Viscoelastic hydrogels for 3D cell culture

Atomic Force Microscope

Binnig, G. K., Quate, C. F., & Gerber, C. (1986) · Physical Review Letters · doi:10.1103/physrevlett.56.930 · Cited by 14,795

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915

The Theory of Polymer Dynamics

Marrucci, G. (1987) · Journal of Non-Newtonian Fluid Mechanics · doi:10.1016/0377-0257(87)85036-x · Cited by 10,051

The theory of polymer dynamics

Doi, M., & Edwards, S. F. (1986) · Cited by 8,964

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382

Biomechanics. Mechanical Properties of Living Tissues

Fung, Y. C., & Skalak, R. (1982) · Journal of Applied Mechanics · doi:10.1115/1.3162171 · Cited by 6,040

Hydrogels for Tissue Engineering

Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,295

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551

Tensional homeostasis and the malignant phenotype

Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.010 · Cited by 3,941

Force measurements with the atomic force microscope: Technique, interpretation and applications

Butt, H., Cappella, B., & Kappl, M. (2005) · Surface Science Reports · doi:10.1016/j.surfrep.2005.08.003 · Cited by 3,807

Cell locomotion and focal adhesions are regulated by substrate flexibility

Pelham, R. J., & Wang, Y. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13661 · Cited by 3,082

Taking Cell-Matrix Adhesions to the Third Dimension

Cukierman, E., Pankov, R., Stevens, D. R., & Yamada, K. M. (2001) · Science · doi:10.1126/science.1064829 · Cited by 3,027

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Chaudhuri, O., Gu, L., Klumpers, D., Darnell, M., Bencherif, S. A., Weaver, J. C., Huebsch, N., Lee, H.-P., Lippens, E., Duda, G. N., et al. (2016) · Nature Materials · doi:10.1038/nmat4489 · Cited by 2,443

Alginate hydrogels as synthetic extracellular matrix materials

Rowley, J. A., Madlambayan, G., & Mooney, D. J. (1999) · Biomaterials · doi:10.1016/s0142-9612(98)00107-0 · Cited by 2,342

Local force and geometry sensing regulate cell functions

Vogel, V., & Sheetz, M. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1890 · Cited by 2,328

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., & Janmey, P. A. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20041 · Cited by 2,325

Hyaluronic Acid Hydrogels for Biomedical Applications

Burdick, J. A., & Prestwich, G. D. (2011) · Advanced Materials · doi:10.1002/adma.201003963 · Cited by 2,150

Biomechanics

Fung, Y. C. (1993) · Springer eBooks · doi:10.1007/978-1-4757-2257-4 · Cited by 2,092

A practical guide to hydrogels for cell culture

Caliari, S. R., & Burdick, J. A. (2016) · Nature Methods · doi:10.1038/nmeth.3839 · Cited by 2,075

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

Swift, J., Ivanovska, I. L., Buxboim, A., Harada, T., Dingal, P. C. D. P., Pinter, J., Pajerowski, J. D., Spinler, K. R., Shin, J., Tewari, M., et al. (2013) · Science · doi:10.1126/science.1240104 · Cited by 1,998

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

Wang, N., Tytell, J. D., & Ingber, D. E. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2594 · Cited by 1,815

Myotubes differentiate optimally on substrates with tissue-like stiffness

Engler, A. J., Griffin, M. A., Sen, S., Bönnemann, C. G., Sweeney, H. L., & Discher, D. E. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200405004 · Cited by 1,743

Integrin ligands at a glance

Humphries, J. D., Byron, A., & Humphries, M. J. (2006) · Journal of Cell Science · doi:10.1242/jcs.03098 · Cited by 1,711

Nonlinear elasticity in biological gels

Storm, C., Pastore, J. J., MacKintosh, F. C., Lubensky, T. C., & Janmey, P. A. (2005) · Nature · doi:10.1038/nature03521 · Cited by 1,707

Optical Measurements of Frequency-Dependent Linear Viscoelastic Moduli of Complex Fluids

Mason, T. G., & Weitz, D. A. (1995) · Physical Review Letters · doi:10.1103/physrevlett.74.1250 · Cited by 1,699

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

Huebsch, N., Arany, P. R., Mao, A. S., Shvartsman, D. E., Ali, O. A., Bencherif, S. A., Rivera‐Feliciano, J., & Mooney, D. J. (2010) · Nature Materials · doi:10.1038/nmat2732 · Cited by 1,613

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

Gilbert, P. M., Havenstrite, K. L., Magnusson, K. E. G., Sacco, A., Leonardi, N. A., Kraft, P., Nguyen, N. K., Thrun, S., Lutolf, M. P., & Blau, H. M. (2010) · Science · doi:10.1126/science.1191035 · Cited by 1,587

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

Grashoff, C., Hoffman, B. D., Brenner, M. D., Zhou, R., Parsons, M., Yang, M. T., McLean, M. A., Sligar, S. G., Chen, C. S., Ha, T., et al. (2010) · Nature · doi:10.1038/nature09198 · Cited by 1,549

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

Elsdale, T., & Bard, J. (1972) · The Journal of Cell Biology · doi:10.1083/jcb.54.3.626 · Cited by 1,527

Stretching Single Talin Rod Molecules Activates Vinculin Binding

Hernández, A. E. D. R., Pérez‐Jiménez, R., Liu, R., Roca‐Cusachs, P., Fernández, J. M., & Sheetz, M. P. (2009) · Science · doi:10.1126/science.1162912 · Cited by 1,492

Stresses at the Cell-to-Substrate Interface during Locomotion of Fibroblasts

Dembo, M., & Wang, Y. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77386-8 · Cited by 1,319

Elastic Behavior of Cross-Linked and Bundled Actin Networks

Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P. T., & Weitz, D. A. (2004) · Science · doi:10.1126/science.1095087 · Cited by 1,256

Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks

Zhao, X. (2013) · Soft Matter · doi:10.1039/c3sm52272e · Cited by 1,254

Activation of Integrin Function by Nanopatterned Adhesive Interfaces

Arnold, M., Cavalcanti‐Adam, E. A., Glass, R., Blümmel, J., Eck, W., Kantlehner, M., Kessler, H., & Spatz, J. P. (2004) · ChemPhysChem · doi:10.1002/cphc.200301014 · Cited by 1,165

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

Khetan, S., Güvendiren, M., Legant, W. R., Cohen, D. M., Chen, C. S., & Burdick, J. A. (2013) · Nature Materials · doi:10.1038/nmat3586 · Cited by 1,164

Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer

Nelson, C. M., & Bissell, M. J. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010305.104315 · Cited by 1,153

Substrate Compliance versus Ligand Density in Cell on Gel Responses

Engler, A. J., Bačáková, L., Newman, C., Hategan, A. P., Griffin, M. A., & Discher, D. E. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74140-5 · Cited by 1,127

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

PETERSEN, O. W., Rønnov‐Jessen, L., Howlett, A. R., & Bissell, M. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.19.9064 · Cited by 1,096

Fibroblast Adaptation and Stiffness Matching to Soft Elastic Substrates

Solon, J., Levental, I., Sengupta, K., Georges, P. C., & Janmey, P. A. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.101386 · Cited by 1,026

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

Kumar, S., & Weaver, V. M. (2009) · Cancer and Metastasis Reviews · doi:10.1007/s10555-008-9173-4 · Cited by 966

Cell adhesion and motility depend on nanoscale RGD clustering

Maheshwari, G., Brown, G., Lauffenburger, D. A., Wells, A. H., & Griffith, L. G. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.10.1677 · Cited by 951

Traction Dynamics of Filopodia on Compliant Substrates

Chan, C. E., & Odde, D. J. (2008) · Science · doi:10.1126/science.1163595 · Cited by 942

Soft biological materials and their impact on cell function

Levental, I., Georges, P. C., & Janmey, P. A. (2006) · Soft Matter · doi:10.1039/b610522j · Cited by 908

Substrate stress relaxation regulates cell spreading

Chaudhuri, O., Gu, L., Darnell, M., Klumpers, D. D., Bencherif, S. A., Weaver, J. C., Huebsch, N., & Mooney, D. J. (2015) · Nature Communications · doi:10.1038/ncomms7365 · Cited by 903

Particle Tracking Microrheology of Complex Fluids

Mason, T. G., Ganesan, K., van Zanten, J. H., Wirtz, D., & Kuo, S. C. (1997) · Physical Review Letters · doi:10.1103/physrevlett.79.3282 · Cited by 872

Solid stress inhibits the growth of multicellular tumor spheroids

Helmlinger, G., Netti, P. A., Lichtenbeld, H. C., Melder, R. J., & Jain, R. K. (1997) · Nature Biotechnology · doi:10.1038/nbt0897-778 · Cited by 859

Mechanotransduction in development: a growing role for contractility

Wozniak, M. A., & Chen, C. S. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2592 · Cited by 847

Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels

Bryant, S. J., & Anseth, K. S. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.1217 · Cited by 845

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Radmacher, M., Fritz, M., Kacher, C. M., Cleveland, J. P., & Hansma, P. K. (1996) · Biophysical Journal · doi:10.1016/s0006-3495(96)79602-9 · Cited by 839

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

Chaudhuri, O., Koshy, S. T., Branco da Cunha, C., Shin, J.-W., Verbeke, C. S., Allison, K. H., & Mooney, D. J. (2014) · Nature Materials · doi:10.1038/nmat4009 · Cited by 820

Measurement of Local Viscoelasticity and Forces in Living Cells by Magnetic Tweezers

Bausch, A. R., Möller, W., & Sackmann, E. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77225-5 · Cited by 797

The design of reversible hydrogels to capture extracellular matrix dynamics

Rosales, A. M., & Anseth, K. S. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2015.12 · Cited by 770

Neurite branching on deformable substrates

Flanagan, L. A., Ju, Y. S., Marg, B., Osterfield, M., & Janmey, P. A. (2002) · Neuroreport · doi:10.1097/00001756-200212200-00007 · Cited by 759

Microrheology of Human Lung Epithelial Cells Measured by Atomic Force Microscopy

Alcaraz, J., Buscemi, L., Grabulosa, M., Trepat, X., Fabry, B., Farré, R., & Navajas, D. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)75014-0 · Cited by 745

Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering

Wang, H., & Heilshorn, S. C. (2015) · Advanced Materials · doi:10.1002/adma.201501558 · Cited by 736

Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering

Mann, B. K., Gobin, A. S., Tsai, A. T., Schmedlen, R. H., & West, J. L. (2001) · Biomaterials · doi:10.1016/s0142-9612(01)00051-5 · Cited by 709

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

Baker, B. M., Trappmann, B., Wang, W. Y., Sakar, M. S., Kim, I. L., Shenoy, V. B., Burdick, J. A., & Chen, C. S. (2015) · Nature Materials · doi:10.1038/nmat4444 · Cited by 556

Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor ProgressionPreprint

Schedin, P. S., & Keely, P. J. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003228 · Cited by 536

Cell‐Responsive Synthetic Hydrogels

Lütolf, M. P., Raeber, G. P., Zisch, A. H., Tirelli, N., & Hubbell, J. A. (2003) · Advanced Materials · doi:10.1002/adma.200304621 · Cited by 526

Scanning Probe-Based Frequency-Dependent Microrheology of Polymer Gels and Biological Cells

Mahaffy, R. E., Shih, C.-K. K., MacKintosh, F. C., & Käs, J. A. (2000) · Physical Review Letters · doi:10.1103/physrevlett.85.880 · Cited by 509

Mimicking biological functionality with polymers for biomedical applications

Green, J. J., & Elisseeff, J. H. (2016) · Nature · doi:10.1038/nature21005 · Cited by 501

Viscoelastic Properties of Living Embryonic Tissues: a Quantitative Study

Forgács, G., Foty, R. A., Shafrir, Y., & Steinberg, M. S. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77932-9 · Cited by 498

Mechanical Properties of Cellularly Responsive Hydrogels and Their Experimental Determination

Kloxin, A. M., Kloxin, C. J., Bowman, C. N., & Anseth, K. S. (2010) · Advanced Materials · doi:10.1002/adma.200904179 · Cited by 477

The influence of substrate creep on mesenchymal stem cell behaviour and phenotype

Cameron, A. R., Frith, J. E., & Cooper-White, J. J. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.04.003 · Cited by 437

Two-dimensional mechanical properties of rabbit skin—I. Experimental system

Lanir, Y., & Fung, Y. C. (1974) · Journal of Biomechanics · doi:10.1016/0021-9290(74)90067-0 · Cited by 425

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

Klein, E. A., Yin, L., Kothapalli, D., Castagnino, P. A., Byfield, F. J., Xu, T., Levental, I., Hawthorne, E. A., Janmey, P. A., & Assoian, R. K. (2009) · Current Biology · doi:10.1016/j.cub.2009.07.069 · Cited by 421

Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems

McKinnon, D. D., Domaille, D. W., Cha, J. N., & Anseth, K. S. (2013) · Advanced Materials · doi:10.1002/adma.201303680 · Cited by 417

Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water

Brown, A. E., Игоревич, Л. Р., Discher, D. E., Purohit, P. K., & Weisel, J. W. (2009) · Science · doi:10.1126/science.1172484 · Cited by 416

Reversible stress softening of actin networks

Chaudhuri, O., Parekh, S. H., & Fletcher, D. A. (2007) · Nature · doi:10.1038/nature05459 · Cited by 407

Biomaterials and emerging anticancer therapeutics: engineering the microenvironment

Gu, L., & Mooney, D. J. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2015.3 · Cited by 407

Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels

Das, R. K., Gocheva, V., Hammink, R., Zouani, O. F., & Rowan, A. E. (2015) · Nature Materials · doi:10.1038/nmat4483 · Cited by 407

Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels

Mahoney, M. J., & Anseth, K. S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.11.007 · Cited by 377

Stress-relaxation behavior in gels with ionic and covalent crosslinks

Zhao, X., Huebsch, N., Mooney, D. J., & Suo, Z. (2010) · Journal of Applied Physics · doi:10.1063/1.3343265 · Cited by 375

Determining Microscopic Viscoelasticity in Flexible and Semiflexible Polymer Networks from Thermal Fluctuations

Schnurr, B., Gittes, F., MacKintosh, F. C., & Schmidt, C. F. (1997) · Macromolecules · doi:10.1021/ma970555n · Cited by 371

In vivo quantification of spatially varying mechanical properties in developing tissues

Serwane, F., Mongera, A., Rowghanian, P., Kealhofer, D., Lucio, A. A., Hockenbery, Z. M., & Campàs, O. (2016) · Nature Methods · doi:10.1038/nmeth.4101 · Cited by 370

The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells

Peyton, S. R., Raub, C. B., Keschrumrus, V., & Putnam, A. J. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.05.012 · Cited by 357

Two-dimensional mechanical properties of rabbit skin—II. Experimental results

Lanir, Y., & Fung, Y. C. (1974) · Journal of Biomechanics · doi:10.1016/0021-9290(74)90058-x · Cited by 354

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

Nam, S., Hu, K. H., Butte, M. J., & Chaudhuri, O. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1523906113 · Cited by 342

Creep and relaxation of nonlinear viscoelastic materials

Saunders, D. W. (1978) · Polymer · doi:10.1016/0032-3861(78)90187-8 · Cited by 340

MR elastography of breast lesions: Understanding the solid/liquid duality can improve the specificity of contrast‐enhanced MR mammography

Sinkus, R., Siegmann, K., Xydeas, T., Tanter, M., Claussen, C. D., & Fink, M. (2007) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21404 · Cited by 332

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

Fischbach, C., Kong, H. J., Hsiong, S. X., Evangelista, M. B., Yuen, W. W., & Mooney, D. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808932106 · Cited by 315

FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness

Kong, H. J., Polte, T. R., Alsberg, E., & Mooney, D. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405873102 · Cited by 308

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

Münster, S., Jawerth, L. M., Leslie, B. A., Weitz, J. I., Fabry, B., & Weitz, D. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222787110 · Cited by 281

Linear viscoelastic behavior of subcutaneous adipose tissue

Geerligs, M., Peters, G. G., Ackermans, P. A. J., Oomens, C. W. J., & Baaijens, F. F. (2008) · Biorheology · doi:10.3233/bir-2008-0517 · Cited by 221

Diffusing Wave Spectroscopy Microrheology of Actin Filament Networks

Palmer, A. F., Mason, T. G., Xu, J., Kuo, S. C., & Wirtz, D. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77271-1 · Cited by 220

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

Schultz, K. M., Kyburz, K. A., & Anseth, K. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511304112 · Cited by 216

Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells

Nam, S., Lee, J. Y., Brownfield, D., & Chaudhuri, O. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2016.10.002 · Cited by 203

Roles of Mechanical Forces and Collagen Failure in the Development of Elastase-induced Emphysema

KONONOV, S., Brewer, K. K., Sakai, H., Cavalcante, F. S. Á., SABAYANAGAM, C. R., Ingenito, E. P., & Suki, B. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.10.2101083 · Cited by 189

On the viscoelastic character of liver tissue: experiments and modelling of the linear behaviour

Liu, Z., & Bilston, L. E. (2000) · Biorheology · doi:10.1177/0006355x2000037003002 · Cited by 188

Passive and active microrheology with optical tweezers

Brau, R. R., Ferrer, J. M., Lee, H., Castro, C. E., Tam, B. K., Tarsa, P. B., Matsudaira, P. T., Boyce, M. C., Kamm, R. D., & Lang, M. J. (2007) · Journal of Optics A Pure and Applied Optics · doi:10.1088/1464-4258/9/8/s01 · Cited by 175

Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension

Parekh, S. H., Chatterjee, K., Lin‐Gibson, S., Moore, N. M., Cicerone, M. T., Young, M. F., & Simon, C. G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.11.065 · Cited by 126

A simple indentation device for measuring micrometer-scale tissue stiffness

Levental, I., Levental, K. R., Klein, E. A., Assoian, R. K., Miller, R. T., Wells, R. G., & Janmey, P. A. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/19/194120 · Cited by 120

Rheology of fibrin clots. I.

Roberts, W. W., Kramer, O., Rosser, R. W., Nestler, F. H. M., & Ferry, J. D. (1974) · Biophysical Chemistry · doi:10.1016/0301-4622(74)80002-5 · Cited by 118

Gelation of Covalently Cross-Linked PEG−Heparin Hydrogels

Schultz, K. M., Baldwin, A. D., Kiick, K. L., & Furst, E. M. (2009) · Macromolecules · doi:10.1021/ma900766u · Cited by 103

Programming Molecular Association and Viscoelastic Behavior in Protein Networks

Dooling, L. J., Buck, M. E., Zhang, W., & Tirrell, D. A. (2016) · Advanced Materials · doi:10.1002/adma.201506216 · Cited by 103

Cellular Dynamics

Weiss, P. A. (1959) · Reviews of Modern Physics · doi:10.1103/revmodphys.31.11 · Cited by 85

New advances in probing cell–extracellular matrix interactions

Liu, A. P., Chaudhuri, O., & Parekh, S. H. (2017) · Integrative Biology · doi:10.1039/c6ib00251j · Cited by 76

Inelastic behaviour of collagen networks in cell–matrix interactions and mechanosensation

Mohammadi, H., Arora, P. D., Simmons, C. A., Janmey, P. A., & McCulloch, C. A. (2014) · Journal of The Royal Society Interface · doi:10.1098/rsif.2014.1074 · Cited by 66

Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology

Staunton, J. R., Vieira, W. D., Fung, K. L., Lake, R. G., Devine, A., & Tanner, K. (2016) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-016-0460-9 · Cited by 63

Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging

Kotlarchyk, M. A., Botvinick, E. L., & Putnam, A. J. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/19/194121 · Cited by 40

Early fracture callus displays smooth muscle‐like viscoelastic properties ex vivo: Implications for fracture healing

McDonald, S. J., Dooley, P. C., McDonald, A. C., Schuijers, J. A., Ward, A. R., & Grills, B. L. (2009) · Journal of Orthopaedic Research® · doi:10.1002/jor.20923 · Cited by 19

Why do phospholipid polymers reduce protein adsorption?

Ishihara, K., Nomura, H., Mihara, T., Kurita, K., Iwasaki, Y., & Nakabayashi, N. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199802)39:2

Polymeric tissue adhesives

Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764

Towards organoid culture without Matrigel

Kozlowski, M. T., Crook, C. J., & Ku, H. T. (2021) · Communications Biology · doi:10.1038/s42003-021-02910-8 · Cited by 409

Structurally Dynamic Hydrogels for Biomedical Applications: Pursuing a Fine Balance between Macroscopic Stability and Microscopic Dynamics

Zhang, K., Feng, Q., Fang, Z., Gu, L., & Bian, L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00071 · Cited by 401

Carbohydrate-Based Macromolecular Biomaterials

Su, L., Feng, Y., Wei, K., Xu, X., Liu, R., & Chen, G. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01338 · Cited by 342

Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies

Nam, S., Stowers, R. S., Lou, J., Xia, Y., & Chaudhuri, O. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.02.004 · Cited by 303

Viscoelastic Cell Microenvironment: Hydrogel‐Based Strategy for Recapitulating Dynamic ECM Mechanics

Ma, Y., Han, T., Yang, Q., Wang, J., Feng, B., Jia, Y., Zhao, W., & Xu, F. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202100848 · Cited by 215

Hydrogels mimicking the viscoelasticity of extracellular matrix for regenerative medicine: Design, application, and molecular mechanism

Li, L., Wang, S., Chen, Y., Dong, S., Zhang, C., Liao, L., & Zhang, W. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155206 · Cited by 40

Dynamic Hydrogels with Viscoelasticity and Tunable Stiffness for the Regulation of Cell Behavior and Fate

Zhang, Y., Wang, Z., Sun, Q., Li, Q., Li, S., & Li, X. (2023) · Materials · doi:10.3390/ma16145161 · Cited by 70

Effects of extracellular matrix viscoelasticity on cellular behaviour

Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224

Stress relaxing hyaluronic acid-collagen hydrogels promote cell spreading, fiber remodeling, and focal adhesion formation in 3D cell culture

Lou, J., Stowers, R. S., Nam, S., Xia, Y., & Chaudhuri, O. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.004 · Cited by 540