The ‘definitive’ (and ‘primitive’) guide to zebrafish hematopoiesis

Stages of embryonic development of the zebrafish

Kimmel, C. B., Ballard, W. W., Kimmel, S. R., Ullmann, B., & Schilling, T. F. (1995) · Developmental Dynamics · doi:10.1002/aja.1002030302 · Cited by 12,037

Hox genes in vertebrate development

Krumlauf, R. K. (1994) · Cell · doi:10.1016/0092-8674(94)90290-9 · Cited by 2,079

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80986-1 · Cited by 1,856

The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio

Haffter, P., Granato, M., Brand, M., Mullins, M. C., Hammerschmidt, M., Kane, D. A., Odenthal, J., van Eeden, F. J. M., Jiang, Y., Heisenberg, C., et al. (1996) · Development · doi:10.1242/dev.123.1.1 · Cited by 1,691

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., et al. (2000) · Nature · doi:10.1038/35001596 · Cited by 1,667

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Wang, Q., Stacy, T., Binder, M., Marin-Padilla, M., Sharpe, A. H., & Speck, N. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.8.3444 · Cited by 1,178

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Shivdasani, R. A., Mayer, E. L., & Orkin, S. H. (1995) · Nature · doi:10.1038/373432a0 · Cited by 938

Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants

Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., & Zon, L. I. (2003) · Nature Immunology · doi:10.1038/ni1007 · Cited by 800

Ontogeny and behaviour of early macrophages in the zebrafish embryo

Herbomel, P., Thisse, B., & Thisse, C. (1999) · Development · doi:10.1242/dev.126.17.3735 · Cited by 799

Origin and organization of the zebrafish fate map

Kimmel, C. B., Warga, R. M., & Schilling, T. F. (1990) · Development · doi:10.1242/dev.108.4.581 · Cited by 698

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm

Wang, H., Holland, P. W. H., & Takahashi, T. (2019) · EvoDevo · doi:10.1186/s13227-019-0128-3 · Cited by 24

Recent findings on vertebrate developmental immunity using the zebrafish model

Galindo‐Villegas, J. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.10.011 · Cited by 24

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

Dhami, S. P. S., Kappala, S. S., Thompson, A., & Szegezdi, É. (2016) · Drug Discovery Today · doi:10.1016/j.drudis.2016.04.019 · Cited by 24

The pore-forming protein Aep1 is an innate immune molecule that prevents zebrafish from bacterial infection

Chen, L., Xie, J. Z., Cao, D., Jia, N., Li, Y., Sun, H., Li, W., Hu, B., Chen, Y., & Zhou, C. (2018) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2018.01.003 · Cited by 23

Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis

Zhang, J., & Hamza, I. (2018) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2018.12.007 · Cited by 25

Distribution of the professional phagocytic granulocytes of the bony fish gilthead seabream (Sparus aurata L.) during the ontogeny of lymphomyeloid organs and pathogen entry sites

Mulero, I., Chaves-Pozo, E., García-Alcázar, A., Meseguer, J., Mulero, V., & Ayala, A. G. (2006) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2006.11.011 · Cited by 24

Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish

Sertori, R., Liongue, C., Basheer, F., Lewis, K. L. T., Rasighaemi, P., de Coninck, D., Traver, D. J., & Ward, A. C. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1403060 · Cited by 24

Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic Insights

Harrison, N. R., Laroche, F., Gutiérrez, A., & Feng, H. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-30654-4_15 · Cited by 24

A model of glucose-6-phosphate dehydrogenase deficiency in the zebrafish

Patrinostro, X., Carter, M. L., Kramer, A. C., & Lund, T. C. (2013) · Experimental Hematology · doi:10.1016/j.exphem.2013.04.002 · Cited by 23

Peering through zebrafish to understand inherited bone marrow failure syndromes

Oyarbide, U., Topczewski, J., & Corey, S. J. (2018) · Haematologica · doi:10.3324/haematol.2018.196105 · Cited by 23

Patterning definitive hematopoietic stem cells from embryonic stem cells

Lengerke, C., & Daley, G. Q. (2005) · Experimental Hematology · doi:10.1016/j.exphem.2005.06.004 · Cited by 23

Inflammation in Development and Aging: Insights from the Zebrafish Model

Mastrogiovanni, M., Martínez-Navarro, F. J., Bowman, T. V., & Cayuela, M. L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042145 · Cited by 27

Methionine aminopeptidase 2 is required for HSC initiation and proliferation

Ma, A. C. H., Fung, T. K., Lin, R. H. C., Chung, M., Yang, D., Ekker, S. C., & Leung, A. Y. H. (2011) · Blood · doi:10.1182/blood-2011-04-350173 · Cited by 22

Bef medaka mutant reveals the essential role of c-myb in both primitive and definitive hematopoiesis

Moriyama, A., Inohaya, K., Maruyama, K., & Kudō, A. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.06.031 · Cited by 22

Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish

Dong, Z., Ren, C., Xia, Y. Q., Su, D., Du, T., Fan, H.-B., Yuan, H., Wang, L., Dong, M., Li, W., et al. (2014) · Journal of Hematology & Oncology · doi:10.1186/1756-8722-7-17 · Cited by 22

Overexpression of FLT3-ITD driven by spi-1 results in expanded myelopoiesis with leukemic phenotype in zebrafish

Lu, J., Hou, H.-A., Hsieh, M.-S., Tien, H., & Lin, L. (2016) · Leukemia · doi:10.1038/leu.2016.132 · Cited by 22

Antigen Uptake during Different Life Stages of Zebrafish (Danio rerio) Using a GFP-Tagged Yersinia ruckeri

Korbut, R., Mehrdana, F., Kania, P. W., Larsen, M., Frees, D., Dalsgaard, I., & Jørgensen, L. V. G. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158968 · Cited by 22

Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio)

Harjula, S.-K. E., Saralahti, A. K., Ojanen, M. J. T., Rantapero, T., Uusi-Mäkelä, M. I. E., Nykter, M., Lohi, O., Parikka, M., & Rämet, M. (2019) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2019.103523 · Cited by 22

Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway

Antunes, A. T., Goos, Y. J., Pereboom, T. C., Hermkens, D. M. A., Włodarski, M. W., Costa, L. M. D., & MacInnes, A. W. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005326 · Cited by 27

Antisense Targeting of CXXC Finger Protein 1 Inhibits Genomic Cytosine Methylation and Primitive Hematopoiesis in Zebrafish

Young, S. R. L., Mumaw, C. L., Marrs, J. A., & Skalnik, D. G. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m604546200 · Cited by 22

Steering pluripotency and differentiation with N6-methyladenosine RNA modification

Malla, S., Melguizo‐Sanchis, D., & Aguiló, F. (2018) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2018.10.013 · Cited by 21

Retinoic Acid Signaling Plays a Restrictive Role in Zebrafish Primitive Myelopoiesis

Liang, D., Jia, W., Li, J., Li, K., & Zhao, Q. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030865 · Cited by 21

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

Rasighaemi, P., Onnebo, S. M. N., Liongue, C., & Ward, A. C. (2014) · Haematologica · doi:10.3324/haematol.2014.104091 · Cited by 21

Endothelium is required for the promotion of interrenal morphogenetic movement during early zebrafish development

Liu, Y., & Guo, L. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.04.464 · Cited by 21

Molecular characterization of the murine homologue of the DC-derived protein DC-SCRIPT

Triantis, V., Moulin, V., Looman, M. W. G., Hartgers, F. C., Janssen, R. A. J., & Adema, G. J. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.1005588 · Cited by 21

Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties

Tsinkalovsky, O., Vik‐Mo, A. O., Ferreira, S., Lærum, O. D., & Fjose, A. (2006) · Differentiation · doi:10.1111/j.1432-0436.2006.00130.x · Cited by 20

Evidence for the conservation of miR-223 in zebrafish (Danio rerio): Implications for function

Roberto, V. P., Tiago, D. M., Gautvik, K. M., & Cancela, M. L. (2015) · Gene · doi:10.1016/j.gene.2015.04.022 · Cited by 20

Visualizing and quantifying Pseudomonas aeruginosa infection in the hindbrain ventricle of zebrafish using confocal laser scanning microscopy

Rocker, A. J., Weiss, A. R. E., Lam, J. S., Raay, T. J. V., & Khursigara, C. M. (2015) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2015.07.013 · Cited by 19

Large-Scale Forward Genetic Screening Analysis of Development of Hematopoiesis in Zebrafish

Wang, K., Huang, Z., Zhao, L., Liu, W., Chen, X., Meng, P., Lin, Q., Chi, Y., Xu, M., Ma, N., et al. (2012) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2012.07.008 · Cited by 20

Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene

Kwan, T. T. F., Liang, R. H. S., Verfaillie, C. M., Ekker, S. C., Chan, L. C., Lin, S., & Leung, A. Y. H. (2006) · Experimental Hematology · doi:10.1016/j.exphem.2005.09.017 · Cited by 20

Regulation of Stem Cells in the Zebra Fish Hematopoietic SystemPreprint

Huang, H.-T., & Zon, L. I. (2008) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2008.73.029 · Cited by 20

Novel Zebrafish Patient-Derived Tumor Xenograft Methodology for Evaluating Efficacy of Immune-Stimulating BCG Therapy in Urinary Bladder Cancer

Kowald, S., Huge, Y., Tandiono, D., Ali, Z., Rodriguez, G. V., Erkstam, A., Fahlgren, A., Sherif, A. M., Cao, Y., & Jensen, L. D. (2023) · Cells · doi:10.3390/cells12030508 · Cited by 19

Small Molecule Screen in Zebrafish and HSC Expansion

Trompouki, E., & Zon, L. I. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-691-7_19 · Cited by 19

Molecular and functional characterization of the voltage‐gated proton channel in zebrafish neutrophils

Ratanayotha, A., Kawai, T., Higashijima, S., & Okamura, Y. (2017) · Physiological Reports · doi:10.14814/phy2.13345 · Cited by 19

Histology of major organ systems of Nothobranchius fishes: short-lived model species

Dyková, I., Žák, J., Blažek, R., Reichard, M., Součková, K., & Slabý, O. (2022) · Folia Zoologica · doi:10.25225/jvb.21074 · Cited by 25

Homing Sweet Homing: Odyssey of Hematopoietic Stem Cells

Burns, C. E., & Zon, L. I. (2006) · Immunity · doi:10.1016/j.immuni.2006.11.006 · Cited by 19

Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor

Piechowski, J. M., & Bagatto, B. P. (2021) · Birth Defects Research · doi:10.1002/bdr2.1951 · Cited by 18

Haematopoiesis in Zebrafish (Danio Rerio)

Stosik, M. P., Tokarz–Deptuła, B., & Deptuła, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.902941 · Cited by 18

Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2

Mattonet, K., Riemslagh, F. W., Günther, S., Prummel, K. D., Kesavan, G., Hans, S., Ebersberger, I., Brand, M., Burger, A., Reischauer, S., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn2082 · Cited by 18

Zebrafish as a Model for the Study of Human Myeloid Malignancies

Lu, J., Hsieh, M., Liao, H.-A., Yang, Y., Ho, Y., & Lin, L. (2015) · BioMed Research International · doi:10.1155/2015/641475 · Cited by 18

Chromatin programming by developmentally regulated transcription factors: lessons from the study of haematopoietic stem cell specification and differentiation

Obier, N., & Bonifer, C. (2016) · FEBS Letters · doi:10.1002/1873-3468.12343 · Cited by 18

Psychoneuroimmunology and immunopsychiatry of zebrafish

de Abreu, M. S., Giacomini, A. C. V. V., Zanandrea, R., dos Santos, B. E., Genário, R., de Oliveira, G. G., Friend, A. J., Amstislavskaya, T. G., & Kalueff, A. V. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.03.014 · Cited by 19

Isolation, identification and pathogenicity study of emerging multi-drug resistant fish pathogen Acinetobacter pittii from diseased rohu (Labeo rohita) in India

Laltlanmawia, C., Ghosh, L., Saha, R. K., Parhi, J., Pal, P., Dhar, B., & Saha, H. (2023) · Aquaculture Reports · doi:10.1016/j.aqrep.2023.101629 · Cited by 17

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish

Goody, M. F., Peterman, E., Sullivan, C., & Kim, C. H. (2013) · Journal of Visualized Experiments · doi:10.3791/50667 · Cited by 17

Developmental HSC Microenvironments: Lessons from Zebrafish

Nik, S., Weinreb, J. T., & Bowman, T. V. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-69194-7_4 · Cited by 17

Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish

Seiler, C., Gebhart, N., Zhang, Y., Shinton, S. A., Li, Y., Ross, N. L., Liu, X., Li, Q., Bilbee, A. N., Varshney, G. K., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131908 · Cited by 17

Regulation of Teleost Macrophage and Neutrophil Cell Development by Growth Factors and Transcription Factors

Barbara, A., Katakura, F., & Belosevic, M. (2012) · InTech eBooks · doi:10.5772/53589 · Cited by 16

Functional C1q is present in the skin mucus of Siberian sturgeon ( Acipenser baerii )

Fan, C., Jian, W. A. N. G., Zhang, X., & Song, J. (2014) · Integrative Zoology · doi:10.1111/1749-4877.12100 · Cited by 16

Regulation of Embryonic Hematopoiesis by a Cytokine-Inducible SH2 Domain Homolog in Zebrafish

Lewis, R. S., Noor, S. M., Fraser, F. W., Sertori, R., Liongue, C., & Ward, A. C. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1301376 · Cited by 16

Endocardium gives rise to blood cells in zebrafish embryos

Gurung, S., Restrepo, N. K., & Sumanas, S. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113736 · Cited by 15

Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG therapy

Martínez-López, M. F., de Almeida, C. R., Fontes, M., Mendes, R. V., Kaufmann, S. H. E., & Fior, R. (2024) · Disease Models & Mechanisms · doi:10.1242/dmm.050693 · Cited by 15

p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulation

Campbell, C. A., Calderon, R., Pavani, G., Cheng, X., Barakat, R., Snella, E. M., Liu, F., Peng, X., Essner, J. J., Dorman, K. S., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51922-5 · Cited by 16

Functional Analysis of Two Novel Streptococcus iniae Virulence Factors Using a Zebrafish Infection Model

Soh, K. Y., Loh, J. M. S., Hall, C. J., & Proft, T. (2020) · Microorganisms · doi:10.3390/microorganisms8091361 · Cited by 15

Zebrafish models of acute leukemias: Current models and future directions

Molina, B., Chavez, J., & Grainger, S. J. (2020) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.400 · Cited by 16

Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish

Jing, C., Chen, Y., Dong, M., Peng, X.-L., Jia, X., Gao, L., Ma, K., Deng, M., Liu, T.-X., Zon, L. I., et al. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.11.032 · Cited by 15

Tumor necrosis factor–related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus

Tamura, K., Mawaribuchi, S., Yoshimoto, S., Shiba, T., Takamatsu, N., & Ito, M. (2009) · Blood · doi:10.1182/blood-2009-04-218966 · Cited by 15

Let's get small (and smaller): Combining zebrafish and nanomedicine to advance neuroregenerative therapeutics

White, D. T., Saxena, M. T., & Mumm, J. S. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.011 · Cited by 15

Dissection of the Adult Zebrafish Kidney

Gerlach, G. F., Schrader, L. N., & Wingert, R. A. (2011) · Journal of Visualized Experiments · doi:10.3791/2839-v · Cited by 16

The C-MYB story—is it definitive?

Lipsick, J. S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012402107 · Cited by 15

Using zebrafish to model erythroid lineage toxicity and regeneration

Lenard, A., Alghisi, E., Daff, H., Donzelli, M., McGinnis, C., & Lengerke, C. (2016) · Haematologica · doi:10.3324/haematol.2016.142562 · Cited by 14

Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation

Pillay, L. M., Mackowetzky, K. J., Widen, S. A., & Waskiewicz, A. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166040 · Cited by 14

Thymus development in the zebrafish (Danio rerio) from an ecoimmunology perspective

Kernen, L., Rieder, J., Duus, A., Holbech, H., Segner, H. E., & Bailey, C. (2020) · Journal of Experimental Zoology Part A Ecological and Integrative Physiology · doi:10.1002/jez.2435 · Cited by 14

Characterization of kidney marrow in zebrafish (Danio rerio) by using a new surgical technique.

Ivanovski, O., Kulkeaw, K., Nakagawa, M., Sasaki, T., Mizuochi, C., Horio, Y., Ishitani, T., & Sugiyama, D. (2009) · PubMed · Cited by 14

Cell composition of the head kidney of European chub (Squalius cephalus L. )

Kondera, E. (2014) · Fisheries & Aquatic Life · doi:10.2478/aopf-2014-0029 · Cited by 14

Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish EmbryogenesisPreprint

Kim, Y. J., VijayKumar, S., Iovino, B. G., Granados, A. A., Ancheta, S., Frank, M., Zhao, X., Awayan, K., Seng, A., Borja, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.18.618987 · Cited by 16

Zebrafish for thrombocytopoiesis- and hemostasis-related researches and disorders

Meng, P., Wu, L., Lin, Q., & Zhang, Y. (2020) · Blood Science · doi:10.1097/bs9.0000000000000043 · Cited by 13

Caudal dorsal artery generates hematopoietic stem and progenitor cells via the endothelial-to-hematopoietic transition in zebrafish

Zhan, Y., Huang, Y., Chen, J., Cao, Z., He, J., Zhang, J., Huang, H., Ruan, H., Luo, L., & Li, L. (2018) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2018.02.010 · Cited by 13

Pro-oxidant and antioxidant responses in the liver and kidney of wild Goodea gracilis and their relation with halomethanes bioactivation

Olivares‐Rubio, H. F., Martínez-Torres, M. L., Domínguez‐López, M. L., Garcı́a-Latorre, E., & López, A. V. (2013) · Fish Physiology and Biochemistry · doi:10.1007/s10695-013-9812-8 · Cited by 13

Demonstration of T cell and macrophage progenitors in carp (Cyprinus carpio) kidney hematopoietic tissues. Development of clonal assay system for carp hematopoietic cells

Katakura, F., Yamaguchi, T., Yoshida, M., Moritomo, T., & Nakanishi, T. (2010) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2010.01.015 · Cited by 13

In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay

Arulmozhivarman, G., Stöter, M., Bickle, M., Kräter, M., Wobus, M., Ehninger, G., Stölzel, F., Brand, M., Bornhäuser, M., & Shayegi, N. (2016) · SLAS DISCOVERY · doi:10.1177/1087057116644163 · Cited by 13

Monocyte/Macrophage: NK Cell Cooperation—Old Tools for New Functions

Wałajtys-Rode, E., & Dzik, J. M. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-54090-0_5 · Cited by 13

Ncor1 and Ncor2 play essential but distinct roles in zebrafish primitive myelopoiesis

Li, J., Li, K., Dong, X., Liang, D., & Zhao, Q. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24181 · Cited by 13

SAP30L (Sin3A‐associated protein 30‐like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos

Teittinen, K. J., Grönroos, T., Parikka, M., Junttila, S., Uusimäki, A., Laiho, A., Korkeamäki, H., Kurppa, K., Turpeinen, H., Pesu, M., et al. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24298 · Cited by 13

Extra-embryonic mesoderm during development and in in vitro models

Nehme, E., Panda, A., Migeotte, I., & Pasque, V. (2025) · Development · doi:10.1242/dev.204624 · Cited by 12

Meis1, Hi1α, and GATA1 are integrated into a hierarchical regulatory network to mediate primitive erythropoiesis

Chung, H., Lin, B., Lin, Y., Chang, C., Tzou, W., Pei, T., & Hu, C. (2021) · The FASEB Journal · doi:10.1096/fj.202001044rrr · Cited by 13

Maternal pak4 expression is required for primitive myelopoiesis in zebrafish

Law, S. H. W., & Sargent, T. D. (2012) · Mechanisms of Development · doi:10.1016/j.mod.2012.09.005 · Cited by 11

Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish

Glenn, N. O., Schumacher, J. A., Kim, H. J., Zhao, E. J., Skerniškytė, J., & Sumanas, S. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.06.011 · Cited by 12

TP53 Modulates Oxidative Stress in Gata1 + Erythroid Cells

Kramer, A. C., Weber, J. M., Zhang, Y., Tolar, J., Gibbens, Y., Shevik, M. E., & Lund, T. C. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2016.12.025 · Cited by 14

Elevated phagocytic capacity directs innate spinal cord repair

Shaw, D. K., Saraswathy, V. M., McAdow, A. R., Zhou, L., Park, D., Mote, R. D., Saini, A., Douthitt, A. J., Stepankova, K., Unverzagt, B., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117482 · Cited by 12

Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish

Huang, M., Ahmed, A., Wang, W., Wang, X., Ma, C., Jiang, H., Li, W., & Jing, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073833 · Cited by 11

Csf1rb regulates definitive hematopoiesis in zebrafish

Dai, Y., Wu, S., Cao, C., Xue, R., Luo, X., Wen, Z., & Xu, J. (2022) · Development · doi:10.1242/dev.200534 · Cited by 11

Wnt8a expands the pool of embryonic kidney progenitors in zebrafish

Naylor, R. W., Han, H. I., Hukriede, N. A., & Davidson, A. J. (2017) · Developmental Biology · doi:10.1016/j.ydbio.2017.03.027 · Cited by 11

Deciphering the toxic effects of polystyrene nanoparticles on erythropoiesis at single-cell resolution

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