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Cited by 94Glaucoma and retinal disordersOphthalmology and Visual Health ResearchDrug-Induced Ocular Toxicity

Mydriasis and glaucoma: exploding the myth. A systematic review

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Pandit, R. J., Taylor, R.·2000·Diabetic Medicine
DOI 10.1046/j.1464-5491.2000.00368.x
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Abstract

Aims To investigate the risk of inducing acute glaucoma following mydriasis. Methods Systematic review of published research 1933-1999. Results The risk of inducing acute glaucoma following mydriasis with tropicamide alone is close to zero, no case being identified. The risk with long-acting or combined agents is between 1 in 3,380 and 1 in 20,000. The presence of chronic glaucoma constitutes no additional risk. Conclusions Mydriasis with tropicamide alone is safe even in people with chronic glaucoma. It should be advised in all patients when thorough retinal examination is indicated.

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59 of 59 references verified0 citation errors · 0 not checkable

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  • Reflexive dilation protocol introduces another step in the primary care workflow in addition to a small patient risk, requiring the operator to be comfortable performing the procedure and understand relevant contraindications, as well as accommodation for added visit time and ensuring patients have transportation means.

    “This introduces another step in the primary care workflow in addition to a small patient risk,62 requiring the operator to be comfortable performing the procedure and understand relevant contraindications, as well as accommodation for added visit time and ensuring patients have transportation means.”

    From Autonomous Artificial Intelligence in Diabetic Retinopathy Testing—Lessons Learned on Successful Health System Adoption (2026) · cites this paper as [62]

  • In a retrospective review of 241 patients, Shou et al's predictive dilation model using type 1 diabetes, smoking, age, race, sex, and hypertension achieved an area under the receiver operating characteristics curve of 0.76, with sensitivity of 77% and specificity of 68% at 50% cutoff value.

    “The model demonstrated an area under the receiver operating characteristics curve of 0.76, with sensitivity of 77% and specificity of 68% at 50% cutoff value.45”

    From Autonomous Artificial Intelligence in Diabetic Retinopathy Testing—Lessons Learned on Successful Health System Adoption (2026) · cites this paper as [45]

  • Some patient factors correlated to nondiagnostic image include type 1 diabetic mellitus, smoking, old age, and cataracts.

    “Some patient factors correlated to nondiagnostic image include type 1 diabetic mellitus, smoking, old age, and cataracts.45,49”

    From Autonomous Artificial Intelligence in Diabetic Retinopathy Testing—Lessons Learned on Successful Health System Adoption (2026) · cites this paper as [45]

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Related

Authors
Pandit, R. J., & Taylor, R.
Affiliations
Royal Victoria Infirmary (GB)
Corresponding author
Taylor, R.
ORCID
Taylor, R.
Venue
Diabetic Medicine
Publisher
Wiley
Published
2000-10
Volume
17
Issue
10
Pages
693-699
ISSN
  • 0742-3071 (ISSN-L)
  • 1464-5491
DOI
10.1046/j.1464-5491.2000.00368.x
OpenAlex
W2072138623
Cited by
94
References
59
Citations by year
2026: 2 · 2025: 3 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 7 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 7 · 2015: 4 · 2014: 2 · 2013: 4 · 2012: 2
FWCI
0.58
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 2930 d)
Locations
  • Diabetic Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Newcastle University ePrints (Newcastle Univesity)
Topics
  • Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
  • Health Sciences › Medicine › Ophthalmology › Ophthalmology and Visual Health Research
  • Health Sciences › Medicine › Ophthalmology › Drug-Induced Ocular Toxicity
Keywords
pupil dilation, acute glaucoma, tropicamide, cycloplegic agents, chronic glaucoma, retinal examination
MeSH terms
Glaucoma, Humans, Mydriatics, Risk Factors, Safety, Tropicamide, Mydriasis

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