Differential regulation and properties of MAPKs

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

Johnson, G. L., & Lapadat, R. (2002) · Science · doi:10.1126/science.1072682 · Cited by 4,295

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

Kyriakis, J. M., & Avruch, J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.807 · Cited by 3,400

A central role for JNK in obesity and insulin resistance

Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature · doi:10.1038/nature01137 · Cited by 3,359

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Lee, J. C., Laydon, J. T., McDonnell, P., Gallagher, T. F., Kumar, S., Green, D., McNulty, D. E., Blumenthal, M. J., Keys, J., vatter, S. W. L., et al. (1994) · Nature · doi:10.1038/372739a0 · Cited by 3,266

Protein Tyrosine Phosphatases in the Human Genome

Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J., & Mustelin, T. (2004) · Cell · doi:10.1016/j.cell.2004.05.018 · Cited by 1,886

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Hibi, M., Lin, A., Smeal, T., Minden, A., & Karin, M. (1993) · Genes & Development · doi:10.1101/gad.7.11.2135 · Cited by 1,886

Signal Transduction through MAP Kinase Cascades

Lewis, T. S., Shapiro, P. S., & Ahn, N. G. (1998) · Advances in cancer research · doi:10.1016/s0065-230x(08)60765-4 · Cited by 1,759

LPA rescues ER stress‐associated apoptosis in hypoxia and serum deprivation‐stimulated mesenchymal stem cells

Li, Z., Wei, H., Liu, X., Hu, S., Cong, X., & Chen, X. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22731 · Cited by 36

Tissue-type Plasminogen Activator (tPA) Promotes M1 Macrophage Survival through p90 Ribosomal S6 Kinase (RSK) and p38 Mitogen-activated Protein Kinase (MAPK) Pathway

Lin, L., Jin, Y., & Hu, K. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.599688 · Cited by 35

The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension

Roberts, R. E. (2012) · Journal of Experimental Pharmacology · doi:10.2147/jep.s28907 · Cited by 36

The Temporal Pattern of Stimulation Determines the Extent and Duration of MAPK Activation in a Caenorhabditis elegans Sensory Neuron

Tomida, T., Oda, S., Takekawa, M., Iino, Y., & Saito, H. (2012) · Science Signaling · doi:10.1126/scisignal.2002983 · Cited by 36

Negative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic Responses

Altman, J. K., Glaser, H., Sassano, A., Joshi, S. S., Ueda, T., Watanabe‐Fukunaga, R., Fukunaga, R., Tallman, M. S., & Platanias, L. C. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.064642 · Cited by 36

High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

Dada, L. A., Bittar, H. E. T., Welch, L. C., Vagin, O., Deiss‐Yehiely, N., Kelly, A. M., Baker, M. R., Capri, J. R., Cohn, W., Whitelegge, J. P., et al. (2015) · Molecular and Cellular Biology · doi:10.1128/mcb.00813-15 · Cited by 35

β 2 -receptor agonists salbutamol and terbutaline attenuated cytokine production by suppressing ERK pathway through cAMP in macrophages

Keränen, T., Hömmö, T., Moilanen, E., & Korhonen, R. (2017) · Cytokine · doi:10.1016/j.cyto.2016.07.016 · Cited by 36

Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts

Kunimatsu, R., Gunji, H., Tsuka, Y., Yoshimi, Y., Awada, T., Sumi, K., Nakajima, K., Kimura, A., Hiraki, T., Abe, T., et al. (2018) · Lasers in Medical Science · doi:10.1007/s10103-017-2426-0 · Cited by 36

Activation loop phosphorylation of ERK3 is important for its kinase activity and ability to promote lung cancer cell invasiveness

Elkhadragy, L., Alsaran, H., Morel, M., & Long, W. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.003699 · Cited by 36

Neuronal MAP kinase p38α inhibits c-Jun N-terminal kinase to modulate anxiety-related behaviour

Stefanoska, K., Bertz, J., Volkerling, A. M., van der Hoven, J., Ittner, L. M., & Ittner, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-32592-y · Cited by 37

Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis

Zhou, R.-S., Wang, X., Sun, Q., Ye, Z. J., Liu, J., Zhou, D.-H., & Tang, Y. C. (2019) · BioMed Research International · doi:10.1155/2019/3065818 · Cited by 36

METTL3-Mediated lncRNA m6A Modification in the Osteogenic Differentiation of Human Adipose-Derived Stem Cells Induced by NEL-Like 1 Protein

Song, Y., Pan, Y., Wu, M., Sun, W., Luo, L., Zhao, Z., & Liu, J. (2021) · Stem Cell Reviews and Reports · doi:10.1007/s12015-021-10245-4 · Cited by 36

Penehyclidine hydrochloride ameliorates renal ischemia–reperfusion injury in rats

Wang, Y., Li, G., Ma, L., Zheng, Y., Zhang, S., Zhang, H., Qiu, M. R., & Ma, X. (2013) · Journal of Surgical Research · doi:10.1016/j.jss.2013.07.041 · Cited by 36

Fibromodulin Suppresses Nuclear Factor-κB Activity by Inducing the Delayed Degradation of IKBA via a JNK-dependent Pathway Coupled to Fibroblast Apoptosis

Lee, Y.-H., & Schiemann, W. P. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.168682 · Cited by 36

Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 as a Neuroprotective Agent: Promotion of the Morphological Development of Midbrain Dopaminergic Neurons

Collins, L., O’Keeffe, G. W., Long-Smith, C. M., Wyatt, S. L., Sullivan, A. M., Toulouse, A., & Nolan, Y. M. (2013) · NeuroMolecular Medicine · doi:10.1007/s12017-013-8230-5 · Cited by 36

The Kidney Vero-E6 Cell Line: A Suitable Model to Study the Toxicity of Microcystins

Menezes, C., Valério, E., & Dias, E. M. (2013) · InTech eBooks · doi:10.5772/54463 · Cited by 36

Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes

Dinner, S., Kaltschmidt, J., Stump-Guthier, C., Hetjens, S., Ishikawa, H., Tenenbaum, T., Schroten, H., & Schwerk, C. (2016) · Microbes and Infection · doi:10.1016/j.micinf.2016.09.003 · Cited by 36

Dual Specificity Phosphatase 5‐Substrate Interaction: A Mechanistic Perspective

Kutty, R. G., Talipov, M. R., Bongard, R. D., Jones, R. A., Sweeney, N. L., Sem, D. S., Rathore, R., & Ramchandran, R. (2017) · Comprehensive physiology · doi:10.1002/cphy.c170007 · Cited by 38

Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Corneal Endothelial Cell Proliferation

Nakahara, M., Okumura, N., Nakano, S., & Koizumi, N. (2018) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.18-24394 · Cited by 30

The Role of Intracellular Calcium for the Development and Treatment of Neuroblastoma

Satheesh, N. J., & Büsselberg, D. (2015) · Cancers · doi:10.3390/cancers7020811 · Cited by 34

Time-Dependent Modulation of Mitogen Activated Protein Kinases and AKT in Rat Hippocampus and Cortex in the Pilocarpine Model of Epilepsy

Lopes, M. W., Soares, F. M. S., de Mello, N., Nunes, J. C., de Córdova, F. M., Walz, R., & Leal, R. B. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0797-y · Cited by 35

Regulation of the Ras‐GTPase activating protein neurofibromin by C‐tail phosphorylation: implications for protein kinase C/Ras/extracellular signal‐regulated kinase 1/2 pathway signaling and neuronal differentiation

Leondaritis, G., Petrikkos, L., & Mangoura, D. A. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05975.x · Cited by 37

Tetramethylpyrazine Suppresses Transient Oxygen-Glucose Deprivation-Induced Connexin32 Expression and Cell Apoptosis via the ERK1/2 and p38 MAPK Pathway in Cultured Hippocampal Neurons

Gong, G., Yuan, L., Cai, L., Ran, M., Zhang, Y., Gong, H., Dai, X., Wu, W. H., & Dong, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105944 · Cited by 35

Lipin1 Regulates Skeletal Muscle Differentiation through Extracellular Signal-regulated Kinase (ERK) Activation and Cyclin D Complex-regulated Cell Cycle Withdrawal

Jiang, W., Zhu, J., Zhuang, X., Zhang, X., Luo, T., Esser, K. A., & Ren, H. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.686519 · Cited by 35

ERK Signals: Scaffolding Scaffolds?

Casar, B., & Crespo, P. (2016) · Front. Cell Dev. Biol. · doi:10.3389/fcell.2016.00049 · Cited by 34

Preventive effects of dietary walnuts on high-fat-induced hepatic fat accumulation, oxidative stress and apoptosis in mice

Choi, Y., Abdelmegeed, M. A., & Song, B. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.08.013 · Cited by 35

Targeting ERK beyond the boundaries of the kinase active site in melanoma

Sammons, R. M., Ghose, R., Tsai, K. Y., & Dalby, K. N. (2019) · Molecular Carcinogenesis · doi:10.1002/mc.23047 · Cited by 37

E2F4 functions as a tumour suppressor in acute myeloid leukaemia via inhibition of the MAPK signalling pathway by binding to EZH2

Feng, Y., Li, L., Du, Y. Z., Peng, X., & Chen, F. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14853 · Cited by 37

WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway

Zhou, B., Wang, D., Feng, X., Zhang, Y., Wang, Y., Zhuang, J., Zhang, X., Chen, G., Delpire, E. J., Gu, D., et al. (2011) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00032.2011 · Cited by 35

Gastrointestinal Microbiome Dysbiosis in Infant Mice Alters Peripheral CD8+ T Cell Receptor Signaling

González‐Pérez, G., & Lamousé-Smith, E. S. N. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00265 · Cited by 34

Nanotechnology‐mediated photodynamic therapy: Focus on overcoming tumor hypoxia

Moloudi, K., Abrahamse, H., & George, B. P. A. (2023) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1937 · Cited by 34

Cysteinyl‐leukotrienes induce vascular endothelial growth factor production in human monocytes and bronchial smooth muscle cells

Poulin, S., Thompson, C., Thivierge, M., Véronneau, S., McMahon, S., Dubois, C. M., Staňková, J., & Rola‐Pleszczynski, M. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2010.03653.x · Cited by 36

Evidence for the Involvement of p38 MAPK Activation in Barnacle Larval Settlement

He, L., Xu, Y., Matsumura, K., Zhang, Y., Zhang, G., Qi, S.-H., & Qian, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047195 · Cited by 34

Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in Neuroblastoma

DeNardo, B. D., Holloway, M. P., Ji, Q., Nguyen, K. T., Cheng, Y., Valentine, M. B., Salomon, A. R., & Altura, R. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082513 · Cited by 34

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

Chen, D., Chuang, H., Lan, J., Chen, Y., Hung, W., Lai, K., & Tan, T. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-84 · Cited by 34

Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1

Lai, S., & Pelech, S. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-07-0527 · Cited by 36

Double-Sided Personality: Effects of Arsenic Trioxide on Inflammation

Zhang, J., Zhang, Y., Wang, W., Li, C., & Zhang, Z. (2018) · Inflammation · doi:10.1007/s10753-018-0775-x · Cited by 34

Protocatechuic acid attenuates angiotensin II‐induced cardiac fibrosis in cardiac fibroblasts through inhibiting the NOX4/ROS/p38 signaling pathway

Song, H., & Ren, J. (2019) · Phytotherapy Research · doi:10.1002/ptr.6435 · Cited by 34

Identification of copper death-associated molecular clusters and immunological profiles in rheumatoid arthritis

Zhou, Y., Li, X., Ng, L., Zhao, Q. C., Guo, W., Hu, J., Zhong, J., Su, W., Liu, C., & Su, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1103509 · Cited by 34

uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells

Alapati, K., Kesanakurti, D., Rao, J. S., & Dasari, V. R. (2014) · Stem Cell Research · doi:10.1016/j.scr.2014.02.008 · Cited by 34

Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium

Fujiki, K., Inamura, H., & Matsuoka, M. (2013) · Archives of Toxicology · doi:10.1007/s00204-013-1077-6 · Cited by 34

Targeting Raf/MEK/ERK pathway in pituitary adenomas

Zhang, S., Feng, W., Dongsheng, G., & Lei, T. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.11.002 · Cited by 35

Naturally occurring asteriscunolide A induces apoptosis and activation of mitogen‐activated protein kinase pathway in human tumor cell lines

Negrín, G., Eiroa, J. L., Morales, M., Triana, J., Quintana, J., & Estévez, F. (2010) · Molecular Carcinogenesis · doi:10.1002/mc.20629 · Cited by 34

Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5

Kostenko, S., Dumitriu, G., & Moens, U. L. (2012) · Journal of Molecular Signaling · doi:10.1186/1750-2187-7-9 · Cited by 38

Ligand-Directed Signaling: 50 Ways to Find a Lover

Michel, M. C., & Alewijnse, A. E. (2007) · Molecular Pharmacology · doi:10.1124/mol.107.040923 · Cited by 34

Inflammation-related signaling pathways in tendinopathy

Jiang, L., Liu, T., Lyu, K., Chen, Y., Lu, J., Wang, X., Long, L., & Li, S. (2023) · Open Life Sciences · doi:10.1515/biol-2022-0729 · Cited by 37

Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy

Jaiman, S., Sharma, A. K., Singh, K., & Khanna, D. (2013) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-013-1568-7 · Cited by 33

MKK6 is Upregulated in Human Esophageal, Stomach, and Colon Cancers

Parray, A. A., Baba, R. A., Bhat, H. F., Wani, L. A., Mokhdomi, T. A., Mushtaq, U., Bhat, S. S., Kirmani, D., Kuchay, S., Wani, M. M., et al. (2014) · Cancer Investigation · doi:10.3109/07357907.2014.933236 · Cited by 33

Differential phosphorylation-based regulation of αB-crystallin chaperone activity for multipass transmembrane proteins

Ciano, M., Allocca, S., Ciardulli, M. C., della Volpe, L., Bonatti, S., & D’Agostino, M. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.09.071 · Cited by 33

MKK4 from Litopenaeus vannamei is a regulator of p38 MAPK kinase and involved in anti-bacterial response

Wang, S., Yin, B., Li, H., Xiao, B., Lǚ, K., Feng, C., He, J., & Li, C. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.09.015 · Cited by 33

The direct effect of lobeglitazone, a new thiazolidinedione, on pancreatic beta cells: A comparison with other thiazolidinediones

Kwon, M. J., Lee, Y., Jung, H. S., Shin, H. M., Kim, T. N., Lee, S. H., Rhee, B. D., Kim, M.-K., & Park, J. H. (2019) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2019.04.006 · Cited by 34

Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways

Hu, Z., Wang, H., Fu, Y., Ma, K., Ma, X., & Wang, J. (2020) · Nutrition and Cancer · doi:10.1080/01635581.2020.1801777 · Cited by 33

Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells: A systematic review and meta-analysis of in vitro and in vivo data

Faramarzi, F., Alimohammadi, M., Rahimi, A. A. R., Alizadeh‐Navaei, R., Jafari-Shakib, R., & Rafiei, A. (2022) · Nutrition Research · doi:10.1016/j.nutres.2022.05.003 · Cited by 33

T cells: an emerging cast of roles in bipolar disorder

Chen, Z., Huang, Y., Wang, B., Peng, H., Wang, X., Wu, H., Chen, W., & Wang, M. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02445-y · Cited by 35

Nuclear Envelope Regulation of Signaling Cascades

Choi, J. C., & Worman, H. J. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4899-8032-8_9 · Cited by 34

Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons

Ramiro-Cortés, Y., & Morán, J. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.05.015 · Cited by 33

Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC-7901 gastric cancer cells through the ERK signaling pathway

Liu, Y., Zhao, Y., JU, S., & Guo, L. (2014) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2014.2038 · Cited by 33

Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/orc-junNH2-terminal MAPK but not extracellular signal-regulated kinases-1/2

Binet, F., & Girard, D. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0708421 · Cited by 33

Global Regulation of a Differentiation MAPK Pathway in Yeast

Chavel, C. A., Caccamise, L. M., Li, B., & Cullen, P. J. (2014) · Genetics · doi:10.1534/genetics.114.168252 · Cited by 30

Resting and Active States of the ERK2:HePTP Complex

Francis, D. M., Różycki, B., Tortajada, A., Hummer, G., Peti, W., & Page, R. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2075136 · Cited by 32

Hedgehog signalling pathway inhibitors as cancer suppressing agents

Trinh, T. N., McLaughlin, E. A., Gordon, C. P., & McCluskey, A. (2013) · MedChemComm · doi:10.1039/c3md00334e · Cited by 32

Nucleus‐localized 21.5‐kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane‐associated 18.5‐kDa isoform

Smith, G. S. T., Samborska, B., Hawley, S. P., Klaiman, J. M., Gillis, T. E., Jones, N., Boggs, J. M., & Harauz, G. (2012) · Journal of Neuroscience Research · doi:10.1002/jnr.23166 · Cited by 32

MEKK3 Regulates IFN-γ Production in T Cells through the Rac1/2-Dependent MAPK Cascades

Wang, X., Zhang, F., Chen, F., Liu, D., Zheng, Y., Zhang, Y., Dong, C., & Su, B. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1002127 · Cited by 32

Glycoarray Technologies: Deciphering Interactions from Proteins to Live Cell Responses

Puvirajesinghe, T. M., & Turnbull, J. E. (2016) · Microarrays · doi:10.3390/microarrays5010003 · Cited by 33

CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45

Huang, W., Kuo, Y.-H., Kuo, H., Hsieh, M., Huang, C.-Y., Lee, K., Lee, K.-F., Shen, C., Tung, S., & Teng, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0168989 · Cited by 32

Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields

Altun, G., Kaplan, S., Deniz, Ö. G., Kocacan, S. E., Canan, S., Davis, D. L., & Marangoz, C. (2017) · Journal of Microscopy and Ultrastructure · doi:10.1016/j.jmau.2017.05.006 · Cited by 32

Sesquiterpene coumarins from Ferula sinkiangensis K.M.Shen and their cytotoxic activities

Wang, J., Wang, H., Zhang, M., Li, X., Zhao, Y., Chen, G., Si, J., & Jiang, L. (2020) · Phytochemistry · doi:10.1016/j.phytochem.2020.112531 · Cited by 32

Protective effect of selegiline on cigarette smoke-induced oxidative stress and inflammation in rat lungs in vivo

Cui, Y., Liu, K. W. K., Ip, M., Liang, Y., & Mak, J. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-2426 · Cited by 32

Acer tataricum subsp. ginnala Inhibits Skin Photoaging via Regulating MAPK/AP-1, NF-κB, and TGFβ/Smad Signaling in UVB-Irradiated Human Dermal Fibroblasts

Jin, Y.-J., Ji, Y., Jang, Y. P., & Choung, S. (2021) · Molecules · doi:10.3390/molecules26030662 · Cited by 33

Mesenchymal Stem Cell-Derived Exosomal MiRNAs Promote M2 Macrophages Polarization: Therapeutic Opportunities for Spinal Cord Injury

Liang, Z., Xu, X., Rao, J., Yang, Z., Wang, C., & Chen, C. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.926928 · Cited by 34

Muscarinic receptors prevent oxidative stress‐mediated apoptosis induced by domoic acid in mouse cerebellar granule cells

Giordano, G., Li, L., White, C. C., Farin, F. M., Wilkerson, H.-W., Kavanagh, T. J., & Costa, L. G. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05969.x · Cited by 32

Arsenic trioxide induces cardiac fibroblast apoptosis in vitro and in vivo by up-regulating TGF-β1 expression

Cui, L., Qu, X., Xu, W., Qu, N., Mei, L., Liu, Y., Wang, X., Yu, X., Liu, Z., Nie, D., et al. (2013) · Toxicology Letters · doi:10.1016/j.toxlet.2013.03.024 · Cited by 32

Akt cross-links IL-4 priming, stem cell factor signaling, and IgE-dependent activation in mature human mast cells

Feuser, K., Feilhauer, K., Staib, L., Bischoff, S. C., & Lorentz, A. (2010) · Molecular Immunology · doi:10.1016/j.molimm.2010.10.010 · Cited by 32

Resistance of stem‐like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents

Vangipuram, S. D., Wang, Z. J., & Lyman, W. D. (2009) · Pediatric Blood & Cancer · doi:10.1002/pbc.22351 · Cited by 33

Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cells

Majumdar, G., Adris, P., Bhargava, N., Chen, H., & Raghow, R. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-709 · Cited by 32

Phosphorylation and Stabilization of Topoisomerase IIα Protein by p38γ Mitogen-activated Protein Kinase Sensitize Breast Cancer Cells to Its Poisons

Qi, X.-M., Hou, S., Lepp, A., Li, R., Basir, Z., Lou, Z., & Chen, G. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.229260 · Cited by 33

Proapoptotic Ginsenosides Compound K and Rh2 Enhance Fas-induced Cell Death of Human Astrocytoma Cells Through Distinct Apoptotic Signaling Pathways

Choi, K., & Choi, C. (2009) · Cancer Research and Treatment · doi:10.4143/crt.2009.41.1.36 · Cited by 32

MEK–ERK and heparin‐susceptible signaling pathways are involved in cell‐cycle entry of the wound edge retinal pigment epithelium cells in the adult newt

Yoshikawa, T., Mizuno, A., Yasumuro, H., Inami, W., Vergara, M. N., Del Rio‐Tsonis, K., & Chiba, C. (2012) · Pigment Cell & Melanoma Research · doi:10.1111/j.1755-148x.2011.00935.x · Cited by 31

Current Understanding of the Role of Adenosine Receptors in Cancer

Venugopala, K. N., & Buccioni, M. (2024) · Molecules · doi:10.3390/molecules29153501 · Cited by 35

Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma

Gavine, P. R., Wang, M., Yu, D., Hu, E., Huang, C., Xia, J., Su, X., Fan, J., Zhang, T., Ye, Q., et al. (2015) · BMC Cancer · doi:10.1186/s12885-015-1455-y · Cited by 31

CAPE promotes TRAIL-induced apoptosis through the upregulation of TRAIL receptors via activation of p38 and suppression of JNK in SK-Hep1 hepatocellular carcinoma cells

Kim, E. Y., Ryu, J., & Kim, A. K. (2013) · International Journal of Oncology · doi:10.3892/ijo.2013.2018 · Cited by 31

MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade

Cai, Q., Zhou, W., Wang, W., Dong, B., Han, D., Shen, T., Creighton, C. J., Moore, D. D., & Yang, F. (2021) · Science Advances · doi:10.1126/sciadv.abi6439 · Cited by 32

p38γ Mitogen-activated Protein Kinase Signals through Phosphorylating Its Phosphatase PTPH1 in Regulating Ras Protein Oncogenesis and Stress Response

Hou, S., Suresh, P. S., Qi, X.-M., Lepp, A., Mirza, S. P., & Chen, G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.335794 · Cited by 31

Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding

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