The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation
Abstract
Pdcd4 (programmed cell death 4) has been known as a tumour suppressor gene and potential target for anticancer therapies for several years. Initially, Pdcd4 was identified as a gene that is up‐regulated during apoptosis, but its precise role still remains to be defined. However, there is increasing evidence that Pdcd4 levels influence transcription, as well as translation, modulate different signal transduction pathways and might act as a tumour suppressor. Interestingly, recent data suggest that Pdcd4 function may depend on cell type and/or genetic background. This review summarizes the current knowledge regarding the function and regulation of Pdcd4.
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Cited by
Protein arginine methyltransferases and cancer
Yang, Y., & Bedford, M. T. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3409 · Cited by 1,083
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Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo
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miR-155 Regulated Inflammation Response by the SOCS1-STAT3-PDCD4 Axis in Atherogenesis
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LIANG, X., XU, Z., YUAN, M., ZHANG, Y., ZHAO, B., WANG, J., ZHANG, A., & LI, G. (2016) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2016.2497 · Cited by 99
Metadata
- Authors
- Lankat‐Buttgereit, B., & Göke, R.
- Venue
- Biology of the Cell
- Publisher
- Wiley
- Published
- 2009-06
- Volume
- 101
- Issue
- 6
- Pages
- 309-317
- ISSN
- 0248-4900 (ISSN-L)
- 1768-322X
- OpenAlex
- W1973921593
- Cited by
- 311
- References
- 24
- FWCI
- 10.44
- Type
- journal article
- Language
- en
- Open access
- closed
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