Mitophagy in human health, ageing and disease

Hallmarks of aging: An expanding universe

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023) · Cell · doi:10.1016/j.cell.2022.11.001 · Cited by 6,549

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

Sies, H., & Jones, D. P. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0230-3 · Cited by 5,335

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

Eslam, M., Newsome, P. N., Sarin, S. K., Anstee, Q. M., Targher, G., Romero-Gomez, M., Zelber-Sagi, S., Wai-Sun Wong, V., Dufour, J.-F., Schattenberg, J. M., et al. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.03.039 · Cited by 4,472

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Lazarou, M., Sliter, D. A., Kane, L. A., Sarraf, S. A., Wang, C., Burman, J. L., Sideris, D. P., Fogel, A. I., & Youle, R. J. (2015) · Nature · doi:10.1038/nature14893 · Cited by 2,774

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

Egan, B., & Zierath, J. R. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2012.12.012 · Cited by 2,084

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

Fang, E. F., Hou, Y., Palikaras, K., Adriaanse, B. A., Kerr, J. S., Yang, B., Lautrup, S., Hasan-Olive, M. M., Caponio, D., Dan, X., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-018-0332-9 · Cited by 1,740

Defective repair replication of DNA in xeroderma pigmentosum

CLEAVER, J. E. (1968) · Nature · doi:10.1038/218652a0 · Cited by 1,729

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Cantó, C., & Auwerx, J. (2009) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328328d0a4 · Cited by 1,624

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

Palikaras, K., Lionaki, E., & Tavernarakis, N. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0176-2 · Cited by 1,556

Vitisin B rejuvenates senescence via WBP2NL regulation

Yoon, J. H., Lee, Y. H., Oh, S., Lee, K. S., Park, J. H., Lee, Y. J., So, B., Kim, D., Kim, M., Kwon, H. W., et al. (2026) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2026.112159 · Cited by 2

Insulin-like growth factor 2 mRNA-binding Protein 2 regulates PINK1 expression through m6A pathway to promote mitophagy in BMSCs alleviating postmenopausal osteoporosis

Ji, Y., Cui, Y., Li, L., Cao, T., Liu, H., & Ji, Y. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.01.038 · Cited by 1

Interplay between Peripheral and Central Nervous System Myeloid Cells during Aging: Impact for Lade-Life Depression and Alzheimer’s Disease

de Miranda, A. S., Vieira, É. L. M., Teixeira, A. L., & Bauer, M. E. (2026) · NeuroImmunoModulation · doi:10.1159/000550781 · Cited by 1

Mitophagy in pancreatic cancer: mechanistic insights and implications for novel therapeutic strategies

Wang, Z., Lyu, Z., Palmen, R., Bao, Q., Popp, F., Dong, Q., Bruns, C. J., & Zhao, Y. (2026) · Cell Death Discovery · doi:10.1038/s41420-026-02948-9 · Cited by 1

MOTS-c attenuates cardiac dysfunction following high altitude exposure by promoting mitophagy

Feng, Z., Yuan, X., Lou, J., Li, H., Zhang, Z., Li, M., Zhu, Q., Cui, Y., Li, J., Gao, F., et al. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.01.064 · Cited by 1

Nanomedicine as core enablers: Mechanisms of mitophagy and theranostic strategies in ischemia-reperfusion injury

Zhou, S., Wang, X., Zhu, J., Zheng, J., Song, X., Huang, B., & Chen, Y. (2026) · Nano Today · doi:10.1016/j.nantod.2026.103005 · Cited by 1

Ginsenoside Rb1 Inhibits Phosphorylation of Cx43 and Promotes Mitophagy To Attenuate Mouse Cerebral Ischemia/Reperfusion Injury

Chen, W., Ye, G., Chen, P., Wang, H., Li, Z., Liu, X., Zhang, G., & Feng, J. (2026) · Neurochemical Research · doi:10.1007/s11064-026-04687-w · Cited by 1

Vav-iCre-Mediated Deletion of TFAM Is Not Recoverable and Is Consistent with Embryonic Lethality

Ghosh, R. B., Shakur, E., & Yousefzadeh, M. J. (2026) · Genes · doi:10.3390/genes17030255 · Cited by 1

Molecular Pathophysiology of Ischemic Stroke and Mesenchymal Stem Cell Based Therapeutic Strategies for Neural Tissue Regeneration: A Pre-clinical and Clinical Perspective

Ishaque, A., Qazi, R., Salim, A., Malick, T. S., & Asif, Z. (2026) · Stem Cell Reviews and Reports · doi:10.1007/s12015-026-11071-2 · Cited by 1

Resistance training for the prevention and management of sarcopenia in older adults: Mechanisms, efficacy, and future applications

Lan, L., Liu, C., & Wu, W. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113085 · Cited by 2

Nicotine-induced mitophagy in bronchial epithelial cells and MYST1 downregulation in cigarette smoke–exposed lungs: potential mechanisms of COPD progression

Liu, K., Xu, D., Zhao, J., Mo, R., Lin, M., He, C., Lin, Q., Xie, T., Li, Q., & Ding, Y. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-11574-8 · Cited by 1

Mitophagy enhancement delays mouse mesenchymal stem cell senescence by attenuating the senescence-associated secretory phenotype

Sun, Y., Fu, X., Li, Y., Peng, M., & Yang, L. (2026) · Molecular Biology of the Cell · doi:10.1091/mbc.e25-11-0560 · Cited by 1

Asprosin Protects H9C2 Cells From Ferroptosis Following Hypoxia/Reoxygenation by Promoting Mitophagy

Wang, X., Zhang, X., Tang, H., Su, X., Ding, S., Li, X., & Li, B. (2026) · Cardiovascular Therapeutics · doi:10.1155/cdr/8401037 · Cited by 1

Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans

Valenzuela-Villatoro, M., Ruiz, P. D. L. C., Guerrero‐Gómez, D., Gómez‐Orte, E., Schiavi, A., Maglioni, S., Montero, M., Fonteríz, R. I., Casas-Martinez, J. C., Briand, N. E., et al. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104115 · Cited by 2

Gentiopicroside activates PINK1-dependent mitophagy to inhibit ferroptosis and promote flap survival

Pan, H., Wang, K., Wang, A., Deng, J., Yang, J., Tan, P., Song, W., Xu, P., Chen, G., Bian, Z., et al. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.121504 · Cited by 1

Nanomaterials regulate cellular functions and influence cell fate through mitophagy

Wang, Y., Li, D., Ai, Z., Tian, Y., & Zhang, C. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114816 · Cited by 1

2-Methoxystypandrone from Polygonum cuspidatum Rejuvenates Senescence by Reducing Mitochondrial ROS

Yoon, J. H., Kim, Y. H., Kim, M., Jeong, E. Y., Lee, Y. H., Park, J. H., Lee, Y. J., Lee, S. H., Kim, H. Y., Kang, H. M., et al. (2026) · Antioxidants · doi:10.3390/antiox15030357 · Cited by 1

S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis

Zheng, H., Tian, S., Wu, L., Jia, G., Xiao, Y., Yu, X., Zuo, Q., Zhou, R., Min, J., Wu, Q., et al. (2026) · The Journal of Headache and Pain · doi:10.1186/s10194-026-02328-9 · Cited by 1

The interplay between mitophagy and ferroptosis in Alzheimer’s disease: Mechanisms and therapeutic implications

Liu, A., Xing, L., Li, J., Yao, M., Song, J., Guo, W., Duan, P., & Li, H. (2026) · Journal of Alzheimer s Disease · doi:10.1177/13872877261420211 · Cited by 1

The Estrogen–Mitochondria Axis in Bipolar Disorder: From Fluctuating Hormones to Failing Bioenergetics

Zachos, K. A., Behravan, K., Demyati, J., & Andreazza, A. C. (2026) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2026.100723 · Cited by 1

PAK4 functions as an immune suppressor by reprogramming the phosphatidylcholine metabolism of CD8 + T cells within the glioblastoma tumor microenvironment

Yao, L., Gao, H., Su, Z., Zhao, G., Tang, L., Feng, S., Ma, Y., Zhang, X., Feng, M., Qian, J., et al. (2026) · Oncogene · doi:10.1038/s41388-026-03734-8 · Cited by 1

Revitalizing mitochondrial quality control: targeting mitochondria-derived vesicles in Parkinson’s disease

Ameer, J. M., Alexander, S. M., Navya, K., Shenoi, R. A., & Chandra, G. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.117935 · Cited by 1

Mitochondrial Regulation of Periodontal Ligament Stem Cell Fate and Function

Zhao, Z., Liu, S., Liu, N., & Liu, Q. (2026) · Stem Cell Reviews and Reports · doi:10.1007/s12015-026-11148-y · Cited by 1

Mitoredox shifts in mitochondrial dysfunction

Moos, W. H., Faller, D. V., Glavas, I. P., Kanara, I., Kodukula, K., Pernokas, J., Pernokas, M., Pinkert, C. A., Powers, W. R., Sampani, K., et al. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.05.307 · Cited by 2

Skeletal Muscle Redox Signaling in Health and Disease: From Molecular Mechanisms to Therapeutic Exercise Strategies

Yun, H. R., Singh, M. K., Han, S., Ranbhise, J. S., Seo, H., Kim, S. S., & Kang, I. (2026) · Antioxidants · doi:10.3390/antiox15060678 · Cited by 2

MMP7-Triggered mitophagy by regulating parkin-mediated ubiquitination of VDAC1 confers anoikis resistance in the epithelium of hyperplastic prostate

Zhou, Y., Li, Y., Liu, H., Zhang, J., Qiu, J., Du, L., Lai, H., Chen, P., Guo, Y., Luo, Y., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08867-y · Cited by 1

PLD3-mediated Mitophagy Attenuates Neuronal Ferroptosis and Promotes Functional Recovery after Spinal Cord Injury

Ding, X., Dai, B., Peng, J., Sun, K., Lan, S., Yang, L., Ye, C., Pan, S., Wang, C., Liang, X. L., et al. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05986-7 · Cited by 1

Caffeine, skeletal muscle signalling, and exercise adaptation: a narrative review separating acute ergogenic effects from chronic remodelling

Liu, Z., Zheng, H., Deng, H., Wang, M., Du, W., Chen, M., Zhang, Z., & Wu, B. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1875283 · Cited by 1

Mitochondrial disease: mechanisms, signalling, and therapeutic opportunities

Corrà, S., Young, L., Moore, A. L., & Viscomi, C. F. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.06.013 · Cited by 1

Pterostilbene mitigates intervertebral disc degeneration via dual regulation of mitophagy and NLRP3 ubiquitination to inhibit nucleus pulposus cell pyroptosis

Zhang, Y., Liu, S., Dong, S., Song, G., Wang, K., Zhou, Z., Yang, G., Yang, X., Peng, S., Zhang, Y., et al. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158459 · Cited by 1

Extracellular Mitochondria Mediate Endothelial Injury After Traumatic Brain Injury

Tang, L., Liu, Y., Pang, K., Li, Y., Zhang, Y., Lu, X., Zhang, X., Zhao, P., Zhou, Z., Zhang, H., et al. (2026) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.126.323502 · Cited by 1

Desmoglein-2 deficiency drives mitochondrial morphological remodeling in cardiomyocytes

Gonçalves, A., Chen, E. Z., Rastegarpouyani, H., Fernandes, A. A., Alves, I. N., Sequeira, V., Kwon, C., Chelko, S. P., & Landim-Vieira, M. (2026) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00368.2026 · Cited by 1

DRP1-mediated mitophagy facilitates oral squamous cell carcinoma tumor cell survival under glucose restriction

Yu, Q., Xiao, T., Li, Z., Jing, Y., Song, Y., Zhang, X., Huang, X., & Ni, Y. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.06.051 · Cited by 1

Restoration of macrophage mitochondrial dynamics and trafficking with enzymatic magnesium-manganese layered double hydroxide for osteoporotic therapy

Mao, W., Wang, K., Mao, J., Xu, Z., Pan, C., Li, D., Liu, T., Chen, H., Wang, H., Huang, C., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04761-z · Cited by 2

Mitigating Environmental Pollutant-Induced Premature Ovarian Insufficiency by Rationally Designed Ultrasmall Gold Nanoparticles via Dual Regulation of ROS and Mitophagy

Xue, L., Cao, K., Du, M., Jiang, Y., Xia, D., Gao, L., Ji, C., & Gao, X. (2026) · Environment & Health · doi:10.1021/envhealth.6c00186 · Cited by 1

A dual-engineered chondrocyte-targeting tetrahedral DNA-based nanoparticle for improved delivery of metformin and alleviation in osteoarthritis

Han, Q., Han, Q., Deng, H., Alifu, A., Li, J., Chen, Z., Deng, L., Cai, X., Chen, Y., & Lin, Y. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124425 · Cited by 1

Mechanisms by Which Plant Extracts Ameliorate Bovine Mastitis Through the Regulation of Mitochondrial Function: A Review

Li, Z., Song, J., Ao, C., Wang, L., Zhang, T., Zhao, Y., Guo, C., Zhong, H., & Liu, J. (2026) · Cells · doi:10.3390/cells15131222 · Cited by 1

Microglial Mitochondrial Dysfunction: The Storm Center of Post‐Stroke Neuroinflammation

Fan, R., Wang, C., Lin, Z. B., Chen, S., Pan, C., Nie, H., Qin, C., Wu, X., & Tang, Z. (2026) · CNS Neuroscience & Therapeutics · doi:10.1002/cns.71060 · Cited by 1

The Zuo Jin Wan Formula Reverses Cisplatin Resistance in Gastric Cancer by Inhibiting the Mitochondrial Translocation of Dynamin‐Related Protein 1 and Its Mediated Mitochondrial Fission and Mitophagy

Zhao, Z., Yuan, M., Yang, X., Ji, Q., Liu, G., Tang, Q., & Sun, J. (2026) · Cancer Medicine · doi:10.1002/cam4.72131 · Cited by 1

Exosome-mediated delivery of 3-n-butylphthalide rescues microglial energy crisis and ameliorates neuroinflammation in ischemic stroke

Wang, B., Xi, M., Lin, K., 郭青龙, & Wang, Y. (2026) · Neurotherapeutics · doi:10.1016/j.neurot.2026.e00977 · Cited by 1

Redox-sensitive coordination of mitochondrial quality control: Integrating ROS, NAD+, and Ca2+ signaling in disease

Marcondes‐de‐Castro, I. A., Sales, T. A., Marinho, T. D. S., Águila, M. B., & Mandarim‐de‐Lacerda, C. A. (2026) · Life Sciences · doi:10.1016/j.lfs.2026.124642 · Cited by 1

HMOX1-mediated ferroptosis participates in gangrenous mastitis in dairy goats

Tan, X., Fu, M., Li, H., Gao, J., Wang, X., Liu, N., Liu, Y., Zhang, W., Zhuang, S., An, X., et al. (2026) · The Veterinary Journal · doi:10.1016/j.tvjl.2026.106849 · Cited by 1

Integrative Analyses of Mitophagy-Related Genes and Mechanisms Associated with Type 2 Diabetes in Muscle Tissue

Mao, W., Zong, G., Gao, Y., Qu, S., & Cheng, X. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46090619 · Cited by 1

Cynaropicrin Suppresses Cell Proliferation by Inducing Mitophagy through p38 MAPK-Mediated Mitochondrial ROS Generation in Human Hepatocellular Carcinoma Cells

Kim, M. Y., Hwangbo, H., Ji, S. Y., Kim, D. H., Park, S., Hong, S. H., Kim, G., Bang, E., & Choi, Y. H. (2025) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2501.01025 · Cited by 1

PPTC7 acts as an essential co-factor of the SCF FBXL4 ubiquitin ligase complex to restrict BNIP3/BNIP3L-dependent mitophagyPreprint

Xu, X., Chen, Y., Li, Y., Zhao, S., & Wang, C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.20.599818 · Cited by 1

Mitochondria-Lysosome Crosstalk Shapes Metabolic Transition in Neonatal EnterocytesPreprint

Herranz, G., Alonso-Larre, D., González, T., Akintche, L., Ramos-Manzano, A., Iborra-Pernichi, M., de la Esperanza, M. V., Díaz-Díaz, C., Ganley, I. G., Boya, P., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.09.674148 · Cited by 1

Mitochondrial defects in sporadic inclusion body myositis—causes and consequences

Iu, E. C. Y., So, H., & Chan, C. B. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1403463

Fluorescence Microscopy and Immunoblotting for Mitophagy in Budding Yeast

Nakayama, Y., & Okamoto, K. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-4067-8_1

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body MyositisPreprint

Kleefeld, F., Cross, E., Lagos, D., Schoser, B. G. H., Hentschel, A., Ruck, T., Nelke, C., Walli, S., Hahn, K., Hathazi, D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.08.05.606624

The effect of cinnamic acid derivative on the activity of mitochondrial enzymes in brain tissue under conditions of experimental Parkinson's disease

Pozdnyakov, D. I. (2024) · Science and Innovations in Medicine · doi:10.35693/sim630264

The pathophysiology of sepsis and autophagy

Watanabe, E., & Honda, G. (2024) · Japanese Journal of Thrombosis and Hemostasis · doi:10.2491/jjsth.35.702

Chuangxiong-Danggui Herb Pair Alleviated Cognitive Deficits of App/Ps1 Mice by Promoting Fundc1-Mediated MitophagyPreprint

Pu, K., Yang, S., Sheng, R., Chen, J., Zhong, Z., & Xu, S. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5076382

Age-related neuroinflammation and exacerbated immune responses in PINK1 and PARK2 knockout mice with experimental autoimmune encephalomyelitisPreprint

Cossu, D., Noda, S., Sato, S., Yokoyama, K., Tomizawa, Y., Vascellari, S., Sechi, L. A., & Hattori, N. (2025) · Research Square · doi:10.21203/rs.3.rs-6240835/v1

Engineering ATP Import in Yeast Uncovers a Synthetic Route to Extend Cellular LifespanPreprint

Oz, N., Su, H., Sari, V., Patnaik, P. K., Hameed, R., Song, J. H., Prosser, D. C., Labunskyy, V. M., Gladyshev, V. N., Hao, N., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.14.648769 · Cited by 1

Determination of ADP / ATP translocase isoform ratios in malignancy and cellular senescence

Liblova, Z., Maurencova, D., Šalovská, B., Kratky, M., Mráček, T., Korandová, Z., Pecinová, A., Vašicová, P., Rysanek, D., Anděra, L., et al. (2025) · Molecular Oncology · doi:10.1002/1878-0261.70039 · Cited by 1

A multilayer network approach elucidates time- and tissue-specific developmental and aging processesPreprint

Lombardo, S. D., Rendeiro, A. F., & Menche, J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.02.651926

Mitochondrial Health in Cardiometabolic Diseases and Aging: Clinical Applications of Therapeutic Fasting and Natural Supplements

Tripathi, A. P., Verma, M., Tripathi, M., & Singh, B. K. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1009875

Revealing the landscape of targeting mitochondrial functions and behaviors to overcome cancer chemoresistance

Zhang, H., Wang, S., Wu, P., Hu, Z., Chen, Y., Guan, Y., & Pang, J. (2025) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2025.02.007

Introduction to mitochondrial toxicity: Form, function, and signaling

Fink, D. M., Hanson, R. L., Moncada-Restrepo, M., & Chambers, J. W. (2025) · Advances in neurotoxicology · doi:10.1016/bs.ant.2025.05.002

Dimethyl fumarate inhibits keratinocyte hyperproliferation and ameliorates psoriasis via directly targeting ribosomal protein S6 kinase A1

Zhang, S., Liu, D., Wen, F., Lyu, H., Zhang, J., Wang, N., Liu, Y., Zhang, X., Ma, A., & Wang, J. (2026) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2026.101692

Aloe-emodin inhibits cell proliferation by inducing AMPK-mediated mitochondrial autophagy in the human hepatocellular carcinoma cell line Hep3B

Choi, Y. H. (2025) · Molecular & Cellular Toxicology · doi:10.1007/s13273-025-00553-y

MITOCHONDRIAL THERAPIES IN AGING AND AGE-RELATED DISEASES

Borysova, O. (2025) · Anti-Aging Eastern Europe · doi:10.56543/aaeeu.2025.4.2.02

Research on bionic mechanism based adaptive collaborative self-healing method

Sun, W., Xu, L., Li, T., & Hu, A. (2025) · International Symposium on Computer Technology and Information Science (ISCTIS) · doi:10.1109/isctis65944.2025.11065611

RICTOR regulates an interspecies crosstalk that influences longevity through a novel methionine cycle-mitophagy axisPreprint

Motwani, S., Bhandari, S., Chitkara, S., Ujjainiya, R., Sengupta, S., & Mukhopadhyay, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.11.664440

Thioredoxin-1 inhibits granulosa cell ferroptosis to rescue ovarian aging through mitophagy-dependent activation of BNIP3LPreprint

Yang, W., Zhang, X., Xu, R., Huang, Z., Ma, Y., Yang, J., Zheng, L., Ma, G., Xu, J., Qiao, Y., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.12.664497

Mitophagy related gene signature for prognosis and therapeutic evaluation in KIRC

Duan, D., Guo, Y., Li, J., Li, Z., Xu, G., Niu, Y., & Zhao, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-10798-1

Drug-induced metabolic remodeling of immune cell repertoire generates an effective broad-range antimicrobial effectPreprint

Prusty, B. K., Hollmann, C., Park, E. C., Liu, Z., Nourollahi, F., Nikolayshvili, G., Dietz, J., Basens, E. E., Vora, M., Waghmare, T. S., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7077811/v1

Mammalian cells evacuate and shelter mitochondrial DNA from destruction following hypoxia response-induced mitophagyPreprint

Kamegai, R., Uenosono, A., Ikeda, F., Ohta, K., & Yanagitani, K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.01.667885

Mitophagy Activation by N-Acetylcysteine Protects against Mic60 Deficiency-Induced Auditory Neuropathy

Sun, Y., Liu, C., Liang, Y., Lv, A., Nie, W., Bao, S., Li, X., Zhou, J., Tong, W., Tao, Y., et al. (2025) · Neuroscience Bulletin · doi:10.1007/s12264-025-01485-2

Assessment of Mitochondrial Network Remodeling and Colocalization with Lysosomes in Primary Astrocyte Cultures from 5xFAD Mice

Okhalnikov, A. D., Anastasia, M., Ermoshina, A. A., & Maria, G. B. (2025) · International Conference Neurotechnologies and Neurointerfaces (CNN) · doi:10.1109/cnn67635.2025.11177480

Prognostic genes related to mitochondrial dynamics and mitophagy in diffuse large B-cell lymphoma are identified and validated using an integrated analysis of bulk and single-cell RNA sequencing

Chen, Q., Chen, M., Wang, J., Dong, J., Yang, A., Zhu, X., Lin, Q., Huang, J., Lai, G., Zheng, M., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1686948

Impact of different exercise modalities on mitophagy in human skeletal muscle

Muñoz-Medina, C., Carriel-Nesvara, A., Botella, J., & Castro-Sepulveda, M. (2025) · International review of cytology · doi:10.1016/bs.ircmb.2025.10.005

A Reversible Mitochondrial ROS Probe for Monitoring Mitophagy Dynamics: Development and Application of MitoFlarePreprint

Hou, S., Yan, X., Li, X., Ju, J., Shan, Z. J., & Bi, L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.18.689025

Living therapeutics: Colorectal related diseases precision therapy with engineered organisms

Huang, J., Lan, Y., Chen, L., Guan, X., Liang, R., Liang, J., Gao, M., Gan, J., Guo, Y., & Zhang, S. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.112151

Imbalance in MICOS Proteins in Rat Liver Mitochondria in an Induced Hyperthyroidism Model

Venediktova, N. I., Solomadin, I., Nikiforova, A. B., & Bessonova, T. A. (2025) · Cells · doi:10.3390/cells14231877

Dietary lipid content modifies wah-1/AIFM1-associated phenotypes via LRK-1 and DRP-1 expression in C. elegans

Mondal, M., Scifo, E., Ciliberti, R. E., Wischhof, L., Abbariki, T. N., Jackson, J., Menegatou, I.-M., Zeisler-Diehl, V. V., Riemer, J., Jussila, B., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66900-8 · Cited by 1

From autophagy to mitophagy: Quality control mechanisms in skeletal muscle

Antuña, E., Menéndez-Coto, N., Fernández-Guisasola, P., & Coto‐Montes, A. M. (2025) · International review of cytology · doi:10.1016/bs.ircmb.2025.11.006

RAB7B as a Potential Therapeutic Target in Liver Cirrhosis: Insights from Protein Expression and Bioinformatics Analyses

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