Effect of vitamin E supplementation on cardiometabolic risk factors, inflammatory and oxidative markers and hormonal functions in PCOS (polycystic ovary syndrome): a systematic review and meta‐analysis
Open accessAbstract
Polycystic ovary syndrome (PCOS) is a common endocrinopathy among reproductive-age women. Various therapeutical approaches are currently used to manage or control symptoms associated with PCOS. This systematic review intended to assess the effects of Vit E supplementation on cardiometabolic risk factors, inflammatory and oxidative markers, and hormonal functions in PCOS women based on the clinical trial's results. The databases including PubMed, Scopus, Cochrane, Web of Science, and Embase were used to find all relevant studies. The authors reviewed all relevant clinical trials via systematic evaluation of abstracts and titles. Searches were conducted on August 1, 2020. After the initial search and reading of the article's title and abstract, 353 articles were reviewed; finally, 12 articles met the inclusion criteria. Vitamin E supplementation improves lipid profile, decreases insulin and HOMA-IR levels. Furthermore, while Vitamin E supplementation decreases LH and testosterone concentrations, it increases FSH and progestrone concentrations. The following meta-analysis showed that vitamin E supplementation made statistically significant improvements in triglyceride (TG) and low-density lipoproteins (LDL) levels, meanwhile, pooled mean difference for waist circumference (WC) and HOMA-IR were also statistically significant. Supplementary regimens containing vitamin E can positively affect metabolic and hormonal parameters in women with PCOS.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Vitamin E alone significantly diminishes the risk of PCOS and associated conditions such as hyperlipidemia and insulin resistance.
“More than that, it has also been evidenced that vitamin E alone significantly diminishes the risk of PCOS, and other associated conditions, such as hyperlipidemia and insulin resistance.”
From Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management (2025) · cites this paper as [134]
The Outcomes section on insulin resistance explicitly says vitamin E alone did not have the significant effect seen with CoQ10 supplementation. The lipid-profile findings concern vitamin E combined with magnesium, CoQ10, or omega-3, not vitamin E alone. The review studies outcomes in people already diagnosed with PCOS, rather than a reduction in their risk of developing it. (LLM, conf=0.88)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guyatt, G. H., Oxman, A. D., Vist, G. E., Kunz, R., Falck-Ytter, Y., Alonso-Coello, P., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39489.470347.ad · Cited by 23,305 · see citing works
Wang, G., Ma, R., Qiao, G., Wada, K., Aizawa, Y., & Satoh, T. (2015) · Integrative Medicine International · doi:10.1159/000368408 · Cited by 18,759 · see citing works
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Witchel, S. F., Oberfield, S., Rosenfield, R. L., Codner, E., Bonny, A., Ibáñez, L., Pena, A., Horikawa, R., Gomez-Lobo, V., Joel, D., et al. (2015) · Hormone Research in Paediatrics · doi:10.1159/000375530 · Cited by 3,113 · see citing works
The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population
Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yıldız, B. O. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032046 · Cited by 2,715 · see citing works
Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence
Niki, E. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.03.022 · Cited by 677 · see citing works
Polycystic ovarian syndrome (PCOS): Long-term metabolic consequences
Anagnostis, P. G., Tarlatzis, B. C., & Kauffman, R. P. (2017) · Metabolism · doi:10.1016/j.metabol.2017.09.016 · Cited by 429 · see citing works
Insulin resistance, polycystic ovary syndrome, and type 2 diabetes mellitus
Ovalle, F., & Azziz, R. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)03111-4 · Cited by 428 · see citing works
Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline
Teede, H. J., Misso, M. L., Deeks, A. A., Moran, L. J., Stuckey, B. G. A., Wong, J. L. A., Norman, R. J., Costello, M. F., & Groups, O. B. O. T. G. D. (2011) · Medical Journal of Australia · doi:10.5694/mja11.10915 · Cited by 379 · see citing works
Pathophysiology and types of dyslipidemia in PCOS
Diamanti‐Kandarakis, E., Papavassiliou, A. G., Kandarakis, S., & Chrousos, G. P. (2007) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.07.004 · Cited by 301 · see citing works
The pathophysiology of polycystic ovary syndrome
Tsilchorozidou, T., Overton, C. E., & Conway, G. S. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01842.x · Cited by 295 · see citing works
Inflammation and Human Ovarian Follicular Dynamics
Boots, C. E., & Jungheim, E. S. (2015) · Seminars in Reproductive Medicine · doi:10.1055/s-0035-1554928 · Cited by 255 · see citing works
Dyslipidemia and Oxidative Stress in PCOS
Μacut, D., Bjekić-Macut, J., & Savic-Radojevic, A. R. (2012) · Frontiers of hormone research · doi:10.1159/000341683 · Cited by 139 · see citing works
Shorakae, S., Teede, H., de Courten, B., Lambert, G., Boyle, J., & Moran, L. (2015) · Seminars in Reproductive Medicine · doi:10.1055/s-0035-1556568 · Cited by 115 · see citing works
Chakraborty, P., Ghosh, S., Goswami, S. K., Kabir, S. N., Chakravarty, B., & Jana, K. (2013) · Biological Trace Element Research · doi:10.1007/s12011-012-9592-5 · Cited by 99 · see citing works
Izadi, A., Ebrahimi, S., Shirzai, S., Taghizadeh, S., Parizad, M., Farzadi, L., & Gargari, B. P. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01221 · Cited by 96 · see citing works
Rahmani, E., Samimi, M., Ebrahimi, F. A., Foroozanfard, F., Ahmadi, S., Rahimi, M., Jamilian, M., Aghadavod, E., Bahmani, F., Taghizadeh, M., et al. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.09.008 · Cited by 83 · see citing works
Jamil, A. S., Alalaf, S., Al-Tawil, N. G., & Al‐Shawaf, T. (2015) · Reproductive Health · doi:10.1186/1742-4755-12-7 · Cited by 80 · see citing works
Sepidarkish, M., Akbari‐Fakhrabadi, M., Daneshzad, E., Yavari, M., Rezaeinejad, M., Morvaridzadeh, M., & Heshmati, J. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.05.004 · Cited by 72 · see citing works
Work-family balance and the subjective well-being of rural women in Sichuan, China
Shui, Y., Xu, D., Liu, Y., & Liu, S. (2020) · BMC Women s Health · doi:10.1186/s12905-019-0871-6 · Cited by 72 · see citing works
Jamilian, M., Shojaei, A., Samimi, M., Ebrahimi, F. A., Aghadavod, E., Karamali, M., Taghizadeh, M., Jamilian, H., Alaeinasab, S., Jafarnejad, S., et al. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.12.049 · Cited by 71 · see citing works
Ebrahimi, F. A., Samimi, M., Foroozanfard, F., Jamilian, M., Akbari, H., Rahmani, E., Ahmadi, S., Taghizadeh, M., Memarzadeh, M. R., & Asemi, Z. (2017) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0042-117773 · Cited by 64 · see citing works
Panti, A., Shehu, C. E., Saidu, Y., Tunau, K. A., Nwobodo, E. I., Jimoh, A. O., Bilbis, L. S., Umar, A. B., & Hassan, M. (2018) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20181892 · Cited by 52 · see citing works
Shokrpour, M., & Asemi, Z. (2018) · Biological Trace Element Research · doi:10.1007/s12011-018-1602-9 · Cited by 52 · see citing works
Chen, J., Guo, Q., Pei, Y., Ren, Q., Chi, L., Hu, R., & Tan, Y. (2020) · BMC Women s Health · doi:10.1186/s12905-020-00930-w · Cited by 51 · see citing works
[The effects of oxidative stress to PCOS].
Zhang, D., Luo, W., Liao, H., Wang, C., & Sun, Y. X. (2008) · PubMed · Cited by 50 · see citing works
Izadi, A., Shirazi, S., Taghizadeh, S., & Gargari, B. P. (2019) · Archives of Medical Research · doi:10.1016/j.arcmed.2019.04.004 · Cited by 48 · see citing works
Hager, M., Nouri, K., Imhof, M., Egarter, C., & Ott, J. (2019) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-019-05194-w · Cited by 35 · see citing works
Jamilian, M., Sabzevar, N. K., & Asemi, Z. (2018) · Hormone and Metabolic Research · doi:10.1055/a-0749-6431 · Cited by 33 · see citing works
Sadeghi, F., Naeini, A. A., Mardanian, F., Ghazvini, M. R. A., & Mahaki, B. (2019) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000588 · Cited by 27 · see citing works
Talari, H. R., Poladchang, S., Hamidian, Y., Samimi, M., Gilasi, H. R., Ebrahimi, F. A., & Asemi, Z. (2018) · Oman Medical Journal · doi:10.5001/omj.2018.88 · Cited by 26 · see citing works
Dou, M., Ma, A., Wang, Q. Z., Liang, H., Li, Y., Yi, X. M., & Zhang, S. C. (2009) · Nutrition Research · doi:10.1016/j.nutres.2009.07.001 · Cited by 25 · see citing works
Asbaghi, O., Choghakhori, R., & Abbasnezhad, A. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.07.001 · Cited by 18 · see citing works
[Effects of vitamin E and magnesium on glucolipid metabolism in obese rats ].
Chang, W., Ma, A., Wang, Q., Mao, R., & Li, C. (2014) · PubMed · Cited by 7 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- [2]Izadi A Hormonal and metabolic effects of coenzyme Q10 and/or vitamin E in patients with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 2019 104 2 319 327 30202998
- [17]Ebrahimi FA The effects of omega-3 fatty acids and vitamin E co-supplementation on indices of insulin resistance and hormonal parameters in patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial Hormone Metab. Res. 2017 125 06 353 359 28407657
- [30]Shokrpour, M. & Asemi, Z. The effects of magnesium and vitamin E co-supplementation on hormonal status and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome. 191(1), 54–60 (2019). 30565017
- [35]Rahmani E The effects of omega-3 fatty acids and vitamin E co-supplementation on gene expression of lipoprotein (a) and oxidized low-density lipoprotein, lipid profiles and biomarkers of oxidative stress in patients with polycystic ovary syndrome Mol. Cell. Endocrinol. 2017 439 247 255 10.1016/j.mce.2016.09.008 27619403 · DOI
Cited by
Sorted by citations
Zhao, H., Zhang, J., Cheng, X., Nie, X., & He, B. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-022-01091-0 · Cited by 408 · see citing works
Suha, S. A., & Islam, M. N. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e14518 · Cited by 84 · see citing works
Muhammed Saeed, A. A., Noreen, S., Awlqadr, F. H., Farooq, M. I., Qadeer, M., Rai, N., Farag, H. A., & Saeed, M. N. (2025) · Journal of Health, Population and Nutrition · doi:10.1186/s41043-025-00899-y · Cited by 29 · see citing works
“This is in line with the fact that E vitamin fortification promotes the synthesis of good lipids, lowers insulin levels, and helps to counteract the harmful oxidation process in PCOS [134] .”
The Effect of Vitamin E Supplementation in Postmenopausal Women—A Systematic Review
Feduniw, S., Korczyńska, L., Górski, K., Zgliczyńska, M., Bączkowska, M., Byrczak, M., Kociuba, J., Ali, M. K., & Ciebiera, M. (2022) · Nutrients · doi:10.3390/nu15010160 · Cited by 26 · see citing works
Suha, S. A., & Islam, M. N. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e20524 · Cited by 22 · see citing works
Dietary supplements in polycystic ovary syndrome–current evidence
Han, Y., Hou, Y., Han, Q., Yuan, X., & Chen, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1456571 · Cited by 19 · see citing works
Zhou, J., Zuo, W., Tan, Y., Wang, X., Zhu, M., & Zhang, H. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-023-01130-4 · Cited by 16 · see citing works
Yifu, P. (2023) · BMC Medical Genomics · doi:10.1186/s12920-023-01581-0 · Cited by 11 · see citing works
Chen, B., Li, Y., Li, Z., Hu, X., Zhen, H., Chen, H., Nie, C., Hou, Y., Zhu, S., Xiao, L., et al. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.103964 · Cited by 9 · see citing works
Shen, J.-Y., Xu, L., Ding, Y., & Wu, X.-Y. (2023) · World Journal of Clinical Cases · doi:10.12998/wjcc.v11.i23.5468 · Cited by 7 · see citing works
Li, Y., Yatsuya, H., Wang, C., Uemura, M. Y., Matsunaga, M., He, Y., Khine, M. T., & Ota, A. (2022) · Nutrients · doi:10.3390/nu14153019 · Cited by 9 · see citing works
Wang, R., Huang, K., Wang, M., Zou, W., Huang, Y., Jiang, W., Feng, Y., Shen, H., & Lei, X. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1705284 · Cited by 6 · see citing works
Askarpour, M., Hejazi, N., Jahromi, B. N., Eskandari, M. H., Famouri, M., & Bedeltavana, A. (2025) · Preventive Nutrition and Food Science · doi:10.3746/pnf.2025.30.1.37 · Cited by 5 · see citing works
Emamat, H., Boushehri, S. N., Eslami, M. A., Totmaj, A. S., & Ghalandari, H. (2022) · Phytotherapy Research · doi:10.1002/ptr.7698 · Cited by 5 · see citing works
Wang, R., Miao, C., Chen, Y., Zhao, Y., Yang, L., Cheng, W., & Zhang, Q. (2022) · Gynecological Endocrinology · doi:10.1080/09513590.2022.2148648 · Cited by 5 · see citing works
Function of MicroRNAs in Normal and Abnormal Ovarian Activities: A Review Focus on MicroRNA-21
Arefnezhad, R., Roghani-Shahraki, H., Motedayyen, H., & Rezaei-Tazangi, F. (2024) · International Journal of Fertility and Sterility · doi:10.22074/ijfs.2023.1985792.1415 · Cited by 10 · see citing works
Ren, X., Wu, W., Li, Q., Li, W., Wang, X., & Wang, G. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1464959 · Cited by 5 · see citing works
Begum, R. F., & Mohan, S. (2024) · Future Science OA · doi:10.2144/fsoa-2023-0245 · Cited by 5 · see citing works
Zhang, Y., Shi, B., Tian, Y., XU, S., & Chang, H. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1697275 · Cited by 4 · see citing works
Olaniyan, O. T., Dare, A., Adetunji, C. O., Okotie, G. E., Dare, J. B., Adigun, B. M., & Adebayo, F. (2023) · Asian Pacific Journal of Reproduction · doi:10.4103/2305-0500.372379 · Cited by 4 · see citing works
Al‐Sowayan, N. S., & Almarzougi, R. A. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4820333 · Cited by 4 · see citing works
Nandagopal, P. B., Jayakrishnan, G., Kaithamattathil, A. V., & Manickam, V. (2026) · Frontiers in Reproductive Health · doi:10.3389/frph.2026.1821411 · Cited by 3 · see citing works
Hosseini, S. F., Khodaei, F., Hasansagha, Z., Khosravizadeh, H., Abdollahi, M., & Azaryan, E. (2023) · Jundishapur Journal of Natural Pharmaceutical Products · doi:10.5812/jjnpp-137193 · Cited by 4 · see citing works
Chen, Z., Jing, S., & Sun, Y. (2023) · Medicine · doi:10.1097/md.0000000000036791 · Cited by 2 · see citing works
Hosseini, S. F., Khodaei, F., Hasansagha, Z., Khosravizadeh, H., Abdollahi, M., & Azaryan, E. (2023) · Preprints.org · doi:10.20944/preprints202304.0299.v1 · Cited by 3 · see citing works
Askarpour, M., Jahromi, B. N., Eskandari, M. H., Maghsoudi, Z., Famouri, M., Bedeltavana, A., & Hejazi, N. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70506 · Cited by 2 · see citing works
Bakırhan, E. G., & Kaplan, S. (2025) · Histochemistry and Cell Biology · doi:10.1007/s00418-025-02399-w · Cited by 2 · see citing works
Chiarot, A., Minhas, M., de Maat, N. M., Doan, J., Nilsson, M. I., Hettinga, B. P., Faghih, M., Neal, M. S., Nederveen, J. P., & Tarnopolsky, M. A. (2025) · Biomolecules · doi:10.3390/biom15091258 · Cited by 2 · see citing works
Begum, R. F., Suresh, S., Devi, V. S., Moka, M. K., & Mohan, S. (2023) · Current Traditional Medicine · doi:10.2174/2215083810666230828113447 · Cited by 2 · see citing works
Polycystic Ovary Syndrome PCOS and Depression Role of Neuroinflammation
Ramezanpour, M. R., Bahrami, O., Pashazadeh, M., Sarallah, R., Nikfar, R., & Zolbin, M. M. (2025) · IGI Global eBooks · doi:10.4018/979-8-3693-5908-2.ch007 · Cited by 1 · see citing works
Ahmed, R., Yashmin, R., Kalita, J. C., Sarma, H., & Das, A. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202500877 · Cited by 1 · see citing works
Zhou, Q., Huang, B., Wei, Y., Wang, R., Lei, X., Chen, X., & Huang, K. (2025) · Middle East Fertility Society Journal · doi:10.1186/s43043-025-00264-3 · Cited by 1 · see citing works
Bai, C., & Liu, J. (2026) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-026-05264-2 · Cited by 1 · see citing works
Aditya, R., Santoso, B. I., & Widjiati Widjiati, W. (2023) · Pharmacognosy Journal · doi:10.5530/pj.2023.15.154
Mohsen, A. M., AL-Azawi, R. S., Naji, H. H., Kzar, H. H., & Al-Gazally, M. E. (2022) · Bionatura · doi:10.21931/rb/2022.07.03.51
Blanco, A. C., Duarte, A., & Arango, F. O. D. (2023) · Encuentro Internacional de Educación en Ingeniería · doi:10.26507/paper.2878
Na’im, N. A. M. (2023) · International Journal of Pharmaceuticals Nutraceuticals and Cosmetic Science · doi:10.24191/ijpnacs.v6i1.01
Fat Soluble Vitamins in the Ocular, Cardiac, and Infectious Diseases: Myths and Misconceptions
Sepehri, Z., Sargazi, A., Yousefi, M., Sarhaddi, F., Sepehri, M., Behzadi, A., Etemadi, S., Hedayatipour, M., Moghaddam, Y. A., Aghdam, N. J., et al. (2024) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-55489-6_2
The role of vitamin E in the management of polycystic ovarian syndrome
Razzaq, S. T. A., Al-Diwan, J. K., Hasan, N. D., & Hameed, R. J. (2024) · International Journal of Advanced Academic Studies · doi:10.33545/27068919.2024.v6.i5b.1178
Alimoradi, H., Mashhadi, F., Hemmat, A., Mohsen, N., Khosravi, M., Maryam, E., Ghaebi, N. K., & Roudi, F. (2024) · Archive of Food and Nutritional Science · doi:10.29328/journal.afns.1001061
Macronutrients and Disease: Polycystic Ovary Syndrome
Tehrani, F. R., & Naz, M. S. G. (2025) · Springer eBooks · doi:10.1007/978-3-031-32047-7_28-1
REPERCUSSÕES CARDIOMETABÓLICAS DA SÍNDROME DOS OVÁRIOS POLICÍSTICOS
Lima, R. M. N., Silva, I. M. L., Andrade, G. M., Gomes, F., de Carvalho, T. B. D., Nery, W. D. S., & Vasconcelos, Y. L. C. (2025) · Revista Foco · doi:10.54751/revistafoco.v18n4-051
Zhang, Y., Wang, Y., Wang, S., & Zhang, H. (2025) · Reproductive Sciences · doi:10.1007/s43032-025-01953-0
Effect of short duration vitamin E supplementation on some reproductive hormones in infertile women
Assi, M. A., Shamran, S. G., Mahdi, K. A., & Al-fahham, A. A. (2025) · Polski Merkuriusz Lekarski · doi:10.36740/merkur202505101
Zhou, J., Zuo, W., Tan, Y., Wang, X., Zhu, M., & Zhang, H. (2024) · Figshare · doi:10.6084/m9.figshare.26575700
Zhou, J., Zuo, W., Tan, Y., Wang, X., Zhu, M., & Zhang, H. (2024) · Figshare · doi:10.6084/m9.figshare.26575697
SVEMI: An Innovative Method for PCOS Detection Using an Adapted Ensemble Machine Learning Approach
Roy, D., Ghosh, P., & Das, S. (2026) · Lecture notes in networks and systems · doi:10.1007/978-981-95-3671-9_21
Singnale, P., Sasmal, D., Chukkala, S. S., Chilumula, M., Raghavendra, P., Singh, S. P., Mummadi, M. K., & Gondru, R. (2026) · Cureus · doi:10.7759/cureus.106497
Rojo-Fleming, C. C., Berardino, C. D., Peserico, A., Canciello, A., Rapini, C. C. S., Sacchetti, G., Capacchietti, G., D’Antonio, V., Angelino, D., Serafini, M., et al. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1840637
- Authors
- Tefagh, G., Payab, M., Qorbani, M., Sharifi, F., Sharifi, Y., Ebrahimnegad Shirvani, M. S., Pourghazi, F., Atlasi, R., Shadman, Z., Rezaei, N., Mohammadi-Vajari, E., Larijani, B., & Ebrahimpur, M.
- Affiliations
- Imam Khomeini Hospital (IR)
- Endocrinology and Metabolism Clinical Sciences Institute (IR)
- Alborz University of Medical Sciences (IR)
- Endocrinology and Metabolism Population Sciences Institute (IR)
- Tehran University of Medical Sciences (IR)
- Hamedan University of Medical Sciences (IR)
- Corresponding author
- Payab, Moloud
- Ebrahimpur, Mahbube
- ORCID
- Venue
- Scientific Reports
- Published
- 2022-04-06
- Volume
- 12
- Issue
- 1
- Pages
- 5770-5770
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC8985066
- OpenAlex
- W4223554722
- Cited by
- 102
- References
- 34
- Citations by year
- 2026: 7 · 2025: 14 · 2024: 10 · 2023: 65 · 2022: 5 · 2020: 1
- FWCI
- 3.82
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Tehran University of Medical Sciences and Health Services
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- vitamin E supplementation, polycystic ovary syndrome, cardiometabolic risk factors, insulin resistance, HOMA-IR, lipid profile, triglycerides, LDL cholesterol, waist circumference, inflammatory markers, oxidative stress, luteinizing hormone, testosterone, follicle-stimulating hormone, progesterone, hormone function
- MeSH terms
- Cardiometabolic Risk Factors, Female, Humans, Insulin Resistance, Polycystic Ovary Syndrome, Vitamin E, Biomarkers, Oxidative Stress, Dietary Supplements
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
