Inter-organ cross-talk in metabolic syndrome

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Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

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The hormone resistin links obesity to diabetes

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Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010.

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Growth hormone resistance induced by amino acid deprivation in fao cells is independent of FGF21

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Integration of Dynamical Network Biomarkers, Control Theory and Drosophila Model Identifies Vasa/DDX4 as the Potential Therapeutic Targets for Metabolic Syndrome

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Lipid-lowering effects of bile Arisaema polysaccharides on high-fat diet-induced hyperlipidemia: An integrated analysis of metabolomics, lipidomics and microbiome

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Elimination of hepatocyte‐derived DPP4 downregulates cardiac immune‐ and collagen‐related genes but does not alter cardiac function in aged male mice

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Lung–brain ‘cross-talk’: systemic propagation of cytokines in the ARDS via the bloodstream using a blood transfusion model does not influence cerebral inflammatory response in pigs

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The RGD region of bone sialoprotein affects metabolic activity in mice

Nagasaki, K., Nagasaki, A., Taylor, J., Kear, B. D., Ma, Y., Somerman, M. J., & Gavrilova, O. (2023) · Frontiers in Dental Medicine · doi:10.3389/fdmed.2023.1124084 · Cited by 2

Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarctionPreprint

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Symphonies of metabolomics

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A small molecule PTER-selective inhibitor reduces food intake and body weight

Fu, S., Wang, L., Li, V. L., Lyu, X., Wei, W., Shi, X., Deng, S., Barber, J. L., Tahir, U. A., Adams, C., et al. (2026) · doi:10.64898/2026.01.26.701829 · Cited by 2

Beneficial effects of aerobic exercises on multiple myeloma: Mechanisms and clinical observations

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Autophagy and Intracellular Membrane Dynamics in Aging and Age-Related Diseases

Minami, S., Nakamura, S., & Yoshimori, T. (2025) · Learning materials in biosciences · doi:10.1007/978-3-031-88121-3_7 · Cited by 1

Standing at the crossroads: How does amino acids function in the crosstalk between pancreas and the kidney under exposure to per- and polyfluoroalkyl substances?

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Ret finger protein deficiency attenuates adipogenesis in male mice with high fat diet-induced obesity

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The Impact of Maternal High‐Fat Diet on Stem Cell Programming and Disease Susceptibility in Offspring

Gao, J., Tian, Q., LI, S.-H., Zheng, L., & Zhou, Y. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70303 · Cited by 1

Bidirectional Mendelian Randomization and Multi-Omics Uncover Causal Serum Metabolites and Neuro-Related Mechanistic Pathways in Acute Myeloid Leukemia

Ye, H., Liu, Y., Tang, J., & Li, X. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311307 · Cited by 1

Surface decoration of bacteria generates robust living therapeutics for improved ulcerative colitis therapy

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The Prickly Solution to Metabolic Syndrome: A Multitarget View on the Opuntia ficus-indica Fruit Phytocomplex

Russo, C., Surdo, S., Valle, M. S., & Malaguarnera, L. (2026) · Nutrients · doi:10.3390/nu18071157 · Cited by 1

Loss of FoxO in skeletal muscle leads to disrupted muscle metabolism and exacerbates starvation-induced hepatic steatosis

Oyabu, M., Sakaue, M., Kubo, A., Yoshioka, K., Kawaguchi, R., Yamamoto, H., Kinjo, Y., Kwon, J., Nishi, H., Yamanaka, D., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2600036123 · Cited by 2

A network analysis of whole-body [18F]FDG PET/CT reveals glycaemia-associated reorganization of systemic metabolic coordination

Guan, Z., Tao, X., Qu, J., Wang, H., Sun, Q., Xiao, Y., Li, Z., Ma, N., Lin, X., Wen, G., et al. (2026) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-026-07894-3 · Cited by 1

Pomegranate for Diabetes and its’ Complications Amelioration

Stefanou, V. (2022) · International Journal of Pharmaceutical and Bio-Medical Science · doi:10.47191/ijpbms/v2-i8-03 · Cited by 1

Sensory Property and Phenolic Profile of Aronia Juice

Huang, R. N., & Xu, C. (2023) · Reference series in phytochemistry · doi:10.1007/978-3-031-04195-2_73-1 · Cited by 2

Sensory Property and Phenolic Profile of Aronia Juice

Huang, R. N., & Xu, C. (2024) · Reference series in phytochemistry · doi:10.1007/978-3-031-38663-3_73 · Cited by 1

Carbohydrate and protein metabolism

Nishimura, T., & Yoshinari, Y. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95424-2.00011-x · Cited by 1

Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism

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Does the RGD region of certain proteins affect metabolic activity?

Nagasaki, K., Gavrilova, O., Hajishengallis, G., & Somerman, M. J. (2022) · Frontiers in Dental Medicine · doi:10.3389/fdmed.2022.974862 · Cited by 1

Impact of Bmal1 rescue and time-restricted feeding on liver and muscle proteomes during the active phase in micePreprint

Smith, J. G., Molendijk, J., Blazev, R., Chen, W. H., Zhang, Q., Litwin, C., Greco, C. M., Sassone‐Corsi, P., Muñoz‐Cánoves, P., Parker, B. L., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.12.544652 · Cited by 1

Spalt-related is an integrated stress response-activated inhibitor of mTORC1-mediated growthPreprint

Deniz, O., Liu, Y., Kirkinen, T., Kokki, K., Clavell-Revelles, P., Mattila, J., & Hietakangas, V. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.19.677425 · Cited by 1

The bandwidth of preventive cardiology continues to increase: Meeting the challenge head on

Toth, P. P. (2020) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2020.100132

Analytical and clinical comparison between two different chemiluminescent enzyme immunoassays for the measurement of C-peptide in serum

Caviglia, G. P., Rosso, C., Armandi, A., Ribaldone, D. G., Pellicano, R., & Bugianesi, E. (2021) · Minerva Biotechnology and Biomolecular Research · doi:10.23736/s2724-542x.20.02710-x

Working together

Odongo, R., & Çakır, T. (2021) · eLife · doi:10.7554/elife.69863

Exploring regulatory network of metabolism through liver research

Awazawa, M. (2021) · Diabetology International · doi:10.1007/s13340-021-00536-z

The role of liver fat in cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body compositionPreprint

van der Meer, D., Gurholt, T. P., Sønderby, I. E., Shadrin, A. A., Hindley, G., Rahman, Z., de Lange, A. G., Frei, O., Leinhard, O. D., Linge, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.24.481887

Peer Review #1 of "Lung–brain ‘cross-talk’: systemic propagation of cytokines in the ARDS via the bloodstream using a blood transfusion model does not influence cerebral inflammatory response in pigs (v0.1)"

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Peer Review #2 of "Lung–brain ‘cross-talk’: systemic propagation of cytokines in the ARDS via the bloodstream using a blood transfusion model does not influence cerebral inflammatory response in pigs (v0.1)"

(2022) · PeerJ · doi:10.7287/peerj.13024v0.1/reviews/2

Peer Review #2 of "Lung–brain ‘cross-talk’: systemic propagation of cytokines in the ARDS via the bloodstream using a blood transfusion model does not influence cerebral inflammatory response in pigs (v0.2)"

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Impact of gut-derived metabollites on substrate metabolism and metabolic health

Gonzalez Hernandez Manuel, A. (2020) · Research Publications (Maastricht University) · doi:10.26481/dis.20201027mgh

Diabetes Gestacional

Paneque, A. A. E., Ortiz, M. G. C., Maldonado, E. A. D., Matute, S. G. U., Martínez, C. E. C., & Llumiquinga, P. M. Q. (2022) · doi:10.58594/dzdk6465

Editorial: The regulatory role of metabolic organ-secreted factors in the development of cardiovascular diseases

You, M., Ruan, C., Yang, Q., Hobkirk, J., & Gao, P. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1246912

Bioenergetic and redox signaling in hepatic steatosis models: Integrative analysis of nutritional, hormonal, and inflammatory stimuli

Kakimoto, P. A. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.46.2021.tde-10082023-115406

Altered Adipocyte Cell Size Distribution Prior to Weight Loss in the R6/2 Model of Huntington’s Disease

Dickson, E., Fryklund, C., Soylu-Kucharz, R., Sjögren, M., Stenkula, K. G., & Björkqvist, M. (2023) · Journal of Huntington s Disease · doi:10.3233/jhd-230587

Loss of CTRP10 results in female obesity with preserved metabolic healthPreprint

Chen, F., Sarver, D. C., Saqib, M., Vélez, L. M., Aja, S. M., Seldin, M. M., & Wong, G. W. (2024) · eLife · doi:10.7554/elife.93373.1

Alterações do metabolismo lipídico no fígado durante a termogênese adaptativa

Vieira, V. A. (2023) · doi:10.11606/d.17.2023.tde-06022024-102543

Additional file 2 of Metabolic syndrome and the plasma proteome: from association to causation

Elhadad, M. A., Wilson, R., Zaghlool, S. B., Huth, C., Gieger, C., Grallert, H., Graumann, J., Rathmann, W., Köenig, W., Sinner, M. F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14634053

Novel Strategies for Optimization of the Pre-transplant Donor Lung

Hozain, A. E., & Jablonski, R. P. (2024) · Current Pulmonology Reports · doi:10.1007/s13665-024-00348-x

A cell culture-based method for interrogating muscle to liver communication via secreted proteins

Tsialtas, I., & Koronowski, K. B. (2024) · Methods in cell biology · doi:10.1016/bs.mcb.2024.08.005

Effects of yoga on metabolic syndrome

Chatterjee, S., Pramanik, P., & Basu‐Ray, I. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99645-7.00031-7 · Cited by 1

Does the Combination of Metabolic Syndrome and Low Fat‐Free Mass Shorten an Individual's Disability‐Free Life? A 12‐Year Prospective Cohort Study of the Korean Genome and Epidemiology Study (KoGES)

Shin, J. H., & Yoon, J. Y. (2024) · Public Health Nursing · doi:10.1111/phn.13494

DUPLA CARGA: ABORDAGEM DE PRECISÃO EM PACIENTES PORTADORES DE HIPERTENSÃO ARTERIAL E OBESIDADE – O QUE SABEMOS EM 2024?

Júnior, E. L., Université de Liège Belgique.Liége, B., & Academia Paranaense de Medicina. Paraná, P. (2024) · Revista Brasileira de Hipertensão · doi:10.47870/1519-7522/20243104145-7

Effects of therapeutic factors on brown adipose tissue in order to correct obesity

Kurmaev, D. P., Bulgakova, S. V., Treneva, E. V., & Merzlova, P. Y. (2025) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-228-8-7-27

Loss of CTRP10 results in female obesity with preserved metabolic healthPreprint

Chen, F., Sarver, D. C., Saqib, M., Vélez, L. M., Aja, S. M., Seldin, M. M., & Wong, G. W. (2025) · eLife · doi:10.7554/elife.93373.2

Chronic Liver Disease Primarily Presenting with Motor Weakness by Intractable Hypokalemia with Combined Respiratory Alkalosis and Chronic Diarrhea: A Case Report

Beck, N. S., Jeong, Y.-O., Lee, K., Jun, E.-M., Im, J.-I., & Hong, S.-Y. (2025) · Case Reports in Gastroenterology · doi:10.1159/000544099

Role of Hepatic Lipoprotein Receptor-related Protein 1 (LRP-1) on Amyloid Beta Pathology in a Mouse Model of Amyloidosis

Panchal, U. R. (2025) · Chapman University Digital Commons (Chapman University) · doi:10.36837/chapman.000657

The Crosstalk Between Non-Coding RNAs and Lipid Metabolism in Chronic Disease Progression

Zayani, Z., Matinahmadi, A., Tavakolpournegari, A., Moosavi, S. S., & Bidooki, S. H. (2025) · Lipidology · doi:10.3390/lipidology2040019

Additional file 1 of Metabolic syndrome and the plasma proteome: from association to causation

Elhadad, M. A., Wilson, R., Zaghlool, S. B., Huth, C., Gieger, C., Grallert, H., Graumann, J., Rathmann, W., Koenig, W., Sinner, M. F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14634050

Eicosanoids and Bioactive Lipids in Modulation of Inflammation in Metabolic Disorders

Maji, S., Mishra, S. S., & Smaoui, S. (2026) · Springer eBooks · doi:10.1007/978-3-032-11752-6_9

Label-Free Target Discovery Strategy for Natural Active Products

Shan, L., Chen, Y., Cao, X., Jin, X., & Liu, B. (2026) · Biomolecules · doi:10.3390/biom16040507

Rôle des vésicules extracellulaires dans les altérations de l'homéostasie musculaire au cours du développement de l'insulino-résistance

Reininger, L. (2020) · theses.fr (ABES) · doi:10.70675/b01e109dz43b1z4f4czabaez3285404d1642

Inter-organ communication in physiology and pathophysiology : a role for the ChREBP-FGF21 axis?

Carbinatti, T. (2024) · theses.fr (ABES) · doi:10.70675/5d147ab4zad37z4f6bzac51z32a08efeaa51

From Single-target to System Remodeling：Combination Therapeutic Strategies for Metabolic Diseases

Xie, Z., & Li, J. (2026) · 中国科学基金 · doi:10.3724/bnsfc-2025-0006

Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications

Mourya, A. K., Jain, R., & Kumar, A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-36641-3.00001-2

Liver-originated selective autophagy of BTD by alectinib underlies concurrent hepatotoxicity and dermatotoxicity

Huang, X., Zhang, S., Yuan, M., Zhou, Y., Chen, X., Xia, B., Xu, Z., Yang, X., Yang, B., He, Q., et al. (2026) · Autophagy · doi:10.1080/15548627.2026.2672162

Toward relational biosecurity: understanding AI-enabled biology as a connected system

Holko, M. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1856819

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesityPreprint

Su, Y.-Y., Bundalian, L. T., Chen, Y.-C., Gjermeni, E., Gille, B., Richter, S., Jasaszwili, M., Palma-Vera, S., Hoffmann, A., Ghosh, A., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.20.726524

Metabolic characteristics and factors associated with prediabetes in Chinese adults based on real-world health examination data: a cross-sectional study

Sun, X., Zhou, J., Chen, Z., Xin, Z., Ren, J., Zheng, Y. N., Wang, J., Zhang, J. Q., Zhang, Y., Liu, L., et al. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1850839

Leptin in Dairy Cows: Metabolic Adaptation, Reproductive Function, and Health Applications

Martínez-Barbitta, M., Biagini, A., Costanzi, E., Guelfi, G., Maranesi, M., García‐Díez, J., Saraiva, C. M. T., Karama, M., El-Ashram, S. A., Al-Olayan, E. M., et al. (2026) · Life · doi:10.3390/life16060987

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

Smimmo, M., Casale, V., Bianca, R. D. D. V., Vellecco, V., & Bucci, M. (2026) · British Journal of Pharmacology · doi:10.1111/bph.70557

Spalt-related is an inhibitor of mTORC1-mediated growth activated by the integrated stress response

Deniz, O., Liu, Y., Kirkinen, T., Kokki, K., Gaertner, K., Clavell-Revelles, P., Mattila, J., & Hietakangas, V. (2026) · The EMBO Journal · doi:10.1038/s44318-026-00858-1 · Cited by 1

Metabolic Regulation by Adipokines, Hepatokines, and Myokines

Stefan, N., White, M. F., & Häring, H. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-11985-9.00012-3

Nutrition as a regulator of tissue crosstalk: Implications for metabolic health and disease

Mısırlıoğlu, P. E. (2026) · Clinical Nutrition Open Science · doi:10.1016/j.nutos.2026.100709

Mitochondrial Dysfunction as a Central Hub of Aging: From Molecular Cascades to Inter-Organ Communication Networks

Han, C., Zhang, Z., & Song, Y. (2026) · Gerontology · doi:10.1159/000553430

Liver-to-vessel communication: A new mechanism linking MASLD to cardiovascular disease

Wang, B. (2026) · Molecular Therapy · doi:10.1016/j.ymthe.2026.08.012

Effect of chilacayote (Cucurbita ficifolia Bouché) flour consumption in a metabolic syndrome model on Wistar rats

López, J. R. R., Aquino-Bolaños, E. N., Meza, S. H., Chávez‐Servia, J. L., Carrillo-Rodríguez, J. C., Santos-Basurto, M. A., & Alba-Jiménez, J. E. (2026) · BIOtecnia · doi:10.18633/biotecnia.v28.2995

Preclinical evidence and multi-omics insights into the protective effects of epigallocatechin-3-gallate against high-fat diet-induced adverse health outcomes

Liu, M., Jiang, J., Wang, Z., Ma, X., Zeng, J., & Tang, J. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158750

Homeostatic Correction During Severe Physiologic Stress: A Phase-Specific Model for GC–GRα-Coordinated Organism-Wide Adaptation

Meduri, G. U., & Torres, A. (2026) · Medical Sciences · doi:10.3390/medsci14060638

Integrated Multi-Tissue Omics Identifies Acylcarnitine Accumulation as Shared Metabolic Marker of Diabetic Microangiopathy With Cross-Organ Validation

Liu, Q., Liu, Y., Yang, X., Liu, T., Zhao, Y., Xia, J., Fu, X., 姚牧笛, Wang, Y., Jiang, Q., et al. (2026) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.67.11.31

Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk

Palanivel, M., Narayana, J. K., & Chotirmall, S. H. (2026) · Comprehensive physiology · doi:10.1002/cph4.70269

Integrated targeted metabolomics and complementary [α-15N] glutamine tracing reveal glutamine metabolic remodeling associated with RA-ILD

Jiang, L., Shen, L., Fang, S., Sun, F., Xin, G.-Z., Liu, L., & Zheng, J. (2026) · Analytica Chimica Acta · doi:10.1016/j.aca.2026.346299

Network Biology: Current Status, Applications, Challenges, and Future Prospects

Li, X., Zhang, L., Ding, Y., Li, K., Chang, S., Pei, L., Li, Z., & Chen, Z. (2026) · MedComm · doi:10.1002/mco2.71065

Genomic profiling of estrogen-related receptor identifies adult adipocyte-specific targets in Drosophila

Yin, J., Rusch, D. B., Bhatta, J. S., Merritt, D. M., & Weaver, L. N. (2026) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkag293

Beyond Numerical Thresholds: A Systems-Level Perspective on Dysglycaemia and the Liver–Brain Axis in Brain Injury

Canepa, M. E., Panfoli, I., Mangini, S., Calandrino, A., Vinci, F., Malova, M., Striano, P., Gagliardi, L., & Ramenghi, L. A. (2026) · Antioxidants · doi:10.3390/antiox15111401

Inter‐organ communication: a gatekeeper for metabolic health

Castillo‐Armengol, J., Fajas, L., & Lopez‐Mejia, I. C. (2019) · The EMBO Reports · doi:10.15252/embr.201947903 · Cited by 178

Inter-organ communication involved in metabolic regulation at the whole-body level

Katagiri, H. (2023) · Inflammation and Regeneration · doi:10.1186/s41232-023-00306-1 · Cited by 24

Roles of the interorgan neuronal network in the development of metabolic syndrome

Uno, K. (2016) · Diabetology International · doi:10.1007/s13340-016-0277-8 · Cited by 4

Lipid metabolites as metabolic messengers in inter-organ communication

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