The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles
Open accessAbstract
The biomolecular corona promotes a switch of both the cell entry mechanism and the intracellular dynamics of liposomes.
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“Considering that apolipoproteins on nanoparticle play an important role in association with cellular uptake to target cells32–34, targeting capability of PCSN partly could be linked with some serum proteins recruited at the surface of PCSN.”
From Cloaking nanoparticles with protein corona shield for targeted drug delivery. (2018) · cites this paper as [34]
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Cites
A guided tour into subcellular colocalization analysis in light microscopy
Bolte, S., & Cordelières, F. P. (2006) · Journal of Microscopy · doi:10.1111/j.1365-2818.2006.01706.x · Cited by 5,506
Cellular uptake of nanoparticles: Journey inside the cell
Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., Brown, D., Alkilany, A. M., Farokhzad, O. C., & Mahmoudi, M. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00636a · Cited by 2,859
Self-citationMaesschalck, R. D., Jouan-Rimbaud, D., & Massart, D. L. (2000) · Chemometrics and Intelligent Laboratory Systems · doi:10.1016/s0169-7439(99)00047-7 · Cited by 2,336
Measurement of co‐localization of objects in dual‐colour confocal images
Manders, E. M. M., Verbeek, F. J., & Aten, J. A. (1993) · Journal of Microscopy · doi:10.1111/j.1365-2818.1993.tb03313.x · Cited by 2,132
A practical guide to evaluating colocalization in biological microscopy
Dunn, K. W., Kamocka, M. M., & McDonald, J. H. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00462.2010 · Cited by 2,012
Salvati, A., Pitek, A. S., Monopoli, M. P., Prapainop, K., Bombelli, F. B., Hristov, D. R., Kelly, P. M., Åberg, C., Mahon, E., & Dawson, K. A. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2012.237 · Cited by 1,912
Walkey, C. D., & Chan, W. C. W. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15233e · Cited by 1,758
Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System
Goldstein, J. L., Brown, M. S., Anderson, R. G. W., Russell, D. W., & Schneider, W. J. (1985) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.01.110185.000245 · Cited by 1,600
Adler, J., & Parmryd, I. (2010) · Cytometry Part A · doi:10.1002/cyto.a.20896 · Cited by 1,097
Rejman, J., Bragonzi, A., & Conese, M. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.03.038 · Cited by 851
Cited by
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The Crown and the Scepter: Roles of the Protein Corona in Nanomedicine
Cai, R., & Chen, C. (2018) · Advanced Materials · doi:10.1002/adma.201805740 · Cited by 610
Cloaking nanoparticles with protein corona shield for targeted drug delivery.
Oh, J. Y., Kim, H. S., Palanikumar, L., Go, E. M., Jana, B., Park, S. A., Kim, H. Y., Kim, K., Seo, J. K., Kwak, S. K., et al. (2018) · Nature communications · doi:10.1038/s41467-018-06979-4 · Cited by 409
Yamashita, T., Takahashi, Y., & Takakura, Y. (2018) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b18-00133 · Cited by 309
Corona Composition Can Affect the Mechanisms Cells Use to Internalize Nanoparticles
Francia, V., Yang, K., Deville, S., Reker‐Smit, C., Nelissen, I., & Salvati, A. L. (2019) · ACS Nano · doi:10.1021/acsnano.9b03824 · Cited by 312
Gandek, T. B., van der Koog, L., & Nagelkerke, A. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300319 · Cited by 256
Metadata
- Authors
- Digiacomo, L., Cardarelli, F., Pozzi, D., Palchetti, S., Digman, M. A., Gratton, E., Capriotti, A. L., Mahmoudi, M., & Caracciolo, G.
- Affiliations
- Università di Camerino (IT)
- Scuola Normale Superiore (IT)
- Sapienza University of Rome (IT)
- University of California, Irvine (US)
- Brigham and Women's Hospital (US)
- Corresponding author
- Mahmoudi, M.
- Caracciolo, G.
- ORCID
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2017
- Volume
- 9
- Issue
- 44
- Pages
- 17254-17262
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- PMC
- PMC5700750
- OpenAlex
- W2766823924
- Cited by
- 109
- References
- 52
- Citations by year
- 2026: 15 · 2025: 11 · 2024: 9 · 2023: 11 · 2022: 12 · 2021: 8 · 2020: 13 · 2019: 18 · 2018: 12
- FWCI
- 4.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Nanoscale (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, other-oa)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Scuola Normale Superiore di Pisa (submittedVersion, other-oa)
- Funders
- National Institutes of Health (NIH P50, NIH‐P50 GM076516, GM-076516, NIH P41-GM103540, GM103540)
- National Institute of General Medical Sciences (P41GM103540, P50GM076516)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Keywords
- biomolecular corona, apolipoproteins, lipid nanoparticles, cellular uptake, macropinocytosis, clathrin-mediated endocytosis, intracellular trafficking, LDL receptor, HeLa cells, plasma exposure, targeted delivery
- MeSH terms
- Protein Corona, Apolipoproteins, Endocytosis, HeLa Cells, Humans, Lipids, Pinocytosis, Tissue Distribution, Drug Delivery Systems, Nanoparticles
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