The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition
Open accessAbstract
A strained aza-dibenzocyclooctyne was prepared via a high-yielding synthetic route. Copper-free, strain-promoted click reaction with azides showed excellent kinetics, and a functionalised aza-cyclooctyne was applied in fast and efficient PEGylation of enzymes.
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Citations
Cites
Effect of pegylation on pharmaceuticals
Harris, J. M., & Chess, R. B. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1033 · Cited by 3,431
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Sletten, E. M., & Bertozzi, C. R. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900942 · Cited by 3,165
Copper-free click chemistry for dynamic in vivo imaging
Baskin, J. M., Prescher, J. A., Laughlin, S. T., Agard, N. J., Chang, P. V., Miller, I. A., Lo, A., Codelli, J. A., & Bertozzi, C. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707090104 · Cited by 1,833
Peptide and protein PEGylation
Veronese, F. M. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00193-9 · Cited by 1,067
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
Laughlin, S. T., Baskin, J. M., Amacher, S. L., & Bertozzi, C. R. (2008) · Science · doi:10.1126/science.1155106 · Cited by 1,026
Ning, X., Guo, J., Wolfert, M. A., & Boons, G. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200705456 · Cited by 924
Click Chemistry beyond Metal‐Catalyzed Cycloaddition
Becer, C. R., Hoogenboom, R., & Schubert, U. S. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900755 · Cited by 866
Chemoselective Ligation and Modification Strategies for Peptides and Proteins
Hackenberger, C. P. R., & Schwarzer, D. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200801313 · Cited by 761
‘Click’ Chemistry in Polymer and Material Science: An Update
Binder, W. H., & Sachsenhofer, R. (2008) · Macromolecular Rapid Communications · doi:10.1002/marc.200800089 · Cited by 756
“Click”‐Chemistry in Polymer and Material Science: the Update
Binder, W. H. (2008) · Macromolecular Rapid Communications · doi:10.1002/marc.200800332 · Cited by 567
Cited by
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones
Jewett, J. C., Sletten, E. M., & Bertozzi, C. R. (2010) · Journal of the American Chemical Society · doi:10.1021/ja100014q · Cited by 697
A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels
DeForest, C. A., & Tirrell, D. A. (2015) · Nature Materials · doi:10.1038/nmat4219 · Cited by 432
Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons
Stephanopoulos, N., Freeman, R., North, H. A., Sur, S., Jeong, S. J., Tantakitti, F., Kessler, J. A., & Stupp, S. I. (2015) · Nano Letters · doi:10.1021/nl504079q · Cited by 138
Metadata
- Authors
- Debets, M. F., van Berkel, S. S., Schoffelen, S., Rutjes, F. P. J. T., van Hest, J. C. M., & van Delft, F. L.
- Venue
- Chem. Commun.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 46
- Issue
- 1
- Pages
- 97-99
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2039730742
- Cited by
- 580
- References
- 30
- FWCI
- 19.16
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition. https://app.cochat.ai/papers/10.1039/b917797c
- The paper
- Debets, M. F., van Berkel, S. S., Schoffelen, S., Rutjes, F. P. J. T., van Hest, J. C. M., & van Delft, F. L. (2010). Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition. Chem. Commun. https://doi.org/10.1039/b917797c
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.