Cited by 1,156Tea Polyphenols and EffectsPhytochemicals and Antioxidant ActivitiesSkin Protection and Aging

Tea Polyphenols for Health Promotion

Open access
Khan, Naghma, Mukhtar, Hasan·2007·Life Sciences

Abstract

People have been consuming brewed tea from the leaves of the Camellia sinensis plant for almost 50 centuries. Although health benefits have been attributed to tea, especially green tea consumption since the beginning of its history, scientific investigations of this beverage and its constituents have been underway for less than three decades. Currently, tea, in the form of green or black tea, next to water, is the most widely consumed beverage in the world. In vitro and animal studies provide strong evidence that polyphenols derived from tea may possess the bioactivity to affect the pathogenesis of several chronic diseases. Among all tea polyphenols, epigallocatechin-3-gallate has been shown to be responsible for much of the health promoting ability of green tea. Tea and tea preparations have been shown to inhibit tumorigenesis in a variety of animal models of carcinogenesis. However, with increasing interest in the health promoting properties of tea and a significant rise in scientific investigation, this review covers recent findings on the medicinal properties and health benefits of tea with special reference to cancer and cardiovascular diseases.

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Crossref · 10.1016/j.lfs.2007.06.011

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  • The 1H NMR signals in the ethanolic extracts are characteristic of aromatic protons typically found in flavonoids and polyphenolic compounds such as flavones and chalcones.

    “These signals are characteristic of aromatic protons, which are typically found flavonoids and polyphenolic compounds, such as flavones and chalcones [39,40,41].”

    From Comparative Analysis of Infusions and Ethanolic Extracts of Annona muricata Leaves from Colima, Mexico: Phytochemical Profile and Antioxidant Activity (2024) · cites this paper as [41]

    The Introduction describes ring structures in tea catechins and lists flavonols, but it does not interpret ¹H NMR signals from ethanolic extracts. Searches for aromatic-proton signals, flavones, and chalcones found no passage addressing the claimed spectral assignment. The paper’s discussion of polyphenols alone does not verify that assignment. (LLM, conf=0.72)

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  1. Jian L, Xie LP, Lee AH, Binns CW. Protective effect of green tea against prostate cancer: a case-control study in southeast China. International Journal of Cancer. 2004;108(1):130–135. doi: 10.1002/ijc.11550. [DOI] [PubMed] [Google Scholar] · DOI

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Authors
Khan, N., & Mukhtar, H.
Affiliations
University of Wisconsin–Madison (US)
Corresponding author
Mukhtar, Hasan
Venue
Life Sciences
Publisher
Elsevier BV
Published
2007-07
Volume
81
Issue
7
Pages
519-533
ISSN
0024-3205 (ISSN-L)
OpenAlex
W2000519650
Cited by
1,156
References
123
Citations by year
2026: 37 · 2025: 52 · 2024: 60 · 2023: 54 · 2022: 69 · 2021: 61 · 2020: 65 · 2019: 66 · 2018: 66 · 2017: 71 · 2016: 64 · 2015: 56 · 2014: 71 · 2013: 90 · 2012: 81
FWCI
5.01
Type
journal article
Language
en
Open access
Locations
  • Life Sciences (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • U.S. Public Health Service
  • National Cancer Institute (R01CA101039, R01CA 78809, R01CA078809, R01CA120451)
  • National Institute of Diabetes and Digestive and Kidney Diseases (P50DK065303)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Tea Polyphenols and Effects
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
Keywords
tea polyphenols, Camellia sinensis, green tea, black tea, epigallocatechin gallate, health promotion, cancer prevention, cardiovascular disease, tumorigenesis inhibition, chronic disease pathogenesis
MeSH terms
Animals, Anti-Inflammatory Agents, Non-Steroidal, Antioxidants, Biotransformation, Diabetes Mellitus, Epidemiologic Methods, Flavonoids, Health Promotion, Histamine Antagonists, Humans, Longevity, Obesity, Phenols, Tea, Anticarcinogenic Agents, Polyphenols

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