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Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography
Open accessPublished version of a preprint
Abstract
Computed tomography (CT) is the preferred imaging method for diagnosing 2019 novel coronavirus (COVID19) pneumonia. We aimed to construct a system based on deep learning for detecting COVID-19 pneumonia on high resolution CT. For model development and validation, 46,096 anonymous images from 106 admitted patients, including 51 patients of laboratory confirmed COVID-19 pneumonia and 55 control patients of other diseases in Renmin Hospital of Wuhan University were retrospectively collected. Twenty-seven prospective consecutive patients in Renmin Hospital of Wuhan University were collected to evaluate the efficiency of radiologists against 2019-CoV pneumonia with that of the model. An external test was conducted in Qianjiang Central Hospital to estimate the system’s robustness. The model achieved a per-patient accuracy of 95.24% and a per-image accuracy of 98.85% in internal retrospective dataset. For 27 internal prospective patients, the system achieved a comparable performance to that of expert radiologist. In external dataset, it achieved an accuracy of 96%. With the assistance of the model, the reading time of radiologists was greatly decreased by 65%. The deep learning model showed a comparable performance with expert radiologist, and greatly improved the efficiency of radiologists in clinical practice.
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Metadata
- Authors
- Chen, J., Wu, L., Zhang, J., Zhang, L., Gong, D., Zhao, Y., Chen, Q., Huang, S., Yang, M., Yang, X., Hu, S., Wang, Y., Hu, X., Zheng, B., Zhang, K., Wu, H., Dong, Z., Xu, Y., Zhu, Y., Chen, X., Zhang, M., Yu, L., Cheng, F., & Yu, H.
- Venue
- Scientific Reports
- Published
- 2020-11-05
- Volume
- 10
- Issue
- 1
- Pages
- 19196-19196
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W3096956107
- Cited by
- 675
- References
- 9
- FWCI
- 64.21
- Type
- journal article
- Language
- en
- Open access
- gold
- Licence
- creativecommons.org/licenses/by/4.0 (tdm)
- creativecommons.org/licenses/by/4.0 (vor)
- Funders
- Project of Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision (2018BCC337)
- Hubei Province Major Science and Technology Innovation Project (2018-916-000-008)
- the National Natural Science Foundation of China (81672387)
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