Viscoelastic hydrogels for 3D cell culture

Atomic Force Microscope

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Matrix elasticity directs stem cell lineage specification

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Tissue Cells Feel and Respond to the Stiffness of Their Substrate

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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

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Tensional homeostasis and the malignant phenotype

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Force measurements with the atomic force microscope: Technique, interpretation and applications

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Quantification of iPSC-derived vascular networks in novel phototunable angiogenic hydrogelsPreprint

Crosby, C. O., Hillsley, A. V., Kumar, S., Parekh, S. H., Rosales, A. M., & Zoldan, J. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.25.259630 · Cited by 1

OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systemsPreprint

Mendonca, T., Lis-Slimak, K., Matheson, A. B., Smith, M. G., Anane‐Adjei, A. B., Ashworth, J., Cavanagh, R. J., Paterson, L., Dalgarno, P. A., Alexander, C., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.21.489042 · Cited by 1

Tunable bicontinuous macroporous cell culture scaffolds via kinetically controlled phase separationPreprint

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Mechanical Testing of Visocelastic Alginate Hydrogels

Ismail, H. (2022) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/8e42-9h35

THIOL-NORBORNENE HYDROGELS WITH TUNABLE MECHANICAL PROPERTIES FOR ENGINEERED EXTRACELLULAR MATRICES

Nguyen, H. D. (2019) · Figshare · doi:10.25394/pgs.8038535.v1

Engineering a DNA Origami Tool for Multiscale Investigation of Cell Signaling.

Koehler, C. L. (2021) · NCSU Libraries Repository (North Carolina State University Libraries)

Mechanical and Rheological Characterisation of 3D Fibronectin-Collagen Fibrillar Scaffolds

Sadeghi, P. (2021) · uO Research (University of Ottawa) · doi:10.20381/ruor-26000

Novel Implications of Tissue Engineering in the Treatment and Management of Rotator Cuff Tendinopathy

Sanchez, T. C., Diaz, C., George, T., & Eaton, V. L. (2021) · Austin Journal of Biomedical Engineering · doi:10.26420/austinjbiomedeng.2021.1044

Fibre-Reinforced Hydrogels for Functional Cartilage Tissue Engineering

Pahoff, S. (2021) · Queensland University of Technology · doi:10.5204/thesis.eprints.213950

Engineering Human Skin Equivalents to Prevent Infections in Skin Wounds

Vargas, M. I. P. (2021) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.33612/diss.191419793

Ascending and Descending Aortic ECM Hydrogels for Modeling Aortic Wall BiologyPreprint

Lee, Y. C., Richards, T. D., Fantini, D. A., Kaczorowski, D. J., Brown, B. N., & Phillippi, J. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.12.03.518904

Mechanobiology and Applications in Biomaterials for Soft Tissue Repair and Regeneration

Lei, Y. F., Li, J., & Billiar, K. L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822944-6.00065-7

“Optimality of motor and clutch mechanical properties in a generalized model for cell traction forces”Preprint

Alonso‐Matilla, R., Provenzano, P. P., & Odde, D. J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.20.529282

Modular Enzyme-Responsive Polysaccharide-Based Hydrogels for Biofabrication

Naeimipour, S. (2023) · Linköping studies in science and technology. Dissertations · doi:10.3384/9789180750349

Current design and advances of hydrogel for retinal tissue engineering and regenerative medicine

Choi, J. H., Tumursukh, N.-E., Kim, W., Seo, J.-S., Kim, S., Kim, S. E., Song, J. E., & Khang, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-823948-3.00025-7

Cellular Requirements and Preparation for Bioprinting

Dasgupta, S., Sharma, V., & Barui, A. (2024) · Wiley eBooks · doi:10.1002/9781119894407.ch2

Organ-Derived Extracellular Matrix (ECM) Hydrogels: Versatile Systems to Investigate the Impact of Biomechanics and Biochemistry on Cells in Disease Pathology

Harmsen, M. C., Getova, V. E., Zhang, M., Zhao, F., van Dongen, J. A., Martinez-Garcia, F. D., Nizamoglu, M., & Burgess, J. K. (2024) · Springer eBooks · doi:10.1007/978-3-031-56363-8_43

Development of a Robotized Screening Method for Microfibers Based on Viscoelasticity*

Xie, C., Sun, T., Wen, K., Chen, S., & Wang, H. (2024) · International Conference on Advanced Robotics and Mechatronics (ICARM) · doi:10.1109/icarm62033.2024.10715903

Highly Deformable Phototunable Viscoelastic Fluid Interface Modulates Cellular Adaptive Wetting Behavior

Zhou, J., Wang, H., & Nakanishi, J. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202414534

The role of umbilical cord mesenchymal stem cells and bioactive hydrogels in promoting regeneration of degenerated intervertebral discs

Zhou, J., Wang, J., Song, Z., He, Z., Li, Z., Shao, J., Du, Y., Li, J., Zhang, W., Li, C., et al. (2025) · Advanced Orthopaedics · doi:10.1016/j.advop.2025.03.001

Fiber-Based Hydrogels for Designing Viscoelastic Responses in Particle-Based Biomaterials That Support Embedded 3D Printing

Grewal, G. S., Ferrarese, E., Porter, L., Helein, G. T., & Highley, C. B. (2026) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01432 · Cited by 1

Advanced biomaterials for radiation-induced dermatitis: from pathophysiological mechanisms to translational interfaces

Ma, C., Zhu, H., Liu, C., & Wang, W. (2025) · Frontiers in Materials · doi:10.3389/fmats.2025.1631141

Independently Tunable Viscoelasticity in Hydrogels as a Mechanical Cue for Tissue Engineering

Qiao, Q., Sun, Y., Wang, J., Li, X., Zhang, L., Yang, H., Zhang, N., Zhang, K., Zhao, Z., & Bai, Y. (2025) · Tissue Engineering Part B Reviews · doi:10.1177/19373341251377696 · Cited by 1

Arresting Microphase Separation Encodes Material Mechanics by Sculpting Microarchitectures and Local Polymer Enrichment

Johnbosco, C., Dalenoord, F., Hiemstra, J., Yu, N., Wolfel, A., Bosmans, C., Gering, C., Willemen, N. G. A., Shin, S. R., & Leijten, J. (2025) · Advanced Materials · doi:10.1002/adma.202512578

The study of ECM hardness and mechanical pressure promoting TSCC progression by activating RET in a 4D culture system

Wang, Y., Wang, Y., Xing, Y., & Jing, G. (2025) · Materials & Design · doi:10.1016/j.matdes.2025.114590

Micromechanical characterization of alginate hydrogels using confocal Brillouin spectroscopy

Kizilov, M., Cheburkanov, V. D., Jung, S., Morais, M. R. G., Pêgo, A. P., & Yakovlev, V. V. (2026) · doi:10.1117/12.3085329

Mechanical Cues Regulate Estrogen and Progesterone‐Induced Nascent ECM Deposition by Human Endometrial Stromal Fibroblasts

Hinds, G. K., Velieva, A. E., Liu, Y., Roy, A., Chavali, R., & Loebel, C. (2026) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbma.70038

An oxo-mechanical coupling determines cell statePreprint

Sreepadmanabh, M., Hariharan, N., Palakodeti, D., & Bhattacharjee, T. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.12.711491

Bioreactor Design and Engineering for Cultivated Meat Manufacturing

Schlieker, M.-L., Vorländer, D., Pasitka, L., Bode, S., Krampitz, T., Treinen, C., & Henkel, M. (2026) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2026_314

Développement et caractérisation d'hydrogels d'acide hyaluronique auto-réticulants injectables en ingénierie tissulaire du squelette

Flégeau, K. (2019) · theses.fr (ABES) · doi:10.70675/883d99f3z556az4130z9194z5fa38b59e61c

Impact of the viscoelastic properties of the 3D environment on the fate of artificial stem cell spheroids

Lemarié, L. (2024) · theses.fr (ABES) · doi:10.70675/4b717f02z8fbcz4870z85e7z88b55140b5ec

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

González‐Martínez, D. A., Tafoya, A. A., González‐Martínez, E., Carpio, M. B., Andrade, L. D. S., Chow, C., Dabaghi, M., Hirota, J. A., & Moran-Mirabal, J. M. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.71248

Viscoelasticity drives EMT in pancreatic intraepithelial neoplasia

Pascucci, A., Karim, S., Morton, J. P., Vassalli, M., & Walker, M. (2026) · Mechanobiology · doi:10.1177/29780241261450044

An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces

Zhou, Y., Zheng, P., Cheung, B., Huang, C. Y., Ryder, G., Clark, J. R., Maruf, D. S. A. A., Wu, Y.-H., Ker, M., Huang, X., et al. (2026) · Advanced Materials Interfaces · doi:10.1002/admi.70566

iPSC-Derived Chondroprogenitors as a Promising Cell Source for Cartilage Engineering: A Comparison with MSCs in Unmodified and Peptide-Functionalized Alginate HydrogelsPreprint

Vieri, M. L., Thomson, A. R., Dalby, M. J., Kolundžić, N., Ansalone, C., Dietrich, B., Tsimbouri, P. M., Shaw, T., Huesa, C., Adams, D. J., et al. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6934260

Matrix stress relaxation drives glioblastoma cell response in viscoelastic biomaterials

Ghorbani, S., Huang, M. S., Zhang, D. H., Liu, Y., Long, C. M., Zwetsloot, R., Mozipo, E. A. T., Rao, R. R., Enejder, A. M. K., & Heilshorn, S. C. (2026) · Science Advances · doi:10.1126/sciadv.aef7087

Laser Speckle Rheological Microscopy (SHEAR) Mapping of Poly(ethylene glycol) diacrylate (PEGDA) Gels

Moquin, K., Wu, J., & Hajjarian, Z. (2026) · Optics in the Life Sciences · doi:10.1364/translational.2026.jm4a.41

Toward an Integrated Strategy for Volumetric Muscle Loss Regeneration

Dcosta, C., Zhang, K. L., Duazo, M., Grubišić, V., Hamzah, R. N., & Alghazali, K. M. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15155901

Encapsulation and Controlled Release of Human Spinal Cord Organoid‐Derived Extracellular Vesicles for Tissue Patterning in Viscoelastic Hyaluronic Acid Hydrogels

Chen, X., Liu, C., McDaniel, G., Joshi, S., Ma, S., Sen, J. B., Driscoll, T. P., Zeng, C., & Li, Y. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.71472

Cell-Type-Tailored Hydrogels for Adoptive Cell Therapy in Cancer

Shin, J. H., Song, Y., & Park, J. (2026) · Gels · doi:10.3390/gels12080678

Fabrication of a visible light photocrosslinkable κ-carrageenan-gelatin hydrogel patch to aid in wound healing applications

Menaga, S., & Kumari, S. (2026) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2026.1846548

Biomechanics-guided engineering of in vitro cardiac tissues for mechanical function reconstruction

Xia, T., Zhang, D., Zheng, Y., Fan, Y., & Liu, X. (2026) · Biomaterials Advances · doi:10.1016/j.bioadv.2026.215106

A photo-crosslinkable hyaluronic acid–collagen hydrogel maintains epithelial integrity and supports intestinal organoid stemness

Cho, Y., Park, S. Y., Han, D., Lee, H. J., & Lee, J. H. (2026) · Regenerative Biomaterials · doi:10.1093/rb/rbag171

From drop impact to cellular response: Transient interfacial force fields, contact-line physics, and mechanotransduction in complex biofluids

Karim, A. M. (2026) · Journal of Applied Physics · doi:10.1063/5.0339038

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

Singh, R. K., Sagar, V., Kurian, A. G., Jain, S. K., Kim, H. S., & Kim, H. (2026) · BMEMat · doi:10.1002/bmm2.70126

Reformulating Time-Cure Superposition to Describe the Phase Transition in Rearranging Gel Networks

Khare, G. V., Anseth, K. S., & Schultz, K. M. (2026) · ACS Macro Letters · doi:10.1021/acsmacrolett.6c00379

A Combinatorial Approach to the Design of Boronate Ester Hydrogels Reveals the Remarkable Binding Properties of a Bicyclic Diol

Terriac, L., Alsabil, K., Saint‐Pé, G., Viault, G., Maugars, Y., Garnier, C., Hélesbeux, J., & Delplace, V. (2026) · Chemistry of Materials · doi:10.1021/acs.chemmater.6c01255

Architected 3D-printable hydrogels with amplified piezoionic transduction for self-powered wearables

Belduque, M. J. A., Mogli, G., Sacco, A., Roppolo, I., & Stassi, S. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.182105

Effect of hydrogel properties on fibroblast morphodynamics

Boroojeni, F. R., Reustle, N., Schoen, V., Naeimipour, S., Junker, J. P. E., Pagella, P., & Aili, D. (2026) · Biomaterials Advances · doi:10.1016/j.bioadv.2026.215192

IPN Hydrogel Mimicking ECM Structure for Osteochondral Tissue Engineering

Otsuka, H. (2026) · Springer eBooks · doi:10.1007/978-3-031-80976-7_7-1

AM for liver tissue engineering

Sekar, J. A., Kripamol, R., Suresh, S., Philips, C. A., Amrutha, C., Suku, S., Shenoy, S. J., & Kumar, P. R. A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33889-2.00004-2

Minimally Invasive In Vivo Fabrication of Multiscale Biohybrid Systems

Ge, Z., Gao, Y., Junyuan, E. C., Le, T. D., Lanfeng, L., Zhang, Y., & Lim, C. T. (2026) · Advanced Materials · doi:10.1002/adma.75421

Modelling glioblastoma with organoids and assembloids: Opportunities and challenges

Yüksel, B., Doğan, A., & Şahin, F. (2026) · Medical Oncology · doi:10.1007/s12032-026-03472-7

Viscoelastic Cell Microenvironment: Hydrogel‐Based Strategy for Recapitulating Dynamic ECM Mechanics

Ma, Y., Han, T., Yang, Q., Wang, J., Feng, B., Jia, Y., Zhao, W., & Xu, F. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202100848 · Cited by 215

Hydrogels mimicking the viscoelasticity of extracellular matrix for regenerative medicine: Design, application, and molecular mechanism

Li, L., Wang, S., Chen, Y., Dong, S., Zhang, C., Liao, L., & Zhang, W. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155206 · Cited by 40

Dynamic Hydrogels with Viscoelasticity and Tunable Stiffness for the Regulation of Cell Behavior and Fate

Zhang, Y., Wang, Z., Sun, Q., Li, Q., Li, S., & Li, X. (2023) · Materials · doi:10.3390/ma16145161 · Cited by 70

Effects of extracellular matrix viscoelasticity on cellular behaviour

Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224

Stress relaxing hyaluronic acid-collagen hydrogels promote cell spreading, fiber remodeling, and focal adhesion formation in 3D cell culture

Lou, J., Stowers, R. S., Nam, S., Xia, Y., & Chaudhuri, O. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.004 · Cited by 540