Cited by 338Advanced Polymer Synthesis and CharacterizationBlock Copolymer Self-Assemblybiodegradable polymer synthesis and properties

Cylindrical micelles from the living crystallization-driven self-assembly of poly(lactide)-containing block copolymers

Petzetakis, Nikos, Dove, Andrew P., O'Reilly, Rachel K.·2011·Chem. Sci.

Abstract

The synthesis and self-assembly of poly(lactide)-b-poly(acrylic acid) and poly(lactide)-b-poly(dimethylaminoethylacrylate) block copolymers by a combination of ring-opening polymerization and reverse-addition fragmentation chain transfer (RAFT) polymerization is reported. Self-assembly of block copolymers containing enantiopure homochiral poly(lactide), PLA, by a simple direct dissolution methodology results in core-crystallization to afford micelles with a cylindrical morphology. Amorphous atactic PLA cores and conditions that did not promote crystallization resulted in spherical micelles. Cylindrical micelles were characterized by transmission electron microscopy (TEM) with cryo-TEM, small angle neutron scattering (SANS) and angular dependent dynamic light scattering (DLS) proving that the cylindrical morphology was persistent in solution. Manipulation of the assembly conditions enabled the length and dispersity of the resultant cylindrical micelles to be controlled.

Integrity signals

Registry

Crossref · 10.1039/c0sc00596g

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Petzetakis, N., Dove, A. P., & O'Reilly, R. K.
Affiliations
University of Warwick (GB)
Corresponding author
Dove, Andrew P.
Venue
Chem. Sci.
Published
2011-02-15
Volume
2
Issue
5
Pages
955-960
ISSN
  • 2041-6520 (ISSN-L)
  • 2041-6539
OpenAlex
W1991604237
Cited by
338
References
49
Citations by year
2026: 6 · 2025: 10 · 2024: 11 · 2023: 13 · 2022: 15 · 2021: 25 · 2020: 23 · 2019: 28 · 2018: 34 · 2017: 24 · 2016: 27 · 2015: 25 · 2014: 28 · 2013: 22 · 2012: 32
FWCI
14.58
Type
journal article
Language
en
Open access
closed
Locations
  • Chemical Science (publishedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
  • Science and Technology Facilities Council (submittedVersion)
Funders
  • Advantage West Midlands
  • Research Councils UK
  • Engineering and Physical Sciences Research Council (EP/G004897/1)
  • Science and Technology Facilities Council
  • European Regional Development Fund
Topics
  • Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
  • Physical Sciences › Materials Science › Materials Chemistry › Block Copolymer Self-Assembly
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
Keywords
cylindrical micelles, block copolymers, polylactic acid, crystallization-driven self-assembly, living polymerization, RAFT polymerization, ring-opening polymerization, poly(acrylic acid), core crystallization, polymeric micelles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review