Controlled size manipulation of free gold nanoparticles by laser irradiation and their facile bioconjugation
Abstract
The average size of gold nanoparticles (AuNP), obtained by laser ablation in solution, is reduced to a few nanometers or increased to tens of nanometers using laser treatments with different strategies. The techniques do not require any stabilizing molecules and the AuNP surface is free from strongly linked ligands. This allowed one-step, immediate and very efficient functionalization of AuNP with commonly used proteins like bovine serum albumin (BSA), which can be detected, using small nanoparticles, down to 3 picomoles and with a 1 : 10 concentration ratio of BSA : AuNP.
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Amendola and Meneghetti observed that with ns pulses in the range of 4-30 nm, effective control of Au particle diameters was possible through heating and rapid cooling.
“They observed that with ns pulses in the range of 4–30 nm, effective control of particle diameters was possible through the mechanism of heating and rapid cooling.”
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- Authors
- Amendola, V., & Meneghetti, M.
- Affiliations
- University of Padua (IT)
- Corresponding author
- Meneghetti, Moreno
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2007
- Volume
- 17
- Issue
- 44
- Pages
- 4705
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2009676206
- Cited by
- 150
- References
- 49
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 7 · 2021: 6 · 2020: 7 · 2019: 8 · 2018: 6 · 2017: 14 · 2016: 5 · 2015: 15 · 2014: 11 · 2013: 11 · 2012: 9
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry (publishedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Funders
- Ministero dell'Università e della Ricerca
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Laser-Ablation Synthesis of Nanoparticles
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Physical Sciences › Materials Science › Materials Chemistry › Nanocluster Synthesis and Applications
- Keywords
- gold nanoparticles, laser ablation in liquid, nanoparticle size control, ligand-free nanoparticles, protein functionalization, bovine serum albumin, bioconjugation, nanoparticle detection
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