Antioxidant and bioenergetic coupling between neurons and astrocytes

How mitochondria produce reactive oxygen species

Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196

Ischemic Cell Death in Brain Neurons

Lipton, P. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1431 · Cited by 3,043

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Pellerin, L., & Magistretti, P. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.22.10625 · Cited by 2,927

Nitric oxide synthases in mammals

Knowles, R. G., & Moncada, S. (1994) · Biochemical Journal · doi:10.1042/bj2980249 · Cited by 2,752

Oxidative stress and neurodegeneration: where are we now?

Halliwell, B. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03907.x · Cited by 2,614

Molecular dissection of reactive astrogliosis and glial scar formation

Sofroniew, M. V. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.08.002 · Cited by 2,594

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

Garthwaite, J., Charles, S. L., & Chess‐Williams, R. (1988) · Nature · doi:10.1038/336385a0 · Cited by 2,540

Glial and neuronal control of brain blood flow

Attwell, D., Buchan, A. M., Charpak, S., Lauritzen, M., MacVicar, B. A., & Newman, E. A. (2010) · Nature · doi:10.1038/nature09613 · Cited by 2,511

A Systems Biology Approach Towards a Comprehensive Understanding of Ferroptosis

Arbatskiy, M. S., Balandin, D. E., Akberdin, I. R., & Churov, A. V. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111782 · Cited by 4

Protective effect of apelin-13 in lens epithelial cells via inhibiting oxidative stress-induced apoptosis

Li, X., Gu, C., Hu, Q., Wang, L., Zhang, Y., & Yu, L. (2024) · BMC Ophthalmology · doi:10.1186/s12886-024-03746-6 · Cited by 2

Common Features of Oxidative Stress and Metabolic Impairments in Human Erythrocytes and Nucleated Cells

Ghashghaeinia, M., Wieder, T., & Duszenko, M. (2014) · CRC Press eBooks · doi:10.1201/b16653-22 · Cited by 2

Influence of Prenatal Stress on the Activity of Antioxidant Enzymes in the Subcellular Fractions of the Neurons and Neuroglia of the Rat Neocortex

Vyushina, A. V., Притворова, А. В., Semenova, O. G., & Ordyan, N. E. (2020) · Neurochemical Journal · doi:10.1134/s1819712420020130 · Cited by 2

Neurodegenerative features of damage to Deiters neurons in the lateral vestibular nucleus of mice after vestibular stimulation

Mikheeva, I. B., Zhuikova, N. S., Chernomorets, I. Y., Pavlik, L. L., & Arkhipov, V. I. (2025) · Neuroscience Letters · doi:10.1016/j.neulet.2025.138363 · Cited by 1

Renin-angiotensin system blockade attenuates brain mitochondrial dysfunction, oxidative stress, and neuroinflammation associated with hypertension, metabolic disorders, and aging

Menéndez, S. G., Inserra, F., de Cavanagh, E. M. V., Ferder, L., & Manucha, W. A. (2026) · World Journal of Experimental Medicine · doi:10.5493/wjem.v16.i1.113259 · Cited by 1

Changes in the expression of astroglial and microglial markers in the hippocampus of rats adapted to chronic stress and the effects of panthenol

Тишкина, А. О., Novikova, M. R., Stepanichev, M. Y., Levshina, I. P., Pasikova, N. V., Лазарева, Н. А., Мойсеенок, А. Г., & Gulyaeva, N. V. (2013) · Neurochemical Journal · doi:10.1134/s1819712413020074 · Cited by 1

Hidrojen Peroksit ile İndüklenen C6 Hücrelerinde Oksidatif Stres Kaynaklı Apoptosis ve İnflamatuar Artışına Karşı Astaksantinin Koruyucu Etkisi

Joha, Z., & Taşkıran, A. Ş. (2023) · Turkish Journal of Agriculture - Food Science and Technology · doi:10.24925/turjaf.v11i9.1686-1692.6281 · Cited by 1

The effect of phencyclidine-mediated blockade of NMDA receptors in the early postnatal period on glutathione and sulfur amino acid levels in the rat brain as a potential causative factor of schizophrenia-like behavior in adulthood

Lorenc‐Koci, E., Górny, M., Chwatko, G., Kamińska, K., Iciek, M., & Rogóż, Z. (2024) · Pharmacological Reports · doi:10.1007/s43440-024-00607-3 · Cited by 1

Neuroglia in stroke

Verkhratsky, A., & Sofroniew, M. V. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19102-2.00009-0 · Cited by 1

Oxidative Stress, Redox Homeostasis and NF-κB Signaling in Neurodegeneration

Anandhan, A., Hernández-Franco, P., & Franco, R. (2015) · ACS symposium series · doi:10.1021/bk-2015-1200.ch003 · Cited by 1

Applied neuropathophysiology and neuropharmacology

Muralidharan, R., & Kofke, W. A. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780198739555.003.0002 · Cited by 1

Astrocytes and microglia in Parkinson's disease and animal models

Kuter, K. Z. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815950-7.00006-0 · Cited by 1

Rising of intracellular NAD+ level and oppositely directed changes in CD38 expression in hippocampal cells in experimental Alzheimer’s disease

Асатовна, С. А., Gorina, Y. V., Хилажева, Е. Д., Kharitonova, E. V., & Salmina, A. B. (2021) · Сибирский научный медицинский журнал · doi:10.18699/ssmj20210505 · Cited by 1

Exposición ocupacional al formaldehído y sus efectos sobre el sistema nervioso central

Sánchez-Zavaleta, V., Moreno, A. M., Diaz, J. A. M., Aranda-Abreu, G. E., Herrera‐Covarrubias, D., Coria‐Ávila, G. A., Suárez-Medellín, J. M., Manzo, J. G., & Aguilar, M. E. H. (2018) · eNeurobiología · doi:10.25009/eb.v9i22.2538 · Cited by 1

The Role of Oxidative Stress on Neural TRPC3, TRPC5, TRPC6 Expression and/or Function and Relevance to Bipolar Disorder

Tong, S. Y. C. (2012) · TSpace (University of Toronto) · Cited by 1

Mecanismos de regulación de la glucolisis en neuronas y su función en supervivencia celular

Rodríguez, P. R. (2013) · Gredos (University of Salamanca) · doi:10.14201/gredos.123044

Alterations of Thalamostriatal and Corticostriatal Projections in Mouse Models of Huntington’s Disease

Parievsky, A. (2015) · eScholarship (California Digital Library)

Análise da participação das células neuronais e não-neuronais na Esclerose Lateral Amiotrófica em camundongos transgênicos para SOD1 humana utilizando técnicas de microdissecção a laser e PCR em tempo real

de Oliveira, G. P. (2014) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2014.tde-06062014-101803

Molecular Mechanisms of Astrocyte Vesicle Fusion at Synaptic Interfaces

Wolfes, A. C. (2015) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-5372

Astrocytes: Puzzle in Neurodegeneration

Singh, S. (2015) · Research and reviews : journal of pharmaceutics and nanotechnology

Glucose-6-phosphate dehydrogenase deficiency: A possible risk factor for neurodegeneration associated with aging and amphetamine use

Loniewska, M. M. (2013) · TSpace (University of Toronto)

Oxidative Stress and Redox Signalling in the Parkinson’s Disease Brain

Hernández-Franco, P., Anandhan, A., Foguth, R. M., & Franco, R. (2017) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622888-00027

Efeitos da administração aguda de glicose após atividade física sobre o comportamento relacionado à ansiedade, memória e neuroplasticidade

Shimizu, W. A. L. (2015) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.47.2015.tde-08052015-115148

Neuroprotective Effects of Sulforaphane on Oxygen/Glucose Deprived Neurons and Astrocytes

Yoon, J. (2016) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r35717t2t

Contribution to the biochemical characterization of astrocytes expressing a mitochondrial-tagged form of catalase

Bonora, N. (2018) · Gredos (University of Salamanca) · doi:10.14201/gredos.137569

Transcriptional and functional consequences of neuron-astrocyte interactions

Jiwaji, Z. (2019) · ERA

The Impact of Impaired Cyclooxygenase-2 Activity on Mouse Brain Development: A Focus on Sex Differences

Sterling, K. (2020) · York University Digital Library (York University)

Astrocyte specific proteins content in the different parts of the rat and mongolian gerbil brain during ontogenesis

Kovalchuk, Y. P., Shiyntum, H. N., & Ушакова, Г. А. (2021) · The Ukrainian Biochemical Journal · doi:10.15407/ubj93.03.013

The Environmental Contribution to Redox Dyshomeostasis in Parkinson’s Disease

Garza-Lombó, C., & Franco, R. (2022) · Molecular and integrative toxicology · doi:10.1007/978-3-030-87451-3_4

TPNA10168, an Nrf-2 activator, stimulates glutathione production by inducing system Xc-, and g-glutamate cysteine ligase subunits in cultured mouse astrocytes.Preprint

Koyama, Y., Terada, N., Nakamura, H., Ito, K., Kume, T., & Izumi, Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1567238/v1

Desarrollo de un modelo experimental de estrés oxidativo in vivo

Fernández, S. F. (2013) · Gredos (University of Salamanca) · doi:10.14201/gredos.122960

Mitochondrial OxPhos: the integrator of the cellular metabolic status

Lechuga‐Vieco, A. V. (2018) · doi:10.4321/repisalud.6736

Melatonin protect PC12 cells from hydrogen peroxide-induced damage via the Nrf2/HO-1 signaling pathwayPreprint

Zhang, Y., Guo, X., Cheng, X., Hu, X., Kang, J., Lin, A., Kang, X., & He, X. (2022) · Research Square · doi:10.21203/rs.3.rs-1668785/v1

Potencial efecto del medio condicionado de células madre mesenquimales derivadas de tejido adiposo sobre astrocitos humanos en un modelo in vitro de scratch y privación de glucosa

Jurado, E. M. B. (2020) · Repositorio Institucional (Pontificia Universidad Javeriana) · doi:10.11144/javeriana.10554.41814

The Effect of Prenatal Stress on Glutathione-Associated Antioxidant Enzyme Activity in Subcellular Fractions of Neocortical Neurons and Neuroglia of Rats during the Period of Intensive Myelination

Vyushina, A. V., Притворова, А. В., Semenova, O. G., & Ordyan, N. E. (2022) · Neurochemical Journal · doi:10.1134/s1819712422030138

Spatio-Temporal and Cell Type-Specific Expression of Nrf2 Following an Acute Epileptic Seizure in RatsPreprint

Sandouka, S., Saadi, A., Taiwo, R. O., Singh, P. K., & Shekh‐Ahmad, T. (2022) · Preprints.org · doi:10.20944/preprints202210.0300.v1

Retinal Disorders in Humans and Experimental ALS Models

Rojas, P., Ramirez, A. I., de Hoz, R., Cadena, M., Salobrar‐García, E., López‐Cuenca, I., Fernández‐Albarral, J. A., Sánchez-Puebla, L., Matamoros, J. A., Salazar, J. J., et al. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.107052

Oxidative stress accompanies HIF1-dependent impairment of glucose metabolism in the hippocampus of adult rats survived prenatal severe hypoxiaPreprint

Vetrovoy, O. V., Stratilov, V. A., Potapova, S., & Tyulkova, E. I. (2023) · Research Square · doi:10.21203/rs.3.rs-3248640/v1

CDH1 regula la mielinización durante el desarrollo del Sistema Nervioso Central

Huguet, S. G. (2023) · Gredos (University of Salamanca) · doi:10.14201/gredos.153236

Sobrecarga de cobre y enfermedad de Alzheimer, búsqueda de posibles blancos terapéuticos

Zubillaga, M. (2023) · El Servicio de Difusión de la Creación Intelectual (National University of La Plata) · doi:10.35537/10915/165188

Additional file 1 of Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathway

Lu, L., Wang, H., Liu, X., Tan, L., Qiao, X., Ni, J., Sun, Y., Liang, J., Hou, Y., & Dou, H. (2021) · Figshare · doi:10.6084/m9.figshare.16807867

Additional file 1 of Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy

Sandouka, S., Saadi, A., Singh, P. K., Taiwo, R. O., & Shekh‐Ahmad, T. (2023) · Figshare · doi:10.6084/m9.figshare.22607986

Tabac et grossesse

Belhareth, R. (2016) · theses.fr (ABES) · doi:10.70675/6d8344f3z09b5z40d0z8e1czb7f76f2bd888

Rôle des connexines 43 astrocytaires : une étude fonctionnelle dans un modèle murin de dépression basé sur le stress chronique

Portal, B. (2019) · theses.fr (ABES) · doi:10.70675/d20c8f2azc2f7z48a8z9545z80352abaf664

Pentose Phosphate Pathway Is Critical for Providing Energy by Bypassing 6-Phosphofructo-1-Kinase (PFK1) During Increased Neuronal Activity

Kristián, T., Waddell, J., & MCKENNA, M. C. (2026) · Metabolites · doi:10.3390/metabo16050321

Feasibility Study of Intratumoral NRF2 Expression as a Predictive Biomarker for the Effectiveness of Immunotherapy in Patients with Non-Small Cell Lung Cancer Treated with PD-1 Inhibitor

Jin, Y., Inoue, Y., Shimada, H., Hara, T., Yamashita, S., Yamamoto, M., & Matsubara, O. (2026) · Cancers · doi:10.3390/cancers18142202

Neuron-glia metabolic coupling: Role in plasticity and neuroprotection

Magistretti, P. J. (2017) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2017.08.107 · Cited by 3

The consequences of neurodegenerative disease on neuron-astrocyte metabolic and redox interactions

Jiwaji, Z., & Hardingham, G. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106255 · Cited by 11

Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation

Almeida, Á., Jiménez-Blasco, D., & Bolaños, J. P. (2023) · Essays in Biochemistry · doi:10.1042/ebc20220075 · Cited by 118

Multifunctional role of astrocytes as gatekeepers of neuronal energy supply

Stobart, J. L., & Anderson, C. M. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00038 · Cited by 280

Astrocyte-neuron metabolic cooperation shapes brain activity

Bonvento, G., & Bolaños, J. P. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.07.006 · Cited by 580