Biomaterial-based physical regulation of macrophage behaviour
Abstract
Macrophages respond to physical stimuli of biomaterials, including stiffness, topography and confinement. Understanding the mechanical regulation of macrophage behaviour provides insights for biomaterial design.
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Porosity and pore size represent other scaffold immunomodulatory features.
“Porosity and pore size represent other scaffold immunomodulatory features.”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [214]
Findings revealed that bigger pore size had a more pro-regenerative effect.
“Findings revealed that bigger pore size had a more pro-regenerative effect [214,215].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [214]
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Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Zhou, H., Xue, Y., Dong, L., & Wang, C.
- Affiliations
- University of Macau (MO)
- State Key Laboratory of Pharmaceutical Biotechnology (CN)
- Corresponding author
- Wang, Chunming
- Venue
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2021
- Volume
- 9
- Issue
- 17
- Pages
- 3608-3621
- ISSN
- 2050-750X (ISSN-L)
- 2050-7518
- OpenAlex
- W3139364974
- Cited by
- 47
- References
- 13
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 10 · 2023: 10 · 2022: 12 · 2021: 1
- FWCI
- 1.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry B (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Fundo para o Desenvolvimento das Ciências e da Tecnologia (0097/2019/A2, 0018/2019/AFJ)
- National Natural Science Foundation of China (32022088)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Keywords
- biomaterials, physical cues, mechanical regulation, substrate stiffness, surface topography, physical confinement, applied force, mechanotransduction, macrophage phenotype, biomaterial design, immune response to implants
- MeSH terms
- Animals, Biocompatible Materials, Extracellular Matrix, Humans, Macrophages, Models, Biological, Phenotype, Physical Stimulation, Mechanotransduction, Cellular, Mechanical Phenomena, Cellular Microenvironment
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