Differential regulation of interleukin-10 production by genetic and environmental factors – a twin study

IL-10 inhibits cytokine production by activated macrophages

Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M., & O’Garra, A. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.11.3815 · Cited by 2,888 · see citing works

AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER

Turner, D. M., Williams, D. M., Sankaran, D., Lazarus, M. N., Sinnott, P. J., & Hutchinson, I. V. (1997) · European Journal of Immunogenetics · doi:10.1111/j.1365-2370.1997.tb00001.x · Cited by 1,706 · see citing works

Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

Rousset, F., Garcia, E., Defrance, T., Péronne, C., Vezzio, N., Hsu, D. H., Kastelein, R., Moore, K. W., & Banchereau, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.5.1890 · Cited by 1,238 · see citing works

Human Genetics. Problems and Approaches.

(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-1-163_3 · Cited by 991 · see citing works

Cytokine gene polymorphism in human disease: on-line databases

Bidwell, J. L., Keen, L. J., Gallagher, G. E., Kimberly, R. P., Huizinga, T. W. J., McDermott, M., Oksenberg, J. R., McNicholl, J., Pociot, F., Hardt, C., et al. (1999) · Genes and Immunity · doi:10.1038/sj.gene.6363645 · Cited by 810 · see citing works

Genetic control of the circulating concentration of transforming growth factor type beta1

Grainger, D. J. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.1.93 · Cited by 754 · see citing works

Arthritis of the finger joints: A comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging

Backhaus, M., Kamradt, T., SANDROCK, D., Loreck, D., Fritz, J., Wolf, K.-J., Raber, H., Hamm, B., Burmester, G. R., & BOLLOW, M. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199906)42:6 · Cited by 642 · see citing works

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus.

Llorente, L., Zou, W., Lévy, Y., Richaud‐Patín, Y., Wijdenes, J., Alcocer-Varela, J. C., Morel-Fourrier, B., Brouet, J. C., Alarcón-Segovia, D., Galanaud, P., et al. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.181.3.839 · Cited by 540 · see citing works

Properties and Functions of Interleukin-10

Mosman, T. R. (1994) · Advances in immunology · doi:10.1016/s0065-2776(08)60449-6 · Cited by 495 · see citing works

Interleukin 10 secretion in relation to human IL-10 locus haplotypes

Eskdale, J., Gallagher, G. E., Verweij, C. L., Keijsers, V., Westendorp, R. G. J., & Huizinga, T. W. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9465 · Cited by 466 · see citing works

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

Zhang, P., Behre, G., Pan, J., Iwama, A., Wara-aswapati, N., Radomska, H. S., Auron, P. E., Tenen, D. G., & Sun, Z. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.15.8705 · Cited by 459 · see citing works

Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa

Edwards-Smith, C. J., Jonsson, J. R., Purdie, D. M., Bansal, A. S., Shorthouse, C., & Powell, E. E. (1999) · Hepatology · doi:10.1002/hep.510300207 · Cited by 403 · see citing works

Predominant role of tumor necrosis factor- alpha in human monocyte IL-10 synthesis.

Wanidworanun, C., & Strober, W. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.151.12.6853 · Cited by 389 · see citing works

Novel Single Nucleotide Polymorphisms in the Distal IL-10 Promoter Affect IL-10 Production and Enhance the Risk of Systemic Lupus Erythematosus

Gibson, A., Edberg, J. C., Wu, J., Westendorp, R. G. J., Huizinga, T. W. J., & Kimberly, R. P. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.6.3915 · Cited by 384 · see citing works

Human Genetics

Vogel, F., & Motulsky, A. G. (1997) · Springer eBooks · doi:10.1007/978-3-662-03356-2 · Cited by 278 · see citing works

Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers

Takanashi, S., Hasegawa, Y., Kanehira, Y., Yamamoto, K., Fujimoto, K., Satoh, K., & Okamura, K. (1999) · European Respiratory Journal · doi:10.1034/j.1399-3003.1999.14b12.x · Cited by 229 · see citing works

T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection

Murray, P. J., Wang, L., Onufryk, C., Tepper, R. I., & Young, R. A. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.1.315 · Cited by 225 · see citing works

Microsatellite alleles and single nucleotide polymorphisms (SNP) combine to form four major haplotype families at the human interleukin-10 (IL-10) locus

Eskdale, J., Keijsers, V., Huizinga, T. W. J., & Gallagher, G. E. (1999) · Genes and Immunity · doi:10.1038/sj.gene.6363656 · Cited by 217 · see citing works

Isolation of the Human Interleukin 10 Promoter. Characterization of the Promoter Activity in Burkitt's Lymphoma Cell Lines

Kube, D., Platzer, C., von Knethen, A., Straub, H., Bohlen, H., Hafner, M., & Tesch, H. (1995) · Cytokine · doi:10.1006/cyto.1995.1001 · Cited by 216 · see citing works

Genetic influence on cytokine production in meningococcal disease

Westendorp, R., Langermans, J. A. M., Huizinga, T. W. J., Verweij, C. L., & Sturk, A. (1997) · The Lancet · doi:10.1016/s0140-6736(05)63910-4 · Cited by 179 · see citing works

Association between polymorphisms at the human IL‐10 locus and systemic lupus erythematosus

Eskdale, J., Wordsworth, P., Bowman, S., Field, M., & Gallagher, G. E. (1997) · Tissue Antigens · doi:10.1111/j.1399-0039.1997.tb02812.x · Cited by 175 · see citing works

Activity loss and the onset of depressive symptoms: Do some activities matter more than others?

Katz, P., & Yelin, E. (2001) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200105)44:5 · Cited by 175 · see citing works

Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers

Takanashi, S., Hasegawa, Y., Kanehira, Y., et al. (1999) · European Respiratory Journal · doi:10.1183/09031936.99.14230999 · Cited by 156 · see citing works

A polymorphic dinucleotide repeat in the human IL-10 promoter

Eskdale, J., & Gallagher, G. E. (1995) · Immunogenetics · doi:10.1007/bf00179416 · Cited by 151 · see citing works

High Levels Of Interleukin-10 During The Initial Phase Of Fulminant Meningococcal Septic Shock

Derkx, B., Marchant, A., Goldman, M., Bijlmer, R. P. G. M., & van Deventer, S. J. H. (1995) · The Journal of Infectious Diseases · doi:10.1093/infdis/171.1.229 · Cited by 136 · see citing works

Determination of tumour necrosis factor-α and interleukin-10 production in a whole blood stimulation system: assessment of laboratory error and individual variation

van der Linden, M. W., Huizinga, T. W. J., Stoeken, D.-J., Sturk, A., & Westendorp, R. G. J. (1998) · Journal of Immunological Methods · doi:10.1016/s0022-1759(98)00108-2 · Cited by 130 · see citing works

B-Cell-Derived IL-10: Production and Function

Burdin, N., Rousset, F., & Banchereau, J. (1997) · Methods · doi:10.1006/meth.1996.0393 · Cited by 115 · see citing works

A second polymorphic dinucleotide repeat in the 5′ flanking region of the human IL10 gene

Eskdale, J., Kube, D., & Gallagher, G. E. (1996) · Immunogenetics · doi:10.1007/s002510050174 · Cited by 106 · see citing works

The Ets family of proteins: weak modulators of gene expression in quest for transcriptional partners.

Crépieux, P., Coll, J., & Stéhelin, D. (1994) · PubMed · Cited by 103 · see citing works

New polymorphisms in the IL-10 promoter region

D’Alfonso, S., Rampi, M., Rolando, V., Giordano, M., & Momigliano‐Richiardi, P. (2000) · Genes and Immunity · doi:10.1038/sj.gene.6363666 · Cited by 102 · see citing works

Production of Proinflammatory Cytokines and Cytokines Involved in the TH1/TH2 Balance Is Modulated by Pentoxifylline

Bienvenu, J., Doche, C., Gutowski, M. C., Lenoble, M., Lepape, A., & Perdrix, J.-P. (1995) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199500252-00017 · Cited by 93 · see citing works

Autocrine Induction of the Human Pro-IL-1β Gene Promoter by IL-1β in Monocytes

Toda, Y., Tsukada, J., Misago, M., Kominato, Y., Auron, P. E., & Tanaka, Y. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1984 · Cited by 65 · see citing works

High Levels of Interleukin 10 and Tumor Necrosis Factor in Cerebrospinal Fluid During the Onset of Bacterial Meningitis

van Furth, A. M., Seijmonsbergen, E. M., Langermans, J. A. M., Groeneveld, P. H. P., de Bel, C. E., & van Furth, R. (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/21.1.220 · Cited by 59 · see citing works

Cross-sectional study on cytokine polymorphisms, cytokine production after T-cell stimulation and clinical parameters in a random sample of a German population

Nieters, A., Brems, S., & Becker, N. (2001) · Human Genetics · doi:10.1007/s004390100464 · Cited by 56 · see citing works

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1

Borràs, F. E., Lloberas, J., Maki, R. A., & Celada, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.41.24385 · Cited by 40 · see citing works

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone modulation of cytokine release in U937 human macrophages

Rioux, N., & Castonguay, A. (2001) · Cancer Immunology Immunotherapy · doi:10.1007/s002620000157 · Cited by 19 · see citing works

The Hematopoietic Transcription Factor PU.1 Represses Gelatinase A Transcription in Glomerular Mesangial Cells

Harendza, S., Lovett, D. H., & Stahl, R. A. K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001322200 · Cited by 17 · see citing works

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

Villagra, A., Cheng, F., Wang, H.-W., Suarez, I., Glozak, M., Maurin, M., Nguyen, D., Wright, K. L., Atadja, P. W., Bhalla, K., et al. (2009) · Nature Immunology · doi:10.1038/ni.1673 · Cited by 455 · see citing works

Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level

Kurreeman, F. A. S., Schonkeren, J. J. M., Heijmans, B. T., Toes, R. E. M., & Huizinga, T. W. J. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh187 · Cited by 262 · see citing works

Cell type-specific regulation of IL-10 expression in inflammation and disease

Hedrich, C. M., & Bream, J. H. (2010) · Immunologic Research · doi:10.1007/s12026-009-8150-5 · Cited by 220 · see citing works

Heritability estimates of innate immunity: an extended twin study

de Craen, A. J. M., Danielle Posthuma, B., Remarque, E. J., van den Biggelaar, A. H. J., Westendorp, R. G. J., & Boomsma, D. I. (2005) · Genes and Immunity · doi:10.1038/sj.gene.6364162 · Cited by 187 · see citing works

Pneumococcal Septic Shock Is Associated with the Interleukin-10–1082 Gene Promoter Polymorphism

Schaaf, B., Boehmke, F., Esnaashari, H., Seitzer, U., Kothe, H., Maass, M., Zabel, P., & Dalhoff, K. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200210-1164oc · Cited by 179 · see citing works

SNP-SNP interactions in breast cancer susceptibility

Onay, V., Briollais, L., Knight, J. A., Shi, E., Wang, Y., Wells, S., Li, H., Rajendram, I., Andrulis, I. L., & Özçelik, H. (2006) · BMC Cancer · doi:10.1186/1471-2407-6-114 · Cited by 170 · see citing works

IL-12 and IL-10 polymorphisms and their effects on cytokine production

Yılmaz, V., Yentur, S. P., & Saruhan‐Direskeneli, G. (2005) · Cytokine · doi:10.1016/j.cyto.2005.01.006 · Cited by 165 · see citing works

Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-β, FAS, and mannose-binding protein C gene polymorphisms in Australian women: Risk of preterm birth

Annells, M. F., Hart, P. H., Mullighan, C. G., Heatley, S. L., Robinson, J. S., Bardy, P., & McDonald, H. M. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.04.021 · Cited by 163 · see citing works

Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection

Knapp, S., Hennig, B. J., Frodsham, A. J., Zhang, L., Hellier, S. C., Wright, M., Goldin, R. D., Hill, A. V. S., Thomas, H. C., & Thursz, M. R. (2003) · Immunogenetics · doi:10.1007/s00251-003-0594-5 · Cited by 161 · see citing works

Interleukin-1 is the initiator of Fallopian tube destruction during Chlamydia trachomatis infection

Hvid, M., Baczynska, A., Deleuran, B. W., Fedder, J., Knudsen, H. J., Christiansen, G., & Birkelund, S. (2007) · Cellular Microbiology · doi:10.1111/j.1462-5822.2007.00996.x · Cited by 159 · see citing works

Why interleukin-10 supplementation does not work in Crohn’s disease patients

Marlow, G. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i25.3931 · Cited by 148 · see citing works

The Leiden Early Arthritis Clinic.

van Aken, J., van Bilsen, J. H. M., Allaart, C. F., Huizinga, T. W. J., & Breedveld, F. C. (2003) · PubMed · Cited by 147 · see citing works

Cytokine gene polymorphisms, cancer susceptibility, and prognosis.

Howell, W. M., & Rose-Zerilli, M. J. J. (2007) · Journal of NutriLife · doi:10.1093/jn/137.1.194s · Cited by 136 · see citing works

The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: A role for interleukin-10

Gotsch, F., Romero, R. J., Kusanovic, J. P., Erez, O., Espinoza, J., Kim, C. J., Vaisbuch, E., Than, N. G., Mazaki‐Tovi, S., Chaiworapongsa, T., et al. (2008) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050802127349 · Cited by 138 · see citing works

Identification of genes modulated in multiple myeloma using genetically identical twin samples

Munshi, N. C., Hideshima, T., Carrasco, D. E., Shammas, M. A., Auclair, D., Davies, F. E., Mitsiades, N., Mitsiades, C. S., Kim, R. S., Li, C., et al. (2003) · Blood · doi:10.1182/blood-2003-02-0402 · Cited by 137 · see citing works

Host genetic determinants in hepatitis C virus infection

Yee, L. J. (2004) · Genes and Immunity · doi:10.1038/sj.gene.6364090 · Cited by 122 · see citing works

Polymorphisms of some cytokines and chronic hepatitis Band C virus infection

Gao, Q., Liu, D., Zhang, S., Jia, M., Wang, L.-M., Wu, L., Wang, S., & Tong, L.-X. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.5610 · Cited by 119 · see citing works

Functionally relevant variations of the interleukin‐10 gene associated with antineutrophil cytoplasmic antibody–negative Churg‐Strauss syndrome, but not with Wegener's granulomatosis

Wieczorek, S., Hellmich, B., Arning, L., Moosig, F., Lamprecht, P., Gross, W. L., & Epplen, J. T. (2008) · Arthritis & Rheumatism · doi:10.1002/art.23496 · Cited by 113 · see citing works

Influence of Promoter Variants of Interleukin‐10, Interleukin‐9, and Tumor Necrosis Factor–α Genes on Respiratory Syncytial Virus Bronchiolitis

Hoebee, B., Bont, L., Rietveld, E., van Oosten, M., Hodemaekers, H. M., Nagelkerke, N. J. D., Neijens, H. J., Kimpen, J. L. L., & Kimman, T. G. (2004) · The Journal of Infectious Diseases · doi:10.1086/380908 · Cited by 110 · see citing works

Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression

Hofmann, S. R., Schwarz, T., Möller, J. C., Morbach, H., Schnabel, A., Rösen‐Wolff, A., Girschick, H. J., & Hedrich, C. M. (2011) · Clinical Immunology · doi:10.1016/j.clim.2011.08.012 · Cited by 106 · see citing works

The broad effects of the functional IL-10 promoter-592 polymorphism: modulation of IL-10, TIMP-3, and OPG expression and their association with periodontal disease outcome

Claudino, M., Trombone, A. P. F., Cardoso, C. R. D. B., Ferreira, S. B., Martins, W., de Assis, G. F., Santos, C. F., Trevilatto, P. C., Campanelli, A. P., Silva, J. S., et al. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0308184 · Cited by 102 · see citing works

Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome

Mälarstig, A., Eriksson, P. O., Hamsten, A., Lindahl, B., Wallentin, L. C., & Siegbahn, A. G. (2007) · Heart · doi:10.1136/hrt.2007.119271 · Cited by 100 · see citing works

Interleukin-10 polymorphism in position -1082 and acute respiratory distress syndrome

Gong, M. N., Thompson, B., Williams, P. L., Zhou, W., Wang, M. Z., Pothier, L. J., & Christiani, D. C. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00046405 · Cited by 100 · see citing works

Mosaics of gene variations in the Interleukin-10 gene promoter affect interleukin-10 production depending on the stimulation used

Mörmann, M., Rieth, H., Hua, T.-D., Assohou, C., Roupelieva, M., Hu, S. L., Kremsner, P. G., Luty, A. J. F., & Kube, D. (2004) · Genes and Immunity · doi:10.1038/sj.gene.6364073 · Cited by 98 · see citing works

TNF‐α‐, TNF‐β‐, IL‐6‐, and IL‐10‐promoter polymorphisms in patients with chronic obstructive pulmonary disease

Seifart, C., Dempfle, A., Plagens, A., Seifart, U., Clostermann, U., Müller, B., Vogelmeier, C. F., & von Wichert, P. (2005) · Tissue Antigens · doi:10.1111/j.1399-0039.2005.00343.x · Cited by 97 · see citing works

Cytokine responses and sudden infant death syndrome: genetic, developmental, and environmental risk factors

Blackwell, C. C., Moscovis, S. M., Gordon, A. E., Madani, O. M. A., Hall, S. T., Gleeson, M., Scott, R. J., Roberts-Thomson, J., Weir, D. M., & Busuttil, A. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0505253 · Cited by 92 · see citing works

TNF‐α, TNF‐β, IL‐6, and IL‐10 Polymorphisms in Patients with Lung Cancer

Seifart, C., Plagens, A., Dempfle, A., Clostermann, U., Vogelmeier, C. F., von Wichert, P., & Seifart, U. (2005) · Disease Markers · doi:10.1155/2005/707131 · Cited by 91 · see citing works

Non-HLA immunogenetic polymorphisms and the risk of complications after allogeneic hemopoietic stem-cell transplantation

Mullighan, C. G., Heatley, S. L., Doherty, K., Szabó, F., Grigg, A., Hughes, T. P., Schwarer, A. P., Szer, J., Tait, B. D., To, B., et al. (2004) · Transplantation · doi:10.1097/01.tp.0000111769.45088.a2 · Cited by 88 · see citing works

Giant cell arteritis and polymyalgia rheumatica: Role of cytokines in the pathogenesis and implications for treatment

Martínez-Taboada, V. M., Álvarez, L., Ruiz‐Soto, M., Marín-Vidalled, M. J., & López‐Hoyos, M. (2008) · Cytokine · doi:10.1016/j.cyto.2008.09.004 · Cited by 87 · see citing works

Gender Susceptibility to Chronic Hepatitis C Virus Infection Associated with Interleukin 10 Promoter Polymorphism

Paladino, N., Fainboim, H. A., Theiler, G., Schroder, T., Muñoz, A., Flores, A. C., Galdame, O., & Fainboim, L. (2006) · Journal of Virology · doi:10.1128/jvi.00339-06 · Cited by 86 · see citing works

Nutritional properties of small ruminant food products and their role on human health

Albenzio, M., Santillo, A., Avondo, M., Nudda, A., Chessa, S., Pirisi, A., & Banni, S. (2015) · Small Ruminant Research · doi:10.1016/j.smallrumres.2015.12.016 · Cited by 82 · see citing works

Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance

Oleksyk, T. K., Thio, C. L., Truelove, A. L., Goedert, J. J., Donfield, S. M., Kirk, G. D., Thomas, D. L., O’Brien, S. J., & Smith, M. W. (2005) · Genes and Immunity · doi:10.1038/sj.gene.6364188 · Cited by 82 · see citing works

Interleukin-10 Polymorphisms, Cancer Susceptibility and Prognosis

Howell, W. M., & Rose-Zerilli, M. J. J. (2005) · Familial Cancer · doi:10.1007/s10689-005-0072-3 · Cited by 82 · see citing works

The interleukin‐10 promoter haplotype ATA is a putative risk factor for aggressive periodontitis

Reichert, S., Machulla, H. K. G., Klapproth, J., Zimmermann, U., Reichert, Y., Gläser, C., Schaller, H. ‐., Stein, J. M., & Schulz, S. (2007) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2007.00992.x · Cited by 75 · see citing works

A Functional Polymorphism in the IL - 10 Promoter Influences the Response After Vaccination With HBsAg and Hepatitis A *

Höhler, T., Reuss, E., Freitag, C. M., & Schneider, P. M. (2005) · Hepatology · doi:10.1002/hep.20740 · Cited by 74 · see citing works

Single nucleotide polymorphisms (SNPs) of pro-inflammatory/anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype

Tuttolomondo, A., Raimondo, D. D., Forte, G. I., Casuccio, A., Vaccarino, L., Scola, L., Pecoraro, R., Serio, A., Clemente, G., Arnao, V., et al. (2012) · Cytokine · doi:10.1016/j.cyto.2012.02.012 · Cited by 72 · see citing works

Association of the –2849 interleukin‐10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis

Lard, L. R., van Gaalen, F. A., Schonkeren, J. J. M., Pieterman, E. J., Stoeken‐Rijsbergen, G., Vos, K., Nelissen, R. G. H. H., Westendorp, R. G. J., Hoeben, R. C., Breedveld, F. C., et al. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11160 · Cited by 69 · see citing works

Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO)

Hofmann, S. R., Roesen-Wolff, A., Hahn, G., & Hedrich, C. M. (2012) · International Journal of Rheumatology · doi:10.1155/2012/310206 · Cited by 70 · see citing works

Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function

van Exel, E. R., de Craen, A. J. M., Remarque, E. J., Gussekloo, J., Houx, P. J., Wiel, A. B. D., Frölich, M. A., Macfarlane, P. W., Blauw, G. J., & Westendorp, R. G. J. (2003) · Neurology · doi:10.1212/01.wnl.0000098877.07653.7c · Cited by 69 · see citing works

Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma

Hohaus, S., Giachelia, M., Febo, A. D., Martini, M., Massini, G., Vannata, B., D’Alò, F., Guidi, F., Greco, M., Pierconti, F., et al. (2007) · Annals of Oncology · doi:10.1093/annonc/mdm132 · Cited by 68 · see citing works

Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for −819C/T in leprosy susceptibility

Latini, A. C. P., de Souza, V. N. B., Cardoso, C. C., Dias‐Baptista, I. M. F., Parelli, F. P. C., Venturini, J., Vilani‐Moreno, F. R., Pacheco, A. G., & Moraes, M. O. (2008) · Genes and Immunity · doi:10.1038/gene.2008.97 · Cited by 67 · see citing works

Sudden infant death syndrome, infection and inflammatory responses

VEGE, P. (2004) · FEMS Immunology & Medical Microbiology · doi:10.1016/j.femsim.2004.06.015 · Cited by 66 · see citing works

Genetic and ethnic risk factors associated with drug hypersensitivity

Kim, S., Ye, Y., Palikhe, N. S., Kim, J., & Park, H. (2010) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e32833b1eb3 · Cited by 65 · see citing works

IL-10 gene polymorphisms in infectious disease and SIDS

Opdal, S. H. (2004) · FEMS Immunology & Medical Microbiology · doi:10.1016/j.femsim.2004.06.006 · Cited by 63 · see citing works

Cytokine Genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and Childhood-Onset Mood Disorders

Misener, V. L., Gomez, L., Wigg, K., Luca, P., King, N. A., Kiss, É., Daróczi, G., Kapornai, K., Tamás, Z., Mayer, L., et al. (2008) · Neuropsychobiology · doi:10.1159/000159775 · Cited by 61 · see citing works

Gene variants predisposing to SIDS: current knowledge

Opdal, S. H., & Rognum, T. O. (2010) · Forensic Science Medicine and Pathology · doi:10.1007/s12024-010-9182-9 · Cited by 57 · see citing works

IL‐10 promoter and IL4‐Rα gene SNPs are associated with immediate β‐lactam allergy in atopic women

Guglielmi, L., Fontaine, C., Gougat, C., Avinens, O., Eliaou, J., Guglielmi, P., & Demoly, P. M. (2006) · Allergy · doi:10.1111/j.1398-9995.2006.01067.x · Cited by 57 · see citing works

Association of Serum Cytokine Levels With Treatment Response to Pegylated Interferon and Ribavirin Therapy in Genotype 1 Chronic Hepatitis C Patients

Yoneda, S., Umemura, T., Katsuyama, Y., Kamijo, A., Joshita, S., Komatsu, M., Ichijo, T., Matsumoto, A., Yoshizawa, K., Ôta, M., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiq165 · Cited by 56 · see citing works

Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10

Wang, H., Cheng, F., Woan, K. V., Sahakian, E., Merino, O., Rock-Klotz, J. A., Vicente-Suarez, I., Pinilla-Ibarz, J. A., Wright, K. L., Seto, E., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1001101 · Cited by 54 · see citing works

Is interleukin-10 gene polymorphism a predictive marker in HCV infection?

Świątek, B. (2012) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2012.01.005 · Cited by 54 · see citing works

Influence of genetic polymorphisms on interleukin-10 mRNA expression and psoriasis susceptibility

Kingo, K., Rätsep, R., Kõks, S., Karelson, M., Silm, H., & Vasar, E. (2004) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2004.10.002 · Cited by 51 · see citing works

Differences in protein fraction from goat and cow milk and their role on cytokine production in children with cow's milk protein allergy

Albenzio, M., Campanozzi, A., D’Apolito, M., Santillo, A., Pettoello‐Mantovani, M., & Sevi, A. (2012) · Small Ruminant Research · doi:10.1016/j.smallrumres.2012.02.018 · Cited by 51 · see citing works

Association Between IL-10 Gene Promoter Polymorphisms (-592 A/C, -819 T/C, -1082 A/G) and Susceptibility to HBV Infection in an Iranian Population

Moudi, B., Heidari, Z., Mahmoudzadeh‐Sagheb, H., Hashemi, M. M., Metanat, M., Khosravi, S., & Farrokh, P. (2016) · Hepatitis Monthly · doi:10.5812/hepatmon.32427 · Cited by 51 · see citing works

Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease

Combarros, O., van Duijn, C. M., Hammond, N., Belbin, O., Vásquez, A. A., Cortina‐Borja, M., Lehmann, M. G., Aulchenko, Y. S., Schuur, M., Kölsch, H., et al. (2009) · Journal of Neuroinflammation · doi:10.1186/1742-2094-6-22 · Cited by 51 · see citing works

Reduced mortality and CD4 cell loss among carriers of the interleukin-10 −1082G allele in a Zimbabwean cohort of HIV-1-infected adults

Erikstrup, C., Kallestrup, P., Zinyama-Gutsire, R. B. L., Gomo, E., Butterworth, A. E., Pedersen, B. K., Ostrowski, S. R., Gerstoft, J., & Ullum, H. (2007) · AIDS · doi:10.1097/qad.0b013e3282f153ed · Cited by 50 · see citing works

Polymorphisms in interleukin‐10 and interleukin‐28 B genes in E gyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to pegylated interferon/ribavirin‐therapy

Shaker, O. G., & Sadik, N. A. H. (2012) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2012.07273.x · Cited by 47 · see citing works

DNA polymorphisms and response to treatment in patients with chronic hepatitis C: Results from the HALT-C trial

Morgan, T. R. M., Lambrecht, R. W., Bonkovsky, H. L., Chung, R. T., Naishadham, D., Sterling, R. K., Fontana, R. J., Lee, W. M., Ghany, M. G., Wright, E. C., et al. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.05.011 · Cited by 47 · see citing works

Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan

Afzal, M. S., Tahir, S., Salman, A., Baig, T. A., Shafi, T., Zaidi, N. U. S. S., & Qadri, I. (2011) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.1338 · Cited by 47 · see citing works

Smoking and Atherosclerotic Cardiovascular Disease: Part II: Role of Cigarette Smoking in Cardiovascular Disease Development

Unverdorben, M., von Holt, K., & Winkelmann, B. R. (2009) · Biomarkers in Medicine · doi:10.2217/bmm.09.51 · Cited by 47 · see citing works

Association of Apical Periodontitis with Cardiovascular Disease via Noninvasive Assessment of Endothelial Function and Subclinical Atherosclerosis

Chauhan, N., Mittal, S., Tewari, S., Sen, J., & Laller, K. S. (2019) · Journal of Endodontics · doi:10.1016/j.joen.2019.03.003 · Cited by 47 · see citing works

Endodontic Infection and Endothelial Dysfunction Are Associated with Different Mechanisms in Men and Women

Cotti, E., Zedda, A. M., Deidda, M., Piras, A., Flore, G., Ideo, F., Madeddu, C., Pau, V., & Mercuro, G. G. (2015) · Journal of Endodontics · doi:10.1016/j.joen.2015.01.037 · Cited by 46 · see citing works

Genetic variants in IL-6 and IL-10 genes and susceptibility to hepatocellular carcinoma in HCV infected patients

Sghaier, I., Mouelhi, L., Rabia, N. A., Alsaleh, B., Ghazoueni, E., Almawi, W. Y., & Loueslati, B. Y. (2016) · Cytokine · doi:10.1016/j.cyto.2016.10.004 · Cited by 44 · see citing works

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis

Cardoso, A., Castro, A. G., Martins, A. C. M., Carriche, G. M., Murigneux, V., Castro, I., Cumano, A., Vieira, P., & Saraiva, M. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00400 · Cited by 46 · see citing works

Genetic Variation in the Interleukin‐10 Gene Promoter and Risk of Coronary and Cerebrovascular Events

Trompet, S., Pons, D., de Craen, A. J. M., Slagboom, P. E., SHEPHERD, J., Blauw, G. J., Murphy, M. B., Cobbe, S. M., Bollen, E. L. E. M., Buckley, B. M., et al. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1395.018 · Cited by 46 · see citing works

Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

Briollais, L., Wang, Y., Rajendram, I., Onay, V., Shi, E., Knight, J. A., & Özçelik, H. (2007) · BMC Medicine · doi:10.1186/1741-7015-5-22 · Cited by 45 · see citing works

Interleukin‐10 promoter polymorphisms in giant cell arteritis

Boiardi, L., Casali, B., Farnetti, E., Pipitone, N., Nicoli, D., Macchioni, P., Cimino, L., Bajocchi, G., Catanoso, M., Pattacini, L., et al. (2006) · Arthritis & Rheumatism · doi:10.1002/art.22218 · Cited by 44 · see citing works

Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze

Schuurhof, A., Janssen, R., de Groot, H., Hodemaekers, H. M., de Klerk, A., Kimpen, J. L. L., & Bont, L. (2011) · Respiratory Research · doi:10.1186/1465-9921-12-121 · Cited by 44 · see citing works

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

Ranatunga, D., Hedrich, C. M., Wang, F., McVicar, D. W., Nowak, N., Joshi, T., Feigenbaum, L., Grant, L. R., Stäger, S., & Bream, J. H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904955106 · Cited by 43 · see citing works

IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin

Schippers, E. F., VANTVEER, C., VANVOORDEN, S., Martina, C. A., Huizinga, T. W. J., le Cessie, S., & VANDISSEL, J. (2005) · Cytokine · doi:10.1016/j.cyto.2004.12.005 · Cited by 43 · see citing works

Cytokine Gene Polymorphisms in Italian Preterm Infants: Association Between Interleukin-10 –1082 G/A Polymorphism and Respiratory Distress Syndrome

Capasso, M., Avvisati, R. A., Piscopo, C., Laforgia, N., Raimondi, F., Angelis, F. D., & Iolascon, A. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e318030d108 · Cited by 42 · see citing works

Sp1 binds to the G allele of the−1087 polymorphism in the IL-10 promoter and promotes IL-10 mRNA transcription and protein production

Larsson, L., Rymo, L., & Berglundh, T. (2010) · Genes and Immunity · doi:10.1038/gene.2009.103 · Cited by 41 · see citing works

Effects of Chronic Stress and Interleukin-10 Gene Polymorphisms on Antibody Response to Tetanus Vaccine in Family Caregivers of Patients with Alzheimer’s Disease

Li, J., Cowden, L. G., King, J. D., Briles, D. A., Schroeder, H. W., Stevens, A. B., Perry, R. T., Chen, Z., Simmons, M. S., Wiener, H. W., et al. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3180cc2c61 · Cited by 40 · see citing works

The Septic Shock-Associated IL-10 −1082 A > G Polymorphism Mediates Allele-Specific Transcription via Poly(ADP-Ribose) Polymerase 1 in Macrophages Engulfing Apoptotic Cells

Kang, X., Kim, H.-J., Ramírez, M., Salameh, S., & Ma, X. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903613 · Cited by 40 · see citing works

Single-nucleotide polymorphism of Toll-like receptor 4 and interleukin-10 in response to interferon-based therapy in Egyptian chronic hepatitis C patients

Sadik, N. A. H., Shaker, O. G., Ghanem, H. Z., Hassan, H. A., & Abdel‐Hamid, A. Z. (2015) · Archives of Virology · doi:10.1007/s00705-015-2493-0 · Cited by 41 · see citing works

Extended IL10 haplotypes and their association with HIV progression to AIDS

Oleksyk, T. K., Shrestha, S., Truelove, A. L., Goedert, J. J., Donfield, S. M., Phair, J., Mehta, S. H., O’Brien, S. J., & Smith, M. W. (2009) · Genes and Immunity · doi:10.1038/gene.2009.9 · Cited by 40 · see citing works

Association and interaction of the TNF‐alpha gene with other pro‐ and anti‐inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India

Kumar, R., Goswami, R., Agarwal, S., Israni, N., Singh, S. K., & Rani, R. (2007) · Tissue Antigens · doi:10.1111/j.1399-0039.2007.00817.x · Cited by 39 · see citing works

IL10 and IL12B polymorphisms each influence IL‐12p70 secretion by dendritic cells in response to LPS

Peng, J., AbuBakar, S., Richardson, M. M., Jonsson, J. R., Frazer, I. H., Nielsen, L. K., Morahan, G., & Thomas, R. (2006) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2006.01419.x · Cited by 38 · see citing works

Genetic Polymorphisms in Cytokine Genes in Colombian Patients with Ocular Toxoplasmosis

Galvis, C. A. N., de‐la‐Torre, A., Mantilla-Muriel, L. E., Beltrán, L., Elcoroaristizabal-Martín, X., McLeod, R. L., Alliey‐Rodriguez, N., Begeman, I. J., de Mesa, C. L., Gómez‐Marín, J. E., et al. (2018) · Infection and Immunity · doi:10.1128/iai.00597-17 · Cited by 39 · see citing works

TNF‐α and IL‐10 polymorphisms increase the risk to hepatocellular carcinoma in HCV infected individuals

Aroucha, D. C. B. L., do Carmo, R. F., Vasconcelos, L. R. S., de Lima, R. E., Belmont, T. F. D. M., Alvarado-Arnez, L. E., Cavalcanti, M. S. M., Muniz, M. T. C., Aroucha, M. L., de Siqueira, É. R. F., et al. (2016) · Journal of Medical Virology · doi:10.1002/jmv.24501 · Cited by 36 · see citing works

A prospective study in children with a severe form of atopic dermatitis: clinical outcome in relation to cytokine gene polymorphisms.

Kayserová, J., Sismova, K., Zentsová, I., Katina, S., Vernerová, E., Poloučková, A., Čapková, Š., Malinová, V., Striz, I., & Šedivá, A. (2012) · PubMed · Cited by 36 · see citing works

Clinical significance of interleukin-10 gene polymorphisms and plasma levels in Hodgkin lymphoma

Hohaus, S., Giachelia, M., Massini, G., Vannata, B., Criscuolo, M., Martini, M., D’Alò, F., Voso, M. T., Larocca, L. M., & Leone, G. G. M. (2009) · Leukemia Research · doi:10.1016/j.leukres.2009.01.009 · Cited by 35 · see citing works

Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans

Ayele, F. T., Doumatey, A. P., Huang, H., Zhou, J., Charles, B. A., Erdos, M. R., Adeleye, J., Balogun, W., Fasanmade, O. A., Johnson, T., et al. (2011) · Immunogenetics · doi:10.1007/s00251-011-0596-7 · Cited by 35 · see citing works

Host factors impacting the innate response in humans to the candidate adjuvants RC529 and monophosphoryl lipid A

Tiberio, L., Fletcher, L. D., Eldridge, J. H., & Duncan, D. D. (2003) · Vaccine · doi:10.1016/j.vaccine.2003.10.019 · Cited by 34 · see citing works

Regulatory polymorphisms in the IL‐10 gene promoter and HBV‐related acute liver failure in the Chinese population

Yan, Z., Tan, W., Zhao, W., Dan, Y., Wang, X., Mao, Q., Wang, Y., & Deng, G. (2009) · Journal of Viral Hepatitis · doi:10.1111/j.1365-2893.2009.01139.x · Cited by 34 · see citing works

Analysis of interleukin-10 gene polymorphisms in patients with chronic periodontitis and healthy controls

Heidari, Z., Moudi, B., Mahmoudzadeh‐Sagheb, H., & Moudi, M. (2018) · Dental Research Journal · doi:10.4103/1735-3327.223614 · Cited by 33 · see citing works

Cytokine gene polymorphisms in northern Indian women with recurrent miscarriages

Parveen, F., Shukla, A., & Agarwal, S. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.09.025 · Cited by 33 · see citing works

Cytokines and pregnancy: Potential regulation by histone deacetylases

Munro, S. K., Balakrishnan, B., Lissaman, A. C., Gujral, P., & Ponnampalam, A. P. (2021) · Molecular Reproduction and Development · doi:10.1002/mrd.23430 · Cited by 32 · see citing works

Genetic priming of a proinflammatory profile predicts low IQ in octogenarians

Krabbe, K. S., Mortensen, E. L., Avlund, K., Pilegaard, H., Christiansen, L., Pedersen, B. K., Schroll, M., Jørgensen, T., Pedersen, B. K., & Brüünsgaard, H. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.08.013 · Cited by 31 · see citing works

Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27

Hedrich, C. M., Ramakrishnan, A., Dabitao, D., Wang, F., Ranatunga, D., & Bream, J. H. (2010) · Molecular Immunology · doi:10.1016/j.molimm.2010.09.009 · Cited by 31 · see citing works

Interleukin-10 secretion from CD14+ peripheral blood mononuclear cells is downregulated in patients with acne vulgaris

Caillon, F., O’Connell, M., Eady, E. A., Jenkins, G. R., Cove, J. H., Layton, A., & Mountford, A. P. (2009) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2009.09420.x · Cited by 31 · see citing works

Immune evasive mechanisms contributing to persistent Leishmania donovani infection

Stäger, S., Joshi, T., & Bankoti, R. (2010) · Immunologic Research · doi:10.1007/s12026-009-8135-4 · Cited by 30 · see citing works

Interleukin-10 promoter polymorphisms associated with susceptibility to lumbar disc degeneration in a Chinese cohort

Lin, W., Lin, J., Chen, X. W., Wu, C., Zhang, L., Huang, Z. D., & Lai, J. (2011) · Genetics and Molecular Research · doi:10.4238/vol10-3gmr1283 · Cited by 29 · see citing works

Genetic variation in IL-10 influences the progression of hepatitis B infection

Rybicka, M., Woziwodzka, A., Sznarkowska, A., Romanowski, T., Stalke, P., Dręczewski, M., Verrier, E. R., Baumert, T. F., & Bielawski, K. P. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.04.079 · Cited by 28 · see citing works

Gender-specific effects of cytokine gene polymorphisms on childhood vaccine responses

Baynam, G. S., Zhang, G., Khoo, S., Sly, P. D., Holt, P. G., Goldblatt, J., & Souëf, P. N. L. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.05.011 · Cited by 28 · see citing works

Interleukin Gene Variability and Periodontal Bacteria in Patients with Generalized Aggressive Form of Periodontitis

Linhartová, P. B., Daněk, Z., Deissová, T., Hromčík, F., Lipový, B., Szaraz, D., Jánoš, J., Fassmann, A., Bártová, J., Drízhal, I., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134728 · Cited by 27 · see citing works

Cardiovascular Disease in Kidney Transplant Recipients: The Prognostic Value of Inflammatory Cytokine Genotypes

Manna, G. L., Cappuccilli, M. L., Cianciolo, G., Conte, D., Comai, G., Carretta, E., Scolari, M. P., & Stefoni, S. (2010) · Transplantation · doi:10.1097/tp.0b013e3181ce243f · Cited by 26 · see citing works

Relevance of Gamma Interferon, Tumor Necrosis Factor Alpha, and Interleukin-10 Gene Polymorphisms to Susceptibility to Mediterranean Spotted Fever

Forte, G. I., Scola, L., Misiano, G., Milano, S., Mansueto, P., Vitale, G., Bellanca, F., Sanacore, M., Vaccarino, L., Rini, G. B., et al. (2009) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00121-09 · Cited by 26 · see citing works

Interleukin‐10 promoter polymorphisms are associated with the mode and sequel of HBeAg seroconversion in patients with chronic hepatitis B virus infection

Peng, X.-M., Huang, Y. S., Ma, H. H., Gu, L., Xie, Q. F., & Gao, Z. L. (2006) · Liver International · doi:10.1111/j.1478-3231.2005.01241.x · Cited by 26 · see citing works

Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia

Dickinson, A. M., Pearce, K. F., Norden, J., O'Brien, S. G., Holler, E., Bickeböller, H., Balavarca, Y., Rocha, V., Kolb, H., Hromadníková, I., et al. (2010) · Haematologica · doi:10.3324/haematol.2009.016220 · Cited by 26 · see citing works

The interleukin-10 family cytokines gene polymorphisms in plaque psoriasis

Kingo, K. (2005) · DSpace repository (University of Tartu) · Cited by 26 · see citing works

A single nucleotide polymorphism on the IL-10 locus defines an expression polymorphism and a possible risk factor to develop RA

Lard, L. R., Schonkeren, J. J. M., Pieterman, E. J., Westendorp, R. G. J., Breedveld, F. C., & Huizinga, T. W. J. (2001) · Arthritis Research & Therapy · doi:10.1186/ar202

THU0026 A single nucleotide polymorphism on the il-10 locus defines an expression polymorphism and a possible risk factor to develop ra

Lard, L. R., Schonkeren, J. J. M., Pieterman, E. J., Westendorp, R., Breedveld, F. C., & Huizinga, T. W. J. (2001) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2001.823

Mosaics of gene variations in the Interleukin-10 gene promoter affect interleukin-10 production depending on the stimulation used

Mörmann, M., Rieth, H., Hua, T.-D., Assohou, C., Roupelieva, M., Hu, S. L., Kremsner, P. G., Luty, A. J. F., & Kube, D. (2004) · Genes and Immunity · doi:10.1038/sj.gene.6364073 · Cited by 98 · see citing works

The influence of genetic variation on innate immune activation in an environment with high infectious pressure

Boef, A. G. C., May, L., van Bodegom, D., Kuningas, M., Eriksson, U. K., & Westendorp, R. G. J. (2011) · Genes and Immunity · doi:10.1038/gene.2011.57 · Cited by 12 · see citing works

39. Heritability of interleukin-6 and its receptor in adult twins

Amaral, W. Z., & Coe, C. L. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.07.063