The DOI matches its Crossref record; 179 of the 180 references it cites were found in a registry or an index.
Sugar-coated: exopolysaccharide producing lactic acid bacteria for food and human health applications
Abstract
The human enteric microbiome represents a veritable organ relied upon by the host for a range of metabolic and homeostatic functions. Through the production of metabolites such as short chain fatty acids (SCFA), folate, vitamins B and K, lactic acid, bacteriocins, peroxides and exopolysaccharides, the bacteria of the gut microbiome provide nutritional components for colonocytes, liver and muscle cells, competitively exclude potential pathogenic organisms and modulate the hosts immune system. Due to the extensive variation in structure, size and composition, microbial exopolysaccharides represent a useful set of versatile natural ingredients for the food industrial sector, both in terms of their rheological properties and in many cases, their associated health benefits. The exopolysaccharide-producing bacteria that fall within the 35 Lactobacillus and five Bifidobacterium species which have achieved qualified presumption of safety (QPS) and generally recognised as safe (GRAS) status are of particular interest, as their inclusion in food products can avoid considerable scrutiny. In addition, additives commonly utilised by the food industry are becoming unattractive to the consumer, due to the demand for a more 'natural' and 'clean labelled' diet. In situ production of exopolysaccharides by food-grade cultures in many cases confers similar rheological and sensory properties in fermented dairy products, as traditional additives, such as hydrocolloids, collagen and alginate. This review will focus on microbial synthesis of exopolysaccharides, the human health benefits of dietary exopolysaccharides and the technofunctional applications of exopolysaccharide-synthesising microbes in the food industry.
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“Moreover, they are involved in bacterial–host interactions and microbial-mediated immunomodulation [6].”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [6]
In the citing paper
“The EPS-producing bacteria, mainly LAB and bifidobacteria, known to be a reservoir of various probiotic strains, have long been used in the food industry thanks to their safety, as they are generally recognized as safe (GRAS) by the Food and Drug Administration (FDA) and are included in the quality presumption of safety (QPS) list of the European Food Safety Authority (EFSA) [6]”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [6]
In the citing paper
“the capacity to endure the harsh condition of the GI tract may vary among different EPS and is strictly dependent on their physicochemical properties [105], being ultimately strain-specific in their gut microbiota modulation ability [6].”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [6]
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Metadata
- Authors
- Ryan, P. M., Ross, R. P., Fitzgerald, G. F., Caplice, N. M., & Stanton, C.
- Affiliations
- Teagasc - The Irish Agriculture and Food Development Authority (IE)
- University College Cork (IE)
- Center for Vascular Biology Research (US)
- Corresponding author
- Stanton, C.
- Venue
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 6
- Issue
- 3
- Pages
- 679-693
- ISSN
- 2042-6496 (ISSN-L)
- 2042-650X
- OpenAlex
- W2116183542
- Cited by
- 221
- References
- 180
- Citations by year
- 2026: 7 · 2025: 18 · 2024: 18 · 2023: 18 · 2022: 30 · 2021: 28 · 2020: 25 · 2019: 19 · 2018: 15 · 2017: 21 · 2016: 12 · 2015: 9
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food & Function (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Science Foundation Ireland (07/CE/B1368)
- European Commission (289517)
- Teagasc
- Enterprise Ireland (CF/2013/3030A/B)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Keywords
- exopolysaccharides, lactic acid bacteria, Lactobacillus, Bifidobacterium, gut microbiota, short-chain fatty acids, fermented dairy products, rheological properties, functional food additives, clean label, human health benefits
- MeSH terms
- Bifidobacterium, Dietary Carbohydrates, Fermentation, Humans, Lactobacillus, Models, Biological, Nutritive Value, Polysaccharides, Bacterial, Surface Properties, Foods, Specialized, Cultured Milk Products, Chemical Phenomena, Lactobacillales, Immunomodulation
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