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Cited by 517

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse

Open access
Grankvist, K, Marklund, S L, Täljedal, I B·1981·Biochemical Journal

Abstract

Exogenous superoxide dismutase, catalase and scavengers of the hydroxyl radical protect pancreatic-islet cells against the toxic actions of alloxan in vitro [Grankvist et al. (1979) Biochem. J. 182, 17--25]. To test whether the extraordinary sensitivity of islet cells to alloxan is due to a deficiency of endogenous enzymes protecting against oxygen-reduction products, we assayed CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in mouse islets and other tissues. To correct for any blood contamination, haemoglobin was also measured in the tissue samples. Pancreatic islets were found to belong to tissues with relatively little activity of the protective enzymes. However, the deviation from other tissues in this respect is probably not large enough to explain the especially great susceptibility of islet cells to alloxan.

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Metadata

Authors
Grankvist, K., Marklund, S. L., & Täljedal, I. B.
Venue
Biochemical Journal
Published
1981-11-01
Volume
199
Issue
2
Pages
393-398
ISSN
0264-6021 (ISSN-L)
OpenAlex
W1904188511
Cited by
517
References
35
FWCI
1.86
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. https://app.cochat.ai/papers/10.1042/bj1990393
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Grankvist, K., Marklund, S. L., & Täljedal, I. B. (1981). CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochemical Journal. https://doi.org/10.1042/bj1990393

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