Differential Effects of Antidepressants on Glucocorticoid Receptors in Human Primary Blood Cells and Human Monocytic U-937 Cells

The Corticosteroid Receptor Hypothesis of Depression

Holsboer, F. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00159-7 · Cited by 2,181 · see citing works

The role of corticotropin-releasing factor in depression and anxiety disorders

Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378 · see citing works

Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment

Pariante, C. M., & Miller, A. H. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01088-x · Cited by 1,147 · see citing works

Evidence for an immune response in major depression: A review and hypothesis

Maes, M. (1995) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(94)00101-m · Cited by 1,003 · see citing works

Psychopharmacology: The Fourth Generation of Progress

Kramlinger, K. G. (1995) · Mayo Clinic Proceedings · doi:10.4065/70.10.1021-a · Cited by 779 · see citing works

Cytokine Production and Treatment Response in Major Depressive Disorder

Lanquillon, S. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00134-7 · Cited by 735 · see citing works

Steroid hormone receptors: an update

Beato, M. (2000) · Human Reproduction Update · doi:10.1093/humupd/6.3.225 · Cited by 615 · see citing works

Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression

Maes, M. H. J., Scharpé, S., Meltzer, H. Y., Bosmans, E., Suy, E., Calabrese, J. R., & Cosyns, P. R. (1993) · Psychiatry Research · doi:10.1016/0165-1781(93)90027-e · Cited by 439 · see citing works

Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system?

Barden, N., Reul, J. M., & Holsboer, F. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93942-q · Cited by 410 · see citing works

Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?

(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.8.1189 · Cited by 364 · see citing works

Negative Immunoregulatory Effects of Antidepressants Inhibition of Interferon-γ and Stimulation of Interleukin-10 Secretion

Maes, M. H. J. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00088-8 · Cited by 357 · see citing works

Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system

Reul, J. M. H. M., Stec, I. S. M., Söder, M., & Holsboer, F. (1993) · Endocrinology · doi:10.1210/endo.133.1.8391426 · Cited by 346 · see citing works

Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications.

Brady, L. S., Whitfield, H. J., Fox, R. J., Gold, P. W., & Herkenham, M. A. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115086 · Cited by 338 · see citing works

The DST as a predictor of outcome in depression: a meta-analysis

Ribeiro, S. C. M., Tandon, R., Grunhaus, L. J., & Greden, J. F. (1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.11.1618 · Cited by 329 · see citing works

Tricyclic antidepressants inhibit IL-6, IL-1β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells

Xia, Z., DePierre, J. W., & Nässberger, L. (1996) · Immunopharmacology · doi:10.1016/0162-3109(96)00111-7 · Cited by 318 · see citing works

The monocyte-T-lymphocyte hypothesis of major depression

Maes, M., Smith, R., & Simon, S. (1995) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)00066-j · Cited by 299 · see citing works

Antidepressants Increase Glucocorticoid and Mineralocorticoid Receptor mRNA Expression in Rat Hippocampus in vivo

Seckl, J. R., & Fink, G. (2008) · Neuroendocrinology · doi:10.1159/000126180 · Cited by 255 · see citing works

Prediction of Medium-Term Outcome by Cortisol Response to the Combined Dexamethasone-CRH Test in Patients With Remitted Depression

Zobel, A. W., Yassouridis, A., Frieboes, R.-M., & Holsboer, F. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.6.949 · Cited by 228 · see citing works

Corticosteroid Receptor Function Is Decreased in Depressed Patients

Modell, S., Yassouridis, A., Huber, J., & Holsboer, F. (2008) · Neuroendocrinology · doi:10.1159/000127275 · Cited by 204 · see citing works

Hypothalamic-Pituitary-Adrenocortical Axis Changes in the Rat after Long-Term Treatment with the Reversible Monoamine Oxidase-A Inhibitor Moclobemide

Reul, J. M. H. M., Labeur, M. S., Grigoriadis, D. E., Souza, E. B. D., & Holsboer, F. (2008) · Neuroendocrinology · doi:10.1159/000126788 · Cited by 174 · see citing works

Inflammatory markers in major depression and melancholia.

Rothermundt, M., Arolt, V., Peters, M., Gutbrodt, H., Fenker, J., Kersting, A., & Kirchner, H. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00157-9 · Cited by 174 · see citing works

Antidepressants enhance glucocorticoid receptor function <i>in vitro</i> by modulating the membrane steroid transporters

Pariante, C. M., Makoff, A., Lovestone, S., Feroli, S., Heyden, A., Miller, A. H., & Kerwin, R. W. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704368 · Cited by 159 · see citing works

Steroid-Independent Translocation of the Glucocorticoid Receptor by the Antidepressant Desipramine

Pariante, C. M., Pearce, B. D., Pisell, T. L., Owens, M. J., & Miller, A. H. (1997) · Molecular Pharmacology · doi:10.1124/mol.52.4.571 · Cited by 156 · see citing works

Antidepressants regulate glucocorticoid receptor messenger RNA concentrations in primary neuronal cultures

Pépin, M.-C., Beaulieu, S., & Barden, N. (1989) · Molecular Brain Research · doi:10.1016/0169-328x(89)90031-4 · Cited by 136 · see citing works

Dexamethasone for the treatment of depression: a randomized, placebo- controlled, double-blind trial

Arana, G. W., Santos, A. B., Laraia, M. T., McLeod-Bryant, S., Beale, M. D., Rames, L. J., Roberts, J. M., Dias, J. K., & Molloy, M. A. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.2.265 · Cited by 127 · see citing works

Gene regulation by steroid hormones

Beato, M., Arnemann, J., Chalepakis, G., Slater, E. P., & Willmann, T. (1987) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(87)90288-3 · Cited by 127 · see citing works

Major depressive disorder is associated with elevated monocyte counts

Seidel, A., Arolt, V., Hunstiger, M., Rink, L., Behnisch, A., & Kirchner, H. (1996) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1996.tb09849.x · Cited by 123 · see citing works

Increased glucocorticoid receptor gene promoter activity after antidepressant treatment.

Pépin, M.-C., Govindan, M. V., & Barden, N. (1992) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09226-0 · Cited by 113 · see citing works

Antidepressant drugs inhibit glucocorticoid receptor‐mediated gene transcription – a possible mechanism

Budziszewska, B., Jaworska-Feil, L., Kajta, M., & Lasoń, W. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703445 · Cited by 108 · see citing works

The Neuroendocrinology of Mood Disorders

Rubín, R. T., & Carroll, B. J. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00092-9 · Cited by 103 · see citing works

Long‐Term Treatment with Antidepressants Increases Glucocorticoid Receptor Binding and Gene Expression in Cultured Rat Hippocampal Neurones

Okugawa, Omori, Suzukawa, Fujiseki, Kinoshita, T., & Inagaki, C. (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00405.x · Cited by 92 · see citing works

Neuroendocrinology of mood disorders.

Mazza, M., Satta, M. A., Bria, P., & Mazza, S. (2004) · PubMed · Cited by 79 · see citing works

The effect of long-term treatment with antidepressant drugs on the hippocampal mineralocorticoid and glucocorticoid receptors in rats

Prezegaliński, E., & Budziszewska, B. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90297-x · Cited by 56 · see citing works

Chiral determination of mirtazapine in human blood plasma by high-performance liquid chromatography

Dodd, S., Burrows, G. D., & Norman, T. R. (2000) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/s0378-4347(00)00353-4 · Cited by 53 · see citing works

Glucocorticoid receptors in depression.

Pariante, C. M., Nemeroff, C. B., & Miller, A. H. (1995) · PubMed · Cited by 51 · see citing works

Indole-pyruvic acid, a tryptophan ketoanalogue, antagonizes the endocrine but not the behavioral effects of repeated stress in a model of depression

Biagini, G., Pich, E. M., Carani, C., Marrama, P., Gustafsson, J.-Α., Fuxé, K., & Agnati, L. F. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90121-s · Cited by 48 · see citing works

The effect of repeated combined treatment with nifedipine and antidepressant drugs or electroconvulsive shock on the hippocampal corticosteroid receptors in rats

Przegaliński, E., Budziszewska, B., Siwanowicz, J., & Jaworska, L. (1993) · Neuropharmacology · doi:10.1016/0028-3908(93)90036-3 · Cited by 39 · see citing works

The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus.

Budziszewska, B., Siwanowicz, J., & Przegaliński, E. (1995) · PubMed · Cited by 39 · see citing works

Regulation of glucocorticoidreceptor-mRNA in human blood cells by amitriptyline and dexamethasone

Vedder, H. (1999) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(99)00006-0 · Cited by 36 · see citing works

Modulation of Cellular Expression of Glucocorticoid Receptor and Glucocorticoid Response Element-DNA Binding in Rat Brain during Alcohol Drinking and Withdrawal

Roy, A., Mittal, N., Zhang, H., & Pandey, S. C. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.301.2.774 · Cited by 33 · see citing works

The Mitogen-Activated Protein Kinase Pathway Inhibits Ceramide-Induced Terminal Differentiation of a Human Monoblastic Leukemia Cell Line, U937

Ragg, S. J., Kaga, S., Berg, K. A., & Ochi, A. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.3.1390 · Cited by 29 · see citing works

Ethanol-mediated regulation of transcription factors in immunocompetent cells

Szabó, G. (2002) · Frontiers in bioscience · doi:10.2741/a742 · Cited by 17 · see citing works

Effects of Chronic Antidepressant Treatment on the Hypothalamic‐Pituitary‐Adrenal Axis of Wistar Rats

Peeters, B. W. M. M., HEIJDEN, R. V. D., GUBBELS, D. G., et al. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb39282.x · Cited by 14 · see citing works

Ethanol-mediated regulation of transcription factors in immunocompetent cells

Szabó, G. (2002) · Frontiers in bioscience · doi:10.2741/szabo · Cited by 9 · see citing works

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

Anacker, C., Zunszain, P. A., Carvalho, L. A., & Pariante, C. M. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.03.007 · Cited by 592 · see citing works

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

Anacker, C., Zunszain, P. A., Cattaneo, A., Carvalho, L. A., Garabedian, M. J., Thuret, S., Price, J., & Pariante, C. M. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.26 · Cited by 435 · see citing works

Do antidepressants regulate how cortisol affects the brain?

Pariante, C. M., Thomas, S. A., Lovestone, S., Makoff, A., & Kerwin, R. W. (2004) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2003.10.009 · Cited by 194 · see citing works

Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients

Menke, A., Arloth, J., Pütz, B., Weber, P., Klengel, T., Mehta, D., Gonik, M., Rex-Haffner, M., Rubel, J., Uhr, M., et al. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.331 · Cited by 177 · see citing works

Genetic variation in <scp>FKBP5</scp> associated with the extent of stress hormone dysregulation in major depression

Menke, A., Klengel, T., Rubel, J., Brückl, T., Pfister, H., Lucae, S., Uhr, M., Holsboer, F., & Binder, E. B. (2013) · Genes, Brain and Behavior · doi:10.1111/gbb.12026 · Cited by 151 · see citing works

Reduced Glucocorticoid Receptor α Expression in Mood Disorder Patients and First-Degree Relatives

Matsubara, T., Funato, H., Kobayashi, A., Nobumoto, M., & Watanabe, Y. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.09.026 · Cited by 94 · see citing works

Clomipramine in vitro reduces glucocorticoid receptor function in healthy subjects but not in patients with major depression

Carvalho, L. A., Juruena, M. F., Papadopoulos, A. S., Poon, L., Kerwin, R., Cleare, A. J., & Pariante, C. M. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.44 · Cited by 75 · see citing works

The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice

Yau, J. L. W., Noble, J., Thomas, S., Kerwin, R., Morgan, P. E., Lightman, S., Seckl, J. R., & Pariante, C. M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301389 · Cited by 46 · see citing works

Effects of antidepressants on mRNA levels of antioxidant enzymes in human monocytic U-937 cells

Schmidt, A. J., Heiser, P., Hemmeter, U. M., Krieg, J.-C., & Vedder, H. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.05.024 · Cited by 40 · see citing works

Central glucocorticoid receptor-mediated effects of the antidepressant, citalopram, in humans: a study using EEG and cognitive testing

Pariante, C. M., Alhaj, H. A., Arulnathan, V. E., Gallagher, P., Hanson, A., Massey, E., & McAllister-Williams, R. H. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.08.011 · Cited by 33 · see citing works

Differential effects of antidepressants on dexamethasone-induced nuclear translocation and expression of glucocorticoid receptor

Funato, H., Kobayashi, A., & Watanabe, Y. (2006) · Brain Research · doi:10.1016/j.brainres.2006.08.029 · Cited by 28 · see citing works

Mianserin versus maprotiline in patients with a depressive syndrome.

Indaco, A., Orefice, G., & Carrieri, P. B. (1984) · PubMed

Mianserin, maprotiline and the electroencephalogram.

Sedgwick, E. M., & Edwards, J. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb05873.x · Cited by 10 · see citing works

Maprotiline, nomifensine, mianserin, zimelidine: A review of antidepressant efficacy in in-patients

Montgomery, S. (1980) · Neuropharmacology · doi:10.1016/0028-3908(80)90199-9 · Cited by 33 · see citing works

A comparative study of mirtazapine and maprotiline in the treatment of treatment - resistant depression

Guo, D. (2004) · Medical Journal of Chinese People Heacth

Effects of antidepressants on alcohol-induced gastric mucosal injury in rats.

Fernández de la Gandara, F., Carnicero, J. C., & Velasco Martin, A. (1989) · PubMed · Cited by 5 · see citing works