The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Accelerating peroxidase mimicking nanozymes using DNA
Abstract
DNA-capped iron oxide nanoparticles are nearly 10-fold more active as a peroxidase mimic for TMB oxidation than naked nanoparticles. To understand the mechanism, the effect of DNA length and sequence is systematically studied, and other types of polymers are also compared. This rate enhancement is more obvious with longer DNA and, in particular, poly-cytosine. Among the various polymer coatings tested, DNA offers the highest rate enhancement. A similar acceleration is also observed for nanoceria. On the other hand, when the positively charged TMB substrate is replaced by the negatively charged ABTS, DNA inhibits oxidation. Therefore, the negatively charged phosphate backbone and bases of DNA can increase TMB binding by the iron oxide nanoparticles, thus facilitating the oxidation reaction in the presence of hydrogen peroxide.
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Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Cited by
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Liu, Q., Zhang, A., Wang, R., Zhang, Q., & Cui, D. (2021) · Nano-Micro Letters · doi:10.1007/s40820-021-00674-8 · Cited by 745
Surface modification of nanozymes
Liu, B., & Liu, J. (2017) · Nano Research · doi:10.1007/s12274-017-1426-5 · Cited by 543
Self-citationMulticopper Laccase Mimicking Nanozymes with Nucleotides as Ligands
Liang, H., Lin, F., Zhang, Z., Liu, B., Jiang, S., Yuan, Q., & Liu, J. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b15124 · Cited by 537
Self-citationWang, Z., Dong, K., Liu, Z., Zhang, Y., Chen, Z., Sun, H., Ren, J., & Qu, X. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2016.10.041 · Cited by 401
Rationally Modulate the Oxidase-like Activity of Nanoceria for Self-Regulated Bioassays
Cheng, H., Lin, S., Muhammad, F., Lin, Y.-W., & Wei, H. (2016) · ACS Sensors · doi:10.1021/acssensors.6b00500 · Cited by 334
Metadata
- Authors
- Liu, B., & Liu, J.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 7
- Issue
- 33
- Pages
- 13831-13835
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W1873814962
- Cited by
- 227
- References
- 2
- FWCI
- 6.79
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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