Differential regulation and properties of MAPKs

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

Johnson, G. L., & Lapadat, R. (2002) · Science · doi:10.1126/science.1072682 · Cited by 4,295

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

Kyriakis, J. M., & Avruch, J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.807 · Cited by 3,400

A central role for JNK in obesity and insulin resistance

Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature · doi:10.1038/nature01137 · Cited by 3,359

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Lee, J. C., Laydon, J. T., McDonnell, P., Gallagher, T. F., Kumar, S., Green, D., McNulty, D. E., Blumenthal, M. J., Keys, J., vatter, S. W. L., et al. (1994) · Nature · doi:10.1038/372739a0 · Cited by 3,266

Protein Tyrosine Phosphatases in the Human Genome

Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J., & Mustelin, T. (2004) · Cell · doi:10.1016/j.cell.2004.05.018 · Cited by 1,886

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Hibi, M., Lin, A., Smeal, T., Minden, A., & Karin, M. (1993) · Genes & Development · doi:10.1101/gad.7.11.2135 · Cited by 1,886

Signal Transduction through MAP Kinase Cascades

Lewis, T. S., Shapiro, P. S., & Ahn, N. G. (1998) · Advances in cancer research · doi:10.1016/s0065-230x(08)60765-4 · Cited by 1,759

Functional divergence caused by mutations in an energetic hotspot in ERK2

Taylor, C. A., Cormier, K. W., Keenan, S. E., Earnest, S. A., Stippec, S., Wichaidit, C., Juang, Y.-C. A., Wang, J., Shvartsman, S. Y., Goldsmith, E. J., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1905015116 · Cited by 23

ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis

Zheng, J., Shi, Z., Yang, P., Zhao, Y., Tang, W., Ye, S., Xuan, Z., Chen, C., Shao, C., Wu, Q., et al. (2022) · Life Science Alliance · doi:10.26508/lsa.202101330 · Cited by 24

The immuneoreaction and antioxidant status of Chinese mitten crab (Eriocheir sinensis) involve protein metabolism and the response of mTOR signaling pathway to dietary methionine levels

Wang, X., Lei, X., Guo, Z., Wang, S., Wan, J.-W., Liu, H., Chen, Y., Wang, G., Wang, Q., & Zhang, D. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.07.012 · Cited by 23

Modulation of protein kinase signaling cascades by palytoxin

Wattenberg, E. V. (2010) · Toxicon · doi:10.1016/j.toxicon.2010.11.003 · Cited by 23

MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide

Hsu, Y.-F., Sheu, J., Lin, C., Chen, W.-C., Hsiao, G., Ou, G., Chiu, P.-T., & Hsu, M. (2011) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.08.015 · Cited by 22

Endothelin‐1 Stimulates Proinflammatory Cytokine Expression in Human Periodontal Ligament Cells via Mitogen‐Activated Protein Kinase Pathway

Liang, L., Yu, J., Zhou, W. P., Liu, N., En, L., Wang, D. S., & Liu, H. (2013) · Journal of Periodontology · doi:10.1902/jop.2013.130195 · Cited by 23

Luteolin Inhibits Behavioral Sensitization by Blocking Methamphetamine-Induced MAPK Pathway Activation in the Caudate Putamen in Mice

Yan, T., Li, L., Sun, B., Liu, F., Yang, P., Chen, T., Li, T., & Liu, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098981 · Cited by 23

Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells

Calvo, N., Martín, M. J., de Boland, A. R., & Gentili, C. (2014) · Biochemistry and Cell Biology · doi:10.1139/bcb-2013-0106 · Cited by 23

Response of Adipose Tissue-Derived Stromal Cells in Tissue-Related O2 Microenvironment to Short-Term Hypoxic Stress

Andreeva, E. R., Lobanova, M. V., Udartseva, O. O., & Buravkova, L. B. (2014) · Cells Tissues Organs · doi:10.1159/000438921 · Cited by 22

JNK1 Derived from Orange-Spotted Grouper, Epinephelus coioides, Involving in the Evasion and Infection of Singapore Grouper Iridovirus (SGIV)

Guo, M., Wei, J., Huang, X., Zhou, Y., Yang, Y., & Qin, Q. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00121 · Cited by 23

Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding

McReynolds, A. C., Karra, A. S., Li, Y., Lopez, E. D., Turjanski, A. G., Dioum, E. M., Lorenz, K., Zaganjor, E., Stippec, S., McGlynn, K., et al. (2016) · Biochemistry · doi:10.1021/acs.biochem.6b00096 · Cited by 23

Extracellular Signal-Regulated Kinases (ERK) Inhibitors from Aristolochia yunnanensis

Cheng, Z., Shao, W., Liu, Y.-N., Liao, Q., Lin, T., Shen, X., & Yin, S. (2013) · Journal of Natural Products · doi:10.1021/np300887d · Cited by 23

A systems biology approach reveals new endoplasmic reticulum-associated targets for the correction of the ATP7B mutant causing Wilson disease

Concilli, M., Iacobacci, S., Chesi, G., Carissimo, A., & Polishchuk, R. (2016) · Metallomics · doi:10.1039/c6mt00148c · Cited by 23

A Screen for Key Genes and Pathways Involved in High-Quality Brush Hair in the Yangtze River Delta White Goat

Guo, H., Cheng, G., Li, Y., Zhang, H., & Qin, K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169820 · Cited by 23

S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells

Fan, Y., Mao, Y., Cao, S., Xia, G., Zhang, Q., Zhang, H., Qiu, F., & Kang, N. (2018) · Molecules · doi:10.3390/molecules23123175 · Cited by 23

MAP kinase modulation in squamous cell carcinoma of the oral cavity.

Aguzzi, A., Maggioni, D., Nicolini, G., Tredici, G., Gaini, R. M., & Garavello, W. (2009) · PubMed · Cited by 23

Hydrogen sulfide promotes osteogenic differentiation of human periodontal ligament cells via p38-MAPK signaling pathway under proper tension stimulation

Jiang, Z., & Hua, Y. (2016) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2016.08.008 · Cited by 23

Comparisons of two receptor-MAPK pathways in a single cell-type reveal mechanisms of signalling specificity

Ma, Y., Flückiger, I., Nicolet, J., Pang, J., Dickinson, J. B., Bellis, D. D., Emonet, A., Fujita, S., & Geldner, N. (2024) · Nature Plants · doi:10.1038/s41477-024-01768-y · Cited by 24

A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF

Bera, A., Das, F., Ghosh‐Choudhury, N., Li, X., Pal, S., Gorin, Y. C., Kasinath, B. S., Abboud, H. E., & Choudhury, G. G. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00387.2013 · Cited by 22

A ROS-dependent and Caspase-3-mediated apoptosis in sheep bronchial epithelial cells in response to Mycoplasma Ovipneumoniae infections

Xue, D., Li, Y., Jiang, Z., Deng, G., Li, M., Liu, X., & Wang, Y. (2017) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2017.04.004 · Cited by 22

The Pharmacological Inhibition of ERK5 Enhances Apoptosis in Acute Myeloid Leukemia Cells

Kang, C., Kim, J. S., Kim, C., Kim, E., & Chung, H. (2018) · International Journal of Stem Cells · doi:10.15283/ijsc18053 · Cited by 22

Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell

Lu, C., Zhou, R., He, Y., Meng, M., Hu, J., Liu, Y., Pan, Y., Tang, Z., & Yue, Z. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12181 · Cited by 23

MKK4 Inhibitors—Recent Development Status and Therapeutic Potential

Katzengruber, L., Sander, P., & Laufer, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087495 · Cited by 22

Overexpression of GNAO1 correlates with poor prognosis in patients with gastric cancer and plays a role in gastric cancer cell proliferation and apoptosis

Liu, Z., Zhang, J., Wu, L., Liu, J., & Zhang, M. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1598 · Cited by 22

The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia Therapy

Gocek, E., & Studzinski, G. P. (2015) · Journal of Clinical Medicine · doi:10.3390/jcm4040504 · Cited by 22

Knockdown of Sec8 enhances the binding affinity of c‐Jun N‐terminal kinase ( JNK )‐interacting protein 4 for mitogen‐activated protein kinase kinase 4 ( MKK 4) and suppresses the phosphorylation of MKK 4, p38, and JNK , thereby inhibiting apoptosis

Tanaka, T., Iino, M., & Goto, K. (2014) · FEBS Journal · doi:10.1111/febs.13063 · Cited by 22

MAPKs in development: insights from Dictyostelium signaling pathways

Hadwiger, J. A., & Nguyen, H. (2011) · BioMolecular Concepts · doi:10.1515/bmc.2011.004 · Cited by 24

A Ubiquitin E2 Variant Protein Acts in Axon Termination and Synaptogenesis in Caenorhabditis elegans

Trujillo, G., Nakata, K., Yan, D., MARUYAMA, I. N., & Jin, Y. (2010) · Genetics · doi:10.1534/genetics.110.117341 · Cited by 22

Gene of the month: BRAF

Govender, D., & Chetty, R. (2012) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2012-200960 · Cited by 22

Cannabinoid receptors are involved in the protective effect of a novel curcumin derivative C66 against CCl4-induced liver fibrosis

Huang, S., Chen, D., Wu, H., Chen, R., Du, S.-J., Dong, J., Liang, G., Xu, L., Wang, X., Yang, Y., et al. (2016) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2016.02.067 · Cited by 22

Surface Coatings Protect against the In vitro Toxicity of Zinc Oxide Nanoparticles in Human Hepatic Stellate Cells

Osmond-McLeod, M. J. (2014) · Journal of Nanomedicine & Nanotechnology · doi:10.4172/2157-7439.1000232 · Cited by 22

Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity

Sfyri, P. P., Yuldasheva, N. Y., Tzimou, A., Giallourou, N., Crispi, V., Aburima, A. A., Beltrán-Álvarez, P., Patel, K., Mougios, V., Swann, J. R., et al. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.10.422 · Cited by 22

Activation of reactive oxygen species-mediated mitogen-activated protein kinases pathway regulates both extrinsic and intrinsic apoptosis induced by arctigenin in Hep G2

Zheng, L., Zhou, H., Zhang, S., Dai, W., Zhang, Y., Hong, L., Chen, F., & Cao, J. (2019) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13180 · Cited by 22

The efficacy of Origanum majorana nanocubosomal systems in ameliorating submandibular salivary gland alterations in streptozotocin-induced diabetic rats

Farag, D. B. E., Yousry, C., Al-mahallawi, A. M., El‐Askary, H. I., Meselhy, M. R., & AbuBakr, N. (2021) · Drug Delivery · doi:10.1080/10717544.2021.2018522 · Cited by 26

MAP kinases have different functions in Dictyostelium G protein-mediated signaling

Nguyen, H., Raisley, B., & Hadwiger, J. A. (2010) · Cellular Signalling · doi:10.1016/j.cellsig.2010.01.008 · Cited by 22

Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells

Buzzi, N. S., Boland, R., & de Boland, A. R. (2010) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2010.05.009 · Cited by 22

Vinculin and Rab5 Complex Is Requited for Uptake of Staphyrococcus aureus and Interleukin-6 Expression

Hagiwara, M., Kokubu, E., Sugiura, S., Komatsu, T., Tada, H., Isoda, R., Tanigawa, N., Kato, Y., Ishida, N., Kobayashi, K., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087373 · Cited by 22

Mitogen‐ and stress‐activated protein kinase 1 modulates photic entrainment of the suprachiasmatic circadian clock

Cao, R., Butcher, G. Q., Karelina, K., Arthur, J. S. C., & Obrietan, K. H. (2012) · European Journal of Neuroscience · doi:10.1111/ejn.12028 · Cited by 22

Differential Roles of JNK, ERK1/2, and p38 Mitogen-Activated Protein Kinases on Endothelial Cell Tissue Repair Functions in Response to Tumor Necrosis Factor-α

Kanaji, N., Nelson, A. J., Wang, X., Sato, T., Nakanishi, M., Gunji, Y., Basma, H., Michalski, J., Farid, M., Rennard, S. I., et al. (2012) · Journal of Vascular Research · doi:10.1159/000345525 · Cited by 21

Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors

Ma, M., Bordignon, P., Dotto, G. P., & Pelet, S. B. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05574 · Cited by 20

Single-Cell Transcriptomic Profiling in Inherited Retinal Degeneration Reveals Distinct Metabolic Pathways in Rod and Cone Photoreceptors

Chen, Y., Dong, Y., Yan, J., Wang, L., Yu, S., Jiao, K., & Paquet‐Durand, F. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012170 · Cited by 21

Comparative transcriptomics reveals the immune dynamics during the molting cycle of swimming crab Portunus trituberculatus

Liu, M., Ni, H., Zhang, X., Sun, Q., Wu, X., & He, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1037739 · Cited by 21

MAP Kinase Cascades in Antigen Receptor Signaling and Physiology

Yasuda, T. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_481 · Cited by 21

Novel immunosuppressive agent c aerulomycin A exerts its effect by depleting cellular iron content

Kaur, S., Srivastava, G., Sharma, A. N., & Jolly, R. S. (2014) · British Journal of Pharmacology · doi:10.1111/bph.13051 · Cited by 22

Signaling to Extracellular Signal-regulated Kinase from ErbB1 Kinase and Protein Kinase C

Perrett, R. M., Fowkes, R. C., Caunt, C. J., Tsaneva-Atanasova, K. T., Bowsher, C. G., & McArdle, C. A. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.455345 · Cited by 21

The Non-Classical MAP Kinase ERK3 Controls T Cell Activation

Marquis, M., Boulet, S., Mathien, S., Rousseau, J., Thébault, P., Daudelin, J., Rooney, J., Turgeon, B., Beauchamp, C., Meloche, S., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086681 · Cited by 21

Induction of heme oxygenase-1 shifts the balance from proinjury to prosurvival in the placentas of pregnant rats with reduced uterine perfusion pressure

George, E. M., & Arany, I. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00617.2011 · Cited by 21

Genome-Wide Analysis of Host Responses to Four Different Types of Microorganisms inBombyx Mori(Lepidoptera: Bombycidae)

Cheng, T., Lin, P., Huang, L., Wu, Y., Jin, S., Liu, C., & Xia, Q. (2016) · Journal of Insect Science · doi:10.1093/jisesa/iew020 · Cited by 21

S -Equol, a Major Isoflavone from Soybean, Inhibits Nitric Oxide Production in Lipopolysaccharide-Stimulated Rat Astrocytes Partially via the GPR30-Mediated Pathway

Moriyama, M., Hashimoto, A., Satoh, H., Kawabe, K., Mizue, O., Takano, K., & Nakamura, Y. (2018) · International Journal of Inflammation · doi:10.1155/2018/8496973 · Cited by 21

Improvement of Photoaffinity SPR Imaging Platform and Determination of the Binding Site of p62/SQSTM1 to p38 MAP Kinase

Saito, A., Kawai, K., Takayama, H., SUDO, T., & Osada, H. (2008) · Chemistry - An Asian Journal · doi:10.1002/asia.200800099 · Cited by 21

Signaling Threshold Regulation by the Ras Effector IMP

Matheny, S. A., & White, M. A. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r800082200 · Cited by 21

MAP kinase phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease

Flach, R. J. R., & Bennett, A. M. (2010) · Aging · doi:10.18632/aging.100135 · Cited by 21

MAP3K8 (TPL2/COT) Affects Obesity-Induced Adipose Tissue Inflammation without Systemic Effects in Humans and in Mice

Ballak, D. B., van Essen, P., van Diepen, J. A., Jansen, H., Hijmans, A., Matsuguchi, T., Sparrer, H., Tack, C. J., Netea, M. G., Joosten, L. A. B., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089615 · Cited by 20

RAF1 mediates the FSH signaling pathway as a downstream molecule to stimulate estradiol synthesis and secretion in mouse ovarian granulosa cells

Luo, X., Liu, H., Guo, H., Sun, L., Gou, K., & Cui, S. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-393 · Cited by 20

Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice

Kang, Z., Yang, M., Liu, Y., Yang, G., Dong, Y., Zhou, H., Zhang, Z., Li, M., Fan, H., Li, Z., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60123-7 · Cited by 21

1,25(OH)2D3 inhibits high glucose-induced apoptosis and ROS production in human peritoneal mesothelial cells via the MAPK/P38 pathway

Yang, L., Wu, L., Du, S., HU, Y., Fan, Y., & Ma, J. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5323 · Cited by 20

Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway

Guo, K. Y., Han, L., Li, X., Yang, A. V., Lu, J., Guan, S., Li, H., Yu, Y., Zhao, Y., Yang, J., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.23166 · Cited by 20

Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

Dong, Q., Kuefner, M., Deng, X., Bridges, D., Park, E. A., Elam, M. B., & Raghow, R. (2018) · Biology of Sex Differences · doi:10.1186/s13293-018-0202-x · Cited by 20

DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway

Luo, J., Xue, D., Song, F., Liu, X., Li, W., & Wang, Y. (2020) · Molecular Immunology · doi:10.1016/j.molimm.2020.07.019 · Cited by 21

Elucidation of Abnormal Extracellular Regulated Kinase (ERK) Signaling and Associations with Syndromic and Non-syndromic Autism

Tiwari, A., Rahi, S., & Mehan, S. (2020) · Current Drug Targets · doi:10.2174/1389450121666201020155010 · Cited by 19

Molecular regulation of autophagy in a pro-inflammatory tumour microenvironment: New insight into the role of serum amyloid A

du Plessis, M., Davis, T., Loos, B., Pretorius, E., de Villiers, W. J. S., & Engelbrecht, A. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.01.007 · Cited by 20

MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength

Hoerndli, F. J., Brockie, P. J., Wang, R., Mellem, J. E., Kallarackal, A. J., Doser, R. L., Pierce, D. M., Madsen, D. M., & Maricq, A. V. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110577 · Cited by 22

miR‐181b regulates vascular endothelial aging by modulating an MAP3K3 signaling pathway

Zhou, H., Yang, D., Cheng, H. S., McCoy, M. G., Pérez‐Cremades, D., Haemmig, S., Wong, D., Chen, L., & Feinberg, M. W. (2022) · The FASEB Journal · doi:10.1096/fj.202200046r · Cited by 21

Cell-cycle arrest and mitochondria-dependent apoptosis induction in T-47D cells by the capsular polysaccharide from the marine bacterium Kangiella japonica KMM 3897

Kuzmich, A. S., Romanenko, L. A., & Kokoulin, M. S. (2023) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2023.121237 · Cited by 20

Gα16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS)

Liu, A. M. F., Lo, R. K. H., Lee, M. M. K., Wang, Y., Yeung, W. W. S., Ho, M. K. C., Su, Y. L., Ye, R. D., & Wong, Y. H. (2010) · Cellular Signalling · doi:10.1016/j.cellsig.2010.05.013 · Cited by 20

p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes

Siljamäki, E., Raiko, L., Toriseva, M., Nissinen, L. M., Näreoja, T., Peltonen, J. T. K., Kähäri, V., & Peltonen, S. A. (2013) · Archives of Dermatological Research · doi:10.1007/s00403-013-1391-0 · Cited by 20

p53 and mitogen-activated protein kinase pathway protein profiles in fresh and frozen spermatozoa

Karabulut, S., Demiroglu‐Zergeroglu, A., Yilmaz, E. S., Sağır, F., & Delikara, N. (2013) · Andrologia · doi:10.1111/and.12200 · Cited by 20

Dynamic Localization of Fus3 Mitogen-Activated Protein Kinase Is Necessary To Evoke Appropriate Responses and Avoid Cytotoxic Effects

Chen, R. E., Patterson, J. C., Goupil, L. S., & Thorner, J. W. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00361-10 · Cited by 21

Activation of MEK1/2‐ERK1/2 signaling during NNK‐induced lung carcinogenesis in female A/J mice

Yamakawa, K., Yokohira, M., Nakano, Y., Kishi, S., Kanie, S., & Imaida, K. (2016) · Cancer Medicine · doi:10.1002/cam4.652 · Cited by 20

Protective function of pyridoxamine on retinal photoreceptor cells via activation of the p-Erk1/2/Nrf2/Trx/ASK1 signalling pathway in diabetic mice

Ren, X. S., Sun, H., Zhang, C., Li, C., Wang, J., Shen, J., YU, D., & Kong, L. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5270 · Cited by 20

Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest

Konson, A., Pradeep, S., D’Acunto, C. W., & Seger, R. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000492990 · Cited by 20

Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation

Nadel, G., Yao, Z., Ben-Ami, I., Naor, Z., & Seger, R. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000493963 · Cited by 20

Role of Rac1-regulated signaling in medulloblastoma invasion

Zavarella, S. M., Nakada, M., Belverud, S. A., Coniglio, S. J., Chan, A. Y., Mittler, M. A., Schneider, S. J., & Symons, M. H. (2009) · Journal of Neurosurgery Pediatrics · doi:10.3171/2009.4.peds08322 · Cited by 20

Magnesium deprivation inhibits a MEK–ERK cascade and cell proliferation in renal epithelial Madin-Darby canine kidney cells

Ikari, A., Atomi, K., Kinjo, K., Sasaki, Y., & Sugatani, J. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.03.016 · Cited by 20

ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1

Bardwell, A. J., Wu, B., Sarin, K. Y., Waterman, M. L., Atwood, S. X., & Bardwell, L. (2022) · Life Science Alliance · doi:10.26508/lsa.202101353 · Cited by 20

Activation of extracellular signal-regulated kinase signaling in the pedunculopontine tegmental cells is involved in the maintenance of sleep in rats

Désarnaud, F., Macone, B. W., & Datta, S. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07146.x · Cited by 20

C1QTNF6 as a novel biomarker regulates cellular behaviors in A549 cells and exacerbates the outcome of lung adenocarcinoma patients

Han, M., Wang, B., Zhu, M., & Zhang, Y. (2019) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-019-00377-w · Cited by 19

Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function

Kostenko, S., Shiryaev, A., Gerits, N., Dumitriu, G., Klenow, H. B., Johannessen, M., & Moens, U. L. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0496-2 · Cited by 17

The Dictyostelium MAPK ERK1 is phosphorylated in a secondary response to early developmental signaling

Schwebs, D. J., & Hadwiger, J. A. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.10.009 · Cited by 19

MAPK Phosphatase-2 (MKP-2) Is Induced by hCG and Plays a Role in the Regulation of CYP11A1 Expression in MA-10 Leydig Cells

Gomez, N. V., Gorostizaga, A., Garcia, M. M. M. S., Brion, L., Acquier, A. B., González-Calvar, S. I., Méndez, C. F., Podesta, E. J., & Paz, C. (2013) · Endocrinology · doi:10.1210/en.2012-2032 · Cited by 20

Role of host-encoded proteins in restriction of retroviral integration

Suzuki, Y., Chew, M. L., & Suzuki, Y. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00227 · Cited by 25

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