The DOI matches its Crossref record; 212 of the 212 references it cites were found in a registry or an index.
Regulation of protein function by S‐glutathiolation in response to oxidative and nitrosative stress
Abstract
Protein S‐glutathiolation, the reversible covalent addition of glutathione to cysteine residues on target proteins, is emerging as a candidate mechanism by which both changes in the intracellular redox state and the generation of reactive oxygen and nitrogen species may be transduced into a functional response. This review will provide an introduction to the concepts of oxidative and nitrosative stress and outline the molecular mechanisms of protein regulation by oxidative and nitrosative thiol‐group modifications. Special attention will be paid to recently published work supporting a role for S‐glutathiolation in stress signalling pathways and in the adaptive cellular response to oxidative and nitrosative stress. Finally, novel insights into the molecular mechanisms of S‐glutathiolation as well as methodological problems related to the interpretation of the biological relevance of this post‐translational protein modification will be discussed.
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Free radicals and antioxidants in normal physiological functions and human disease
Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., & Telser, J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.001 · Cited by 14,269
Free radicals, metals and antioxidants in oxidative stress-induced cancer
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Crosstalk of reactive oxygen species and NF-κB signaling
Morgan, M. J., & Liu, Z.-G. (2011) · Cell Research · doi:10.1038/cr.2010.178 · Cited by 3,505
The Role of Oxidative Stress in Carcinogenesis
Klaunig, J. E., & Kamendulis, L. M. (2004) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121851 · Cited by 1,533
Foyer, C. H., & Noctor, G. (2003) · Physiologia Plantarum · doi:10.1034/j.1399-3054.2003.00223.x · Cited by 1,316
Metadata
- Authors
- Klatt, P., & Lamas, S.
- Venue
- European Journal of Biochemistry
- Publisher
- Wiley
- Published
- 2000-08
- Volume
- 267
- Issue
- 16
- Pages
- 4928-4944
- ISSN
- 0014-2956 (ISSN-L)
- 1432-1033
- OpenAlex
- W1598978469
- Cited by
- 745
- References
- 212
- FWCI
- 8.67
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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