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Cited by 605

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Anti-inflammatory activity of natural dietary flavonoids

Pan, Min-Hsiung, Lai, Ching-Shu, Ho, Chi-Tang·2010·Food & Function

Abstract

Over the past few decades, inflammation has been recognized as a major risk factor for various human diseases. Acute inflammation is short-term, self-limiting and it's easy for host defenses to return the body to homeostasis. Chronic inflammatory responses are predispose to a pathological progression of chronic illnesses characterized by infiltration of inflammatory cells, excessive production of cytokines, dysregulation of cellular signaling and loss of barrier function. Targeting reduction of chronic inflammation is a beneficial strategy to combat several human diseases. Flavonoids are widely present in the average diet in such foods as fruits and vegetables, and have been demonstrated to exhibit a broad spectrum of biological activities for human health including an anti-inflammatory property. Numerous studies have proposed that flavonoids act through a variety mechanisms to prevent and attenuate inflammatory responses and serve as possible cardioprotective, neuroprotective and chemopreventive agents. In this review, we summarize current knowledge and underlying mechanisms on anti-inflammatory activities of flavonoids and their implicated effects in the development of various chronic inflammatory diseases.

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Metadata

Authors
Pan, M.-H., Lai, C.-S., & Ho, C.-T.
Venue
Food & Function
Published
2010
Volume
1
Issue
1
Pages
15
ISSN
  • 2042-6496 (ISSN-L)
  • 2042-650X
OpenAlex
W2109483752
Cited by
605
References
18
FWCI
11.31
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Anti-inflammatory activity of natural dietary flavonoids. https://app.cochat.ai/papers/10.1039/c0fo00103a
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Pan, M.-H., Lai, C.-S., & Ho, C.-T. (2010). Anti-inflammatory activity of natural dietary flavonoids. Food & Function. https://doi.org/10.1039/c0fo00103a

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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