A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems
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Drug delivery technology has a wide spectrum, which is continuously being upgraded at a stupendous speed.
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NLCs improve drug loading, stability, and release control.
“SLNs, characterized by a solid lipid core stabilized with surfactants, provide high stability, reproducibility, and scalability, whereas NLCs, incorporating both solid and liquid lipids, improve drug loading, stability, and release control [29].”
From Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies (2025) · cites this paper as [29]
The Conclusion (page unavailable) says nanostructured lipid carriers may overcome the gelation tendency of SLNs, supporting a qualified stability benefit. The retrieved passages do not establish improved drug loading or release control for NLCs, or describe them as combining solid and liquid lipids. (LLM, conf=0.83)
Experimental — accuracy not yet measuredSLNs provide high stability, reproducibility, and scalability.
“SLNs, characterized by a solid lipid core stabilized with surfactants, provide high stability, reproducibility, and scalability, whereas NLCs, incorporating both solid and liquid lipids, improve drug loading, stability, and release control [29].”
From Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies (2025) · cites this paper as [29]
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- Authors
- Duan, Y., Dhar, A., Patel, C., Khimani, M., Neogi, S., Sharma, P., Siva Kumar, N., & Vekariya, R. L.
- Affiliations
- Zhengzhou University (CN)
- Jadavpur University (IN)
- P P Savani University (IN)
- Department of Chemical Engineering
- Ton Duc Thang University (VN)
- Corresponding author
- Vekariya, Rohit L.
- ORCID
- Venue
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2020
- Volume
- 10
- Issue
- 45
- Pages
- 26777-26791
- ISSN
- 2046-2069 (ISSN-L)
- PMC
- PMC9055574
- OpenAlex
- W3043255293
- Cited by
- 614
- References
- 118
- Citations by year
- 2026: 68 · 2025: 119 · 2024: 139 · 2023: 126 · 2022: 98 · 2021: 58 · 2020: 6
- FWCI
- 6.23
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- RSC Advances (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81903623)
- China Postdoctoral Science Foundation (2019M652586)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Keywords
- solid lipid nanoparticles, nanostructured lipid carriers, drug delivery systems, poorly water-soluble drugs, pharmacokinetics, liposomes, ethosomes, virosomes, deformable liposomes, surfactants, lipid excipients, nanoparticle stability, storage, theranostics
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