The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse
Open accessAbstract
Exogenous superoxide dismutase, catalase and scavengers of the hydroxyl radical protect pancreatic-islet cells against the toxic actions of alloxan in vitro [Grankvist et al. (1979) Biochem. J. 182, 17--25]. To test whether the extraordinary sensitivity of islet cells to alloxan is due to a deficiency of endogenous enzymes protecting against oxygen-reduction products, we assayed CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in mouse islets and other tissues. To correct for any blood contamination, haemoglobin was also measured in the tissue samples. Pancreatic islets were found to belong to tissues with relatively little activity of the protective enzymes. However, the deviation from other tissues in this respect is probably not large enough to explain the especially great susceptibility of islet cells to alloxan.
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Cites
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Mitochondrial Superoxide Dismutase
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Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex
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Metadata
- Authors
- Grankvist, K., Marklund, S. L., & Täljedal, I. B.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1981-11-01
- Volume
- 199
- Issue
- 2
- Pages
- 393-398
- ISSN
- 0264-6021 (ISSN-L)
- OpenAlex
- W1904188511
- Cited by
- 517
- References
- 35
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Grankvist, K., Marklund, S. L., & Täljedal, I. B. (1981). CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochemical Journal. https://doi.org/10.1042/bj1990393
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