The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Synthesis, characterization and biocompatibility of “green” synthesized silver nanoparticles using tea polyphenols
Abstract
Since ancient times, people have taken advantage of the antimicrobial effects of colloidal silver particles. Aside from the medical prospects, silver nanoparticles are found in a wide range of commercially available consumer products ranging from cosmetics to household cleansers. Current synthetic methods for creating silver nanoparticles typically call for potentially hazardous chemicals, extreme heat, and produce environmentally dangerous byproducts. Therefore, it is essential that novel "green" synthesis of nanoparticles becomes a reality, and it is imperative to fully analyze the potential toxic effects of these nanoparticles. In this study, we have shown that by reducing silver nitrate in solutions of tea extract or epicatechin of varying concentrations, spherical silver nanoparticles were formed that had controllable size distributions depending on the concentration of tea extract or epicatechin in the samples. Our ultra-resolution microscopy demonstrated that the nanoparticles were in fact interacting with the keratinocytes. Furthermore, evaluation of mitochondrial function (MTS) to assess cell viability and membrane integrity (LDH) in human keratinocytes showed that the silver nanoparticles were nontoxic. These results demonstrated that these nanoparicles are potentially biocompatible and warrant further evaluation in other biological systems.
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Cites
Shape-Controlled Synthesis of Gold and Silver Nanoparticles
Sun, Y., & Xia, Y. (2002) · Science · doi:10.1126/science.1077229 · Cited by 6,506
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Completely “Green” Synthesis and Stabilization of Metal Nanoparticles
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Self-citationSynthesis of Silver Nanostructures with Controlled Shapes and Properties
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Cited by
Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery
Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X. (2021) · Advanced Materials · doi:10.1002/adma.202007356 · Cited by 650
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Self-citationRole of plant phytochemicals and microbial enzymes in biosynthesis of metallic nanoparticles
Ovais, M., Khalil, A. T., Islam, N. U., Ahmad, I., Ayaz, M., Saravanan, M., Shinwari, Z. K., & Mukherjee, S. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9146-7 · Cited by 448
Dauthal, P., & Mukhopadhyay, M. (2016) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.6b00861 · Cited by 445
Metadata
- Authors
- Moulton, M. C., Braydich-Stolle, L. K., Nadagouda, M. N., Kunzelman, S., Hussain, S. M., & Varma, R. S.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 2
- Issue
- 5
- Pages
- 763
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2115808063
- Cited by
- 353
- References
- 34
- FWCI
- 8.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- Moulton, M. C., Braydich-Stolle, L. K., Nadagouda, M. N., Kunzelman, S., Hussain, S. M., & Varma, R. S. (2010). Synthesis, characterization and biocompatibility of “green” synthesized silver nanoparticles using tea polyphenols. Nanoscale. https://doi.org/10.1039/c0nr00046a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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