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Polyphosphazene polymers for tissue engineering: An analysis of material synthesis, characterization, and applications
Abstract
Tissue engineering often utilizes biodegradable polymers in the form of porous scaffolds for regenerating de novo tissues. There is an ever-increasing need for biodegradable polymers as temporary substrates for facilitating tissue regeneration. Compared to the widely used polyesters, polyorthoesters, poly(α-amino acids), and poly(anhydrides), biodegradable polyphosphazenes form a unique class of polymers that has vast potential for tissue engineering applications. Polyphosphazenes are linear high molecular weight polymers with an inorganic backbone consisting of alternating phosphorous and nitrogen atoms with two organic side groups attached to each phosphorous atom. The synthetic flexibility of polyphosphazenes has enabled the development of a wide range of polymers with a variety of physical, chemical and biological properties. These biodegradable polyphosphazenes undergo hydrolytic degradation yielding non-toxic and neutral pH degradation products due to the buffering capacity of phosphates and ammonia that are produced simultaneously during polyphosphazene degradation. This review focuses on synthesis of biodegradable polyphosphazenes, their degradation characteristics, biocompatibility, and their applications as tissue regeneration and controlled delivery matrices with a particular emphasis on systems based on polyphosphazenes alone, polyphosphazene blends and polyphosphazene composites.
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“Polyphosphazenes with amino acid side chains are biodegradable and can be employed to aid the regeneration of bone tissue in vivo [186 -189].”
From Ring-Opening Polymerization—An Introductory Review (2013) · cites this paper as [187]
Citations
Cites
Hydrogels for Tissue Engineering
Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,295
Biodegradable polymers as biomaterials
Nair, L. S., & Laurencin, C. T. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.017 · Cited by 4,416
Self-citationBiodegradable synthetic polymers for tissue engineering
CSIRO Molecular Science, B. 1., & Gunatillake, P. (2003) · European Cells and Materials · doi:10.22203/ecm.v005a01 · Cited by 1,765
Recent Developments in Ring Opening Polymerization of Lactones for Biomedical Applications
Albertsson, A.-C., & Varma, I. K. (2003) · Biomacromolecules · doi:10.1021/bm034247a · Cited by 1,582
Tissue Engineering: Orthopedic Applications
Laurencin, C. T., Ambrosio, A. M. A., Borden, M. D., & Cooper, J. A. (1999) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.1.1.19 · Cited by 753
Self-citationPolymers as Biomaterials for Tissue Engineering and Controlled Drug Delivery
Nair, L. S., & Laurencin, C. T. (2006) · Springer eBooks · doi:10.1007/b137240 · Cited by 549
Self-citationSix bioabsorbable polymers: In vitro acute toxicity of accumulated degradation products
Taylor, M. S., Daniels, A. U., Andriano, K. P., & Heller, J. (1994) · Journal of Applied Biomaterials · doi:10.1002/jab.770050208 · Cited by 488
Recent advances in phosphazene (phosphonitrilic) chemistry
Allcock, H. R. (1972) · Chemical Reviews · doi:10.1021/cr60278a002 · Cited by 346
Self-citationToxicity, biodegradation and elimination of polyanhydrides
Katti, D. S., Lakshmi, S., Langer, R., & Laurencin, C. T. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00052-2 · Cited by 305
Self-citationTissue engineered microsphere-based matrices for bone repair:
Borden, M. D., Attawia, M., Khan, Y., & Laurencin, C. T. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00137-5 · Cited by 270
Self-citationBiodegradable polyphosphazenes for drug delivery applications
Lakshmi, S., Katti, D. S., & Laurencin, C. T. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(03)00039-5 · Cited by 266
Self-citationBorden, M. D. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00374-5 · Cited by 227
Polyphosphazene/Nano-Hydroxyapatite Composite Microsphere Scaffolds for Bone Tissue Engineering
Nukavarapu, S. P., Kumbar, S. G., Brown, J. L., Krogman, N. R., Weikel, A. L., Hindenlang, M. D., Nair, L. S., Allcock, H. R., & Laurencin, C. T. (2008) · Biomacromolecules · doi:10.1021/bm800031t · Cited by 189
Self-citationSynthesis of Poly[(amino acid alkyl ester)phosphazenes]
Allcock, H. R., Fuller, T. J., Mack, D. P., Matsumura, K., & Smeltz, K. M. (1977) · Macromolecules · doi:10.1021/ma60058a020 · Cited by 179
Self-citationUse of polyphosphazenes for skeletal tissue regeneration
Laurencin, C. T., Norman, M. E., Elgendy, H. M., El‐Amin, S. F., Allcock, H. R., Pucher, S. R., & Ambrosio, A. A. (1993) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820270716 · Cited by 179
Self-citationA Thermosensitive Poly(organophosphazene) Gel
Lee, B. H., Lee, Y. M., Sohn, Y. S., & Song, S. (2002) · Macromolecules · doi:10.1021/ma012093q · Cited by 174
Allcock, H. R. (1985) · Chemical & Engineering News · doi:10.1021/cen-v063n011.p022 · Cited by 174
Self-citationAllcock, H. R., Pucher, S. R., & Scopelianos, A. G. (1994) · Macromolecules · doi:10.1021/ma00083a001 · Cited by 171
Self-citationNair, L. S., Bhattacharyya, S., Bender, J. D., Greish, Y. E., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2004) · Biomacromolecules · doi:10.1021/bm049759j · Cited by 170
Self-citationThe sintered microsphere matrix for bone tissue engineering: In vitro osteoconductivity studies
Borden, M. D., Attawia, M., & Laurencin, C. T. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.10201 · Cited by 156
Self-citationPoly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization
Andrianov, A. K., DeCollibus, D. P., Gillis, H. A., Kha, H. H., Marin, A., Prausnitz, M. R., Babiuk, L. A., Townsend, H. G. G., & Mutwiri, G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908842106 · Cited by 154
Crommen, J. H. L., Schacht, E. H., & Mense, E. H. G. (1992) · Biomaterials · doi:10.1016/0142-9612(92)90028-m · Cited by 151
Singh, A., Krogman, N. R., Sethuraman, S., Nair, L. S., Sturgeon, J., Brown, P. W., Laurencin, C. T., & Allcock, H. R. (2006) · Biomacromolecules · doi:10.1021/bm050752r · Cited by 150
Self-citationGreish, Y. E., Bender, J. D., Lakshmi, S., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.02.016 · Cited by 150
Self-citationKumbar, S. G., Soppimath, K. S., & Aminabhavi, T. M. (2002) · Journal of Applied Polymer Science · doi:10.1002/app.11552 · Cited by 147
Self-citationPeripheral nerve repair using a poly(organo)phosphazene tubular prosthesis
Langone, F., Lora, S., Veronese, F. M., Caliceti, P., Parnigotto, P. P., Valenti, F., & Palma, G. (1995) · Biomaterials · doi:10.1016/0142-9612(95)93851-4 · Cited by 130
Design of synthetic polymeric structures for cell transplantation and tissue engineering
Cohen, S., Bañó, M. C., Griffith, L. G., Allcock, H. R., Vacanti, J. P., Vacanti, C. A., & Langer, R. (1993) · Clinical Materials · doi:10.1016/0267-6605(93)90082-i · Cited by 130
Self-citationThermosensitive poly(organophosphazene)–paclitaxel conjugate gels for antitumor applications
Chun, C., Lee, S., Kim, S. Y., Yang, H. K., & Song, S. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2008.12.083 · Cited by 128
Chun, C., Lee, S. M., Kim, C. W., Hong, K.-Y., Kim, S. Y., Yang, H. K., & Song, S. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.05.031 · Cited by 123
Controlled release using a new bioerodible polyphosphazene matrix system
Laurencin, C. T., Koh, H. J., Neenan, T. X., Allcock, H. R., & Langer, R. (1987) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820211006 · Cited by 119
Self-citationTissue-engineered bone formation in vivo using a novel sintered polymeric microsphere matrix
Borden, M. D., Attawia, M., Khan, Y., El‐Amin, S. F., & Laurencin, C. T. (2004) · Journal of Bone and Joint Surgery - British Volume · doi:10.1302/0301-620x.86b8.14267 · Cited by 116
Self-citationDegradable polyphosphazene/poly(α-hydroxyester) blends: degradation studies
Ambrosio, A. M. A., Allcock, H. R., Katti, D. S., & Laurencin, C. T. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00293-9 · Cited by 112
Self-citationProtein release from polyphosphazene matrices
Andrianov, A. K. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00122-1 · Cited by 109
Chun, C., Lim, H. J., Hong, K.-Y., Park, K.-H., & Song, S. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.08.011 · Cited by 97
Deng, M., Nair, L. S., Nukavarapu, S. P., Kumbar, S. G., Jiang, T., Krogman, N. R., Singh, A., Allcock, H. R., & Laurencin, C. T. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.09.029 · Cited by 91
Self-citationAllcock, H. R., Cook, W. J., & Mack, D. P. (1972) · Inorganic Chemistry · doi:10.1021/ic50117a003 · Cited by 91
Self-citationPreparation of hydrogel microspheres by coacervation of aqueous polyphosphazene solutions
Andrianov, A. K., Chen, J., & Payne, L. G. (1998) · Biomaterials · doi:10.1016/s0142-9612(97)00227-5 · Cited by 89
Novel polyphosphazene/poly(lactide-co-glycolide) blends: miscibility and degradation studies
Ibim, S. E. M., Ambrosio, A. M. A., Kwon, M. S., El‐Amin, S. F., Allcock, H. R., & Laurencin, C. T. (1997) · Biomaterials · doi:10.1016/s0142-9612(97)80009-9 · Cited by 88
Self-citationBrown, J. L., Nair, L. S., & Laurencin, C. T. (2007) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31033 · Cited by 86
Self-citationAllcock, H. E., Kwon, S., Riding, G. H., Fitzpatrick, R. J., & Bennett, J. L. (1988) · Biomaterials · doi:10.1016/0142-9612(88)90046-4 · Cited by 82
Self-citationDegradable polyphosphazenes for biomedical applications
Crommen, J. H. L., Vandorpe, J., & Schacht, E. H. (1993) · Journal of Controlled Release · doi:10.1016/0168-3659(93)90176-6 · Cited by 82
Synthesis and characterization of pH-sensitive poly(organophosphazene) hydrogels
Allcock, H. (1996) · Biomaterials · doi:10.1016/0142-9612(96)00073-7 · Cited by 80
Self-citationSethuraman, S., Nair, L. S., El‐Amin, S. F., Farrar, R. A., Nguyen, M. N., Singh, A., Allcock, H. R., Greish, Y. E., Brown, P. W., & Laurencin, C. T. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30620 · Cited by 79
Self-citationPolyphosphazene membranes and microspheres in periodontal diseases and implant surgery
Veronese, F. M., Marsilio, F., Lora, S., Caliceti, P., Passi, P., & Orsolini, P. (1999) · Biomaterials · doi:10.1016/s0142-9612(97)00104-x · Cited by 76
Kumbar, S. G., Bhattacharyya, S., Nukavarapu, S. P., Khan, Y., Nair, L. S., & Laurencin, C. T. (2006) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-006-9071-6 · Cited by 76
Self-citationJun, Y. J., Kim, J. I., Jun, M. J., & Sohn, Y. S. (2005) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2005.04.019 · Cited by 74
Water-Soluble Phosphazene Polymers for Parenteral and Mucosal Vaccine Delivery
Payne, L. G., Jenkins, S. A., Andrianov, A. K., & Roberts, B. E. (1995) · Pharmaceutical biotechnology · doi:10.1007/978-1-4615-1823-5_20 · Cited by 69
Biodegradable polymers I. Synthesis of hydrolysis-sensitive poly[(organo)phosphazenes]
Crommen, J. H. L., Schacht, E. H., & Mense, E. H. G. (1992) · Biomaterials · doi:10.1016/0142-9612(92)90102-t · Cited by 66
Allcock, H. R., & Scopelianos, A. G. (1983) · Macromolecules · doi:10.1021/ma00239a001 · Cited by 66
Self-citationAllcock, H. R., & Pucher, S. R. (1991) · Macromolecules · doi:10.1021/ma00001a005 · Cited by 65
Self-citationPolyphosphazene microspheres for insulin delivery
Caliceti, P., Veronese, F. M., & Lora, S. (2000) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(00)00588-3 · Cited by 65
Degradation of Polyaminophosphazenes: Effects of Hydrolytic Environment and Polymer Processing
Andrianov, A. K., & Marin, A. (2006) · Biomacromolecules · doi:10.1021/bm050959k · Cited by 62
Bhattacharyya, S., Kumbar, S. G., Khan, Y., Nair, L. S., Singh, A., Krogman, N. R., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2009) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2009.032 · Cited by 60
Self-citationElectrospun polyphosphazene nanofibers for in vitro rat endothelial cells proliferation
Carampin, P., Conconi, M. T., Lora, S., Menti, A. M., Baiguera, S., Bellini, S., Grandi, C., & Parnigotto, P. P. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30999 · Cited by 58
Miscibility of Bioerodible Polyphosphazene/Poly(lactide-co-glycolide) Blends
Krogman, N. R., Singh, A., Nair, L. S., Laurencin, C. T., & Allcock, H. R. (2007) · Biomacromolecules · doi:10.1021/bm061064q · Cited by 57
Self-citationPhosphazene High Polymers with Steroidal Side Groups
Allcock, H. R., & Fuller, T. J. (1980) · Macromolecules · doi:10.1021/ma60078a003 · Cited by 56
Self-citationPolyphosphates and Other Phosphorus-Containing Polymers for Drug Delivery Applications
Chaubal, M. V., Gupta, A. S., Lopina, S. T., & Bruley, D. F. (2003) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v20.i4.20 · Cited by 54
Controlled macromolecule release from poly(phosphazene) matrices
Ibim, S. E. M., Ambrosio, A. M. A., Larrier, D. R., Allcock, H. R., & Laurencin, C. T. (1996) · Journal of Controlled Release · doi:10.1016/0168-3659(95)00136-0 · Cited by 53
Self-citationGlyceryl polyphosphazenes: synthesis, properties, and hydrolysis
Allcock, H. R., & Kwon, S.-K. (1988) · Macromolecules · doi:10.1021/ma00185a015 · Cited by 53
Self-citationWater-Soluble Biodegradable Polyphosphazenes Containing N -Ethylpyrrolidone Groups
Andrianov, A. K., Marin, A., & Peterson, P. (2005) · Macromolecules · doi:10.1021/ma0509309 · Cited by 53
Tendon Tissue Engineering and Gene Transfer: The Future of Surgical Treatment
Huang, D., Balian, G., & Chhabra, A. B. (2006) · The Journal Of Hand Surgery · doi:10.1016/j.jhsa.2005.10.022 · Cited by 53
Deng, M., Nair, L. S., Nukavarapu, S. P., Kumbar, S. G., Brown, J. L., Krogman, N. R., Weikel, A. L., Allcock, H. R., & Laurencin, C. T. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32334 · Cited by 49
Self-citationMallakpour, S. E., Hajipour, A., & Khoee, S. (2000) · Journal of Applied Polymer Science · doi:10.1002/1097-4628(20000923)77:13 · Cited by 49
Synthesis of a novel biodegradable and electroactive polyphosphazene for biomedical application
Zhang, Q., Yan, Y., Li, S., & Feng, T. (2009) · Biomedical Materials · doi:10.1088/1748-6041/4/3/035008 · Cited by 48
Tyrosine-Bearing Polyphosphazenes
Allcock, H. R., Singh, A., Ambrosio, A. M. A., & Laredo, W. R. (2003) · Biomacromolecules · doi:10.1021/bm030027l · Cited by 46
Self-citationFormation of hydroxyapatite–polyphosphazene polymer composites at physiologic temperature
Greish, Y. E., Bender, J. D., Lakshmi, S., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30145 · Cited by 44
Self-citationIn vitro culture of rat neuromicrovascular endothelial cells on polymeric scaffolds
Conconi, M. T., Lora, S., Baiguera, S., Boscolo, E., Folin, M., Scienza, R., Rebuffat, P., Parnigotto, P. P., & Nussdorfer, G. G. (2004) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30198 · Cited by 43
Patterning Poly(organophosphazenes) for Selective Cell Adhesion Applications
Barrett, E. W., Phelps, M. V. B., Silva, R. J., Gaumond, R. P., & Allcock, H. R. (2005) · Biomacromolecules · doi:10.1021/bm049193z · Cited by 38
Self-citationOsteoblast culture on bioerodible polymers: studies of initial cell adhesion and spread
Laurencin, C. T., Morris, C. D., Pierre-Jacques, H. M., Schwartz, E. R., Keaton, A. R., & Zou, L. (1992) · Polymers for Advanced Technologies · doi:10.1002/pat.1992.220030612 · Cited by 36
Self-citationElectrospinning of Poly[bis(ethyl alanato) phosphazene] Nanofibers
Bhattacharyya, S., Nair, L. S., Singh, A., Krogman, N. R., Greish, Y. E., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2006) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2006.008 · Cited by 36
Self-citationNovel polyphosphazene-hydroxyapatite composites as biomaterials
Laurencin, C. T., Ambrosio, A. M. A., Sahota, J. S., Runge, C. D., Kurtz, S. M., Lakshmi, S., & Allcock, H. R. (2003) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2003.1256268 · Cited by 34
Self-citationNew Acid-Polyfunctional Water-Soluble Phosphazenes: Synthesis and Spectroscopic Characterization
Montoneri, E., Gleria, M., Ricca, G. S., & Pappalardo, G. (1989) · Journal of Macromolecular Science Part A - Chemistry · doi:10.1080/00222338908052000 · Cited by 33
El‐Amin, S. F., Kwon, M. S., Starnes, T., Allcock, H. R., & Laurencin, C. T. (2007) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-006-9096-x · Cited by 33
Self-citationIn Vitro Evaluation of Poly[Bis(Ethyl Alanato)Phosphazene] as a Scaffold for Bone Tissue Engineering
Conconi, M. T., Lora, S., Menti, A. M., Carampin, P., & Parnigotto, P. P. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.811 · Cited by 30
Composite formation from hydroxyapatite with sodium and potassium salts of polyphosphazene
Greish, Y. E., Bender, J. D., Lakshmi, S., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2005) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-005-2531-7 · Cited by 29
Self-citationCui, Y., Zhao, X., Tang, X., & Luo, Y. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00532-5 · Cited by 28
Ibim, S. E. M., El‐Amin, S. F., Goad, M. E. P., Ambrosio, A. M. A., Allcock, H. R., & Laurencin, C. T. (1998) · Pharmaceutical Development and Technology · doi:10.3109/10837459809028479 · Cited by 28
Self-citationAnti-inflammatory Activity of Polyphosphazene-based Naproxen Slow-release Systems
Conforti, A., Bertani, S., Lussignoli, S., Grigolini, L., Terzi, M., Lora, S., Caliceti, P., Marsilio, F., & Veronese, F. M. (1996) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1996.tb05956.x · Cited by 26
Peripheral Nerve Reconstruction with Bioabsorbable Polyphosphazene Conduits
Aldini, N. N., Fini, M., Rocca, M., Martini, L., Giardino, R., Caliceti, P., Veronese, F. M., Lora, S., & Maltarello, M. C. (1997) · Journal of Bioactive and Compatible Polymers · doi:10.1177/088391159701200101 · Cited by 25
Krogman, N. R., Hindenlang, M. D., Nair, L. S., Laurencin, C. T., & Allcock, H. R. (2008) · Macromolecules · doi:10.1021/ma8008417 · Cited by 25
Self-citationGümüşderelı́oğlu, M., & Gür, A. (2002) · Reactive and Functional Polymers · doi:10.1016/s1381-5148(02)00081-0 · Cited by 24
Krogman, N. R., Weikel, A. L., Nguyen, N. Q., Nair, L. S., Laurencin, C. T., & Allcock, H. R. (2008) · Macromolecules · doi:10.1021/ma801961m · Cited by 24
Self-citationPhosphorus containing hydrogels
Ilia, G. (2009) · Polymers for Advanced Technologies · doi:10.1002/pat.1483 · Cited by 21
Lee, S. B., & Song, S. (2005) · Polymer International · doi:10.1002/pi.1702 · Cited by 20
Greish, Y. E., Sturgeon, J., Singh, A., Krogman, N. R., Touny, A. H., Sethuraman, S., Nair, L. S., Laurencin, C. T., Allcock, H. R., & Brown, P. W. (2008) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-008-3427-0 · Cited by 17
Self-citationYuan, W., Song, Q., Zhu, L., Huang, X., Zheng, S., & Tang, X. (2005) · Polymer International · doi:10.1002/pi.1840 · Cited by 12
Nair, L. S., Bender, J. D., Singh, A., Sethuraman, S., Greish, Y. E., Brown, P. W., Allcock, H. R., & Laurencin, C. T. (2004) · MRS Proceedings · doi:10.1557/proc-844-y9.7 · Cited by 11
Self-citation- Self-citation
Flagged first, then by citations
Research works printed but not linked: 6
- Nair, 2006, Adv Biochem Eng Biotechnol, 102, 47
- Welle, 2000, J. Appl. Med. Polym., 4, 6
- Greish, 2005, J. Mater. Sci.: Mater. Med., 16, 613
- Greish, 2008, J. Mater. Sci.: Mater. Med., 19, 3153
- Lakshmi, 2003, Adv. Drug Delivery Rev., 55, 467, 10.1016/S0169-409X(03)00039-5 · DOI
- Oredein-McCoy, 2008, J Microencapsul, 1
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Rothemund, S., & Teasdale, I. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00340k · Cited by 278
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Metadata
- Authors
- Deng, M., Kumbar, S. G., Wan, Y., Toti, U. S., Allcock, H. R., & Laurencin, C. T.
- Affiliations
- University of Connecticut (US)
- Pennsylvania State University (US)
- Corresponding author
- Kumbar, Sangamesh G.
- Laurencin, Cato T.
- Venue
- Soft Matter
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 6
- Issue
- 14
- Pages
- 3119
- ISSN
- 1744-683X (ISSN-L)
- 1744-6848
- OpenAlex
- W2150977308
- Cited by
- 136
- References
- 89
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 4 · 2023: 11 · 2022: 6 · 2021: 7 · 2020: 9 · 2019: 7 · 2018: 7 · 2017: 14 · 2016: 10 · 2015: 12 · 2014: 18 · 2013: 9 · 2012: 10
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Soft Matter (publishedVersion)
- Funders
- National Science Foundation
- National Institutes of Health
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Keywords
- polyphosphazenes, biodegradable polymers, tissue engineering, porous scaffolds, tissue regeneration, hydrolytic degradation, biocompatibility, controlled drug delivery, polymer synthesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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