Tear Based Bioelectronics
Abstract
This work provides an overview of the recent advances in the field of tear‐based wearable electrochemical biodevices, including non‐invasive biosensors, biological fuel cells and biosupercapacitors. Contact lenses are attractive platforms for fabricating non‐invasive self‐contained gadgets for different applications, starting from devices with casual or mundane purposes only, like personalized smart lenses with direct (invisible for others) displays, and ending with biomedical devices for continuous fitness status and/or health care monitoring. Key requirements and challenges that confront researchers in this exciting area are discussed.
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As the concentration of the glucose increases, the phenylboronic acid functionalized hydrogel swells due to Donnan osmotic pressure changes.
“As the concentration of the glucose increases, the phenylboronic acid functionalized hydrogel swells due to Donnan osmotic pressure changes.71”
From Wearables in Medicine (2018) · cites this paper as [71]
Biomarker molecules in tears diffuse directly from the blood and exhibit close tear-blood concentration correlations.
“Not only do biomarker molecules in tears diffuse directly from the blood and exhibit close tear–blood concentration correlations, but also tear analysis presents opportunities for the diagnosis of ocular disease.”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [98]
Tear analysis presents opportunities for the diagnosis of ocular disease.
“Not only do biomarker molecules in tears diffuse directly from the blood and exhibit close tear–blood concentration correlations, but also tear analysis presents opportunities for the diagnosis of ocular disease.”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [98]
Cites
Kim, D.-H., Lu, N., Ma, R., Kim, Y.-S., Kim, R.-H., Wang, S., Wu, J., Won, S. M., Tao, H., Islam, A., et al. (2011) · Science · doi:10.1126/science.1206157 · Cited by 4,836 · see citing works
Non-invasive wearable electrochemical sensors: a review
Bandodkar, A. J., & Wang, J. (2014) · Trends in Biotechnology · doi:10.1016/j.tibtech.2014.04.005 · Cited by 1,247 · see citing works
Wearable salivary uric acid mouthguard biosensor with integrated wireless electronics
Kim, J., Imani, S., de Araujo, W. R., Warchall, J., Valdés-Ramírez, G., Paixão, T. R. L. C., Mercier, P. P., & Wang, J. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.07.039 · Cited by 678 · see citing works
Biofouling: lessons from nature
Bixler, G. D., & Bhushan, B. (2012) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2011.0502 · Cited by 589 · see citing works
A contact lens with embedded sensor for monitoring tear glucose level
Yao, H., Shum, A. J., Cowan, M., Lähdesmäki, I., & Parviz, B. A. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.12.042 · Cited by 513 · see citing works
Berman, E. R. (1991) · Springer eBooks · doi:10.1007/978-1-4757-9441-0 · Cited by 476 · see citing works
Contact Lens Sensors in Ocular Diagnostics
Farandos, N. M., Yetisen, A. K., Monteiro, M. J., Lowe, C. R., & Yun, S. H. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201400504 · Cited by 466 · see citing works
Clinical biochemistry of tears
Haeringen, N. J. V. (1981) · Survey of Ophthalmology · doi:10.1016/0039-6257(81)90145-4 · Cited by 445 · see citing works
Tattoo-based potentiometric ion-selective sensors for epidermal pH monitoring
Bandodkar, A. J., Hung, V. W. S., Jia, W., Valdés-Ramírez, G., Windmiller, J. R., Martinez, A. G., Ramírez, J., Chan, G., Kerman, K., & Wang, J. (2013) · The Analyst · doi:10.1039/c2an36422k · Cited by 379 · see citing works
A 3-$\mu\hbox{W}$ CMOS Glucose Sensor for Wireless Contact-Lens Tear Glucose Monitoring
Liao, Y.-T., Yao, H., Lingley, A., Parviz, B., & Otis, B. P. (2012) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2011.2170633 · Cited by 372 · see citing works
Epidermal Biofuel Cells: Energy Harvesting from Human Perspiration
Jia, W., Valdés‐Ramírez, G., Bandodkar, A. J., Windmiller, J. R., & Wang, J. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201302922 · Cited by 324 · see citing works
Tattoo‐Based Wearable Electrochemical Devices: A Review
Bandodkar, A. J., Jia, W., & Wang, J. (2015) · Electroanalysis · doi:10.1002/elan.201400537 · Cited by 316 · see citing works
Chu, M. X., Miyajima, K., Takahashi, D., Arakawa, T., Sano, K., Sawada, S.-I., Kudo, H., Iwasaki, Y., Akiyoshi, K., Mochizuki, M., et al. (2011) · Talanta · doi:10.1016/j.talanta.2010.10.055 · Cited by 279 · see citing works
Direct electron transfer based enzymatic fuel cells
Falk, M., Blum, Z., & Shleev, S. (2012) · Electrochimica Acta · doi:10.1016/j.electacta.2011.12.133 · Cited by 251 · see citing works
Self-citationWearable temporary tattoo sensor for real-time trace metal monitoring in human sweat
Kim, J., de Araujo, W. R., Samek, I. A., Bandodkar, A. J., Jia, W., Brunetti, B., Paixão, T. R. L. C., & Wang, J. (2015) · Electrochemistry Communications · doi:10.1016/j.elecom.2014.11.024 · Cited by 245 · see citing works
A contact lens with an integrated lactate sensor
Thomas, N., Lähdesmäki, I., & Parviz, B. A. (2012) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2011.12.049 · Cited by 220 · see citing works
Biofuel cell as a power source for electronic contact lenses
Falk, M., Andoralov, V., Blum, Z., Sotres, J., Suyatin, D. B., Ruzgas, T. A., Arnebrant, T., & Shleev, S. (2012) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2012.04.030 · Cited by 211 · see citing works
Self-citationThe role of tear physiology in ocular surface temperature
Craig, J. P., Singh, I., Tomlinson, A., Morgan, P. B., & Efron, N. (2000) · Eye · doi:10.1038/eye.2000.156 · Cited by 193 · see citing works
Cellobiose Dehydrogenase: A Versatile Catalyst for Electrochemical Applications
Ludwig, R., Harreither, W., Tasca, F., & Gorton, L. G. O. (2010) · ChemPhysChem · doi:10.1002/cphc.201000216 · Cited by 191 · see citing works
Murata, K., Kajiya, K., Nakamura, N., & Ohno, H. (2009) · Energy & Environmental Science · doi:10.1039/b912915d · Cited by 188 · see citing works
Investigation of the human tear film proteome using multiple proteomic approaches.
Green‐Church, K. B., Nichols, K. K., Kleinholz, N. M., Zhang, L., & Nichols, J. J. (2008) · PubMed Central · Cited by 184 · see citing works
Wearable textile biofuel cells for powering electronics
Jia, W., Wang, X., Imani, S., Bandodkar, A. J., Ramírez, J., Mercier, P. P., & Wang, J. (2014) · J. Mater. Chem. A · doi:10.1039/c4ta04796f · Cited by 184 · see citing works
Yao, H., Liao, Y., Lingley, A. R., Afanasiev, A., Lähdesmäki, I., Otis, B. P., & Parviz, B. A. (2012) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/22/7/075007 · Cited by 182 · see citing works
Mediatorless sugar/oxygen enzymatic fuel cells based on gold nanoparticle-modified electrodes
Wang, X., Falk, M., Ortiz, R., Matsumura, H., Bobacka, J., Ludwig, R., Bergelin, M., Gorton, L. G. O., & Shleev, S. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2011.10.020 · Cited by 181 · see citing works
Self-citationDemonstration of the mucous layer of the tear film by electron microscopy.
NICHOLS, B. A., Chiappino, M. L., & Dawson, C. R. (1985) · PubMed · Cited by 179 · see citing works
Miniature Biofuel Cell as a Potential Power Source for Glucose-Sensing Contact Lenses
Falk, M., Andoralov, V., Silow, M., Toscano, M. D., & Shleev, S. (2013) · Analytical Chemistry · doi:10.1021/ac4006793 · Cited by 173 · see citing works
Self-citationA Direct Electron Transfer‐Based Glucose/Oxygen Biofuel Cell Operating in Human Serum
Coman, V., Ludwig, R., Harreither, W., Haltrich, D., Gorton, L., Ruzgas, T. A., & Shleev, S. (2009) · Fuel Cells · doi:10.1002/fuce.200900121 · Cited by 167 · see citing works
Self-citationContact lens biofuel cell tested in a synthetic tear solution
Reid, R. C., Minteer, S. D., & Gale, B. K. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.12.034 · Cited by 157 · see citing works
初, 明. (2011) · Medical Entomology and Zoology · Cited by 157 · see citing works
A single-pixel wireless contact lens display
Lingley, A. R., Ali, M., Liao, Y., Mirjalili, R., Klonner, M., Sopanen, M., Suihkonen, S., Shen, T., Otis, B. P., Lipsanen, H., et al. (2011) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/21/12/125014 · Cited by 148 · see citing works
Butovich, I. A. (2011) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.03.003 · Cited by 132 · see citing works
A membrane-, mediator-, cofactor-less glucose/oxygen biofuel cell
Coman, V., Vaz‐Domínguez, C., Ludwig, R., Harreither, W., Haltrich, D., Lacey, A. L. D., Ruzgas, T. A., Gorton, L. G. O., & Shleev, S. (2008) · Physical Chemistry Chemical Physics · doi:10.1039/b808859d · Cited by 125 · see citing works
Self-citationMoulton, S. E., Barisci, J. N., Bath, A., Stella, R., & Wallace, G. G. (2004) · Electrochimica Acta · doi:10.1016/j.electacta.2004.03.034 · Cited by 105 · see citing works
Analysis of tear glucose concentration with electrospray ionization mass spectrometry
Taormina, C. R., Baca, J. T., Asher, S. A., Grabowski, J. J., & Finegold, D. N. (2006) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2006.10.002 · Cited by 99 · see citing works
Self‐Charging Electrochemical Biocapacitor
Pankratov, D., Blum, Z., Suyatin, D. B., Popov, V. O., & Shleev, S. (2013) · ChemElectroChem · doi:10.1002/celc.201300142 · Cited by 98 · see citing works
Self-citationValidation of the Flush Method as an Alternative to Basal or Reflex Tear Collection
Markoulli, M. P., PAPAS, E. B., Petznick, A., & Holden, B. A. (2011) · Current Eye Research · doi:10.3109/02713683.2010.542867 · Cited by 92 · see citing works
Tear fluid content of electrochemically active components including water soluble antioxidants
GOGIA, R., RICHER, S. P., & Rose, R. C. (1998) · Current Eye Research · doi:10.1076/ceyr.17.3.257.5213 · Cited by 89 · see citing works
Biomedical soft contact-lens sensor for in situ ocular biomonitoring of tear contents
Chu, M., Shirai, T., Takahashi, D., Arakawa, T., Kudo, H., Sano, K., Sawada, S.-I., Yano, K., Iwasaki, Y., Akiyoshi, K., et al. (2011) · Biomedical Microdevices · doi:10.1007/s10544-011-9530-x · Cited by 85 · see citing works
Basal, Reflex, and Psycho-emotional Tears
Murube, J. (2009) · The Ocular Surface · doi:10.1016/s1542-0124(12)70296-3 · Cited by 85 · see citing works
Andoralov, V., Falk, M., Suyatin, D. B., Granmo, M., Sotres, J., Ludwig, R., Popov, V. O., Schouenborg, J., Blum, Z., & Shleev, S. (2013) · Scientific Reports · doi:10.1038/srep03270 · Cited by 83 · see citing works
Self-citationFang, A., Ng, H. T., & Li, S. F. Y. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(03)00133-7 · Cited by 76 · see citing works
Haeringen, N. J. V., & Glasius, E. (1977) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/bf00496763 · Cited by 75 · see citing works
A hybrid electric power device for simultaneous generation and storage of electric energy
Pankratov, D., Falkman, P., Blum, Z., & Shleev, S. (2013) · Energy & Environmental Science · doi:10.1039/c3ee43413c · Cited by 72 · see citing works
Self-citationHuman tears: osmotic characteristics.
Benjamin, W. J. “., & Hill, R. M. (1983) · PubMed · Cited by 70 · see citing works
Sack, R. A., Conradi, L., Beaton, A. R., Sathe, S., McNamara, N. A., & Leonardi, A. (2007) · Experimental Eye Research · doi:10.1016/j.exer.2007.07.004 · Cited by 64 · see citing works
Hybrid Electric Power Biodevices
Pankratov, D., Blum, Z., & Shleev, S. (2014) · ChemElectroChem · doi:10.1002/celc.201402158 · Cited by 64 · see citing works
Self-citationAntibody Protein Array Analysis of the Tear Film Cytokines
Li, S., Sack, R. A., Vijmasi, T., Sathe, S., Beaton, A. R., Quigley, D. A., Gallup, M., & McNamara, N. A. (2008) · Optometry and Vision Science · doi:10.1097/opx.0b013e3181824e20 · Cited by 60 · see citing works
Vitamin C Levels in Human Tears
Paterson, C. A., & O'Rourke, M. C. (1987) · Archives of Ophthalmology · doi:10.1001/archopht.1987.01060030096034 · Cited by 56 · see citing works
Miniature Direct Electron Transfer Based Enzymatic Fuel Cell Operating in Human Sweat and Saliva
Falk, M., Pankratov, D., Lindh, L., Arnebrant, T., & Shleev, S. (2014) · Fuel Cells · doi:10.1002/fuce.201400037 · Cited by 48 · see citing works
Self-citationBuffering in human tears: pH responses to acid and base challenge.
Carney, L. G., Mauger, T. F., & Hill, R. M. (1989) · PubMed · Cited by 46 · see citing works
Transparent and flexible, nanostructured and mediatorless glucose/oxygen enzymatic fuel cells
Pankratov, D., Sundberg, R., Sotres, J., Maximov, I. A., Graczyk, M., Suyatin, D. B., González‐Arribas, E., Липкин, А. В., Montelius, L., & Shleev, S. (2015) · Journal of Power Sources · doi:10.1016/j.jpowsour.2015.06.041 · Cited by 40 · see citing works
Self-citationAndoralov, V., Shleev, S., Arnebrant, T., & Ruzgas, T. A. (2013) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-013-6756-x · Cited by 34 · see citing works
Self-citationParviz, B. A. (2009) · IEEE Spectrum · doi:10.1109/mspec.2009.5210042 · Cited by 33 · see citing works
Powering electronic contact lenses: current achievements, challenges, and perspectives
Blum, Z., Pankratov, D., & Shleev, S. (2014) · Expert Review of Ophthalmology · doi:10.1586/17469899.2014.922873 · Cited by 31 · see citing works
Self-citationTear ascorbic acid levels and the total antioxidant status in contact lens wearers: A pilot study
Angayarkanni, N., Saijyothi, A. V., Srinivasan, V., Iyer, G. K., Ramakrishnan, S., Subramanian, M., & Mahadevan, R. (2009) · Indian Journal of Ophthalmology · doi:10.4103/0301-4738.53054 · Cited by 29 · see citing works
A dual microscale glucose sensor on a contact lens, tested in conditions mimicking the eye
Yao, H., Afanasiev, A., Lähdesmäki, I., & Parviz, B. A. (2011) · IEEE International Conference on Micro Electro Mechanical Systems (MEMS) · doi:10.1109/memsys.2011.5734353 · Cited by 29 · see citing works
A Porous ITO Nanoparticles Modified Electrode for the Redox Liquid Immobilization
Niedziółka‐Jönsson, J., Szot, K., Marken, F., & Opałło, M. (2006) · Electroanalysis · doi:10.1002/elan.200603686 · Cited by 24 · see citing works
Transistor‐Like Behavior of a Fungal Laccase
Shleev, S., & Ruzgas, T. A. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200801364 · Cited by 24 · see citing works
Self-citationBiological fuel cells: Divergence of opinion
Shleev, S., Bergel, A., & Gorton, L. G. O. (2015) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2015.07.006 · Cited by 22 · see citing works
Self-citationLiao, W., & Hsu, S. L. (2007) · Nanotechnology · doi:10.1088/0957-4484/18/6/065303 · Cited by 22 · see citing works
Functional modular contact lens
Shum, A. J., Cowan, M., Lähdesmäki, I., Lingley, A. R., Otis, B. P., & Parviz, B. A. (2009) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.827720 · Cited by 18 · see citing works
Patel, J. N., Gray, B. L., Kaminska, B., & Gates, B. D. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500503 · Cited by 18 · see citing works
New Nanobiocomposite Materials for Bioelectronic Devices
Pankratov, D., González‐Arribas, E., Parunova, Y. M., Gorbacheva, M. A., Зейфман, Ю. С., Kuznetsov, S. V., Липкин, А. В., & Shleev, S. (2015) · Acta Naturae · doi:10.32607/20758251-2015-7-1-98-101 · Cited by 8 · see citing works
Self-citationKatz, E. Y. (2006) · Electroanalysis · doi:10.1002/elan.200690023 · Cited by 8 · see citing works
Immunology of the lacrimal gland, tear film and ocular surface
Berry, M. (2005) · British Journal of Ophthalmology · doi:10.1136/bjo.2005.073890 · Cited by 7 · see citing works
Flagged first, then by citations
3 of the 68 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373 · see citing works
Wearable sensors: modalities, challenges, and prospects
Heikenfeld, J., Jajack, A., Rogers, J., Gutruf, P., Tian, L., Pan, T., Li, R., Khine, M., Kim, J., Wang, J., et al. (2018) · Lab on a Chip · doi:10.1039/c7lc00914c · Cited by 1,434 · see citing works
Advanced Carbon for Flexible and Wearable Electronics
Wang, C., Xia, K., Wang, H., Liang, X., Yin, Z., & Zhang, Y. (2018) · Advanced Materials · doi:10.1002/adma.201801072 · Cited by 1,304 · see citing works
Disposable Sensors in Diagnostics, Food, and Environmental Monitoring
Dincer, C., Bruch, R. C., Costa‐Rama, E., Fernández-Abedul, M. T., Merkoçi, A., Manz, A., Urban, G. A., & Güder, F. (2019) · Advanced Materials · doi:10.1002/adma.201806739 · Cited by 972 · see citing works
Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics
Kim, J., Kim, M., Lee, M.-S., Kim, K., Ji, S., Kim, Y.-T., Park, J., Na, K., Bae, K.-H., Kyun Kim, H., et al. (2017) · Nature Communications · doi:10.1038/ncomms14997 · Cited by 951 · see citing works
Wearable Chemical Sensors: Present Challenges and Future Prospects
Bandodkar, A. J., Jeerapan, I., & Wang, J. (2016) · ACS Sensors · doi:10.1021/acssensors.6b00250 · Cited by 778 · see citing works
Yetisen, A. K., Martinez‐Hurtado, J. L., Ünal, B., Khademhosseini, A., & Butt, H. (2018) · Advanced Materials · doi:10.1002/adma.201706910 · Cited by 569 · see citing works
Tackling the Challenges of Enzymatic (Bio)Fuel Cells
Xiao, X., Xia, H.-Q., Wu, R., Bai, L., Yan, L., Magner, E., Cosnier, S., Lojou, É., Zhu, Z., & Liu, A. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00115 · Cited by 507 · see citing works
Advanced Materials for Printed Wearable Electrochemical Devices: A Review
Kim, J., Kumar, R., Bandodkar, A. J., & Wang, J. (2017) · Advanced Electronic Materials · doi:10.1002/aelm.201600260 · Cited by 452 · see citing works
Liu, Y., Wang, H., Zhao, W., Zhang, M., Qin, H., & Xie, Y. (2018) · Sensors · doi:10.3390/s18020645 · Cited by 392 · see citing works
Wearable Biosensors: An Alternative and Practical Approach in Healthcare and Disease Monitoring
Sharma, A., Badea, M., Tiwari, S., & Marty, J. (2021) · Molecules · doi:10.3390/molecules26030748 · Cited by 373 · see citing works
Mishra, R. K., Hubble, L. J., Martín, A., Kumar, R., Barfidokht, A., Kim, J., Musameh, M. M., Kyratzis, I. L., & Wang, J. (2017) · ACS Sensors · doi:10.1021/acssensors.7b00051 · Cited by 345 · see citing works
O2Reduction in Enzymatic Biofuel Cells
Mano, N., & de Poulpiquet, A. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00220 · Cited by 341 · see citing works
Wearable potentiometric ion sensors
Parrilla, M., Cuartero, M., & Crespo, G. A. (2018) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2018.11.024 · Cited by 334 · see citing works
Eyeglasses-based tear biosensing system: Non-invasive detection of alcohol, vitamins and glucose
Sempionatto, J. R., Brazaca, L. C., García-Carmona, L., Bolat, G., Campbell, A. S., Martin, A., Tang, G., Shah, R., Mishra, R. K., Kim, J., et al. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.04.058 · Cited by 315 · see citing works
Eyeglasses based wireless electrolyte and metabolite sensor platform
Sempionatto, J. R., Nakagawa, T., Pavinatto, A., Mensah, S. T., Imani, S., Mercier, P., & Wang, J. (2017) · Lab on a Chip · doi:10.1039/c7lc00192d · Cited by 311 · see citing works
Wireless chemical sensors and biosensors: A review
Kassal, P., Steinberg, M. D., & Steinberg, I. M. (2018) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2018.03.074 · Cited by 308 · see citing works
Reshaping healthcare with wearable biosensors
Smith, A. A., Li, R., & Tse, Z. T. H. (2023) · Scientific Reports · doi:10.1038/s41598-022-26951-z · Cited by 283 · see citing works
Cosnier, S., Gross, A. J., Goff, A. L., & Holzinger, M. (2016) · Journal of Power Sources · doi:10.1016/j.jpowsour.2016.05.133 · Cited by 241 · see citing works
Machine Learning‐Reinforced Noninvasive Biosensors for Healthcare
Zhang, K., Wang, J., Liu, T., Luo, Y., Loh, X. J., & Chen, X. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100734 · Cited by 181 · see citing works
Wearable flexible microfluidic sensing technologies
Chen, S., Zheng, Q., Niu, Y., Yeo, J. C., Liu, Y., Qi, J., Fan, S., Liu, X., Lee, J. Y., & Lim, C. T. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00094-w · Cited by 189 · see citing works
Wen, F., He, T., Liu, H., Chen, H., Zhang, T., & Lee, C. (2020) · Nano Energy · doi:10.1016/j.nanoen.2020.105155 · Cited by 160 · see citing works
Wearable Self‐Powered Electrochemical Devices for Continuous Health Management
Parrilla, M., & Wael, K. D. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202107042 · Cited by 158 · see citing works
Applications of enzymatic biofuel cells in bioelectronic devices – A review
Nasar, A., & Perveen, R. (2019) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2019.04.182 · Cited by 156 · see citing works
Tseng, R. C., Chen, C.-C., Hsu, S., & Chuang, H.-S. (2018) · Sensors · doi:10.3390/s18082651 · Cited by 153 · see citing works
Paper-based microfluidic system for tear electrolyte analysis
Yetisen, A. K., Jiang, N., Tamayol, A., Ruiz-Esparza, G. U., Zhang, Y. S., Medina-Pando, S., Gupta, A., Wolffsohn, J. S., Butt, H., Khademhosseini, A., et al. (2017) · Lab on a Chip · doi:10.1039/c6lc01450j · Cited by 151 · see citing works
Flexible plastic, paper and textile lab-on-a chip platforms for electrochemical biosensing
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Enzyme-based biofuel cells for biosensors and in vivo power supply
Zhang, J. L., Wang, Y. H., Huang, K., Huang, K. J., Jiang, H., & Wang, X. M. (2021) · Nano Energy · doi:10.1016/j.nanoen.2021.105853 · Cited by 132 · see citing works
Point‐of‐Care Smartphone‐based Electrochemical Biosensing
Sun, A. C., & Hall, D. A. (2018) · Electroanalysis · doi:10.1002/elan.201800474 · Cited by 132 · see citing works
Nanoporous Gold-Based Biofuel Cells on Contact Lenses
Xiao, X., Siepenkoetter, T., Conghaile, P. Ó., Leech, D., & Magner, E. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b18708 · Cited by 130 · see citing works
Biofuel cells – Activation of micro- and macro-electronic devices
Gamella, M., Koushanpour, A., & Katz, E. (2017) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2017.09.002 · Cited by 120 · see citing works
Wireless Non‐Invasive Monitoring of Cholesterol Using a Smart Contact Lens
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Artificial intelligence biosensors for continuous glucose monitoring
Jin, X., Cai, A., Xu, T., & Zhang, X. (2023) · Interdisciplinary materials · doi:10.1002/idm2.12069 · Cited by 121 · see citing works
Microfabricated electrochemical sensing devices
Sassa, F., Biswas, G. C., & Suzuki, H. R. (2020) · Lab on a Chip · doi:10.1039/c9lc01112a · Cited by 107 · see citing works
Gross, A. J., Chen, X., Giroud, F., Abreu, C., Goff, A. L., Holzinger, M., & Cosnier, S. (2017) · ACS Catalysis · doi:10.1021/acscatal.7b00738 · Cited by 107 · see citing works
Review—Wearable Biofuel Cells: Past, Present and Future
Bandodkar, A. J. (2016) · Journal of The Electrochemical Society · doi:10.1149/2.0031703jes · Cited by 101 · see citing works
Biosensors and Chemical Sensors for Healthcare Monitoring: A Review
Arakawa, T., Dao, D. V., & Mitsubayashi, K. (2022) · IEEJ Transactions on Electrical and Electronic Engineering · doi:10.1002/tee.23580 · Cited by 100 · see citing works
Printed microfluidic sweat sensing platform for cortisol and glucose detection
Naik, A. R., Zhou, Y., Dey, A. A., Arellano, D. L. G., Okoroanyanwu, U., Secor, E. B., Hersam, M. C., Morse, J. D., Rothstein, J. P., Carter, K. R., et al. (2021) · Lab on a Chip · doi:10.1039/d1lc00633a · Cited by 97 · see citing works
Advanced wearable biosensors for the detection of body fluids and exhaled breath by graphene
Singh, S. U., Chatterjee, S., Lone, S. A., Ho, H.-H., Kaswan, K., Peringeth, K., Khan, A., Chiang, Y., Lee, S., & Lin, Z. (2022) · Microchimica Acta · doi:10.1007/s00604-022-05317-2 · Cited by 100 · see citing works
Kazemi, N., Abdolrazzaghi, M., Light, P. E., & Musı́lek, P. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115668 · Cited by 93 · see citing works
Trovato, V., Sfameni, S., Rando, G., Rosace, G., Libertino, S., Ferri, A., & Plutino, M. R. (2022) · Molecules · doi:10.3390/molecules27175709 · Cited by 91 · see citing works
Xiao, X., Conghaile, P. Ó., Leech, D., Ludwig, R., & Magner, E. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.11.012 · Cited by 86 · see citing works
Agustini, D., Bergamini, M. F., & Junior, L. H. M. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.06.035 · Cited by 81 · see citing works
Edible Electrochemistry: Food Materials Based Electrochemical Sensors
Kim, J., Jeerapan, I., Ciui, B., Hartel, M. C., Martín, A., & Wang, J. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700770 · Cited by 80 · see citing works
Kukkar, D., Zhang, D., Jeon, B., & Kim, K. (2022) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2022.116570 · Cited by 78 · see citing works
Construction of a flexible electrochemiluminescence platform for sweat detection
Chen, M., Cheng, S., Ji, K., Gao, J., Liu, Y., Wen, W., Zhang, X., Wang, S., & Huang, W. (2019) · Chemical Science · doi:10.1039/c9sc01937e · Cited by 77 · see citing works
Inkjet printed flexible non-enzymatic glucose sensor for tear fluid analysis
Romeo, A., Moya, A., Leung, T., Gabriel, G., Villa, R., & Sánchez, S. (2018) · Applied Materials Today · doi:10.1016/j.apmt.2017.12.016 · Cited by 74 · see citing works
The Open Circuit Voltage in Biofuel Cells: Nernstian Shift in Pseudocapacitive Electrodes
Conzuelo, F., Marković, N., Ruff, A., & Schuhmann, W. W. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201808450 · Cited by 74 · see citing works
Wearable self-powered biosensors
Reid, R. C., & Mahbub, I. (2019) · Current Opinion in Electrochemistry · doi:10.1016/j.coelec.2019.10.002 · Cited by 75 · see citing works
Jiang, N., Montelongo, Y., Butt, H., & Yetisen, A. K. (2018) · Small · doi:10.1002/smll.201704363 · Cited by 73 · see citing works
Król-Grzymała, A., Sienkiewicz‐Szłapka, E., Fiedorowicz, E., Rozmus, D., Cieślińska, A., & Grzybowski, A. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710123 · Cited by 67 · see citing works
Xia, H.-Q., Tang, H., Zhou, B., Li, Y., Zhang, X., Shi, Z., Deng, L., Song, R., Li, L., Zhang, Z., et al. (2020) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2020.127962 · Cited by 67 · see citing works
Recent Advances of Prussian Blue-Based Wearable Biosensors for Healthcare
Jiang, Y., Yang, Y., Shen, L., Ma, J., Ma, H., & Zhu, N. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c04420 · Cited by 64 · see citing works
Cheng, S., Gu, Z., Zhou, L., Hao, M., An, H., Song, K., Wu, X., Zhang, K., Zhao, Z., Dong, Y., et al. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.765987 · Cited by 64 · see citing works
Flexible, wearable microfluidic contact lens with capillary networks for tear diagnostics
Yang, X., Yao, H., Zhao, G., Ameer, G. A., Sun, W., Yang, J. H., & Mi, S. (2020) · Journal of Materials Science · doi:10.1007/s10853-020-04688-2 · Cited by 64 · see citing works
Materials, Devices, and Applications for Wearable and Implantable Electronics
Han, W. B., Ko, G., Jang, T., & Hwang, S. (2021) · ACS Applied Electronic Materials · doi:10.1021/acsaelm.0c00724 · Cited by 63 · see citing works
Recent Progress in Implantable Drug Delivery Systems
He, G., Li, H., Liu, J., Hu, Y., Liu, Y., Wang, Z. L., & Jiang, P. (2024) · Advanced Materials · doi:10.1002/adma.202312530 · Cited by 61 · see citing works
Highly Efficient, Flexible Wireless‐Powered Circuit Printed on a Moist, Soft Contact Lens
Takamatsu, T., Chen, Y., Yoshimasu, T., Nishizawa, M., & Miyake, T. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201800671 · Cited by 59 · see citing works
Quo Vadis, Implanted Fuel Cell?
Shleev, S. (2017) · ChemPlusChem · doi:10.1002/cplu.201600536 · Cited by 54 · see citing works
Self-citationMinimally and non-invasive glucose monitoring: the road toward commercialization
Min, S. Q., Geng, H., He, Y., Xu, T., Liu, Q., & Zhang, X. (2025) · Sensors & Diagnostics · doi:10.1039/d4sd00360h · Cited by 55 · see citing works
A Microelectronic Sensor Device Powered by a Small Implantable Biofuel Cell
Bollella, P., Lee, I., Blaauw, D. T., & Katz, E. (2019) · ChemPhysChem · doi:10.1002/cphc.201900700 · Cited by 53 · see citing works
Mengarda, P., Dias, F. A. L., Peixoto, J. V. C., Osiecki, R., Bergamini, M. F., & Junior, L. H. M. (2019) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2019.126663 · Cited by 50 · see citing works
Shitanda, I., Momiyama, M., Watanabe, N., Tanaka, T., Tsujimura, S., Hoshi, Y., & Itagaki, M. (2017) · ChemElectroChem · doi:10.1002/celc.201700561 · Cited by 49 · see citing works
Polymers and Plastics Modified Electrodes for Biosensors: A Review
Lanzalaco, S., & Molina, B. G. (2020) · Molecules · doi:10.3390/molecules25102446 · Cited by 49 · see citing works
Bollella, P., Ludwig, R., & Gorton, L. G. O. (2017) · Applied Materials Today · doi:10.1016/j.apmt.2017.08.009 · Cited by 47 · see citing works
Bobrowski, T., González‐Arribas, E., Ludwig, R., Toscano, M. D., Shleev, S., & Schuhmann, W. W. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.10.016 · Cited by 47 · see citing works
Self-citationPaper-Based Electrochemical Biosensors for Point-of-Care Testing of Neurotransmitters
Li, Y., He, R., Niu, Y., & Li, F. (2019) · Journal of Analysis and Testing · doi:10.1007/s41664-019-00085-0 · Cited by 42 · see citing works
Microfluidic thread based electroanalytical system for green chromatographic separations
Agustini, D., Fedalto, L., Bergamini, M. F., & Junior, L. H. M. (2018) · Lab on a Chip · doi:10.1039/c7lc01267e · Cited by 42 · see citing works
Kumar, T. H. V., Yadav, S. K., & Sundramoorthy, A. K. (2018) · Journal of The Electrochemical Society · doi:10.1149/2.0641816jes · Cited by 42 · see citing works
Electrolyte-Sensing Transistor Decals Enabled by Ultrathin Microbial Nanocellulose
Yuen, J. D., Walper, S. A., Melde, B. J., Daniele, M. A.-A., & Stenger, D. A. (2017) · Scientific Reports · doi:10.1038/srep40867 · Cited by 37 · see citing works
Emerging Nanopixel Light-Emitting Displays: Significance, Challenges, and Prospects
Wu, C., Wang, K., Zhang, Y., Zhou, X., & Guo, T. (2021) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.1c00248 · Cited by 34 · see citing works
Chi, Y. J., Ryu, B., Ahn, S., & Koh, W. (2023) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2023.134601 · Cited by 32 · see citing works
Pankratov, D., Pankratova, G., & Gorton, L. G. O. (2019) · Current Opinion in Electrochemistry · doi:10.1016/j.coelec.2019.09.005 · Cited by 32 · see citing works
Self-citationEnzymatic Glucose-Based Bio-batteries: Bioenergy to Fuel Next-Generation Devices
Buaki-Sogó, M., García‐Carmona, L., Gil‐Agustí, M., Zubizarreta, L., García-Pellicer, M., & Quijano-López, A. (2020) · Topics in Current Chemistry · doi:10.1007/s41061-020-00312-8 · Cited by 32 · see citing works
Ma, R., Shao, R., An, X., Zhang, Q., & Sun, S. (2022) · Journal of Materials Chemistry B · doi:10.1039/d2tb00749e · Cited by 33 · see citing works
González‐Arribas, E., Bobrowski, T., Bari, C. D., Sliozberg, K., Ludwig, R., Toscano, M. D., Lacey, A. L. D., Pita, M., Schuhmann, W. W., & Shleev, S. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.05.040 · Cited by 31 · see citing works
Self-citationTemporary Tattoo pH Sensor with pH‐Responsive Hydrogel via Initiated Chemical Vapor Deposition
Unger, K., Greco, F., & Coclite, A. M. (2021) · Advanced Materials Technologies · doi:10.1002/admt.202100717 · Cited by 31 · see citing works
Pressure-Triggered Microfluidic Contact Lens for Ocular Drug Delivery
Du, Z., Zhao, G., Wang, A., Sun, W., & Mi, S. (2022) · ACS Applied Polymer Materials · doi:10.1021/acsapm.2c01118 · Cited by 31 · see citing works
Electrochemical Sensing in Contact Lenses
Liu, H., Yan, X., Gu, Z., Xiu, G., & Xiao, X. (2021) · Electroanalysis · doi:10.1002/elan.202100342 · Cited by 29 · see citing works
Wearable Microfluidics for Continuous Assay
Lin, P.-H., Nien, H.-H., & Li, B.-R. (2023) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-091322-082930 · Cited by 28 · see citing works
Cellulose nanofiber-based electrode as a component of an enzyme-catalyzed biofuel cell
Tominaga, M., Kuwahara, K., Tsushida, M., & Shida, K. (2020) · RSC Advances · doi:10.1039/d0ra03476b · Cited by 27 · see citing works
Lee, S.-W., Kang, T., Lee, S. K., Lee, K., & Yi, H. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b13070 · Cited by 23 · see citing works
Cellobiose dehydrogenase in biofuel cells
Scheiblbrandner, S., Csarman, F., & Ludwig, R. (2021) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2021.08.013 · Cited by 22 · see citing works
Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
Radwan, A. B., Paramparambath, S., Cabibihan, J., Al-Ali, A. K., Kasák, P., Shakoor, A., Malik, R. A., Mansour, S. A., & Sadasivuni, K. K. (2021) · Biosensors · doi:10.3390/bios11110463 · Cited by 22 · see citing works
Cost-Efficient Printing of Graphene Nanostructures on Smart Contact Lenses
Tang, H., AlQattan, B., Jackson, T. J., Pikramenou, Z., Sun, X. W., Wang, K., & Butt, H. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b21300 · Cited by 21 · see citing works
Wearable biosensors and sample handling strategies
Parlak, O., Curto, V. F., Ojeda, E., Basabe‐Desmonts, L., Benito‐Lopez, F., & Salleo, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102407-2.00004-7 · Cited by 20 · see citing works
Microfluidic contact lenses for ocular diagnostics and drug delivery
Torun, H., Fazla, B., Arman, S., Ozdalgic, B., Yetisen, A. K., & Taşoğlu, S. (2022) · Nano Select · doi:10.1002/nano.202200202 · Cited by 20 · see citing works
Application of Intelligent Medical Sensing Technology
Fu, J., Gao, Q., & Li, S. (2023) · Biosensors · doi:10.3390/bios13080812 · Cited by 19 · see citing works
Towards Detection of Biomarkers in the Eye Using an Aptamer-Based Graphene Affinity Nanobiosensor
Wang, Z., Dai, W., Yu, S., Hao, Z., Pei, R., Moraes, C. G. D., Suh, L. H., Zhao, X., & Lin, Q. (2022) · Talanta · doi:10.1016/j.talanta.2022.123697 · Cited by 18 · see citing works
Abreu, C., Nédellec, Y., Ondel, O., Buret, F., Cosnier, S., Goff, A. L., & Holzinger, M. (2018) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2018.09.033 · Cited by 17 · see citing works
Self-powered sensors for biomarker detection
Li, J., Xu, L., Zou, Y., & Li, Z. (2023) · Sensors & Diagnostics · doi:10.1039/d3sd00050h · Cited by 15 · see citing works
Nanobiohybrid Material‐Based Bioelectronic Devices
Yoon, J., Shin, M., Lim, J., Kim, D. Y., Lee, T., & Choi, J. (2020) · Biotechnology Journal · doi:10.1002/biot.201900347 · Cited by 16 · see citing works
Debnath, S., Debnath, T., & Paul, M. (2025) · Sensors · doi:10.3390/s25216553 · Cited by 14 · see citing works
Advances in Wearable Chemosensors
Korallı, P., & Mouzakis, D. E. (2021) · Chemosensors · doi:10.3390/chemosensors9050099 · Cited by 15 · see citing works
Powering wearable bioelectronic devices
Sekretareva, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102407-2.00005-9 · Cited by 14 · see citing works
Fluid-based wearable sensors: a turning point in personalized healthcare
VURAL, B., Uludağ, İ., İNCE, B., Özyurt, C., ÖZTÜRK, F., & Sezgintürk, M. K. (2023) · TURKISH JOURNAL OF CHEMISTRY · doi:10.55730/1300-0527.3588 · Cited by 13 · see citing works
Park, S. H., & Pak, J. J. (2024) · Sensors · doi:10.3390/s24216945 · Cited by 13 · see citing works
A Smart Dental Floss for Biosensing of Glucose
Sha, P., Luo, X., Shi, W., Liu, Y., & Cui, Y. (2019) · Electroanalysis · doi:10.1002/elan.201800885 · Cited by 12 · see citing works
Guo, Y., Shang, Y., Han, X., Tang, Y., Ma, T., Shen, H., Guo, Y. Y., Wang, X., Wu, D., & Wang, Q. (2025) · Advanced Materials · doi:10.1002/adma.202313837 · Cited by 10 · see citing works
Conzuelo, F., Marković, N., Ruff, A., & Schuhmann, W. W. (2018) · Angewandte Chemie · doi:10.1002/ange.201808450 · Cited by 10 · see citing works
- Authors
- Pankratov, D., González‐Arribas, E., Blum, Z., & Shleev, S.
- Affiliations
- Malmö University (SE)
- Corresponding author
- Shleev, Sergey
- Venue
- Electroanalysis
- Publisher
- Wiley
- Published
- 2016-01-20
- Volume
- 28
- Issue
- 6
- Pages
- 1250-1266
- ISSN
- 1040-0397 (ISSN-L)
- 1521-4109
- OpenAlex
- W2337816605
- Cited by
- 135
- References
- 68
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 7 · 2023: 14 · 2022: 16 · 2021: 14 · 2020: 12 · 2019: 16 · 2018: 18 · 2017: 18 · 2016: 7
- FWCI
- 9.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Electroanalysis (publishedVersion)
- Malmö University Publications (Malmö University) (submittedVersion)
- Funders
- Samsung Electronics Co., Ltd.
- Russian Foundation for Basic Research (13-04-12063, 14-04-32235)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Keywords
- non-invasive biosensors, biofuel cells, contact lenses, smart contact lenses, health monitoring, continuous health monitoring, bioelectrochemical systems
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