Inositol pyrophosphates: between signalling and metabolism

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The Nudix hydrolase superfamily

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Initiating Cellular Stress Responses

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Growth control and ribosome biogenesis

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Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

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Phosphorylation of Proteins by Inositol Pyrophosphates

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Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates

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A Conserved Family of Enzymes That Phosphorylate Inositol Hexakisphosphate

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Chemotaxis in the Absence of PIP3 Gradients

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Common mechanisms of PIKK regulation

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Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

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Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

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Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event

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Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells

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Assessing the omnipotence of inositol hexakisphosphate

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Inositol Pyrophosphates Mediate Chemotaxis in Dictyostelium via Pleckstrin Homology Domain-PtdIns(3,4,5)P3 Interactions

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The Inositol Hexakisphosphate Kinase Family

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Stepwise phosphorylation of myo-inositol leading to myo-inositol hexakisphosphate in Dictyostelium

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Inositol pyrophosphates: metabolism and signaling

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Inositol pyrophosphates regulate endocytic trafficking

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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

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Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor.

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Regulation of nuclear processes by inositol polyphosphates

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A novel context for the ‘MutT’ module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

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Common Genetic Variants Associate with Serum Phosphorus Concentration

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Inositol Hexakisphosphate Kinase 2 Mediates Growth Suppressive and Apoptotic Effects of Interferon-β in Ovarian Carcinoma Cells

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Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases

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Identification and Characterization of a Novel Inositol Hexakisphosphate Kinase

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Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate

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Inositol Diphosphate Signaling Regulates Telomere Length

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Diphosphoinositol Polyphosphates: Metabolic Messengers?

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Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

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The Diadenosine Hexaphosphate Hydrolases fromSchizosaccharomyces pombe and Saccharomyces cerevisiae Are Homologues of the Human Diphosphoinositol Polyphosphate Phosphohydrolase

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Inositol Pyrophosphates and Their Unique Metabolic Complexity: Analysis by Gel Electrophoresis

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Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding

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Cloning and Characterization of Two Human VIP1-like Inositol Hexakisphosphate and Diphosphoinositol Pentakisphosphate Kinases

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Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release

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Mitochondrial fatty acid synthesis and respiration

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Plc1p, Arg82p, and Kcs1p, Enzymes Involved in Inositol Pyrophosphate Synthesis, Are Essential for Phosphate Regulation and Polyphosphate Accumulation in Saccharomyces cerevisiae

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Structural Analysis and Detection of Biological Inositol Pyrophosphates Reveal That the Family of VIP/Diphosphoinositol Pentakisphosphate Kinases Are 1/3-Kinases

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Purification, Sequencing, and Molecular Identification of a Mammalian PP-InsP5 Kinase That Is Activated When Cells Are Exposed to Hyperosmotic Stress

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Inositol Hexakisphosphate Kinase Products Contain Diphosphate and Triphosphate Groups

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Inositol Hexakisphosphate Kinase-2, a Physiologic Mediator of Cell Death

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HSP90 regulates cell survival via inositol hexakisphosphate kinase-2

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Characterization of a Selective Inhibitor of Inositol Hexakisphosphate Kinases

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p53-mediated apoptosis requires inositol hexakisphosphate kinase-2

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Specific interaction of IP6 with human Ku70/80, the DNA‐binding subunit of DNA‐PK

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SnapShot: Inositol Phosphates

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Discovery of Molecular and Catalytic Diversity among Human Diphosphoinositol-Polyphosphate Phosphohydrolases

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Inositol Pyrophosphates Are Required for DNA Hyperrecombination in Protein Kinase C1 Mutant Yeast

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Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells

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20 years of Ins(1,4,5)P3, and 40 years before

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Ageing and metabolism: drug discovery opportunities

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The Inositol Phosphates

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Binding of Inositol Hexakisphosphate (IP6) to Ku but Not to DNA-PKcs

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Genome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe

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PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase

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Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis

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Are inositol pyrophosphates signalling molecules?

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Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.

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Nutrient-Regulated Antisense and Intragenic RNAs Modulate a Signal Transduction Pathway in Yeast

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Synthesis and characterization of non-hydrolysable diphosphoinositol polyphosphate messengers

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Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle

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Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator Ribose 1,5-Bisphosphate

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Signaling by Higher Inositol Polyphosphates

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Inositol pyrophosphates modulate hydrogen peroxide signalling

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How inositol pyrophosphates control cellular phosphate homeostasis?

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Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma

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Signal transduction during environmental stress: InsP8 operates within highly restricted contexts

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Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

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Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain

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Inositol Polyphosphate Binding Specificity of the Jasmonate Receptor Complex

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Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates

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Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae

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Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases

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Regulation of plant biotic interactions and abiotic stress responses by inositol polyphosphates

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Prometabolites of 5‐Diphospho‐myo‐inositol Pentakisphosphate

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Chemical Pyrophosphorylation of Functionally Diverse Peptides

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Asp1 from Schizosaccharomyces pombe Binds a [2Fe-2S]2+ Cluster Which Inhibits Inositol Pyrophosphate 1-Phosphatase Activity

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Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review

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Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels

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Phosphate, inositol and polyphosphates

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Extra-phosphoric effects of super dosing phytase on growth performance of pigs is not solely due to release of myo-inositol

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Versatile signaling mechanisms of inositol pyrophosphates

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Inositol Phosphates Purification Using Titanium Dioxide Beads

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Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

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Inositol hexakisphosphate kinase-1 interacts with perilipin1 to modulate lipolysis

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A short history of inositol lipids

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IPMK: A Versatile Regulator of Nuclear Signaling Events

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Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules

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Acid stress induces differential accumulation of metabolites inEscherichia coliO26:H11

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A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae

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Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants

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Functions of inorganic polyphosphates in eukaryotic cells: a coat of many colours

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Inositol phosphates induce DAPI fluorescence shift

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5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis

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Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions

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Chemical tools for interrogating inositol pyrophosphate structure and function

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Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1

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Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function?

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Dissection of the PHO pathway in Schizosaccharomyces pombe using epistasis and the alternate repressor adenine

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Microbial inositol polyphosphate metabolic pathway as drug development target

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IP7-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery

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Role of transporters in regulating mammalian intracellular inorganic phosphate

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Lithium and fluoxetine regulate the rate of phosphoinositide synthesis in neurons: a new view of their mechanisms of action in bipolar disorder

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Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

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Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues

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Inositol polyphosphates regulate and predict yeast pseudohyphal growth phenotypes

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An Affinity Reagent for the Recognition of Pyrophosphorylated Peptides

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Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

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Effect of phytase on intestinal phytate breakdown, plasma inositol concentrations, and glucose transporter type 4 abundance in muscle membranes of weanling pigs1

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A high energy phosphate jump - From pyrophospho-inositol to pyrophospho-serine

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The emerging roles of inositol pyrophosphates in eukaryotic cell physiology

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Inositol Pyrophosphates as Versatile Metabolic Messengers

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Intimate connections: Inositol pyrophosphates at the interface of metabolic regulation and cell signaling

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Preparation of Quality Inositol Pyrophosphates

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Inositol Pyrophosphates as Mammalian Cell Signals

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