Cited by 614Advancements in Transdermal Drug DeliveryNanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems

A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems

Open access
Duan, Yongtao, Dhar, Abhishek, Patel, Chetan, Khimani, Mehul, Neogi, Swarnali, Sharma, Prolay, Siva Kumar, Nadavala, Vekariya, Rohit L.·2020·RSC Advances

Abstract

Drug delivery technology has a wide spectrum, which is continuously being upgraded at a stupendous speed.

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Integrity signals

Registry

Crossref · 10.1039/d0ra03491f

Cites

117 of 117 references verified0 citation errors · 0 not checkable

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  • NLCs improve drug loading, stability, and release control.

    “SLNs, characterized by a solid lipid core stabilized with surfactants, provide high stability, reproducibility, and scalability, whereas NLCs, incorporating both solid and liquid lipids, improve drug loading, stability, and release control [29].”

    From Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies (2025) · cites this paper as [29]

    The Conclusion (page unavailable) says nanostructured lipid carriers may overcome the gelation tendency of SLNs, supporting a qualified stability benefit. The retrieved passages do not establish improved drug loading or release control for NLCs, or describe them as combining solid and liquid lipids. (LLM, conf=0.83)

    Experimental — accuracy not yet measured
  • SLNs provide high stability, reproducibility, and scalability.

    “SLNs, characterized by a solid lipid core stabilized with surfactants, provide high stability, reproducibility, and scalability, whereas NLCs, incorporating both solid and liquid lipids, improve drug loading, stability, and release control [29].”

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Cites

Flagged first, then by citations

1 of the 118 references couldn’t be matched to a known paper.

Research works printed but not linked: 14

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  10. Muhlen Z., Feste Lipid Nanopartikel mit prolongierter Wirkstoffliberation. Herstellung, Langzeitstabilitat, Charakterisierung, Freiset zungsverhalten und -mechanismen. PhD thesis, Freie Universitat Berlin, 1996 – from 1992-2 ref. no 2
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  14. Mehnert W. Meader K. Adv. Drug Deliv. Rev. 2001 47 165 196 10.1016/S0169-409X(01)00105-3 11311991 · DOI

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Authors
Duan, Y., Dhar, A., Patel, C., Khimani, M., Neogi, S., Sharma, P., Siva Kumar, N., & Vekariya, R. L.
Affiliations
  • Zhengzhou University (CN)
  • Jadavpur University (IN)
  • P P Savani University (IN)
  • Department of Chemical Engineering
  • Ton Duc Thang University (VN)
Corresponding author
Vekariya, Rohit L.
Venue
RSC Advances
Published
2020
Volume
10
Issue
45
Pages
26777-26791
ISSN
2046-2069 (ISSN-L)
OpenAlex
W3043255293
Cited by
614
References
118
Citations by year
2026: 68 · 2025: 119 · 2024: 139 · 2023: 126 · 2022: 98 · 2021: 58 · 2020: 6
FWCI
6.23
Type
journal article
Language
en
Open access
Locations
  • RSC Advances (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (81903623)
  • China Postdoctoral Science Foundation (2019M652586)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords
solid lipid nanoparticles, nanostructured lipid carriers, drug delivery systems, poorly water-soluble drugs, pharmacokinetics, liposomes, ethosomes, virosomes, deformable liposomes, surfactants, lipid excipients, nanoparticle stability, storage, theranostics

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