Cited by 151Biosensors and Analytical DetectionOcular Surface and Contact LensElectrowetting and Microfluidic Technologies

Paper-based microfluidic system for tear electrolyte analysis

Open access
Yetisen, Ali K., Jiang, Nan, Tamayol, Ali, Ruiz-Esparza, Guillermo U., Zhang, Yu Shrike, Medina-Pando, Sofía, Gupta, Aditi, Wolffsohn, James S. +3 more·2017·Lab on a Chip

Abstract

This article describes a paper-based microfluidic system that quantifies the concentrations of tear electrolytes using a smartphone-based reader.

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Integrity signals

Registry

Crossref · 10.1039/c6lc01450j

Cites

40 of 40 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Phenylboronic acids form reversible covalent bonds with glucose molecules.

    “Phenylboronic acids form reversible covalent bonds with glucose molecules.70”

    From Wearables in Medicine (2018) · cites this paper as [70]

    The Results and discussion passages describe crown ethers binding metal ions, not phenylboronic acids binding glucose. The Experimental section lists glucose as a material but does not discuss its bonding chemistry. Searches for phenylboronic acid–glucose bonding and reversible boronic acid binding found no passage addressing the claim; page numbers were unavailable in our copy. (LLM, conf=0.75)

    Experimental — accuracy not yet measured

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Percentages, sums and reported differences re-computed from the paper’s own numbers.

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Cites

Flagged first, then by citations

Research works printed but not linked: 32

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Authors
Yetisen, A. K., Jiang, N., Tamayol, A., Ruiz-Esparza, G. U., Zhang, Y. S., Medina-Pando, S., Gupta, A., Wolffsohn, J. S., Butt, H., Khademhosseini, A., & Yun, S.-H.
Affiliations
  • Brigham and Women's Hospital (US)
  • Biomaterials Innovation Research Center
  • Harvard–MIT Division of Health Sciences and Technology (US)
  • Aston University (GB)
  • University of Birmingham (GB)
  • Harvard University (US)
Corresponding author
  • Yetisen, Ali K.
  • Yun, Seok-Hyun
Venue
Lab on a Chip
Published
2017
Volume
17
Issue
6
Pages
1137-1148
ISSN
  • 1473-0189 (ISSN-L)
  • 1473-0197
OpenAlex
W2588545273
Cited by
151
References
40
Citations by year
2026: 11 · 2025: 15 · 2024: 17 · 2023: 8 · 2022: 17 · 2021: 26 · 2020: 21 · 2019: 16 · 2018: 14 · 2017: 5
FWCI
6.90
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Lab on a Chip (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Aston Publications Explorer (Aston University) (acceptedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion, cc-by)
  • Spiral (Imperial College London) (submittedVersion, cc-by)
Funders
  • Wellcome Trust (201929/Z/16/Z)
  • Royal Society
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ocular Surface and Contact Lens
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrowetting and Microfluidic Technologies
Keywords
paper-based microfluidics, dry eye, pH measurement
MeSH terms
Electrolytes, Equipment Design, Humans, Paper, Potassium, Sodium, Tears, Dry Eye Syndromes, Microfluidic Analytical Techniques

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