Estimation of autistic children by metallomics analysis

Autism as a strongly genetic disorder: evidence from a British twin study

Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., & Rutter, M. (1995) · Psychological Medicine · doi:10.1017/s0033291700028099 · Cited by 2,461 · see citing works

Functional impact of global rare copy number variation in autism spectrum disorders

Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., et al. (2010) · Nature · doi:10.1038/nature09146 · Cited by 2,013 · cited 2× · see citing works

Structural Variation of Chromosomes in Autism Spectrum Disorder

Marshall, C. R., Noor, A., Vincent, J. B., Lionel, A. C., Feuk, L., Skaug, J., Shago, M., Moessner, R., Pinto, D., Ren, Y., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.12.009 · Cited by 1,815 · see citing works

The Essential Toxin: Impact of Zinc on Human Health

Plum, L. M., Rink, L., & Haase, H. (2010) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph7041342 · Cited by 1,577 · see citing works

TOXIC AND ESSENTIAL METAL INTERACTIONS

Goyer, R. A. (1997) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.17.1.37 · Cited by 795 · see citing works

Pervasive Developmental Disorders in Preschool Children: Confirmation of High Prevalence

Chakrabarti, S., & Fombonne, E. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.6.1133 · Cited by 791 · see citing works

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

Lichten, L. A., & Cousins, R. J. (2009) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-033009-083312 · Cited by 732 · see citing works

Prenatal environmental exposures, epigenetics, and disease

Perera, F. P., & Herbstman, J. B. (2011) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.12.055 · Cited by 642 · see citing works

Metal and metalloid multi-elementary ICP-MS validation in whole blood, plasma, urine and hair

Goullé, J., Mahieu, L., Castermant, J., Neveu, N., Bonneau, L., Lainé, G., Bouige, D., & Lacroix, C. (2005) · Forensic Science International · doi:10.1016/j.forsciint.2005.04.020 · Cited by 637 · see citing works

Cadmium is a mutagen that acts by inhibiting mismatch repair

Jin, Y. H., Clark, A. B., Slebos, R. J. C., Al-Refai, H., Taylor, J. A., Kunkel, T. A., Resnick, M. A., & Gordenin, D. A. (2003) · Nature Genetics · doi:10.1038/ng1172 · Cited by 473 · see citing works

Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation

Takiguchi, M., Achanzar, W. E., Qu, W., Li, G., & Waalkes, M. P. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(03)00062-4 · Cited by 457 · see citing works

Epigenetic mechanisms in neurological disease

Jakovcevski, M., & Akbarian, S. (2012) · Nature Medicine · doi:10.1038/nm.2828 · Cited by 450 · see citing works

Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium

Arita, A., & Costa, M. (2009) · Metallomics · doi:10.1039/b903049b · Cited by 388 · see citing works

Level of Trace Elements (Copper, Zinc, Magnesium and Selenium) and Toxic Elements (Lead and Mercury) in the Hair and Nail of Children with Autism

Priya, M. D. L., & Geetha, A. (2010) · Biological Trace Element Research · doi:10.1007/s12011-010-8766-2 · Cited by 340 · see citing works

Human genetics illuminates the paths to metabolic disease

O’Rahilly, S. (2009) · Nature · doi:10.1038/nature08532 · Cited by 324 · see citing works

Impact of the Discovery of Human Zinc Deficiency on Health

Prasad, A. S. (2009) · Journal of the American College of Nutrition · doi:10.1080/07315724.2009.10719780 · Cited by 320 · see citing works

Pregnancy increases mobilization of lead from maternal skeleton

Gulson, B. L., Jameson, C. W., Mahaffey, K. R., Mizon, K. J., Korsch, M. J., & Vimpani, G. (1997) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(97)90058-5 · Cited by 319 · see citing works

Are Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder Different Manifestations of One Overarching Disorder? Cognitive and Symptom Evidence From a Clinical and Population-Based Sample

van der Meer, J. M. J., Oerlemans, A. M., van Steijn, D. J., Lappenschaar, M. G. A., de Sonneville, L. M. J., Buitelaar, J. K., & Rommelse, N. N. J. (2012) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.08.024 · Cited by 303 · see citing works

The prevalence puzzle: Autism counts

Weintraub, K. (2011) · Nature · doi:10.1038/479022a · Cited by 234 · see citing works

The Adaptive Response to Dietary Zinc in Mice Involves the Differential Cellular Localization and Zinc Regulation of the Zinc Transporters ZIP4 and ZIP5

Dufner‐Beattie, J., Kuo, Y., Gitschier, J. M., & Andrews, G. K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m409962200 · Cited by 220 · see citing works

The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders

Faber, S., Zinn, G. M., Kern, J. C., & Kingston, H. M. (2009) · Biomarkers · doi:10.1080/13547500902783747 · Cited by 200 · see citing works

Cancer, cadmium and genome integrity

McMurray, C. T., & Tainer, J. A. (2003) · Nature Genetics · doi:10.1038/ng0703-239 · Cited by 195 · see citing works

Toxic trace elements in the hair of children with autism

Fido, A. A., & Al-Saad, S. (2005) · Autism · doi:10.1177/1362361305053255 · Cited by 194 · see citing works

Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: A double blind and randomized trial [ISRCTN64132371]

Akhondzadeh, S., Mohammadi, M.-R., & Khademi, M. (2004) · BMC Psychiatry · doi:10.1186/1471-244x-4-9 · Cited by 186 · see citing works

Infantile zinc deficiency: Association with autism spectrum disorders

Yasuda, H., Yoshida, K., Yasuda, Y., & Tsutsui, T. (2011) · Scientific Reports · doi:10.1038/srep00129 · Cited by 185 · see citing works

Application of double focusing sector field ICP-MS for multielemental characterization of human hair and nails. Part I. Analytical methodology

Rodushkin, I., & Axelsson, M. D. (2000) · The Science of The Total Environment · doi:10.1016/s0048-9697(00)00369-7 · Cited by 158 · see citing works

Analyses of toxic metals and essential minerals in the hair of Arizona children with autism and associated conditions, and their mothers

Adams, J. B., Holloway, C. E., George, F., & Quig, D. (2006) · Biological Trace Element Research · doi:10.1385/bter:110:3:193 · Cited by 154 · see citing works

Zinc in Attention-Deficit/Hyperactivity Disorder

Arnold, L. E., & DiSilvestro, R. A. (2005) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2005.15.619 · Cited by 149 · see citing works

Serum Zinc Correlates with Parent- and Teacher- Rated Inattention in Children with Attention-Deficit/Hyperactivity Disorder

Arnold, L. E., Bozzolo, H., Hollway, J. A., Cook, A., DiSilvestro, R. A., Bozzolo, D. R., Crowl, L., Ramadan, Y., & Williams, C. E. (2005) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2005.15.628 · Cited by 130 · see citing works

Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. II. Pervasive developmental disorder-autism.

Mousain-Bosc, M., Roche, M., Polge, A. S., Pradal-Prat, D., Rapin, J. R., & Balì, J.-P. (2006) · PubMed · Cited by 106 · see citing works

Blood Lead Levels in Relation to Menopause, Smoking, and Pregnancy History

Symanski, E., & Hertz‐Picciotto, I. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117369 · Cited by 98 · see citing works

The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test.

Starobrat-Hermelin, B., & Kozielec, T. (1997) · PubMed · Cited by 95 · see citing works

Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children

Dufault, R., Schnoll, R., Lukiw, W. J., LeBlanc, B. W., Cornett, C., Patrick, L., Wallinga, D. B., Gilbert, S. G., & Crider, R. A. (2009) · Behavioral and Brain Functions · doi:10.1186/1744-9081-5-44 · Cited by 92 · see citing works

Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD).

Kozielec, T., & Starobrat-Hermelin, B. (1997) · PubMed · Cited by 87 · see citing works

Role of zinc in maternal and child mental health

DiGirolamo, A. M., & Ramírez‐Zea, M. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26692c · Cited by 84 · see citing works

Magnesium VitB6 Intake Reduces Central Nervous System Hyperexcitability in Children

Mousain-Bosc, M., Roche, M., Rapin, J. R., & Balì, J.-P. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719400 · Cited by 75 · see citing works

Randomized trial of the effect of zinc supplementation on the mental health of school-age children in Guatemala

DiGirolamo, A. M., Ramírez‐Zea, M., Wang, M., Flores‐Ayala, R. C., Martorell, R., Neufeld, L. M., Ramakrishnan, U., Sellen, D., Black, M. M., & Stein, A. D. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29686 · Cited by 75 · see citing works

Towards Prenatal Biomonitoring in North Carolina: Assessing Arsenic, Cadmium, Mercury, and Lead Levels in Pregnant Women

Sanders, A. P., Flood, K., Chiang, S., Herring, A. H., Wolf, L. A., & Fry, R. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031354 · Cited by 74 · see citing works

A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States

Dufault, R., Lukiw, W. J., Crider, R. A., Schnoll, R., Wallinga, D. B., & Deth, R. C. (2012) · Clinical Epigenetics · doi:10.1186/1868-7083-4-6 · Cited by 61 · see citing works

Potential effects of zinc on information processing in boys with attention deficit hyperactivity disorder

Yorbık, Ö., Özdağ, F., Olgun, A., Şenol, M. G., Bek, S., & Akman, Ş. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.11.009 · Cited by 56 · see citing works

Impact of the mother's zinc deficiency on the woman's and newborn's health status

Scheplyagina, L. A. (2005) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2005.07.008 · Cited by 56 · see citing works

Exposure of cadmium from infant formulas and weaning foods

Eklund, G., & Oskarsson, A. (1999) · Food Additives & Contaminants · doi:10.1080/026520399283650 · Cited by 48 · see citing works

Maternal and Neonatal Scalp Hair Concentrations of Zinc, Copper, Cadmium, and Lead: Relationship to Some Lifestyle Factors

Razagui, I. B.-A., & Ghribi, I. (2005) · Biological Trace Element Research · doi:10.1385/bter:106:1:001 · Cited by 44 · see citing works

Zinc status in autistic children

Yorbık, Ö., Akay, C., Sayal, A., Cansever, A., Söhmen, T., & Çavdar, A. O. (2004) · The Journal of Trace Elements in Experimental Medicine · doi:10.1002/jtra.20002 · Cited by 39 · see citing works

Concentrations of calcium, copper, iron, magnesium, potassium, sodium and zinc in adult female hair with different body mass indexes in Taiwan

Wang, C.-T., Chang, W.-T., Zeng, W., & Lin, C.-H. (2005) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2005.070 · Cited by 33 · see citing works

Metallomics study using hair mineral analysis and multiple logistic regression analysis: relationship between cancer and minerals

Yasuda, H., Yoshida, K., Segawa, M., Tokuda, R., Tsutsui, T., Yasuda, Y., & Magara, S. (2009) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-009-0092-y · Cited by 30 · see citing works

Mineral Imbalance in Children with Autistic Disorders

Yasuda, H., Yonashiro, T., Yoshida, K., Ishii, T., & Tsutsui, T. (2005) · Biomedical research on trace elements · doi:10.11299/brte.16.285 · Cited by 29 · see citing works

High Toxic Metal Levels in Scalp Hair of Infants and Children

Yasuda, H., Yonashiro, T., Yoshida, K., Shibazaki, T., Ishii, T., & Tsutsui, T. (2005) · Biomedical research on trace elements · doi:10.11299/brte.16.39 · Cited by 28 · see citing works

A preliminary analysis of trace elements in the scalp hair of patients with severe motor disabilities receiving enteral nutrition

Munakata, M., Onuma, A., Kobayashi, Y., Haginoya, K., Yokoyama, H., Fujiwara, I., Yasuda, H., Tsutsui, T., & Iinuma, K. (2006) · Brain and Development · doi:10.1016/j.braindev.2006.02.004 · Cited by 23 · see citing works

Two Age-Related Accumulation Profiles of Toxic Metals

Yasuda, H., Yoshida, K., Yasuda, Y., & Tsutsui, T. (2012) · Current Aging Science · doi:10.2174/1874609811205020105 · Cited by 23 · see citing works

Relationship between Body Mass Index and Minerals in Male Japanese Adults

Yasuda, H., Yonashiro, T., Yoshida, K., Ishii, T., & Tsutsui, T. (2006) · Biomedical research on trace elements · doi:10.11299/brte.17.316 · Cited by 18 · see citing works

Epidemiology: Complex disorder

HUGHES, V. A. (2012) · Nature · doi:10.1038/491s2a · Cited by 15 · see citing works

Elemental Concentrations in Scalp Hair, Nutritional Status and Health‐Related Quality of Life in Hemodialysis Patients

Ochi, A., Ishimura, E., Tsujimoto, Y., Kakiya, R., Tabata, T., Mori, K., Tahara, H., Shoji, T., Yasuda, H., Nishizawà, Y., et al. (2012) · Therapeutic Apheresis and Dialysis · doi:10.1111/j.1744-9987.2011.01043.x · Cited by 13 · see citing works

High Accumulation of Aluminum in Hairs of Infants and Children

Yasuda, H., Yoshida, K., Segawa, M., Tokuda, R., Yasuda, Y., & Tsutsui, T. (2008) · Biomedical research on trace elements · doi:10.11299/brte.19.57 · Cited by 13 · see citing works

Environmental toxicants and autism spectrum disorders: a systematic review

Rossignol, D. A., Genuis, S. J., & Frye, R. E. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.4 · Cited by 458 · see citing works

Oxidative Stress in Autism Spectrum Disorder

Bjørklund, G., Meguid, N. A., El-Bana, M. A., Tinkov, A. A., Saad, K., Dadar, M., Hemimi, M., Skalny, A. V., Hosnedlová, B., Kizek, R., et al. (2020) · Molecular Neurobiology · doi:10.1007/s12035-019-01742-2 · Cited by 323 · see citing works

Biomarkers in Autism

Goldani, A. A. S., Downs, S. R., Widjaja, F., Lawton, B., & Hendren, R. L. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00100 · Cited by 204 · see citing works

Fetal and postnatal metal dysregulation in autism

Arora, M., Reichenberg, A., Willfors, C., Austin, C., Gennings, C., Berggren, S., Lichtenstein, P., Anckarsäter, H., Tammimies, K., & Bölte, S. (2017) · Nature Communications · doi:10.1038/ncomms15493 · Cited by 169 · see citing works

Systematic review and meta-analysis links autism and toxic metals and highlights the impact of country development status: Higher blood and erythrocyte levels for mercury and lead, and higher hair antimony, cadmium, lead, and mercury

Saghazadeh, A., & Rezaei, N. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.07.011 · Cited by 146 · see citing works

Aluminium in brain tissue in autism

Mold, M., Umar, D., King, A., & Exley, C. (2018) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2017.11.012 · Cited by 147 · see citing works

Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder

Bjørklund, G., Skalny, A. V., Rahman, M. M., Dadar, M., yassa, H. A., Aaseth, J., Chirumbolo, S., Геннадиевна, С. М., & Tinkov, A. A. (2018) · Environmental Research · doi:10.1016/j.envres.2018.05.020 · Cited by 123 · see citing works

The Role of Heavy Metal Pollution in Neurobehavioral Disorders: a Focus on Autism

Gorini, F., Muratori, F., & Morales, M. A. (2014) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-014-0028-3 · Cited by 120 · see citing works

Characterization of biometal profiles in neurological disorders

Pfaender, S., & Grabrucker, A. M. (2014) · Metallomics · doi:10.1039/c4mt00008k · Cited by 117 · see citing works

Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism

Ijomone, O. M., Olung, N. F., Akingbade, G. T., Okoh, C. O. A., & Aschner, M. (2020) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2020.126638 · Cited by 110 · see citing works

Status of essential elements in autism spectrum disorder: systematic review and meta-analysis

Saghazadeh, A., Ahangari, N., Hendi, K., Saleh, F., & Rezaei, N. (2017) · Reviews in the Neurosciences · doi:10.1515/revneuro-2017-0015 · Cited by 103 · see citing works

Autism spectrum disorder: Trace elements imbalances and the pathogenesis and severity of autistic symptoms

Baj, J., Flieger, W., Flieger, M., Forma, A., Sitarz, R., Skórzyńska-Dziduszko, K., Grochowski, C., Maciejewski, R., & Karakuła‐Juchnowicz, H. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.07.029 · Cited by 100 · see citing works

Infants and elderlies are susceptible to zinc deficiency

Yasuda, H., & Tsutsui, T. (2016) · Scientific Reports · doi:10.1038/srep21850 · Cited by 95 · see citing works

Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder

Curtin, P., Austin, C., Curtin, A., Gennings, C., Arora, M., (for the Emergent Dynamical Systems Group), Tammimies, K., Willfors, C., Berggren, S., Siper, P., et al. (2018) · Science Advances · doi:10.1126/sciadv.aat1293 · Cited by 90 · see citing works

Assessment of Infantile Mineral Imbalances in Autism Spectrum Disorders (ASDs)

Yasuda, H., & Tsutsui, T. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10116027 · Cited by 90 · see citing works

Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis

Ding, M., Shi, S., Qie, S., Li, J., & Xi, X. (2023) · Frontiers in Pediatrics · doi:10.3389/fped.2023.1169733 · Cited by 85 · see citing works

Involvement of Neuroinflammation during Brain Development in Social Cognitive Deficits in Autism Spectrum Disorder and Schizophrenia

Nakagawa, Y., & Chiba, K. (2016) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.234476 · Cited by 72 · see citing works

Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3

Pfaender, S., Sauer, A. K., Hagmeyer, S., Mangus, K., Linta, L., Liebau, S., Bockmann, J., Huguet, G., Bourgeron, T., Boeckers, T. M., et al. (2017) · Scientific Reports · doi:10.1038/srep45190 · Cited by 68 · see citing works

Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences ofIn UteroExposure to Environmental Pollutants in a Mouse Model

Hill, D. S., Cabrera, R. M., Schultz, D. W., Zhu, H., Lü, W., Finnell, R. H., & Wlodarczyk, B. J. (2015) · Behavioural Neurology · doi:10.1155/2015/426263 · Cited by 66 · see citing works

Analysis of lead, arsenic and calcium content in the hair of children with autism spectrum disorder

Fiłon, J., Jolanta Ustymowicz-Farbiszewska, J., & Krajewska-Kułak, E. (2020) · BMC Public Health · doi:10.1186/s12889-020-08496-w · Cited by 54 · see citing works

Metal Profiles in Autism Spectrum Disorders: A Crosstalk between Toxic and Essential Metals

Błażewicz, A., & Grabrucker, A. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010308 · Cited by 51 · see citing works

Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman

Hodgson, N., Waly, M. I., Al-Farsi, Y. M., Al‐Sharbati, M. M., Al-Farsi, O. A., Ali, A., Ouhtit, A., Zang, T., Zhou, Z. S., & Deth, R. C. (2014) · Experimental Biology and Medicine · doi:10.1177/1535370214527900 · Cited by 47 · see citing works

Association of autism with toxic metals: A systematic review of case-control studies

Amadi, C. N., Orish, C. N., Frazzoli, C., & Orisakwe, O. E. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173313 · Cited by 45 · see citing works

The chemical exposome of type 2 diabetes mellitus: Opportunities and challenges in the omics era

Misra, B. B., & Misra, A. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.12.001 · Cited by 43 · see citing works

Environmental exposure pathway analysis of trace elements and autism risk in Pakistani children population

Nabgha-e-Amen, Eqani, S. A. M. A. S., Khuram, F., Alamdar, A., Tahir, A., Shah, S. T. A., Nasir, A., Javed, S., Bibi, N., Hussain, A., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.136471 · Cited by 43 · see citing works

Zinc and vitamin A deficiency in a cohort of children with autism spectrum disorder

Sweetman, D., O'Donnell, S. M., Lalor, A., Grant, T., & Greaney, H. (2019) · Child Care Health and Development · doi:10.1111/cch.12655 · Cited by 40 · see citing works

Environmental risk factors for autism spectrum disorders

Liu, L., Zhang, D. X., Rodzinka-pasko, J. K., & Li, Y. (2016) · Der Nervenarzt · doi:10.1007/s00115-016-0172-3 · Cited by 35 · see citing works

Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses

Baecker, T., Mangus, K., Pfaender, S., Chhabra, R., Boeckers, T. M., & Grabrucker, A. M. (2014) · BioMetals · doi:10.1007/s10534-014-9764-1 · Cited by 32 · see citing works

Prenatal Zinc Deficient Mice as a Model for Autism Spectrum Disorders

Sauer, A. K., Hagmeyer, S., & Grabrucker, A. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116082 · Cited by 33 · see citing works

Prenatal Nutritional Factors and Neurodevelopmental Disorders: A Narrative Review

Cernigliaro, F., Santangelo, A., Nardello, R., Cascio, S. L., D’Agostino, S., Correnti, E., Marchese, F., Pitino, R., Valdese, S., Rizzo, C., et al. (2024) · Life · doi:10.3390/life14091084 · Cited by 30 · see citing works

Elemental metabolomics

Zhang, P., Georgiou, C. A., & Brusić, V. (2016) · Briefings in Bioinformatics · doi:10.1093/bib/bbw131 · Cited by 30 · see citing works

Disruption of essential metal homeostasis in the brain by cadmium and high-fat diet

Mazzocco, J. C., Jagadapillai, R., Gozal, E., Kong, M., Xu, Q., Barnes, G. N., & Freedman, J. H. (2020) · Toxicology Reports · doi:10.1016/j.toxrep.2020.08.005 · Cited by 28 · see citing works

Trace Elements in Human Health

Mozrzymas, R. (2018) · doi:10.1002/9781119133780.ch18 · Cited by 27 · see citing works

Oxidative stress indices in ASD children in Sub-Sahara Africa

Omotosho, I. O., Akinade, A. O., Lagunju, I. A., & Yakubu, M. A. (2021) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-021-09379-w · Cited by 25 · see citing works

Zinc Status and Autism Spectrum Disorder in Children and Adolescents: A Systematic Review

do Nascimento, P. K. D. S. B., Silva, D. F. O., de Morais, T. L. S. A., & de Rezende, A. A. (2023) · Nutrients · doi:10.3390/nu15163663 · Cited by 24 · see citing works

The GLO1 C332 (Ala111) allele confers autism vulnerability: Family-based genetic association and functional correlates

Gabriele, S., Lombardi, F., Sacco, R., Napolioni, V., Altieri, L., Tirindelli, M. C., Gregorj, C., Bravaccio, C., Rousseau, F., & Persico, A. M. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.07.021 · Cited by 25 · see citing works

Research into the Association of Cadmium and Manganese Excretion with Thyroid Function and Behavioral Areas in Adolescents with Autism Spectrum Disorders

Błażewicz, A., Grywalska, E., Macek, P., Mertowska, P., Mertowski, S., Wojnicka, J., Durante, N., & Makarewicz, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030579 · Cited by 22 · see citing works

Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population

Ma, J., Wu, J., Li, H., Wang, J., Han, J., & Zhang, R. (2021) · Biological Trace Element Research · doi:10.1007/s12011-021-02690-6 · Cited by 19 · see citing works

Socioeconomic and demographic risk factors of autism spectrum disorder among children and adolescents in Bangladesh: Evidence from a cross-sectional study in 2022

Faruk, M. O., Rahman, M. S., Rana, M. S., Mahmud, S., Neyma, M. A., Karim, M. S., & Alam, N. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289220 · Cited by 19 · see citing works

Optimal dose of zinc supplementation for preventing aluminum-induced neurotoxicity in rats.

Lu, H., Hu, J., Li, J., Pang, W., Hu, Y.-D., Yang, H., Li, W., Huang, C., Zhang, M., & Jiang, Y. (2013) · PubMed Central · doi:10.3969/j.issn.1673-5374.2013.29.007 · Cited by 18 · see citing works

Metallomics Analysis for Assessment of Toxic Metal Burdens in Infants/Children and Their Mothers: Early Assessment and Intervention Are Essential

Yasuda, H., Tsutsui, T., & Suzuki, K. (2020) · Biomolecules · doi:10.3390/biom11010006 · Cited by 18 · see citing works

The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders

Stanton, J. E., Malijauskaite, S., McGourty, K., & Grabrucker, A. M. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.695873 · Cited by 16 · see citing works

Chinese children with autism: A multiple chemical elements profile in erythrocytes

Wu, J., Liu, D., Shou, X., Zhang, J., Meng, F., Liu, Y., Han, S., Zhang, R., Jia, J., Wang, J., et al. (2018) · Autism Research · doi:10.1002/aur.1949 · Cited by 17 · see citing works

Cadmium‐induced global DNA hypermethylation promoting mitochondrial dynamics dysregulation in hippocampal neurons

Geng, H., An, Q., Song, J., He, D., Han, H., & Wang, L. (2023) · Environmental Toxicology · doi:10.1002/tox.24083 · Cited by 15 · see citing works

Arsenic contamination in rice and drinking water: An insight on human cognitive function

Bakar, N. A., Ibrahim, W. N. W., & Faudzi, S. M. M. (2024) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2024.100543 · Cited by 14 · see citing works

Early-life exposure to aluminum and fine motor performance in infants: a longitudinal study

Ma, R., Yang, K., Chen, C., Mao, X., Shen, X., Jiang, L., Ouyang, F., Tian, Y., Zhang, J., He, K., et al. (2021) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-021-00294-9 · Cited by 14 · see citing works

Association between hair lead levels and autism spectrum disorder in children: A systematic review and meta-analysis

Guo, B., Li, H., & Liu, Y. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.05.022 · Cited by 12 · see citing works

Increased iron content in the heart of the Fmr1 knockout mouse

Talvio, K., Kanninen, K. M., White, A. R., Koıstınaho, J., & Castrén, M. L. (2021) · BioMetals · doi:10.1007/s10534-021-00320-1 · Cited by 10 · see citing works

Contribución genética, ambiental y epigenética en la susceptibilidad a los trastornos del espectro autista

Díaz‐Anzaldúa, A., & Martínez, A. D. (2013) · Revista de Neurología · doi:10.33588/rn.5712.2013072 · Cited by 9 · see citing works

Metallomics analysis for early assessment and individualized intervention of neurodevelopmental disorders

Yasuda, H., & Tsutsui, T. (2022) · Metallomics · doi:10.1093/mtomcs/mfac067 · Cited by 7 · see citing works

Urine manganese, cadmium, lead, arsenic, and selenium among autism spectrum disorder children in Kuala Lumpur

Rafi’i, M. R., Jaáfar, M. H., Wahil, M. S. A., & Hanif, S. A. M. (2024) · PeerJ · doi:10.7717/peerj.17660 · Cited by 8 · see citing works

Autism, Chemicals, Probable Cause and Mitigation: A New Examination

Schofield, K. (2016) · Autism - Open Access · doi:10.4172/2165-7890.1000184 · Cited by 7 · see citing works

Analytical methods used in autism spectrum disorders

Kałużna‐Czaplińska, J., Jóźwik-Pruska, J., & Żurawicz, E. (2014) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2014.06.014 · Cited by 7 · see citing works

Deficiency of macro- and micronutrients induced by Lentinula edodes

Grotto, D., Gerenutti, M., Souza, V. C. O., & Barbosa, F. (2015) · Toxicology Reports · doi:10.1016/j.toxrep.2015.02.005 · Cited by 6 · see citing works

The Genetic and Epigenetic Basis Involved in the Pathophysiology of ASD: Therapeutic Implications

Carrascosa-Romero, M. C., & de Cabo, C. (2017) · InTech eBooks · doi:10.5772/66854 · Cited by 5 · see citing works

Zinc in Autism

Grabrucker, S., & Grabrucker, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804562-6.00009-9 · Cited by 3 · see citing works

Micronutrient Research in Autism Spectrum Disorder. A Clinical Study.

Anastasescu, C. M., Stoicănescu, E. C., Badea, O., & Popescu, F. (2023) · PubMed Central · doi:10.12865/chsj.49.03.14 · Cited by 3 · see citing works

Environmental Impact of the Heavy Metal Intoxication on Metabolic, Physiological and Nutritional Profiles in Children with Autism Spectrum Disorder in Morocco

Chouari, R., Leftat, L., Arabi, F. E., & Bour, A. (2024) · Ecological Engineering & Environmental Technology · doi:10.12912/27197050/188057 · Cited by 3 · see citing works

Study On Serum Magnesium, Calcium And Iron In Autism Spectrum Disorder (ASD) Children

Shahjadi, S., Khan, A. S., Ahmed, M. U., Karim, M., Parvin, S., Siddiqi, U. R., Afroz, S., & Mahruba, S. N. (2020) · Journal of Dhaka Medical College · doi:10.3329/jdmc.v27i2.45834 · Cited by 3 · see citing works

The history of metals in autism spectrum disorders

Grabrucker, A. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821132-8.00003-3 · Cited by 3 · see citing works

Elemental and Isotopic Profiles in Blood and Urine of Jordanian Children with Autism Spectrum Disorder: a Preliminary Comparative Study with Neurotypical Children

Rashaid, A. H. B., Shanayneh, T., Jaradat, R. M., Nusair, S. D., & Bashtawi, M. A. (2026) · Biological Trace Element Research · doi:10.1007/s12011-025-04958-7 · Cited by 2 · see citing works

Mercury-induced excitotoxicity in autism spectrum disorder: disruption of glutamatergic homeostasis and the therapeutic role of the selenium–glutathione axis

El-Ansary, A. K., AL-Ayadhi, L. Y., Dewedar, A., Bhat, R. S., Saad, R., & Bjørklund, G. (2026) · BioMetals · doi:10.1007/s10534-026-00791-0 · Cited by 2 · see citing works

Prenatal and Early Life Environmental Stressors: Chemical Moieties Responsible for the Development of Autism Spectrum Disorder

Luhach, K., Sharma, P., Sharma, N., Dhiman, N., Kharkwal, H., & Sharma, B. (2023) · Springer eBooks · doi:10.1007/978-3-031-42383-3_3 · Cited by 3 · see citing works

ESSENTIAL ELEMENTS IN THE ETIOLOGY AND PATHOGENESIS OF AUTISM SPECTRUM DISORDER IN CHILDREN

Chernova, L. N. (2020) · Trace Elements in Medicine (Moscow) · doi:10.19112/2413-6174-2020-21-4-32-39 · Cited by 2 · see citing works

Oxidative Stress and Dietary Interventions in Autism: Exploring the Role of Zinc, Antioxidant Enzymes and Other Micronutrients in the Neurobiology of Autism

Castrén, M. L., Westermarck, T., & Atroshi, F. (2014) · InTech eBooks · doi:10.5772/57512 · Cited by 1 · see citing works

A Review of Potential Metal Toxicity and Mineral Deficiency in Autism

Sikarwar, A., Balakrishnan, H., Tong, S., Vien, K., Yoong, J., Hao, K., Chin, N., Xuan, K., Jiayi, L., & Yee, T. (2015) · International Journal of Biochemistry Research & Review · doi:10.9734/ijbcrr/2015/13913 · Cited by 1 · see citing works

The Situation of Zinc Deficiency: Early Assessment and Intervention Are Essential

Yasuda, H. (2017) · Biomedical research on trace elements · doi:10.11299/brte.27.125 · Cited by 1 · see citing works

Linking trace metal abnormalities to autism—insights from epidemiological studies

Grabrucker, A. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821132-8.00007-0 · Cited by 1 · see citing works

The Effect of Moringa Oleifera Leaves Powder to Level of Serum Superoxide Dismutase (SOD), Lead (Pb), Zink (Zn) and Memory Function of Rat (Rattus norvegicus) Wistar Strain Model of Autism that is Exposed by Pb

Ventiyaningsih, A. D. I., Sujuti, H., Nurtika, W., Rachmawati, S. N., Nurshalilah, N., & Jannah, R. R. (2020) · Research Journal of Life Science · doi:10.21776/ub.rjls.2020.007.01.6 · Cited by 1 · see citing works

Introduction to Bioanalytical Mass Spectrometry

Martins, D. N., Vendramini, P. H., Simionato, A. V. C., & Sussulini, A. (2021) · Springer eBooks · doi:10.1007/978-3-030-82381-8_23 · Cited by 1 · see citing works

Aluminum Toxicity and its Role in Neurodegenerative Diseases: Review

Si̇pahi̇, H., Palabıyık, Ş. S., BALCI, S., & Şahin, G. (2015) · Turkiye Klinikleri Journal of Neurology · doi:10.5336/neuro.2014-41039 · Cited by 1 · see citing works

Biochemical Imbalances and Micronutrient Intervention in Violent and Aggressive Male Children and Adolescents

Hambly, J. L. (2017) · Griffith Research Online · doi:10.25904/1912/2128

Content of magnesium and zinc in hair: systematic review and meta-analysis

Gładysz, I., Kurianiuk, A., & Karczewski, J. (2018) · Medycyna Ogólna i Nauki o Zdrowiu · doi:10.26444/monz/99290

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature ReviewPreprint

Mikulewicz, M., & Chojnacka, K. (2021) · Research Square · doi:10.21203/rs.3.rs-163074/v1

Are there sex differences in interactive associations of environmental exposure to Lead (Pb), Mercury (Hg), and Manganese (Mn) with GST Genes (GSTP1, GSTT1, and GSTM1) in relation to ASD in Jamaican children?

Zwiya, H. T., Samms‐Vaughan, M. E., Bressler, J., Lee, M., Byrd-Williams, C. E., Hessabi, M., Grove, M. L., Shakespeare‐Pellington, S., Loveland, K. A., & Rahbar, M. H. (2023) · Research in Autism · doi:10.1016/j.rasd.2023.102162 · Cited by 1 · see citing works

Perinatal Exposure to Trace Elements: The Dubious Culprit of Autistic Spectrum Disorder in Children

Mohan, K., Omar, B. J., Chacham, S., & Bharti, A. (2023) · Current Pediatric Reviews · doi:10.2174/0115733963251295231031102941

Total cholesterol and triglycerides status in autistic spectrum disorder children: a case-control study on Bangladeshi children

Amin, R., Shahzadi, S., Ahmed, N. U., Rouf, M. A., & Masood, S. (2024) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20240833

Frequency of Hypocalcemia and Hypomagnesemia in Autistic Spectrum Disordered Children of Bangladesh

Parvin, S., Shahzadi, S., Begum, S., & Mahruba, S. N. (2024) · Journal of Rangpur Medical College · doi:10.3329/jrpmc.v9i1.72721

Associations of serum elements and amino acids with autism spectrum disorderPreprint

Yan, L., Wu, J., Xu, R., Cao, B., Wang, W., Han, J., Li, S., Guo, Y., & Zhang, R. (2025) · Research Square · doi:10.21203/rs.3.rs-6961356/v1

Environmental Risk Factors, Toxic Metals, and Essential Elements in Urine Samples of Algerian Children with Severe Autism Spectrum Disorder and Neurotypical Children

Bachir, M., Ziani, M., Zerrouki, K., Nemar, F., Allem, R., & Meziane, M. A. (2026) · Biological Trace Element Research · doi:10.1007/s12011-026-05128-z

Anorexia Nervosa, Schizophrenia, and Autism Spectrum Disorder: A Review of the Role of Tanycytes in Individual and Social Behavior

Dalvi, P. S., Kelly, O., Grady, L., Carris, N., Sullivan, J., & Liu, H. (2026) · Cureus · doi:10.7759/cureus.112030

Hair iron–manganese balance in a large pediatric autism spectrum disorder cohort: Coordinated variation and an exploratory low-Fe/high-Mn subgroup

Bjørklund, G., & Watts, D. (2026) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2026.127943

Brain Metallomics in Neurodevelopmental Disorders: From Pathophysiology to Therapeutics

Ahmadani, A., Nawaz, R., Subramanya, S. B., D’Adamo, M. C., Attlee, A., & Pessia, M. (2026) · Neuromethods · doi:10.1007/978-1-0716-5468-2_11

Assessment of Infantile Mineral Imbalances in Autism Spectrum Disorders (ASDs)

Yasuda, H., & Tsutsui, T. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10116027 · Cited by 90 · see citing works

www.mdpi.com/journal/ijerph Review Assessment of Infantile Mineral Imbalances in Autism Spectrum Disorders (ASDs)

Yasuda, H., & Tsutsui, T. (2013)

Metallomics analysis for early assessment and individualized intervention of neurodevelopmental disorders

Yasuda, H., & Tsutsui, T. (2022) · Metallomics · doi:10.1093/mtomcs/mfac067 · Cited by 7 · see citing works

Metal and essential element levels in hair and association with autism severity

Fiore, M., Barone, R. M. E., Copat, C., Grasso, A., Cristaldi, A., Rizzo, R., & Ferrante, M. (2019) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2019.126409 · Cited by 97 · see citing works

Early Infantile Autism

Bauman, M. L., Filipek, P. A., & Kemper, T. L. (1997) · International review of neurobiology · doi:10.1016/s0074-7742(08)60360-8 · Cited by 61 · see citing works