The Selective Serotonin-2A Receptor Antagonist M100907 Reverses Behavioral Deficits in Dopamine Transporter Knockout Mice

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., & Caron, M. G. (1996) · Nature · doi:10.1038/379606a0 · Cited by 2,476

Molecular, pharmacological and functional diversity of 5-HT receptors

Hoyer, D., Hannon, J. P., & Martin, G. R. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00746-8 · Cited by 1,898

Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

BRAFF, D. L., Geyer, M. A., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100810 · Cited by 1,701

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

Geyer, M. A., Krebs-Thomson, K., Braff, D. L., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100811 · Cited by 1,484

Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input.

Hoffman, H. S., & Ison, J. R. (1980) · Psychological Review · doi:10.1037/0033-295x.87.2.175 · Cited by 780

The Role of Serotonin in Antipsychotic Drug Action

Meltzer, H. M. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00046-9 · Cited by 672

Using an Animal Model of Deficient Sensorimotor Gating to Study the Pathophysiology and New Treatments of Schizophrenia

Swerdlow, N. R., & Geyer, M. A. (1998) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033326 · Cited by 626

5-Hydroxytryptamine 2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

Jakab, R. L., & Goldman-Rakic, P. S. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.2.735 · Cited by 536

Serotonin model of schizophrenia: emerging role of glutamate mechanisms

Aghajanian, G. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00046-6 · Cited by 529

Serotonin and hallucinogens

Aghajanian, G. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00135-3 · Cited by 371

Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission

Alex, K. D., & Pehek, E. A. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.08.004 · Cited by 658

Realistic expectations of prepulse inhibition in translational models for schizophrenia research

Swerdlow, N. R., Weber, M., Qu, Y., Light, G. A., & Braff, D. L. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1072-4 · Cited by 529

Schizophrenia-Relevant Behavioral Testing in Rodent Models: A Uniquely Human Disorder?

Powell, C. M., & Miyakawa, T. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.008 · Cited by 381

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299

Animal models of attention-deficit hyperactivity disorder

Russell, V. A., Sagvolden, T., & Johansen, E. B. (2005) · Behavioral and Brain Functions · doi:10.1186/1744-9081-1-9 · Cited by 248

Prepulse inhibition and genetic mouse models of schizophrenia

Powell, S. B., Zhou, X., & Geyer, M. A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.04.021 · Cited by 218

Evidence for the Preferential Involvement of 5-HT2A Serotonin Receptors in Stress- and Drug-Induced Dopamine Release in the Rat Medial Prefrontal Cortex

Pehek, E. A., Nocjar, C., Roth, B. L., Byrd, T. A., & Mabrouk, O. S. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300819 · Cited by 212

Trace amine-associated receptor 1—Family archetype or iconoclast?

Grandy, D. K. (2007) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2007.06.007 · Cited by 198

Overview of Animal Models of Attention Deficit Hyperactivity Disorder (ADHD)

Russell, V. A. (2011) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0935s54 · Cited by 182

Exploration of 19 serotoninergic candidate genes in adults and children with attention-deficit/hyperactivity disorder identifies association for 5HT2A, DDC and MAOB

Marta Ribasés, A., Ramos‐Quiroga, J. A., Amaia Hervas, G., Bosch, R., Bielsa, A., Gastaminza, X., Artigas-Pallarés, J., Rodriguez-Ben, S., Estivill, X., Casas, M., et al. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002100 · Cited by 154

Neurobiology of animal models of attention-deficit hyperactivity disorder

Russell, V. A. (2006) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2006.12.005 · Cited by 150

Does serotonin deficit mediate susceptibility to ADHD?

Banerjee, E., & Nandagopal, K. (2015) · Neurochemistry International · doi:10.1016/j.neuint.2015.02.001 · Cited by 133

Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease

Lohr, K. M., Masoud, S. T., Salahpour, A., & Miller, G. W. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13357 · Cited by 126

A reverse-translational approach to bipolar disorder: Rodent and human studies in the Behavioral Pattern Monitor

Young, J. W., Minassian, A., Paulus, M. P., Geyer, M. A., & Perry, W. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.05.009 · Cited by 122

Genetic Mouse Models of Schizophrenia: From Hypothesis-Based To Susceptibility Gene-Based Models

Chen, J., Lipska, B. K., & Weinberger, D. R. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.024 · Cited by 108

Review of rodent models of attention deficit hyperactivity disorder

Regan, S. L., Williams, M. T., & Vorhees, C. V. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.041 · Cited by 113

Psychostimulant withdrawal as an inducing condition in animal models of depression

Barr, A. M., & Markou, A. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.012 · Cited by 112

Role of the serotonin system in ADHD: treatment implications

Oades, R. D. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.10.1357 · Cited by 95

“Selective” serotonin 5-HT2A receptor antagonists

Casey, A. B., Cui, M., Booth, R. G., & Canal, C. E. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115028 · Cited by 94

Psychostimulant-Induced Attenuation of Hyperactivity and Prepulse Inhibition Deficits inAdcyap1-Deficient Mice

Tanaka, K., Shintani, N., Hashimoto, H., Kawagishi, N., Ago, Y., Matsuda, T., Hashimoto, R., Kunugi, H., Yamamoto, A., Kawaguchi, C., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4376-05.2006 · Cited by 85

Dopamine transporter mutant animals: a translational perspective

Efimova, E. V., Gainetdinov, R. R., Budygin, E. A., & Sotnikova, T. D. (2016) · Journal of Neurogenetics · doi:10.3109/01677063.2016.1144751 · Cited by 86

Transgenic mouse models for ADHD

Leo, D., & Gainetdinov, R. R. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1639-1 · Cited by 86

Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models

Homberg, J. R., Kyzar, E. J., Nguyen, M., Norton, W., Pittman, J. T., Poudel, M. K., Gaikwad, S., Nakamura, S., Koshiba, M., Yamanouchi, H., et al. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.013 · Cited by 86

Alterations of dopamine and serotonin transmission in schizophrenia

Remington, G. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00906-0 · Cited by 83

Norepinephrine Transporter Blockade can Normalize the Prepulse Inhibition Deficits Found in Dopamine Transporter Knockout Mice

Yamashita, M., Fukushima, S., Shen, H.-W., Hall, F. S., Uhl, G. R., Numachi, Y., Kobayashi, H., & Sora, I. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301009 · Cited by 77

Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice

Meck, W. H., Cheng, R., MacDonald, C. J., Gainetdinov, R. R., Caron, M. G., & Çevik, M. Ö. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.042 · Cited by 77

Attention-deficit/hyperactive disorder updates

Kessi, M., Duan, H., Xiong, J., Chen, B., He, F., Yang, L., Ma, Y., Bamgbade, O. A., Peng, J., & Yin, F. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.925049 · Cited by 93

Dopamine transporter mutant mice in experimental neuropharmacology

Gainetdinov, R. R. (2007) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-007-0216-0 · Cited by 79

Dopamine transporter‐dependent and ‐independent actions of trace amine β‐phenylethylamine

Sotnikova, T. D., Budygin, E. A., Jones, S. R., Dykstra, L., Caron, M. G., & Gainetdinov, R. R. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02721.x · Cited by 74

The dopamine transporter role in psychiatric phenotypes

Salatino‐Oliveira, A., Rohde, L. A., & Hutz, M. H. (2017) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32578 · Cited by 73

Implications of genome wide association studies for addiction: Are our a priori assumptions all wrong?

Hall, F. S., Drgonová, J., Jain, S., & Uhl, G. R. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.07.006 · Cited by 76

Role of the serotonin 5-HT2A receptor in the hyperlocomotive and hyperthermic effects of (+)-3,4-methylenedioxymethamphetamine

Herin, D. V., Liu, S., Ullrich, T., Rice, K. C., & Cunningham, K. A. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2030-4 · Cited by 69

Cross-species assessments of motor and exploratory behavior related to bipolar disorder

Henry, B. L., Minassian, A., Young, J. W., Paulus, M. P., Geyer, M. A., & Perry, W. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.04.002 · Cited by 65

Heterozygous reeler mice exhibit alterations in sensorimotor gating but not presynaptic proteins

Barr, A. M., Fish, K. N., Markou, A., & Honer, W. G. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06233.x · Cited by 60

Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice

Powell, S. B., Young, J. W., Ong, J. C., Caron, M. G., & Geyer, M. A. (2008) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32830dc110 · Cited by 57

Nicotine Improves Cognitive Deficits of Dopamine Transporter Knockout Mice without Long-Term Tolerance

Weiss, S., Nosten‐Bertrand, M., McIntosh, J. M., Giros, B., & Martres, M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301385 · Cited by 58

Animal models of tic disorders: A translational perspective

Godar, S. C., Mosher, L. J., Giovanni, G. D., & Bortolato, M. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.09.008 · Cited by 55

Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats

Barr, A. M., Powell, S. B., Markou, A., & Geyer, M. A. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.04.004 · Cited by 49

Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer’s disease

Ceyzériat, K., Gloria, Y., Tsartsalis, S., Fossey, C., Cailly, T., Fabis, F., Millet, P., & Tournier, B. B. (2021) · Brain Communications · doi:10.1093/braincomms/fcab029 · Cited by 44

An evaluation of the serotonin system and perseverative, compulsive, stereotypical, and hyperactive behaviors in dopamine transporter (DAT) knockout mice

Fox, M. A., Panessiti, M., Hall, F. S., Uhl, G. R., & Murphy, D. L. (2013) · Psychopharmacology · doi:10.1007/s00213-013-2988-x · Cited by 49

MDMA ?ecstasy? alters hyperactive and perseverative behaviors in dopamine transporter knockout mice

Powell, S. B., Masten, V. L., Paulus, M. P., Gainetdinov, R. R., Caron, M. G., & Geyer, M. A. (2004) · Psychopharmacology · doi:10.1007/s00213-003-1765-7 · Cited by 42

Functional alterations of nicotinic neurotransmission in dopamine transporter knock-out mice

Weiss, S., Tzavara, E. T., Davis, R. J., Nomikos, G. G., McIntosh, J. M., Giros, B., & Martres, M. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.02.002 · Cited by 44

Rodent Models of ADHD

Fan, X., Bruno, K. J., & Hess, E. J. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_121 · Cited by 42

Alterations of GABAergic and dopaminergic systems in mutant mice with disruption of exons 2 and 3 of the Disc1 gene

NAKAI, T., Nagai, T., Wang, R., Yamada, S., Kuroda, K., Kaibuchi, K., & Yamada, K. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.06.009 · Cited by 41

Dissociations between interval timing and intertemporal choice following administration of fluoxetine, cocaine, or methamphetamine

Heilbronner, S. R., & Meck, W. H. (2013) · Behavioural Processes · doi:10.1016/j.beproc.2013.09.013 · Cited by 41

Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs

Sora, I., Li, B., Igari, M., Hall, F. S., & Ikeda, K. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05276.x · Cited by 38

Behavioral Animal Models of Antipsychotic Drug Actions

Peleg‐Raibstein, D., Feldon, J., & Meyer, U. (2012) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25761-2_14 · Cited by 39

Animal Models of ADHD

Bari, A., & Robbins, T. W. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_102 · Cited by 37

Activation of nucleus tractus solitarius 5‐HT2Abut not other 5‐HT2receptor subtypes inhibits the sympathetic activity in rats

Comet, M. ‐., Bernard, J., Hamon, M., Laguzzi, R. F., & Sévoz‐Couche, C. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05673.x · Cited by 34

Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered

Gaisler‐Salomon, I., Diamant, L., Rubin, C., & Weiner, I. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0960-3 · Cited by 35

Annual Research Review: Transgenic mouse models of childhood‐onset psychiatric disorders

Robertson, H. R., & Feng, G. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02380.x · Cited by 33

Cerebellar 5HT-2A receptor mediates stress-induced onset of dystonia

Kim, J. E., Chae, S., Kim, S., Jung, Y., Kang, M., Heo, W. D., & Kim, D. (2021) · Science Advances · doi:10.1126/sciadv.abb5735 · Cited by 36

Selective effects of typical antipsychotic drugs on SNAP-25 and synaptophysin in the hippocampal trisynaptic pathway

Barr, A. M., Young, C. E., Phillips, A. G., & Honer, W. G. (2005) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145705006000 · Cited by 31

Reprint of “Neurobiology of animal models of attention-deficit hyperactivity disorder”

Russell, V. A. (2007) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2006.12.020 · Cited by 29

Effects of Atomoxetine on Hyper-Locomotive Activity of the Prenatally Valproate-Exposed Rat Offspring

Choi, C. S., Hong, M., Kim, K. C., Kim, J., Yang, S. M., Seung, H., Ko, M. J., Choi, D., You, J. S., Shin, C. Y., et al. (2014) · Biomolecules & Therapeutics · doi:10.4062/biomolther.10.4062/biomolther.2014.027 · Cited by 30

From neurons to brain networks, pharmacodynamics of stimulant medication for ADHD

Parlatini, V., Bellato, A., Murphy, D., & Cortese, S. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105841 · Cited by 26

Dopamine Transporter Deficient Rodents: Perspectives and Limitations for Neuroscience

Savchenko, A. A., Targa, G., Fesenko, Z. S., Leo, D., Gainetdinov, R. R., & Sukhanov, I. (2023) · Biomolecules · doi:10.3390/biom13050806 · Cited by 31

The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice

Barr, A. M., Fish, K. N., & Markou, A. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.11.011 · Cited by 26

Strengths and limitations of genetic models of ADHD

Gainetdinov, R. R. (2010) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-010-0021-3 · Cited by 24

Research Domain Criteria versus DSM V: How does this debate affect attempts to model corticostriatal dysfunction in animals?

Young, J. W., Winstanley, C. A., Brady, A. M., & Hall, F. S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.029 · Cited by 28

Using affect‐modulated startle to study phenotypes of pediatric bipolar disorder

Rich, B. A., Bhangoo, R. K., Vinton, D. T., Berghorst, L. H., Dickstein, D. P., Grillon, C., Davidson, R. J., & Leibenluft, E. (2005) · Bipolar Disorders · doi:10.1111/j.1399-5618.2005.00265.x · Cited by 24

A translational research approach to poor treatment response in patients with schizophrenia: clozapine–antipsychotic polypharmacy

Honer, W. G., Procyshyn, R. M., Chen, E. Y. H., MacEwan, G. W., & Barr, A. M. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0954 · Cited by 23

Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT2A Receptor by In Silico Methods

Lin, F., Li, F., Wang, C., Wang, J., Yang, Y., Yang, L., & Li, Y. (2017) · Molecules · doi:10.3390/molecules22071064 · Cited by 23

The α2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats

Semenova, S., & Markou, A. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.05.003 · Cited by 22

The mGluR2/3 Agonist LY379268 Blocks the Effects of GLT-1 Upregulation on Prepulse Inhibition of the Startle Reflex in Adult Rats

Bellesi, M., & Conti, F. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.225 · Cited by 22

GBR 12909 administration as an animal model of bipolar mania: time course of behavioral, brain oxidative alterations and effect of mood stabilizing drugs

Queiroz, A. I. G., de Araújo, M. M., Araújo, T. D. S., de Souza, G. C., Cavalcante, L. M., Machado, M. D. J. S., de Lucena, D. F., Quevedo, J., & Macêdo, D. S. (2015) · Metabolic Brain Disease · doi:10.1007/s11011-015-9697-6 · Cited by 22

If waking and dreaming consciousness became de-differentiated, would schizophrenia result?

Llewellyn, S. (2011) · Consciousness and Cognition · doi:10.1016/j.concog.2011.03.022 · Cited by 21

Altered performance of reelin-receptor ApoER2 deficient mice on spatial tasks using the Barnes maze.

Barr, A. M., MacLaurin, S. A., Semenova, S., Fish, K. N., & Markou, A. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.5.1101 · Cited by 18

The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila

Karam, C. S., Williams, B. L., Jones, S. K., & Javitch, J. A. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03275-4 · Cited by 17

Effects of Atomoxetine on Motor and Cognitive Behaviors and Brain Electrophysiological Activity of Dopamine Transporter Knockout Rats

Ptukha, M. A., Fesenko, Z. S., Belskaya, A. D., Gromova, A. A., Pelevin, A., Kurzina, N. P., Gainetdinov, R. R., & Volnova, A. B. (2022) · Biomolecules · doi:10.3390/biom12101484 · Cited by 15

Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation

Santini, M. A., Klein, A. B., El-Sayed, M., Ratner, C., Knudsen, G. M., Mikkelsen, J. D., & Aznar, S. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.05.048 · Cited by 15

Antimanic activity of minocycline in a GBR12909-induced model of mania in mice: Possible role of antioxidant and neurotrophic mechanisms

Queiroz, A. I. G., Filho, A. J. M. C., Araújo, T. D. S., Lima, C. N. D. C., Machado, M. D. J. S., Carvalho, A. F., Vasconcelos, S. M. M., de Lucena, D. F., Quevedo, J., & Macêdo, D. S. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.07.053 · Cited by 16

New therapeutic potential for psychoactive natural products

Prevatt‐Smith, K. M., & Prisinzano, T. E. (2009) · Natural Product Reports · doi:10.1039/b912196j · Cited by 14

Hyperactive behavioral phenotypes and an altered brain monoaminergic state in male offspring mice with perinatal hypothyroidism

Umezu, T., Kita, T., & Morita, M. (2019) · Toxicology Reports · doi:10.1016/j.toxrep.2019.10.005 · Cited by 13

Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: A possible role of hyperforin

Tadros, M. G., Mohamed, M. R., Youssef, A. M., Sabry, G. M., Sabry, N. A., & Khalifa, A. E. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.12.015 · Cited by 13

Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in Fez1-Deficient Mice

Sumitomo, A., Saka, A., Ueta, K., Horike, K., Hirai, K., Gamo, N. J., Hikida, T., Nakayama, K. I., Sawa, A., Sakurai, T., et al. (2017) · Complex Psychiatry · doi:10.1159/000488081 · Cited by 12

Prepulse inhibition is different in two inbred mouse strains (CPB-K and BALB/cJ) with different hippocampal NMDA receptor densities

Wolf, R. J., Dobrowolny, H., Matzke, K., Paelchen, K., Bogerts, B., & Schwegler, H. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.07.027 · Cited by 12

Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice

Marques, A. M., Macena, M. V., Cardoso, A. R., Hammes, C. S. O., Pinheiro, F. M. L., Castro, N. G., & Neves, G. A. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05485-0 · Cited by 11

p-Hydroxyamphetamine causes prepulse inhibition disruption in mice: Contribution of serotonin neurotransmission

Onogi, H., Nakagawasai, O., Sato, A., Mitazaki, S., Nakaya, K., Watanabe, K., Yaoita, F., Tan–No, K., Arai, Y., Kikuchi, T., et al. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.06.002 · Cited by 9

Mutant Mouse Models in Evaluating Novel Approaches to Antipsychotic Treatment

O’Tuathaigh, C. M. P., Desbonnet, L., & Waddington, J. L. (2012) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25758-2_5 · Cited by 8

Revisiting the Role of Serotonin in Attention-Deficit Hyperactivity Disorder: New Insights from Preclinical and Clinical Studies

Solomon, M. B., Yegla, B., Newcorn, J. H., Maletic, V., Rubin, J. S., & Robbins, T. W. (2025) · Clinical Drug Investigation · doi:10.1007/s40261-025-01473-4 · Cited by 9

Role of serotonin in the neurobiology of attention-deficit/hyperactivity disorder: a systematic literature review

Faraone, S. V., Ward, C. L., Boucher, M., Elbekai, R. H., & Brunner, E. (2025) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2025.2552324 · Cited by 9

Knocking Out the Dopamine Reuptake Transporter (DAT) Does not Change the Baseline Brain Arachidonic Acid Signal in the Mouse

Ramadan, E., Chang, L., Chen, M., Ma, K., Hall, F. S., Uhl, G. R., Rapoport, S. I., & Basselin, M. (2012) · International Journal of Neuroscience · doi:10.3109/00207454.2012.665972 · Cited by 5

Attention-deficit hyperactivity disorder

Sotnikova, T. D., & Gainetdinov, R. R. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.015 · Cited by 8

The Ins and Outs of Dopamine Transporter Gene Manipulation: In Vivo Models of DAT Dysfunction

Stewart, A., & Blakely, R. (2025) · Advances in neurobiology · doi:10.1007/978-3-031-96364-3_10 · Cited by 3

Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits

Larrauri, J. A., & Levin, E. D. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.03.010 · Cited by 3

THEORETICAL AND INSILCO PHARMACOKINETIC INVESTIGATIONS ON SOME PHENYL PIPERIDINE DERIVATIVES AS NOVEL ANTIDEPRESSANT AGENTS

Olasupo, S. B., Uzairu, A., Shallangwa, G. A., & Uba, S. (2020) · The Journal of Engineering and Exact Sciences · doi:10.18540/jcecvl6iss2pp0107-0128 · Cited by 2

The metabolism of indoleamines

Tricklebank, M. D., & Martins, D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813323-1.00001-3 · Cited by 1

[Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities].

Sirotin, B. Z., & Жмеренецкий, К. В. (2003) · PubMed · Cited by 1

The role of dopamine D2 and neuregulin-1 receptors in schizophrenia relevant phenotypes of cognition, attention and memory

Mathur, N. (2012) · Nottingham ePrints (University of Nottingham) · Cited by 1

Psychopathology of psychosis: Towards integration from an idealist perspective

Behrendt, R., & Young, C. C. (2004) · Behavioral and Brain Sciences · doi:10.1017/s0140525x04440187

Étude du rôle de la dopamine et de la sérotonine dans l’effet atténuateur des antipsychotiques et de l’OSU-6162 sur la récompense induite par la stimulation du faisceau médian prosencéphalique chez le rongeur

Benaliouad, F. (2009) · doi:10.71781/30069

Social dysfunction and mental retardation

Pietropaolo, S., Sluyter, F., & Crusio, W. E. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.010

Monoaminergic Approaches for Treatment of Schizophrenia

Rotella, D. P. (2012) · Royal Society of Chemistry eBooks · doi:10.1039/9781849734943-00035

Cocaine-related disorders

Hall, F. S., & Sora, I. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.028 · Cited by 1

Papel de receptores monoaminérgicos, colinérgicos e glutamatérgicos no efeito pro-mnéstico de Ptychopetalum olacoides Bentham (Olacaceae).

Saúde, B. D. (2006)

Substance dependence and abuse

Pietropaolo, S., Sluyter, F., & Crusio, W. E. (2014) · Cambridge University Press eBooks · doi:10.1017/cbo9781107360556.024

MDL100907

DuPre, A. (2007) · xPharm: The Comprehensive Pharmacology Reference · doi:10.1016/b978-008055232-3.62107-5

References

Crawley, J. N. (2006) · Wiley eBooks · doi:10.1002/9780470119051.refs

Animal models of attention-deficit/hyperactivity disorder: Diversity and validity

Nehme, S. B. S., Sánchez‐Sarasúa, S., Medrano, M., Bouchatta, O., Bitar, T., Alameddine, A., Galineau, L., Brunault, P., Kerekes, N., Sánchez‐Pérez, A. M., et al. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100108

Serotonin 2A receptor antagonist treatment reduces dopamine D1 receptor-mediated rotational behavior but not l-DOPA-induced abnormal involuntary movements in the unilateral dopamine-depleted rat

Taylor, J. L., Bishop, C., Ullrich, T., Rice, K. C., & Walker, P. D. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.12.004 · Cited by 43

The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice

Carlsson, M. L., Martin, P., Nilsson, M., Sorensen, S. M., Carlsson, A., Waters, N., & Waters, N. (1999) · Journal of Neural Transmission · doi:10.1007/s007020050144 · Cited by 78

Acute and repeated administration of the selective 5‐HT2A receptor antagonist M100907 significantly alters the activity of midbrain dopamine neurons: An in vivo electrophysiological study

Minabe, Y., Hashimoto, K., Watanabe, K., & Ashby, C. R. (2001) · Synapse · doi:10.1002/syn.1031 · Cited by 27

The Selective 5-HT2A Receptor Antagonist M100907 Enhances Antidepressant-Like Behavioral Effects of the SSRI Fluoxetine

Marek, G. J., Martín‐Ruiz, R., Abo, A., & Artigas, F. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300762 · Cited by 123

The Effects of M100907 in Pharmacological and Developmental Animal Models of Prepulse Inhibition Deficits in Schizophrenia

Geyer, M. A. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00123-2 · Cited by 28