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Cited by 255

The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.

Exploring the cellular accumulation of metal complexes

Open access
Puckett, Cindy A., Ernst, Russell J., Barton, Jacqueline K.·2010·Dalton Trans.

Abstract

Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a growing number of biological applications have been explored. To be effective, these complexes must reach their intended target inside the cell. Here we review the cellular accumulation of metal complexes, including their uptake, localization, and efflux. Metal complexes are taken up inside cells through various mechanisms, including passive diffusion and entry through organic and metal transporters. Emphasis is placed on the methods used to examine cellular accumulation, to identify the mechanism(s) of uptake, and to monitor possible efflux. Conjugation strategies that have been employed to improve the cellular uptake characteristics of metal complexes are also described.

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Crossref · 10.1039/b922209j

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Metadata

Authors
Puckett, C. A., Ernst, R. J., & Barton, J. K.
Venue
Dalton Trans.
Published
2010
Volume
39
Issue
5
Pages
1159-1170
ISSN
  • 1477-9226 (ISSN-L)
  • 1477-9234
OpenAlex
W2134471751
Cited by
255
References
108
FWCI
5.07
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Exploring the cellular accumulation of metal complexes. https://app.cochat.ai/papers/10.1039/b922209j
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Puckett, C. A., Ernst, R. J., & Barton, J. K. (2010). Exploring the cellular accumulation of metal complexes. Dalton Trans. https://doi.org/10.1039/b922209j

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.