Biological metals and metal-targeting compounds in major neurodegenerative diseases
Barnham, Kevin J., Bush, Ashley I.·2014·Chem. Soc. Rev.
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- Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral SclerosisMahmoud Kiaei, Ashley Ian Bush, Brett M. Morrison, John H. Morrison, Robert A. Cherny, Irene Volitakis, M. Flint Beal, Jon W. Gordon · 2004 · Journal of Neuroscience
- Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease–like symptomsMinglin Lang, Qiangwang Fan, Lei Wang, Yajun Zheng, Guiran Xiao, Xiaoxi Wang, Wei Wang, Yi Zhong, Bing Zhou · 2013 · Neurobiology of Aging
- Interaction of amyloid β peptides with redox active heme cofactor: Relevance to Alzheimer's diseaseDebajyoti Pramanik, Chandradeep Ghosh, Soumya Mukherjee, Somdatta Ghosh Dey · 2012 · Coordination Chemistry Reviews
- Amyloid β and neuromelanin—Toxic or protective molecules?The cellular context makes the differenceK. S. Jagannatha Rao, Muralidhar L. Hegde, S. Anitha, Massimo Musicco, Fabio Andrea Zucca, N. J. TURRO, Luigi Zecca · 2006 · Progress in Neurobiology
- Phosphorylation of Amyloid Precursor Protein at Threonine 668 Is Essential for Its Copper-responsive Trafficking in SH-SY5Y Neuroblastoma CellsKarla M. Acevedo, Carlos Opazo, David Norrish, Leesa M. Challis, Qiao‐Xin Li, Anthony Robert White, Ashley Ian Bush, James Camakaris · 2014 · Journal of Biological Chemistry
- Motor phenotype and magnetic resonance measures of basal ganglia iron levels in Parkinson's diseaseNico Bunzeck, Victoria Singh‐Curry, Cindy Eckart, Nikolaus Weiskopf, Richard J. Perry, Peter G. Bain, Emrah Düzel, Masud Husain B · 2013 · Parkinsonism & Related Disorders
- Pyrrolidine Dithiocarbamate Inhibits Induction of Immunoproteasome and Decreases Survival in a Rat Model of Amyotrophic Lateral SclerosisToni Ahtoniemi, Gundars Goldsteins, Velta Keksa-Goldsteine, Tarja Malm, Katja M. Kanninen, Antero Salminen, Jari Koıstınaho · 2006 · Molecular Pharmacology
- Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulationRamón A. Lorca, Claudio Coddou, María Consuelo Gazitúa, Paulina Bull, Cristián Arredondo, Juan Pablo Huidobro-Toro · 2005 · Journal of Neurochemistry
- ALS-Causing SOD1 Mutations Promote Production of Copper-Deficient Misfolded SpeciesPhilbert Ip, Vikram Khipple Mulligan, Avijit Chakrabartty · 2011 · Journal of Molecular Biology
- NeuroferritinopathyJohn Burn, Patrick Francis Chinnery · 2006 · Seminars in Pediatric Neurology
- Alpha‐synuclein and its role in metal binding: Relevance to Parkinson's diseaseJosephine A. Wright, David R. Brown · 2007 · Journal of Neuroscience Research
- Cognitive decline due to excess synaptic Zn2+ signaling in the hippocampusAtsushi Takeda, Haruna Tamano · 2014 · Frontiers in Aging Neuroscience
- Overexpression of Aβ is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse modelQiao‐Xin Li, Su San Mok, Katrina M. Laughton, Catriona McLean, Irene Volitakis, Robert A. Cherny, Nam Sang Cheung, Anthony Robert White, Colin Louis Masters · 2006 · Aging Cell
- Multi-target, Neuroprotective and Neurorestorative M30 Improves Cognitive Impairment and Reduces Alzheimer's-Like Neuropathology and Age-Related Alterations in MiceLana Kupershmidt, Tamar Amit, Orit Bar‐Am, Orly Weinreb, Moussa B. H. Youdim · 2012 · Molecular Neurobiology
- Zn2+-Aβ40 Complexes Form Metastable Quasi-spherical Oligomers That Are Cytotoxic to Cultured Hippocampal NeuronsInna Solomonov, Eduard Korkotian, Benjamin Born, Yishay Feldman, Arkady Bitler, Farid Rahimi, Huiyuan Li, Gal Bitan, Irit Sagi · 2012 · Journal of Biological Chemistry
- Transcranial ultrasound as a risk marker for Parkinson's diseaseDaniela Berg · 2009 · Movement Disorders
- Substantia nigra hyperechogenicity with LRRK2 G2019S mutationsNorbert Brüggemann, Johann M. Hagenah, Kaili Maloy Stanley, Christine Klein, Cuiling Wang, Deborah Raymond, Laurie J. Ozelius, Susan Bressman, Rachel J. Saunders-Pullman · 2011 · Movement Disorders
- Inhibition of Cu‐Amyloid‐β by using Bifunctional Peptides with β‐Sheet Breaker and Chelator MoietiesMadeleine Jensen, Anne Canning, Sabri Chiha, Pierre Bouquerel, Jeppe T. Pedersen, Jesper Østergaard, Olivier Cuvillier, Isabelle Sasaki, Christelle Hureau, Peter Faller · 2012 · Chemistry - A European Journal
- The Bioinorganic Chemistry of Apoptosis: Potential Inhibitory Zinc Binding Sites in Caspase‐3A. Gerard Daniel, Erica J. Peterson, Nicholas P. Farrell · 2014 · Angewandte Chemie International Edition
- Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-β ProductionEmma H. Gray, Kurt J. De Vos, Colin Dingwall, Michael S. Perkinton, Christopher C.J. Miller · 2010 · Journal of Alzheimer s Disease
- Efficacy and Toxicity of Clioquinol Treatment and A-beta42 Inoculation in the APP/PSI Mouse Model of Alzheimer’s DiseaseYi-Hong Zhang, James B. Raymick, Sumit Sarkar, Debomoy K. Lahiri, Balmiki Ray, David M. Holtzman, Melanie Dumas, Larry C. Schmued · 2013 · Current Alzheimer Research
- CCS knockout mice establish an alternative source of copper for SOD in ALSJoseph S. Beckman, Álvaro G. Estévez, Luis Barbeito, John P. Crow · 2002 · Free Radical Biology and Medicine
- High precision isotope measurements reveal poor control of copper metabolism in ParkinsonismFiona Larner, Barry Sampson, Mark Rehkämper, Dominik Jakob Weiss, Jack R. Dainty, Saidhbhe L. O’Riordan, T. Panetta, P. G. Bain · 2013 · Metallomics
- Is ALS caused by an altered oxidative activity of mutant superoxide dismutase?Ashley Ian Bush · 2002 · Nature Neuroscience
- Imbalance of iron influx and efflux causes brain iron accumulation over time in the healthy adult ratJie‐Hua Chen, Nadia Nur Singh, Huimin Tay, Thomas Walczyk · 2014 · Metallomics
- Formation of carnosine‐Cu(II) complexes prevents and reverts the inhibitory action of copper in P2X4 and P2X7 receptorsClaudio Coddou, Claudio A. Villalobos, Jorge González, Claudio Acuña‐Castillo, Bárbara Loeb L., Juan Pablo Huidobro-Toro · 2002 · Journal of Neurochemistry
- Neuromodulator role of zinc and copper during prolonged ATP applications to P2X4 purinoceptorsClaudio Coddou, Bernardo Morales, Juan Pablo Huidobro-Toro · 2003 · European Journal of Pharmacology
- Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasisB. Elise Needham, Giuseppe D. Ciccotosto, Roberto Cappai · 2014 · Metallomics
- 4-Hydroxynonenal disrupts zinc export in primary rat cortical cellsJ SMITH, Shuling Xiong, Mark A. Lovell · 2005 · NeuroToxicology
- Analogues of oxy-heme Aβ: reactive intermediates relevant to Alzheimer's diseaseManas Seal, Soumya Mukherjee, Debajyoti Pramanik, Kaustuv Mittra, Abhishek Dey, Somdatta Ghosh Dey · 2012 · Chemical Communications
- Monomerized Cu,Zn-superoxide dismutase induces oxidative stress through aberrant Cu bindingHitoshi Kishigami, Seiichi Nagano, Ashley Ian Bush, Saburo Sakoda · 2010 · Free Radical Biology and Medicine
- Effects of copper on A-type potassium currents in acutely dissociated rat hippocampal CA1 neuronsZhi-Dian Niu, Kuai Yu, Yan Gu, Ming Wang, Jiaqi She, Weiheng Chen, Di‐Yun Ruan · 2005 · Neuroreport
- Inhibition of delayed rectifier K+ currents by copper in acutely dissociated rat hippocampal CA1 neuronsZhaorui Niu, J CHEN, Szu‐Han Wang, M WANG, X LI, D RUAN · 2006 · Toxicology Letters
- Errata2009 · The Lancet Neurology
- Diet and Alzheimer's disease: meeting the challenges.Martha Clare Morris · 2006 · PubMed