The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Nanoparticles: pharmacological and toxicological significance
Open accessAbstract
Nanoparticles are tiny materials (<1000 nm in size) that have specific physicochemical properties different to bulk materials of the same composition and such properties make them very attractive for commercial and medical development. However, nanoparticles can act on living cells at the nanolevel resulting not only in biologically desirable, but also in undesirable effects. In contrast to many efforts aimed at exploiting desirable properties of nanoparticles for medicine, there are limited attempts to evaluate potentially undesirable effects of these particles when administered intentionally for medical purposes. Therefore, there is a pressing need for careful consideration of benefits and side effects of the use of nanoparticles in medicine. This review article aims at providing a balanced update of these exciting pharmacological and potentially toxicological developments. The classes of nanoparticles, the current status of nanoparticle use in pharmacology and therapeutics, the demonstrated and potential toxicity of nanoparticles will be discussed. British Journal of Pharmacology (2007) 150, 552–558. doi:10.1038/sj.bjp.0707130
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Cites
Passage of inhaled particles into the blood circulation in humans
Nemmar, A., Hoet, P. H. M., Vanquickenborne, B., Dinsdale, D., Thomeer, M., Hoylaerts, M. F., Vanbilloen, H., Mortelmans, L., & Nemery, B. (2002) · Circulation · doi:10.1161/hc0402.104118 · Cited by 1,719
Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., & Alexander, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj130 · Cited by 1,167
Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency
Jani, P., Halbert, G. W., Langridge, J., & Florence, A. T. (1990) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1990.tb07033.x · Cited by 920
Engineering of nanoemulsions for drug delivery
Sarker, D. (2005) · Current Drug Delivery · doi:10.2174/156720105774370267 · Cited by 268 · cited 1×
“Like liposomes, emulsions have been used for improving the efficacy and safety of diverse compounds (Sarker, 2005).”
Background
Cited by
Vanlalveni, C., Lallianrawna, S., Biswas, A., Selvaraj, M., Changmai, B., & Rokhum, S. L. (2021) · RSC Advances · doi:10.1039/d0ra09941d · Cited by 804
Shvedova, A. A., Kisin, E., Murray, A. R., Johnson, V. J., Gorelik, O., Arepalli, S., Hubbs, A. F., Mercer, R. R., Keohavong, P., Sussman, N., et al. (2008) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.90287.2008 · Cited by 641
Recent advances of cocktail chemotherapy by combination drug delivery systems
Hu, Q., Sun, W., Wang, C., & Gu, Z. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.10.022 · Cited by 625
Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma
Song, Y., Li, X., & Du, X. (2009) · European Respiratory Journal · doi:10.1183/09031936.00178308 · Cited by 448
Nanotechnology in agro-food: From field to plate
Dasgupta, N., Ranjan, S., Mundekkad, D., Ramalingam, C., Shanker, R., & Kumar, A. (2015) · Food Research International · doi:10.1016/j.foodres.2015.01.005 · Cited by 437
Metadata
- Authors
- Medina, C., Santos‐Martinez, M. J., Radomski, A., Corrigan, O. I., & Radomski, M. W.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 2007-03
- Volume
- 150
- Issue
- 5
- Pages
- 552-558
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W2107854895
- Cited by
- 738
- References
- 4
- FWCI
- 19.28
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Medina, C., Santos‐Martinez, M. J., Radomski, A., Corrigan, O. I., & Radomski, M. W. (2007). Nanoparticles: pharmacological and toxicological significance. British Journal of Pharmacology. https://doi.org/10.1038/sj.bjp.0707130
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
