Where Is Nano Today and Where Is It Headed? A Review of Nanomedicine and the Dilemma of Nanotoxicology

Engineering precision nanoparticles for drug delivery

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Lipid nanoparticles for mRNA delivery

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Advances and Challenges of Liposome Assisted Drug Delivery

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Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children

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Lipid NanoparticlesFrom Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement

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Liposomal Formulations in Clinical Use: An Updated Review

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The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine

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Biodegradation, biodistribution and toxicity of chitosan

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Mechanisms of nanotoxicity: Generation of reactive oxygen species

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A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives

Liu, P., Chen, G., & Zhang, J. (2022) · Molecules · doi:10.3390/molecules27041372 · Cited by 1,334 · see citing works

Dendrimers: synthesis, applications, and properties

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Liposomes and polymersomes: a comparative review towards cell mimicking

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The big picture on nanomedicine: the state of investigational and approved nanomedicine products

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Organs-on-chips: into the next decade

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A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

Maschmeyer, I., Lorenz, A. K., Schimek, K., Hasenberg, T., Ramme, A. P., Hübner, J., Lindner, M., Drewell, C., Bauer, S., Thomas, A., et al. (2015) · Lab on a Chip · doi:10.1039/c5lc00392j · Cited by 861 · see citing works

Nanomedicine: Principles, Properties, and Regulatory Issues

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In silico toxicology: computational methods for the prediction of chemical toxicity

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Iron Oxide Nanoparticles for Biomedical Applications: A Perspective on Synthesis, Drugs, Antimicrobial Activity, and Toxicity

Arias, L. S., Pessan, J. P., Vieira, A. P. M., de Lima, T. M. T., Delbem, A. C. B., & Monteiro, D. R. (2018) · Antibiotics · doi:10.3390/antibiotics7020046 · Cited by 718 · see citing works

The journey of a drug-carrier in the body: An anatomo-physiological perspective

Bertrand, N., & Leroux, J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.09.098 · Cited by 713 · see citing works

Translational research: crossing the valley of death

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Microfluidic technologies for accelerating the clinical translation of nanoparticles

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The Impact of Nanoparticle Protein Corona on Cytotoxicity, Immunotoxicity and Target Drug Delivery

Corbo, C., Molinaro, R., Parodi, A., Furman, N. E. T., Salvatore, F., & Tasciotti, E. (2015) · Nanomedicine · doi:10.2217/nnm.15.188 · Cited by 704 · see citing works

Toxicology and clinical potential of nanoparticles

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Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects

Montoto, S. S., Muraca, G., & Ruiz, M. E. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.587997 · Cited by 672 · see citing works

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

Shah, P., Fritz, J. V., Glaab, E., Desai, M. S., Greenhalgh, K., Frachet, A., Niegowska, M., Estes, M., Jäger, C., Seguin-Devaux, C., et al. (2016) · Nature Communications · doi:10.1038/ncomms11535 · Cited by 660 · see citing works

Point-of-care diagnostics for infectious diseases: From methods to devices

Wang, C., Liu, M., Wang, Z., Song, L., Deng, Y., & He, N. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101092 · Cited by 627 · see citing works

Co-culture systems and technologies: taking synthetic biology to the next level

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A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems

Duan, Y., Dhar, A., Patel, C., Khimani, M., Neogi, S., Sharma, P., Siva Kumar, N., & Vekariya, R. L. (2020) · RSC Advances · doi:10.1039/d0ra03491f · Cited by 614 · see citing works

Polymeric nanoparticles: Promising platform for drug delivery

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Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

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Surface Modifications of Nanoparticles for Stability in Biological Fluids

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Carbon Nanodots Featuring Efficient FRET for Real‐Time Monitoring of Drug Delivery and Two‐Photon Imaging

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What do we (need to) know about the kinetic properties of nanoparticles in the body?

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Regulatory aspects on nanomedicines

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Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps

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Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics

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Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives

Navya, P. N., & Daima, H. K. (2016) · Nano Convergence · doi:10.1186/s40580-016-0064-z · Cited by 406 · see citing works

Challenges in nanomedicine clinical translation

Metselaar, J. M., & Lammers, T. (2020) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00740-5 · Cited by 405 · see citing works

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine

Fathi‐Achachelouei, M., Knopf‐Marques, H., da Silva, C. E. R., Barthès, J., Bat, E., Tezcaner, A., & Vrana, N. E. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00113 · Cited by 395 · see citing works

Nanoparticle-based drug delivery systems: a commercial and regulatory outlook as the field matures

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Quantitative Nanostructure−Activity Relationship Modeling

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Multiorgan-on-a-Chip: A Systemic Approach To Model and Decipher Inter-Organ Communication

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Carbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity

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Organ-on-a-chip platforms for studying drug delivery systems

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Immunological and Toxicological Considerations for the Design of Liposomes

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Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials

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Nanoemulsions for drug delivery

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Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

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A comprehensive review on recent preparation techniques of liposomes

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Nanomaterials for Nanotheranostics: Tuning Their Properties According to Disease Needs

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Microfluidic tools for cell biological research

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Experimental Considerations on The Cytotoxicity of Nanoparticles

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Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

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Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

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Physiologically Based Pharmacokinetic Modeling of Nanoparticles

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Lipid Nanoparticles as Carriers for Bioactive Delivery

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Role of Physicochemical Properties in Nanoparticle Toxicity

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Sentinel Lymph Node Imaging Using Quantum Dots in Mouse Tumor Models

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Solid lipid nanoparticles: a review on recent perspectives and patents

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Biomimetic Nanotechnology toward Personalized Vaccines

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Nanomedicine for tumor microenvironment modulation and cancer treatment enhancement

Liu, J., Chen, Q., Feng, L., & Liu, Z. (2018) · Nano Today · doi:10.1016/j.nantod.2018.06.008 · Cited by 329 · see citing works

A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents

Andra, V. V. S. N. L., Pammi, S. V. N., Bhatraju, L. V. K. P., & Ruddaraju, L. K. (2022) · BioNanoScience · doi:10.1007/s12668-022-00941-x · Cited by 327 · see citing works

Inorganic nanoparticles: A potential cancer therapy for human welfare

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Inorganic nanoparticles for biomedicine: where materials scientists meet medical research

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Blood-Brain Delivery Methods Using Nanotechnology

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Dendrimers as Pharmaceutical Excipients: Synthesis, Properties, Toxicity and Biomedical Applications

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Evidence-based approaches for the management of side-effects of adjuvant endocrine therapy in patients with breast cancer

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PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up

Operti, M. C., Bernhardt, A., Grimm, S., Engel, A., Figdor, C. G., & Tagit, O. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120807 · Cited by 302 · see citing works

Artemia salina as a model organism in toxicity assessment of nanoparticles

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In vivo evaluation of safety, biodistribution and pharmacokinetics of laser-synthesized gold nanoparticles

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Subchronic and chronic toxicity evaluation of inorganic nanoparticles for delivery applications

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The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

Cao, Y., Gong, Y. L., Liu, L., Zhou, Y., Fang, X., Zhang, C., Li, Y., & Li, J. (2017) · Journal of Applied Toxicology · doi:10.1002/jat.3470 · Cited by 282 · see citing works

Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury

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National Nanotechnology Initiative

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Recent Development of Inorganic Nanoparticles for Biomedical Imaging

Kim, D., Kim, J., Park, Y. I., Lee, N., & Hyeon, T. (2018) · ACS Central Science · doi:10.1021/acscentsci.7b00574 · Cited by 269 · see citing works

Nanoparticle–hydrogel superstructures for biomedical applications

Jiang, Y., Krishnan, N., Heo, J., Fang, R. H., & Zhang, L. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.05.041 · Cited by 268 · see citing works

Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer

Xiong, J., Wu, M., Chen, J., Liu, Y., Chen, Y., Fan, G., Liu, Y., Cheng, J., Wang, Z., Wang, S., et al. (2021) · ACS Nano · doi:10.1021/acsnano.1c07180 · Cited by 268 · see citing works

Microfluidic Sonication To Assemble Exosome Membrane-Coated Nanoparticles for Immune Evasion-Mediated Targeting

Liu, C., Zhang, W., Li, Y., Chang, J., Tian, F., Zhao, F., Ma, Y., & Sun, J. (2019) · Nano Letters · doi:10.1021/acs.nanolett.9b02841 · Cited by 267 · see citing works

Safety assessment of nanomaterials: Implications for nanomedicine

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Paediatric and geriatric drug delivery

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PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity

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Review of the effects of manufactured nanoparticles on mammalian target organs

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Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

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Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences

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Test No. 106: Adsorption -- Desorption Using a Batch Equilibrium Method

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In vitro approaches to assess the hazard of nanomaterials

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Intranasal COVID-19 vaccines: From bench to bed

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Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity

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The Design of Poly(lactide-co-glycolide) Nanocarriers for Medical Applications

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Factors Relating to the Biodistribution & Clearance of Nanoparticles & Their Effects on In Vivo Application

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Nanomaterial standards for efficacy and toxicity assessment

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Differential impact of endocrine therapy and chemotherapy on quality of life of breast cancer survivors: a prospective patient-reported outcomes analysis

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Simvastatin induced ferroptosis for triple-negative breast cancer therapy

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Inorganic nano-carriers based smart drug delivery systems for tumor therapy

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Cell Membrane-Coated Mimics: A Methodological Approach for Fabrication, Characterization for Therapeutic Applications, and Challenges for Clinical Translation

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Toxicity assessment of nanoparticles in various systems and organs

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