Antioxidant and bioenergetic coupling between neurons and astrocytes

How mitochondria produce reactive oxygen species

Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196

Ischemic Cell Death in Brain Neurons

Lipton, P. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1431 · Cited by 3,043

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Pellerin, L., & Magistretti, P. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.22.10625 · Cited by 2,927

Nitric oxide synthases in mammals

Knowles, R. G., & Moncada, S. (1994) · Biochemical Journal · doi:10.1042/bj2980249 · Cited by 2,752

Oxidative stress and neurodegeneration: where are we now?

Halliwell, B. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03907.x · Cited by 2,614

Molecular dissection of reactive astrogliosis and glial scar formation

Sofroniew, M. V. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.08.002 · Cited by 2,594

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

Garthwaite, J., Charles, S. L., & Chess‐Williams, R. (1988) · Nature · doi:10.1038/336385a0 · Cited by 2,540

Glial and neuronal control of brain blood flow

Attwell, D., Buchan, A. M., Charpak, S., Lauritzen, M., MacVicar, B. A., & Newman, E. A. (2010) · Nature · doi:10.1038/nature09613 · Cited by 2,511

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

Barnett, D., Zimmer, T. S., Booraem, C., Palaguachi, F., Meadows, S. M., Xiao, H., Wong, M. Y., Luo, W., Gan, L., Chouchani, E. T., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01390-y · Cited by 41

Modulation of copper accumulation and copper-induced toxicity by antioxidants and copper chelators in cultured primary brain astrocytes

Bulcke, F., Santofimia‐Castaño, P., Gonzalez-Mateos, A., & Dringen, R. (2015) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2015.07.001 · Cited by 36

Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates

Netzahualcoyotzi, C., & Tapia, R. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0205-3 · Cited by 35

Nucleotide excision repair in chronic neurodegenerative diseases

Sepe, S., Payán‐Gómez, C., Milanese, C., Hoeijmakers, J. H. J., & Mastroberardino, P. G. (2013) · DNA repair · doi:10.1016/j.dnarep.2013.04.009 · Cited by 35

Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia

Vetrovoy, O. V., Sarieva, K., Lomert, E. V., Nimiritsky, P., Eschenko, N., Galkina, O., Lyanguzov, A. Y., Tyulkova, E. I., & Rybnikova, E. A. (2019) · Journal of Molecular Neuroscience · doi:10.1007/s12031-019-01469-8 · Cited by 33

Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology andS-(De)nitrosylation: Implications in Cancer and Neurodegeneration

Giacomo, G. D., Rizza, S., Montagna, C., & Filomeni, G. (2012) · International Journal of Cell Biology · doi:10.1155/2012/361872 · Cited by 33

Astroglial functions

Verkhratsky, A., & Butt, A. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821565-4.00008-0 · Cited by 31

Glutathione depletion: Starting point of brain metabolic stress, neuroinflammation and cognitive impairment in rats

González-Fraguela, M. E., Blanco, L., Fernández, C. I., Lorigados, L., Serrano, T., & Fernández, J. L. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.11.015 · Cited by 32

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes

Shim, M. S., Keun-young Kim, A., Bu, J. H., Nam, H. S., Jeong, S., Park, T. L., Ellisman, M. H., Weinreb, R. N., & Ju, W. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0171-8 · Cited by 32

Antidepressant-like responses in the forced swimming test elicited by glutathione and redox modulation

Rosa, J. M., Dafré, A. L., & Rodrigues, A. L. S. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.07.009 · Cited by 32

Endogenous Expression of ODN-Related Peptides in Astrocytes Contributes to Cell Protection Against Oxidative Stress: Astrocyte-Neuron Crosstalk Relevance for Neuronal Survival

Ghouili, I., Bahdoudi, S., Morin, F., Amri, F., Hamdi, Y., Coly, P., Walet-Balieu, M.-L., Leprince, J., Zekri, S., Vaudry, H., et al. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0630-3 · Cited by 38

Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation

Díaz‐Amarilla, P., Miquel, E., Trostchansky, A., Trías, E., Ferreira, A. M., Freeman, B. Α., Cassina, P., Barbeito, L., Vargas, M. R., & Rubbo, H. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.03.013 · Cited by 32

Sleep, mood disorders, and the ketogenic diet: potential therapeutic targets for bipolar disorder and schizophrenia

Choi, J., Kang, J., Kim, T., & Nehs, C. J. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1358578 · Cited by 37

Female sex steroids and glia cells: Impact on multiple sclerosis lesion formation and fine tuning of the local neurodegenerative cellular network

Kipp, M., Hochstrasser, T., Schmitz, C., & Beyer, C. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.11.016 · Cited by 32

Intertwined ROS and Metabolic Signaling at the Neuron-Astrocyte Interface

Vicente‐Gutiérrez, C., Jiménez-Blasco, D., & Quintana–Cabrera, R. (2020) · Neurochemical Research · doi:10.1007/s11064-020-02965-9 · Cited by 31

The Role Of Glial–Neuronal Metabolic Cooperation in Modulating Progression of Multiple Sclerosis and Neuropathic Pain

Robinson, R. R., Dietz, A. K., Maroof, A. M., Asmis, R., & Forsthuber, T. G. (2019) · Immunotherapy · doi:10.2217/imt-2018-0153 · Cited by 33

Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis

Benson, B. C., Shaw, P. J., Azzouz, M., Highley, J. R., & Hautbergue, G. M. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.783624 · Cited by 30

Metabolic Features of Brain Function with Relevance to Clinical Features of Alzheimer and Parkinson Diseases

Butterfield, D. A., Favia, M., Spera, I., Campanella, A., Lanza, M., & Castegna, A. (2022) · Molecules · doi:10.3390/molecules27030951 · Cited by 29

Potential neuroprotective role of astroglial exosomes against smoking-induced oxidative stress and HIV-1 replication in the central nervous system

Ranjit, S., Patters, B. J., Gerth, K. A., Haque, S., Choudhary, S., & Kumar, S. (2018) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2018.1501473 · Cited by 27

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles

Santos, T., Ferreira, R., Quartin, E., Boto, C., Saraiva, C., Bragança, J., Peça, J., Rodrigues, C., Ferreira, L., & Bernardino, L. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.06.044 · Cited by 26

Autophagy and Redox Homeostasis in Parkinson’s: A Crucial Balancing Act

Jiménez-Moreno, N., & Lane, J. D. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/8865611 · Cited by 26

Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally

Blossom, S. J., Cooney, C. A., Melnyk, S. B., Rau, J. L., Swearingen, C. J., & Wessinger, W. D. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.03.025 · Cited by 26

Astrocytes: inexplicable cells in neurodegeneration

Singh, S., & Joshi, N. (2016) · International Journal of Neuroscience · doi:10.3109/00207454.2016.1173692 · Cited by 26

Neuroprotective Mechanism of Hypoxic Post-conditioning Involves HIF1-Associated Regulation of the Pentose Phosphate Pathway in Rat Brain

Vetrovoy, O. V., Sarieva, K., Galkina, O., Eschenko, N., Lyanguzov, A. Y., Gluschenko, T. S., Tyulkova, E. I., & Rybnikova, E. A. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2681-x · Cited by 26

Glutathione and γ-Glutamylcysteine in Hydrogen Peroxide Detoxification

Quintana–Cabrera, R., & Bolaños, J. P. (2013) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-405882-8.00007-6 · Cited by 27

Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders

Almikhlafi, M. A., Karami, M. M., Jana, A., Alqurashi, T. M. A., Majrashi, M., Alghamdi, B. S. A., & Ashraf, G. M. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220830112408 · Cited by 26

Protective and Antioxidant Effects of a Chalconoid fromPulicaria incisaon Brain Astrocytes

Elmann, A., Telerman, A., Erlank, H., Mordechay, S., Rindner, M., Ofir, R., & Kashman, Y. (2013) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2013/694398 · Cited by 25

Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes

Pehar, M., Ball, L. E., Sharma, D. R., Harlan, B. A., Comte‐Walters, S., Neely, B. A., & Vargas, M. R. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m115.049288 · Cited by 26

Pulsed Electromagnetic Fields Stimulate HIF-1α-Independent VEGF Release in 1321N1 Human Astrocytes Protecting Neuron-like SH-SY5Y Cells from Oxygen-Glucose Deprivation

Vincenzi, F., Pasquini, S., Setti, S., Salati, S., Cadossi, R., Borea, P. A., & Varani, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218053 · Cited by 24

Cell type and sex specific mitochondrial phenotypes in iPSC derived models of Alzheimer’s disease

Flannagan, K., Stopperan, J. A., Hauger, B. M., Troutwine, B., Lysaker, C. R., Strope, T. A., Csikós, V., Gilmore, C. A., Swerdlow, N., Draper, J. M., et al. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1201015 · Cited by 24

13C metabolic flux analysis in neurons utilizing a model that accounts for hexose phosphate recycling within the pentose phosphate pathway

Gebril, H. M., Avula, B., Wang, Y., Khan, I. A., & Jekabsons, M. B. (2015) · Neurochemistry International · doi:10.1016/j.neuint.2015.12.008 · Cited by 24

Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro

Báez-Jurado, E., Hidalgo‐Lanussa, O., Guio-Vega, G. P., Ashraf, G. M., Echeverría, V., Aliev, G., & Barreto, G. E. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0771-4 · Cited by 25

Heat-induced longevity in budding yeast requires respiratory metabolism and glutathione recycling

Musa, M., Perić, M., Dib, P. B., Sobočanec, S., Šarić, A., Lovrić, A., Rudan, M., Nikolić, A., Milošević, I., Vlahoviček, K., et al. (2018) · Aging · doi:10.18632/aging.101560 · Cited by 23

Potential Novel Therapies for Neurodevelopmental Diseases Targeting Oxidative Stress

Curpăn, A.-Ș., Luca, A.-C., & Ciobica, A. S. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6640206 · Cited by 24

Refocusing the Brain: New Approaches in Neuroprotection Against Ischemic Injury

Rodriguez, C., Agulla, J., & Delgado‐Esteban, M. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03016-z · Cited by 21

MRI spectroscopic and tractography studies indicate consequences of long-term ketogenic diet

Gzieło, K., Janeczko, K. J., Węglarz, W. P., Jasiński, K., Kłodowski, K., & Setkowicz, Z. (2020) · Brain Structure and Function · doi:10.1007/s00429-020-02111-9 · Cited by 22

S-Glutathionylation and Redox Protein Signaling in Drug Addiction

Womersley, J. S., & Uys, J. D. K. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.10.001 · Cited by 21

Transcriptional regulators of redox balance and other homeostatic processes with the potential to alter neurodegenerative disease trajectory

Burnside, S. W., & Hardingham, G. E. (2017) · Biochemical Society Transactions · doi:10.1042/bst20170013 · Cited by 20

Protection of the Crayfish Mechanoreceptor Neuron and Glial Cells from Photooxidative Injury by Modulators of Diverse Signal Transduction Pathways

Uzdensky, A. B., Berezhnaya, E. V., Khaitin, A. M., Kovaleva, V. D., Komandirov, M. A., Neginskaya, M. A., Rudkovskii, M. V., & Sharifulina, S. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9237-8 · Cited by 21

Preferential Heme Oxygenase-1 Activation in Striatal Astrocytes Antagonizes Dopaminergic Neuron Degeneration in MPTP-Intoxicated Mice

Xu, X., Song, N., Wang, R., Jiang, H. F., & Xie, J. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9437-2 · Cited by 20

Time-Course Evaluation of Brain Regional Mitochondrial Bioenergetics in a Pre-Clinical Model of Severe Penetrating Traumatic Brain Injury

Pandya, J. D., Leung, L. Y., Hwang, H. M., Yang, X., Deng‐Bryant, Y., & Shear, D. A. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2020.7379 · Cited by 19

Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells

Şahin, B., & Ergül, M. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-00948-z · Cited by 19

4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson’s Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation

Tiwari, S., Gupta, P., Singh, A., Chaturvedi, S., Wahajuddin, M., Mishra, A., & Singh, S. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03691-0 · Cited by 19

Insight into a neuron's preferential susceptibility to oxidative stress

Bell, K. F. S. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130245 · Cited by 19

Nrf2 is expressed more extensively in neurons than in astrocytes following an acute epileptic seizure in rats

Sandouka, S., Saadi, A., Taiwo, R. O., Singh, P. K., & Shekh‐Ahmad, T. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15786 · Cited by 18

Activation of Nrf2 to Optimise Immune Responses to Intracerebral Haemorrhage

Loan, J. J., Salman, R. A., McColl, B. W., & Hardingham, G. E. (2022) · Biomolecules · doi:10.3390/biom12101438 · Cited by 17

miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4

Liu, Y., Gu, H., Huang, T., Wei, X., Ma, W., Liu, D., He, Y., Luo, W., Huang, J., Zhao, D., et al. (2020) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13383 · Cited by 17

Ultra-Endurance Associated With Moderate Exercise in Rats Induces Cerebellar Oxidative Stress and Impairs Reactive GFAP Isoform Profile

de Souza, R. F., Augusto, R. L., de Moraes, S. R. A., de Souza, F. B., Gonçalves, L. V. D. P., Pereira, D. D., Moreno, G. M. M., de Souza, F. M. A., & Andrade-da-Costa, B. L. D. S. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00157 · Cited by 16

Ebselen alters cellular oxidative status and induces endoplasmic reticulum stress in rat hippocampal astrocytes

Santofimia‐Castaño, P., Izquierdo-Álvarez, A., de la Casa‐Resino, I., Martı́nez-Ruiz, A., Pérez‐López, M., Portilla-Cuenca, J. C., Salido, G. M., & González, A. (2016) · Toxicology · doi:10.1016/j.tox.2016.06.002 · Cited by 17

New Implications for the Melanocortin System in Alcohol Drinking Behavior in Adolescents: The Glial Dysfunction Hypothesis

Orellana, J. A., Cerpa, W. F., Carvajal, F., Lerma-Cabrera, J. M., Karahanian, E., Osorio‐Fuentealba, C., & Quintanilla, R. A. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00090 · Cited by 17

Neuronal Activity and Its Role in Controlling Antioxidant Genes

Qiu, J., Dando, O., Febery, J. A., Fowler, J. H., Chandran, S., & Hardingham, G. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21061933 · Cited by 17

Cross-Talk Between Neurons and Astrocytes in Response to Bilirubin: Adverse Secondary Impacts

Falcão, A. S., Silva, R. F. M., Vaz, A. R., Gomes, C., Fernandes, A. M. A., Barateiro, A. P., Tiribelli, C., & Brites, D. M. T. O. (2013) · Neurotoxicity Research · doi:10.1007/s12640-013-9427-y · Cited by 17

Dynamic cell type‐specific expression of Nrf2 after traumatic brain injury in mice

Dong, W., Sun, Y., Cheng, H., Yang, B., Wang, L., Jiang, Z., Li, B., Wen, S., Guo, X., Guan, D.-W., et al. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14399 · Cited by 16

Total flavones of Dracocephalum moldavica L. protect astrocytes against H2O2-induced apoptosis through a mitochondria-dependent pathway

Zheng, R., Du, Y.-W., Zeng, C., Wang, H.-F., Xing, J., & Xu, M. (2020) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-020-2846-4 · Cited by 16

Neuroinflammation and demyelination from the point of nitrosative stress as a new target for neuroprotection

Ljubisavljević, S., & Stojanović, I. R. (2014) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0060 · Cited by 19

Updates to a 13 C metabolic flux analysis model for evaluating energy metabolism in cultured cerebellar granule neurons from neonatal rats

Jekabsons, M. B., Gebril, H. M., Wang, Y., Avula, B., & Khan, I. A. (2017) · Neurochemistry International · doi:10.1016/j.neuint.2017.03.020 · Cited by 16

3,5,4′-Trihydroxy-6,7,3′-trimethoxyflavone protects astrocytes against oxidative stress via interference with cell signaling and by reducing the levels of intracellular reactive oxygen species

Elmann, A., Telerman, A., Mordechay, S., Erlank, H., Rindner, M., Ofir, R., & Kashman, Y. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.09.003 · Cited by 15

2, 2′‐ and 4, 4′‐Cyanines are transporter‐independentin vitrodopaminergic toxins with the specificity and mechanism of toxicity similar to MPP +

Kadigamuwa, C. C., Le, V. Q., & Wimalasena, K. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13201 · Cited by 15

Purinergic receptor stimulation decreases ischemic brain damage by energizing astrocyte mitochondria.

Sayre, N. L., Chen, Y.-N., Sifuentes, M. M., Stoveken, B., & Lechleiter, J. D. (2014) · Advances in neurobiology · doi:10.1007/978-3-319-08894-5_7 · Cited by 15

The cellular basis of fetal endoplasmic reticulum stress and oxidative stress in drug-induced neurodevelopmental deficits

Tsai, S.-Y. A., Bendriem, R. M., & Lee, C.-T. D. (2018) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.100145 · Cited by 15

Agmatine protection against chlorpromazine-induced forebrain cortex injury in rats

Dejanović, B., Stevanović, I. D., Ninković, M., Stojanović, I. R., Lavrnja, I. C., Radičević, T., & Pavlović, M. (2016) · Journal of Veterinary Science · doi:10.4142/jvs.2016.17.1.53 · Cited by 14

Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons

Logica, T., Rivière, S., Holubiec, M., Castilla, R., Barreto, G., & Capani, F. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00116 · Cited by 11

Antioxidants and Neuron-Astrocyte Interplay in Brain Physiology: Melatonin, a Neighbor to Rely on

González, A. (2020) · Neurochemical Research · doi:10.1007/s11064-020-02972-w · Cited by 14

Antioxidants as a preventive therapeutic option for age related neurodegenerative diseases

(2015) · Therapeutic Targets for Neurological Diseases · doi:10.14800/ttnd.592 · Cited by 13

Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.

Yang, J., & Liu, C. Q. (2000) · PubMed · Cited by 13

Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats

Khan, G., Alam, M. F., Alshahrani, S., Almoshari, Y., Jali, A. M., Alqahtani, S., Khalid, M., Ullah, S. N. M. N., & Anwer, T. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13050750 · Cited by 12

Prenatal exposure to cigarette smoke enhances oxidative stress in astrocytes of neonatal rat

Hamdi, Y., Madfai, H., Belhareth, R., Mokni, M., Masmoudi‐Kouki, O., & Amri, M. (2016) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2016.1156205 · Cited by 12

Do glial cells play an anti-oxidative role in Huntington's disease?

Gao, Y., Chu, S., Li, J.-P., Zuo, W., Wen, Z.-L., He, W., Yan, J., & Chen, N. H. (2014) · Free Radical Research · doi:10.3109/10715762.2014.936432 · Cited by 12

Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality

Singh, S., Goo, J.-I., Noh, H., Lee, S. J., Kim, M. W., Park, H., Jalani, H. B., Lee, K., Kim, C., Kim, W.-K., et al. (2017) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2016.12.052 · Cited by 12

Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice

Wulaer, B., Hada, K., Sobue, A., Itoh, N., Nabeshima, T., Nagai, T., & Yamada, K. (2020) · Molecular Brain · doi:10.1186/s13041-020-00710-5 · Cited by 12

Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Piquet, J., Toussay, X., Hepp, R., Lerchundi, R., Douce, J. L., Faivre, É., Guiot, E., Bonvento, G., & Cauli, B. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00216 · Cited by 13

The consequences of neurodegenerative disease on neuron-astrocyte metabolic and redox interactions

Jiwaji, Z., & Hardingham, G. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106255 · Cited by 11

Spinal Cord Injury Model Mitochondria Connect Altered Function with Defects of Mitochondrion Morphology: an Ultrastructural Study

Hassanzadeh, S., Sabetvand, M., Sardar, R., Aryanpour, R., & Namjoo, Z. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03710-3 · Cited by 11

Effect of the Combination of Different Therapies on Oxidative Stress in the Experimental Model of Multiple Sclerosis

Escribano, B. M., Muñoz-Jurado, A., Luque, E., Galván, A., LaTorre, M., Caballero‐Villarraso, J., Giraldo, A. I., Agüera, E., & Túnez, I. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.08.005 · Cited by 10

Understanding glaucoma as astrocyte-driven neurodegeneration in the optic nerve head: an integrative clinicopathological perspective

Lee, E. J., Park, D. Y., Han, J. C., & Kee, C. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101379 · Cited by 13

Single is not combined: The role of Co and Ni bioavailability on toxicity mechanisms in liver and brain cells

Thiel, A., Michaelis, V., Restle, M., Figge, S., Simon, M. C., Schwerdtle, T., & Bornhorst, J. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.142091 · Cited by 10

The effects of the fungicides fenhexamid and myclobutanil on SH-SY5Y and U-251 MG human cell lines

Nagel, D. A., Hill, E. J., O’Neil, J. D., Mireur, A., & Coleman, M. D. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.09.005 · Cited by 10

Pulicaria incisa infusion attenuates inflammatory responses of brain microglial cells

Elmann, A., Beit‐Yannai, E., Telerman, A., Ofir, R., Mordechay, S., Erlank, H., & Borochov‐Neori, H. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.05.012 · Cited by 10

Nutrient-Deprived Retinal Progenitors Proliferate in Response to Hypoxia: Interaction of the HIF-1 and mTOR Pathway

Khaliullina, H., Love, N. K., & Harris, W. A. (2016) · Journal of Developmental Biology · doi:10.3390/jdb4020017 · Cited by 8

The NADPH Link between the Renin Angiotensin System and the Antioxidant Mechanisms in Dopaminergic Neurons

Franco, R., Serrano‐Marín, J., Navarro, G., & Rivas‐Santisteban, R. (2023) · Antioxidants · doi:10.3390/antiox12101869 · Cited by 8

Achillolide A Protects Astrocytes against Oxidative Stress by Reducing Intracellular Reactive Oxygen Species and Interfering with Cell Signaling

Elmann, A., Telerman, A., Erlank, H., Ofir, R., Kashman, Y., & Beit‐Yannai, E. (2016) · Molecules · doi:10.3390/molecules21030301 · Cited by 8

Probing Oxidant Effects on Superoxide Dismutase 1 Oligomeric States in Live Cells Using Single-Molecule Fluorescence Anisotropy

Chen, H., & Chen, T. (2023) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.3c00002 · Cited by 7

Targeting ferroptosis in the neurovascular unit: A promising approach for treating diabetic cognitive impairment

Zhang, W., Yan, Y., Yi, C., Jiang, X., Guo, L., Huang, S., Xia, T., Huang, F., Jiao, Y., Li, H., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113146 · Cited by 6

4HNE Protein Adducts in Autistic Spectrum Disorders: Rett Syndrome and Autism

Valacchi, G., Pecorelli, A., Signorini, C., Leoncini, S., Ciccoli, L., Felice, C. D., & Hayek, J. (2013) · Springer eBooks · doi:10.1007/978-1-4614-4788-7_199 · Cited by 6

Neuron–Glia Crosstalk in the Regulation of Astrocytic Antioxidative Mechanisms Following CNS Injury

Zakrzewski, P. K., & Boczek, T. (2025) · Antioxidants · doi:10.3390/antiox14121415 · Cited by 10

Metabolomic profiling reveals a differential role for hippocampal glutathione reductase in infantile memory formation

Bessières, B., Cruz, E., & Alberini, C. M. (2021) · eLife · doi:10.7554/elife.68590 · Cited by 5

Severe spinal cord hypoplasia due to a novel ATAD3A compound heterozygous deletion

Ebihara, T., Nagatomo, T., Sugiyama, Y., Tsuruoka, T., Osone, Y., Shimura, M., Tajika, M., Ichimoto, K., Naruke, Y., Akiyama, N., et al. (2022) · Molecular Genetics and Metabolism Reports · doi:10.1016/j.ymgmr.2022.100912 · Cited by 5

The Effect of Severe Hypoxia on HIF1- and Nrf2-Mediated Mechanisms of Antioxidant Defense in the Rat Neocortex

Sarieva, K., Lyanguzov, A. Y., Galkina, O. V., & Vetrovoy, O. V. (2019) · Neurochemical Journal · doi:10.1134/s1819712419020107 · Cited by 5

PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3)

Novellasdemunt, L., Navarro‐Sabaté, À., Manzano, À., Rodríguez‐García, A., & Bartrons, R. (2013) · Atlas of Genetics and Cytogenetics in Oncology and Haematology · doi:10.4267/2042/51425 · Cited by 5

High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis

Céléreau, E., Lucchetti, F., Alemán‐Gómez, Y., Dwir, D., Cleusix, M., Ledoux, J., Jenni, R., Conchon, C., Cuadra, M. B., Schilliger, Z., et al. (2026) · Imaging Neuroscience · doi:10.1162/imag.a.1276 · Cited by 4

Animal Models and Experimental Research in Medicine

Karapehlivan, M., Gelen, V., & Kükürt, A. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.100993 · Cited by 4

Investigating the Effect of Cigarette Smoking on Serum Uric Acid Levels in Multiple Sclerosis Patients: A Cross Sectional Study

Alrouji, M., Manouchehrinia, A., Aram, J., Alotaibi, A., Alhajlah, S. H., Almuhanna, Y., AlOmeir, O., Shamsi, A., Gran, B., & Constantinescu, C. S. (2023) · Brain Sciences · doi:10.3390/brainsci13050800 · Cited by 4

PrP (122–139) is a covert mitochondrial targeting signal of prion protein and it specifically triggers the perinuclear clustering of mitochondria in neuronal culture cells

Shimizu, T., Kozuka, Y., Kusano, M., Nagane, M., Yamashita, T., & Hachiya, N. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.01.099 · Cited by 4

Coenzyme Q10 Modulates Apoptotic Effects of Chronic Administration of Methadone on NMRI Mouse Hippocampus.

Vaselbehagh, M., Sadegh, M., Karami, H., Babaie, S., & Sakhaie, M. H. (2021) · PubMed Central · doi:10.22074/cellj.2021.7384 · Cited by 4

An ex vivo Approach to Assess Mitochondrial ROS by Flow Cytometry in AAV-tagged Astrocytes in Adult Mice

Vicente‐Gutiérrez, C., & Bolaños, J. P. (2020) · BIO-PROTOCOL · doi:10.21769/bioprotoc.3550 · Cited by 4

Comparative Analysis of the Effects of Maternal Hypoxia and Placental Ischemia on HIF1-Dependent Metabolism and the Glucocorticoid System in the Embryonic and Newborn Rat Brain

Vetrovoy, O. V., Potapova, S., Stratilov, V. A., & Tyulkova, E. I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413342 · Cited by 3

Transcription Factor HIF1 Negatively Regulates the Content of Glucose-6-Phosphate Dehydrogenase in HEK293T Cells

Vetrovoy, O. V., Nimiritsky, P., Tyulkova, E. I., & Rybnikova, E. A. (2021) · Cell and Tissue Biology · doi:10.1134/s1990519x21020127 · Cited by 3

Expression of nuclear factor-erythroid 2-related factor 2 in rat brain following the administration of kainic acid and pentylenetetrazole

Ruíz-Díaz, A., Manjarrez-Marmolejo, J., Nava-Ruíz, C., Zaga‐Clavellina, V., Flores‐Espinosa, P., Dı́az-Ruiz, A., Yescas, P., & Méndez‐Armenta, M. (2019) · Neuroreport · doi:10.1097/wnr.0000000000001207 · Cited by 2

Propofol Protects the Blood-Brain Barrier After Traumatic Brain Injury by Stabilizing the Extracellular Matrix via Prrx1: From Neuroglioma to Neurotrauma

Zhang, L., Wu, C., Liu, T., Tian, Y., Wang, D., Wang, B., & Yin, Y. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04202-z · Cited by 2

Neuron-glia metabolic coupling: Role in plasticity and neuroprotection

Magistretti, P. J. (2017) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2017.08.107 · Cited by 3

The consequences of neurodegenerative disease on neuron-astrocyte metabolic and redox interactions

Jiwaji, Z., & Hardingham, G. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106255 · Cited by 11

Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation

Almeida, Á., Jiménez-Blasco, D., & Bolaños, J. P. (2023) · Essays in Biochemistry · doi:10.1042/ebc20220075 · Cited by 118

Multifunctional role of astrocytes as gatekeepers of neuronal energy supply

Stobart, J. L., & Anderson, C. M. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00038 · Cited by 280

Astrocyte-neuron metabolic cooperation shapes brain activity

Bonvento, G., & Bolaños, J. P. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.07.006 · Cited by 580