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Genetic affinities of the Jewish populations of India

Chaubey, Gyaneshwer, Singh, Manvendra, Rai, Niraj, Kariappa, Mini, Singh, Kamayani, Singh, Ashish, Pratap Singh, Deepankar, Tamang, Rakesh, Selvi Rani, Deepa, Reddy, Alla G., Kumar Singh, Vijay, Singh, Lalji, Thangaraj, Kumarasamy·2016·Scientific Reports
DOI 10.1038/srep19166PMC PMC4725824
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Abstract

Due to the lack of written records or inscription, the origin and affiliation of Indian Jewish populations with other world populations remain contentious. Previous genetic studies have found evidence for a minor shared ancestry of Indian Jewish with Middle Eastern (Jewish) populations. However, these studies (relied on limited individuals), haven’t explored the detailed temporal and spatial admixture process of Indian Jewish populations with the local Indian populations. Here, using large sample size with combination of high resolution biparental (autosomal) and uniparental markers (Y chromosome and mitochondrial DNA), we reconstructed genetic history of Indian Jewish by investigating the patterns of genetic diversity. Consistent with the previous observations, we detected minor Middle Eastern specific ancestry component among Indian Jewish communities, but virtually negligible in their local neighbouring Indian populations. The temporal test of admixture suggested that the first admixture of migrant Jewish populations from Middle East to South India (Cochin) occurred during fifth century. Overall, we concluded that the Jewish migration and admixture in India left a record in their genomes, which can link them to the ‘Jewish Diaspora’.

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Crossref · 10.1038/srep19166

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6 of 6 references verified0 citation errors · 0 not checkable

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Figures

Figure 1 The settlement of Jewish populations in Indian Subcontinent. Indian Jewish samples collected in present study are highlighted by maroon dots. The map was modified from the Wikipedia (https://en.wikipedia.org/wiki/File:India-locator-map-blank.svg).
Figure 1 The settlement of Jewish populations in Indian Subcontinent. Indian Jewish samples collected in present study are highlighted by maroon dots. The map was modified from the Wikipedia (https://en.wikipedia.org/wiki/File:India-locator-map-blank.svg).CC BY · PubMed Central
Figure 2 (a) Mean pairwise Fst comparison of Indian Jewish with other regional populations obtained from the autosomal SNP data. (b) Principal component analysis (PCA) of the combined autosomal SNP data of individuals from Eurasia.
Figure 2 (a) Mean pairwise Fst comparison of Indian Jewish with other regional populations obtained from the autosomal SNP data. (b) Principal component analysis (PCA) of the combined autosomal SNP data of individuals from Eurasia.CC BY · PubMed Central
Figure 3 Results of the populationwise unsupervised ‘Structure-like’ ADMIXTURE analysis (K = 7) of world population projecting various Jewish populations.
Figure 3 Results of the populationwise unsupervised ‘Structure-like’ ADMIXTURE analysis (K = 7) of world population projecting various Jewish populations.CC BY · PubMed Central
Figure 4 Comparison of the mean sharing of chunklengths of Indian Jewish vs Indian Dravidian neighbours received from Eurasian populations.
Figure 4 Comparison of the mean sharing of chunklengths of Indian Jewish vs Indian Dravidian neighbours received from Eurasian populations.CC BY · PubMed Central
Figure 5 The placement of various Indian Jewish groups in the PC1 vs. PC2 analysis obtained from haplogroup frequencies for mtDNA; (a) and Y chromosome, (b) within other Eurasian populations.
Figure 5 The placement of various Indian Jewish groups in the PC1 vs. PC2 analysis obtained from haplogroup frequencies for mtDNA; (a) and Y chromosome, (b) within other Eurasian populations.CC BY · PubMed Central

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Citations

Cites

Show all 6 references

Research works printed but not linked: 33

  1. Ehrlich, M. A. Encyclopedia of the Jewish Diaspora (ABC-CLIO, 2009). · DOI
  2. Katz, N. Who Are the Jews of India? (Univ of California Press, 2000). · DOI
  3. Behar, D. M. et al. The matrilineal ancestry of Ashkenazi Jewry: portrait of a recent founder event. Am J Hum Genet. 78, 487–497 (2006). · DOI
  4. Sutton, W. K. et al. Toward resolution of the debate regarding purported crypto-Jews in a Spanish-American population: evidence from the Y chromosome. Ann Hum Biol. 33, 100–111 (2006). · DOI
  5. Feder, J., Ovadia, O., Glaser, B. & Mishmar, D. Ashkenazi Jewish mtDNA haplogroup distribution varies among distinct subpopulations: lessons of population substructure in a closed group. Eur J Hum Genet. 15, 498–500 (2007). · DOI
  6. Behar, D. M. et al. The genome-wide structure of the Jewish people. Nature. 466, 238–242 (2010). · DOI
  7. Moorjani, P. et al. The history of african gene flow into southern europeans, levantines and jews. PLoS Genet. 7, e1001373 (2011). · DOI
  8. Campbell, C. L. et al. North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Proc Natl Acad Sci USA. 109, 13865–13870 (2012). · DOI
  9. Metspalu, M. et al. Most of the extant mtDNA boundaries in south and southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans. BMC Genet. 5, 26 (2004). · DOI
  10. Costa, M. D. et al. A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages. Nature communications. 4, 2543 (2013). · DOI
  11. Cohen, T. et al. Genetic studies on Cochin Jews in Israel: 1. Population data, blood groups, isoenzymes and HLA determinants. Am J Med Genet. 6, 61–73 (1980). · DOI
  12. Behar, D. M. et al. Counting the founders: the matrilineal genetic ancestry of the Jewish Diaspora. PLoS ONE. 3, e2062 (2008). · DOI
  13. Rootsi, S. et al. Phylogenetic applications of whole Y-chromosome sequences and the Near Eastern origin of Ashkenazi Levites. Nature communications. 4, 2928 (2013). · DOI
  14. Li, J. Z. et al. Worldwide human relationships inferred from genome-wide patterns of variation. Science. 319, 1100–1104 (2008). · DOI
  15. Yunusbayev, B. et al. The Caucasus as an Asymmetric Semipermeable Barrier to Ancient Human Migrations. Mol Biol Evol. 29, 359–365 (2012). · DOI
  16. International HapMap 3 Consortium et al. Integrating common and rare genetic variation in diverse human populations. Nature. 467, 52–58 (2010). · DOI · Paper page
  17. Chaubey, G. et al. Population Genetic Structure in Indian Austroasiatic speakers: The Role of Landscape Barriers and Sex-specific Admixture. Mol Biol Evol. 28, 1013–1024 (2011). · DOI
  18. Metspalu, M. et al. Shared and unique components of human population structure and genome-wide signals of positive selection in South Asia. Am J Hum Genet. 89, 731–744 (2011). · DOI
  19. Patterson, N. et al. Ancient admixture in human history. Genetics. 192, 1065–1093 (2012). · DOI · Paper page
  20. Loh, P. R. et al. Inferring admixture histories of human populations using linkage disequilibrium. Genetics. 193, 1233–1254 (2013). · DOI · Paper page
  21. Rieder, M. J., Taylor, S. L., Tobe, V. O. & Nickerson, D. A. Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome. Nucleic Acids Res. 26, 967–73 (1998). · DOI
  22. Andrews, R. M. et al. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet. 23, 147 (1999). · DOI · Paper page
  23. Behar, D. M. et al. A “Copernican” reassessment of the human mitochondrial DNA tree from its root. The American Journal of Human Genetics. 90, 675–684 (2012). · DOI
  24. Karafet, T. M. et al. New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. Genome Res. 18, 830–838 (2008). · DOI · Paper page
  25. Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 81, 559–575 (2007). · DOI · Paper page
  26. Patterson, N., Price, A. L. & Reich, D. Population structure and eigenanalysis. PLoS Genet. 2, e190 (2006). · DOI · Paper page
  27. Alexander, D. H., Novembre, J. & Lange, K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res. 19, 1655–1664 (2009). · DOI · Paper page
  28. Cockerham, C. C. & Weir, B. S. Covariances of relatives stemming from a population undergoing mixed self and random mating. Biometrics. 40, 157–164 (1984). · DOI
  29. Browning, S. R. & Browning, B. L. Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am J Hum Genet. 81, 1084–1097 (2007). · DOI
  30. Thangaraj, K. et al. The influence of natural barriers in shaping the genetic structure of Maharashtra populations. PloS one. 5, e15283 (2010). · DOI
  31. Kivisild, T. et al. The genetic heritage of the earliest settlers persists both in Indian tribal and caste populations. Am J Hum Genet. 72, 313–332 (2003). · DOI
  32. Sengupta, S. et al. Polarity and temporality of high-resolution y-chromosome distributions in India identify both indigenous and exogenous expansions and reveal minor genetic influence of Central Asian pastoralists. Am J Hum Genet. 78, 202–221 (2006). · DOI · Paper page
  33. Trivedi, R. et al. Genetic Imprints of Pleistocene Origin of Indian Populations: A Comprehensive Phylogeographic Sketch of Indian Y-Chromosomes. Int J Hum Genet. 8, 97–118 (2008). · DOI

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Metadata

Authors
Chaubey, G., Singh, M., Rai, N., Kariappa, M., Singh, K., Singh, A., Pratap Singh, D., Tamang, R., Selvi Rani, D., Reddy, A. G., Kumar Singh, V., Singh, L., & Thangaraj, K.
Venue
Scientific Reports
Publisher
Springer Science and Business Media LLC
Published
2016-01-13
Volume
6
Issue
1
ISSN
2045-2322
DOI
10.1038/srep19166
PMC
PMC4725824
Cited by
19
References
6
Language
en
Update notices
correction (2016-05-23)
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CoChat. (2026). Citation check: Genetic affinities of the Jewish populations of India. https://app.cochat.ai/papers/10.1038/srep19166
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Chaubey, G., Singh, M., Rai, N., Kariappa, M., Singh, K., Singh, A., Pratap Singh, D., Tamang, R., Selvi Rani, D., Reddy, A. G., Kumar Singh, V., Singh, L., & Thangaraj, K. (2016). Genetic affinities of the Jewish populations of India. Scientific Reports. https://doi.org/10.1038/srep19166