The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production
Abstract
This tutorial review covers tools, strategies, and procedures of systems metabolic engineering facilitating the development of microbial cell factories efficiently producing chemicals and materials.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A protocol for generating a high-quality genome-scale metabolic reconstruction
Thiele, I., & Palsson, B. Ø. (2010) · Nature Protocols · doi:10.1038/nprot.2009.203 · Cited by 1,789
CRISPR-Cas guides the future of genetic engineering
Knott, G. J., & Doudna, J. A. (2018) · Science · doi:10.1126/science.aat5011 · Cited by 1,410
A Whole-Cell Computational Model Predicts Phenotype from Genotype
Karr, J. R., Sanghvi, J. C., Macklin, D. N., Gutschow, M. V., Jacobs, J. M., Bolival, B., Assad-Garcia, N., Glass, J. I., & Covert, M. W. (2012) · Cell · doi:10.1016/j.cell.2012.05.044 · Cited by 1,300
Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods
Lewis, N. E., Nagarajan, H., & Palsson, B. O. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2737 · Cited by 779
Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction
O'Brien, E. J., Lerman, J. A., Chang, R. L., Hyduke, D. R., & Palsson, B. Ø. (2013) · Molecular Systems Biology · doi:10.1038/msb.2013.52 · Cited by 471
Cited by
β-Ionone: Its Occurrence and Biological Function and Metabolic Engineering
Paparella, A., Shaltiel-Harpaza, L., & Ibdah, M. (2021) · Plants · doi:10.3390/plants10040754 · Cited by 155
Saravanan, A., Deivayanai, V. C., Senthil Kumar, P., Rangasamy, G., & Varjani, S. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.127982 · Cited by 69
Sahu, S., Kunj, P., Kaur, A., Khatri, M., Singh, G., & Arya, S. K. (2024) · Energy Conversion and Management · doi:10.1016/j.enconman.2024.118467 · Cited by 44
Xia, Y., Du, X., Liu, B., Guo, S., & Huo, Y.-X. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae429 · Cited by 31
Biosynthesis and bioactivities of triterpenoids from Centella asiatica: Challenges and opportunities
Zeng, W., Li, H., Liu, S., Luo, Z., Chen, J., & Zhou, J. (2025) · Biotechnology Advances · doi:10.1016/j.biotechadv.2025.108541 · Cited by 27
Wirth, N. T., & Nikel, P. I. (2021) · Chem Catalysis · doi:10.1016/j.checat.2021.09.002 · Cited by 26
Expanding catalytic versatility of modular polyketide synthases for alcohol biosynthesis
Yao, S., Xie, S., Liu, R.-Z., Huang, Z., & Zhang, L. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-01883-7 · Cited by 14
Johnson, Z., Anderson, D., Cheung, M. S., & Bohutskyi, P. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1569559 · Cited by 12
Metadata
- Authors
- Ko, Y.-S., Kim, J. W., Lee, J. A., Han, T., Kim, G. B., Park, J. E., & Lee, S. Y.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2020
- Volume
- 49
- Issue
- 14
- Pages
- 4615-4636
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W3036284296
- Cited by
- 476
- References
- 5
- FWCI
- 4.62
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.