Skibska, B., Gorąca, A., & Markowicz-Piasecka, M. (2023) · Farmacja Polska · doi:10.32383/farmpol/177269 · Cited by 1 · see citing works

A Digital Image Analysis of the Morphology and Immunolocalization of Catalase and Caspase-3 in the Skin of Adult Male Rats After Treatment with Letrozole and Vitamin C

Pilutin, A., Łukasiewicz, J., Rzeszotek, S., Misiakiewicz-Has, K., & Wilk, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178645 · Cited by 1 · see citing works

Targeted lipidome analysis reveals nutritionally enhanced foxtail millet genotypes across diverse grain colours

Palakurthi, R., Seni, S., Singh, R. K., Pandey, A., & Prasad, M. (2025) · The Nucleus · doi:10.1007/s13237-025-00602-w · Cited by 1 · see citing works

Exploring Squalene's Impact on Epidermal Thickening and Collagen Production: Molecular Docking Insights

Safaei, M., Goodarzi, A., Noori, F., Farmani, A. R., Kouhpayeh, S. A., & Abpeikar, Z. (2024) · Current Signal Transduction Therapy · doi:10.2174/0115743624288465240307062332 · Cited by 1 · see citing works

Ascorbic Acid Injection Efficacy to Increase Skin Collagen

Anggraini, E., & Damayanti, P. A. A. (2024) · Jurnal Penelitian Pendidikan IPA · doi:10.29303/jppipa.v10i6.5282 · Cited by 1 · see citing works

Biocompatibility of Kaffir lime fruit juice powered ZnO nanoparticles in earthworm, Eudrilus eugeniae: A green biomimetic approach

Paventhan, S., Kavitha, P., Balasubramanian, T., Ayyanar, M., Kavitha, V. S., Amalraj, S., Sripriya, R., Rajagopal, R., & Alfarhan, A. (2024) · BioResources · doi:10.15376/biores.20.1.1345-1364 · Cited by 1 · see citing works

Correlation Analysis of Serum Vitamin C and Pelvic Organ Prolapse in Middle-Aged and Elderly Women: Based on NHANES Database

Zhou, Z., Wei, Q., Luo, J., Zheng, J., Ye, Q., Fan, X. D., & Fang, M. (2025) · Gynecologic and Obstetric Investigation · doi:10.1159/000544539 · Cited by 1 · see citing works

Fixed-dose ruscus extract combination and its place in current clinical guidelines for the treatment of chronic venous diseases

Bogachev, V. Y., Boldin, B. V., Витальевич, К. К., Abdosh, R., Kopnenkova, D. K., & Dzhenina, O. V. (2025) · Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) · doi:10.21518/akh2025-023 · Cited by 1 · see citing works

Metal Nanoparticles for Dermatology and Cosmetics

Patel, A., Enman, J., Rova, U., Christakopoulos, P., & Μάτσακας, Λ. (2022) · Nanotechnology in the life sciences · doi:10.1007/978-3-030-82918-6_3

Análise do produto botox caps da life natural

Rodrigues, F. D. A. A., & López, D. (2022) · Ciencia Latina Revista Científica Multidisciplinar · doi:10.37811/cl_rcm.v6i1.1719

ANÁLISE DO PRODUTO BOTOX CAPS DA LIFE NATURAL®

Rodrigues, F. D. A. A., & López, D. (2021) · COGNITIONIS Scientific Journal · doi:10.38087/2595.8801.96

Сок брокколи — один из наиболее полезных фрешей для здоровья взрослых и малышей

Наталья, Т., & Татьяна, Е. (2023) · Журнал здорового питания и диетологии · doi:10.59316/.vi23.224

Сок киви — 8 веских причин добавить в свой рацион

Татьяна, Е., & Наталья, Т. (2023) · Журнал здорового питания и диетологии · doi:10.59316/.vi23.221

Сок маракуйи — 7 научных фактов о пользе экзотического напитка

Анна, Ш., & Татьяна, Е. (2023) · Журнал здорового питания и диетологии · doi:10.59316/.vi23.222

Сок помело — экзотический напиток здоровья и долголетия

Анна, Ш., & Татьяна, Е. (2022) · Журнал здорового питания и диетологии · doi:10.59316/.vi22.212

Мандариновый сок: 7 полезных свойств вкусного напитка

Анна, Ш., & Татьяна, Е. (2022) · Журнал здорового питания и диетологии · doi:10.59316/.vi22.209

EFFECT OF HEAT PROCESSING ON VITAMIN COMPOSITION OF SELECTED STAPLE GREEN LEAFY VEGETABLES IN NIGERIA

Adeniyi, S. A., Agbugui, P., SOLOLA, S. O. A., & OYEKU, J. S. (2023) · Food and Environment Safety Journal · doi:10.4316/fens.2023.023

Synergistic therapy for skin aging: The association of the microneedling technique and vitamin C from the point of view of orofacial harmonization

Silveira, F. P. D. M., Teixeira, J. D. A., Santos, I. T., de Morais, R. P. L., Araújo, G. M., Correia, D. L. D. N., & Moreira, A. G. (2024) · Seven Editora eBooks · doi:10.56238/sevened2024.007-048

Treatment of Chronic Pancreatitis via Nutraceuticals

Jindal, D., Pancham, P., & Singh, M. (2024) · Food bioactive ingredients · doi:10.1007/978-3-031-76481-3_7

Vitamin C-induced DNA Cleavage Using Curcumin-loaded Fe3O4-silane Magnetic Nanoparticles

Prabakaran, N., Mareeswaran, P. M., & Shanmugavelan, P. (2024) · Current Physical Chemistry · doi:10.2174/0118779468346682241127050249

Lipid-drug conjugates: conjugation methods and therapeutic benefits

Singha, L. R., Das, S., & Das, M. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33382-8.00002-9

A comparison of normalization methods for the expression of genes associated with oxidative stress in the liver of sheep

Babington, S., Ding, L., Tilbrook, A. J., Maloney, S. K., & Blache, D. (2025) · BMC Genomic Data · doi:10.1186/s12863-025-01345-y

USING SQUALENE TO DEVELOP EFFECTIVE MEDICINES

Koroleva, Y., Kirillova, D., Kuvakin, S., Putenikhina, D., Nikulin, A., Gromakova, A. I., & Shatalov, D. (2025) · Problems of Biological Medical and Pharmaceutical Chemistry · doi:10.29296/25877313-2025-07-01

In Vivo Biostimulatory Efficacy of Ascorbic Acid-Loaded Poly(lactic-co-glycolic Acid) Nanoparticles Hydrogel for Dermal Remodeling

Colaço, A. R. A., Furtado, P. D. S., Vanzan, D. F., da Silva, N. S., do Carmo, F. A., Cabral, L. M., Simon, A., Esteves, J. C., & Sathler, P. C. (2025) · ACS Omega · doi:10.1021/acsomega.5c01910

Effects of Vitamin C Supplementation on Histology of Callus Diameter and Osteoblast Number in Male Wistar Rats With Complete Femur Bone Fracture

Rambe, S. R., Putra, R. M., & Rahmadhany, H. (2025) · Journal of Biomedicine and Translational Research · doi:10.14710/jbtr.v11i1.25888

VITAMINA C EM COSMÉTICOS FACIAIS: CONTRIBUIÇÃO PARA O REJUVENESCIMENTO CUTÂNEO

da Silva, F. F., & dos Santos, V. M. (2025) · Revista Foco · doi:10.54751/revistafoco.v18n11-225

Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin

Wang, Z., Zhu, J., Wang, Y., Hu, T., Chen, S., Xu, S., Li, Y., Liao, X., Liang, S., Li, Y. E., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2026.01.069

Application of squalenoylation in chronic pain alleviation

Silva, A. D. (2023) · doi:10.70675/83a7bd41z85b4z4dcazaa47z92efc29ff8da

Drug Discovery Targeting Nicotinic Acetylcholine Receptors for Hearing Loss

Oman, J., Sapkota, P., Mateen, S., Schulte, M., & Pashikanti, S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083614

Synthesis of closo-Decaborate‒Squalene Conjugates and Self-Association Capability Studies

Kalistratova, A. V., Tomilina, A. Y., Kubasov, A. S., Golubev, A. V., Kryschenko, Y. K., Zhizhin, K. Y., Kuznetsov, N. T., & Николаевич, О. Е. (2026) · Russian Journal of Inorganic Chemistry · doi:10.1134/s0036023626600851

Layer-by-layer engineered phytosomal nanocarriers for improved stability and skin localization of labile hydrophilic molecules

Mokles, R. M., Taha, M. S., & Abdelbary, G. A. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108718

Medicinal plants

Toma, E., Beloukas, A., & Letsiou, S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27500-5.00017-4

Innovative Functional Gummies with Caffeine and Collagen: Formulation and Physicochemical Properties

Ciurzyńska, A., Zwierzchowski, J., Janowicz, M., Karwacka, M., & Galus, S. (2026) · Applied Sciences · doi:10.3390/app162110806

Schizochytrium spp. as Multi-Product Marine Biofactories for Health and Nutritional Applications: Mechanisms and Future Biorefinery Perspectives

Shafiq, M., Alam, A., & Zeb, L. (2026) · Marine Drugs · doi:10.3390/md24110390

Morphogenesis of dermal-epidermal junction in a model of reconstructed skin: Beneficial effects of vitamin C

Marionnet, C., Vioux‐Chagnoleau, C., Pierrard, C., Sok, J., Asselineau, D., & Bernerd, F. (2006) · Experimental Dermatology · doi:10.1111/j.1600-0625.2006.00454.x · Cited by 57 · see citing works

Effect of vitamin C and its derivatives on collagen synthesis and cross‐linking by normal human fibroblasts

Boyera, N., Galey, I., & Bernard, B. A. (1998) · International Journal of Cosmetic Science · doi:10.1046/j.1467-2494.1998.171747.x · Cited by 154 · see citing works

Synthesis and Biological Evaluation of Ascorbyl-Conjugated Peptide Derivatives as Collagen Synthesis Stimulating Agents in Human Skin Fibroblasts

Park, K.-Y., & Kim, J. (2020) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-020-10041-7 · Cited by 6 · see citing works

Vitamin C, gene expression and skin health

Duarte, T. L., & Almeida, I. F. (2012) · Wageningen Academic Publishers eBooks · doi:10.3920/9789086867295_008 · Cited by 2 · see citing works

Witamina C i jej pochodne w utrzymaniu dobrej kondycji skóry

Goik, U. (2024) · Postępy Biochemii · doi:10.18388/pb.2021_554 · Cited by 6 · see citing works