Cited by 243Nerve injury and regenerationParkinson's Disease Mechanisms and TreatmentsNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF

Cohen, Ann D., Tillerson, Jennifer L., Smith, Amanda D., Schallert, Timothy, Zigmond, Michael J.·2003·Journal of Neurochemistry

DOI 10.1046/j.1471-4159.2003.01657.x

Open this paper in CoChat — free account

Abstract

Unilateral administration of 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle (MFB) causes a loss of dopamine (DA) in the ipsilateral striatum and contralateral motor deficits. However, if a cast is placed on the ipsilateral limb during the first 7 days following 6-OHDA infusion, forcing the animal to use its contralateral limb, both the behavioral and neurochemical deficits are reduced. Here, we examine the effect of forced reliance on a forelimb during the 7 days prior to ipsilateral infusion of 6-OHDA on the deficits characteristic of this lesion model. Casted animals displayed no behavioral asymmetries as measured 14-28 days postlesion and a marked attenuation in the loss of striatal DA and its metabolites at 30 days. In addition, animals receiving a unilateral cast alone had an increase in glial cell-line derived neurotrophic factor (GDNF) protein in the striatum corresponding to the overused limb. GDNF increased within 1 day after the onset of casting, peaked at 3 days, and returned to baseline within 7 days. These results suggest that preinjury forced limb-use can prevent the behavioral and neurochemical deficits to the subsequent administration of 6-OHDA and that this may be due in part to neuroprotective effects of GDNF.

Integrity signals

Registry

Crossref · 10.1046/j.1471-4159.2003.01657.x

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

GDNF: a Glial Cell Line-Derived Neurotrophic Factor for Midbrain Dopaminergic Neurons
Lin, L.-F. H., Doherty, D. H., Lile, J. D., Bektesh, S. L., & Collins, F. (1993) · Science · doi:10.1126/science.8493557 · Cited by 3,206
Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System
Ungerstedt, U. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.1971.tb11000.x · Cited by 1,920
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
Hyman, C., Hofer, M., Barde, Y., Juhasz, M., Yancopoulos, G. D., Squinto, S. P., & Lindsay, R. M. (1991) · Nature · doi:10.1038/350230a0 · Cited by 1,503
Role of Free Radicals in the Neurodegenerative Diseases: Therapeutic Implications for Antioxidant Treatment
Halliwell, B. (2001) · Drugs & Aging · doi:10.2165/00002512-200118090-00004 · Cited by 1,502
Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
Neeper, S. A., Gómez‐Pinilla, F., Choi, J., & Cotman, C. W. (1996) · Brain Research · doi:10.1016/0006-8993(96)00273-9 · Cited by 1,022
Constraint-Induced Movement Therapy: a new family of techniques with broad application to physical rehabilitation--a clinical review.
Taub, E., Uswatte, G., & Pidikiti, R. D. (1999) · PubMed · Cited by 965
Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
Young, D., Lawlor, P. A., Leone, P., Dragunow, M., & During, M. J. (1999) · Nature Medicine · doi:10.1038/7449 · Cited by 745
Nigrostriatal bundle damage and the lateral hypothalamic syndrome.
Marshall, J. F., Richardson, J. S., & Teitelbaum, P. (1974) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0037223 · Cited by 625
Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy
Carro, E., Trejo, J. L., Busiguina, S., & Torres-Aleman, I. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-15-05678.2001 · Cited by 601
Use-dependent growth of pyramidal neurons after neocortical damage
Jones, T. A., & Schallert, T. J. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02140.1994 · Cited by 508

Show all 52 references

Research works printed but not linked: 2

Paxinos G., 1982, The Rat Brain in Sterotaxic Coordinates
Schallert T., 1989, Preoperative Events: Their Effects on Behavior Following Brain Damage, 1

Sorted by citations

Items 101–200 of 242

Treadmill exercise alleviates nigrostriatal dopaminergic loss of neurons and fibers in rotenone-induced Parkinson rats
Shin, M., Kim, T.-W., Lee, J. M., Ji, E., & Lim, B. (2017) · Journal of Exercise Rehabilitation · doi:10.12965/jer.1734906.453 · Cited by 41
Motor asymmetry and neuromelanin imaging: Concordance in Parkinson's disease
Prasad, S., Saini, J. S., Yadav, R., & Pal, P. K. (2018) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2018.04.022 · Cited by 41
Physical Exercise Attenuates MPTP-Induced Deficits in Mice
Archer, T., & Fredriksson, A. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9168-0 · Cited by 40
The interplay between behavior and neurodegeneration in rat models of Parkinson's disease and stroke
Woodlee, M. T., & Schallert, T. J. (2004) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2004-00281 · Cited by 40
Electroconvulsive shock enhances striatal dopamine D1 and D3 receptor binding and improves motor performance in 6-OHDA-lesioned rats
Strome, E. M., Zis, A. P., & Doudet, D. J. (2007) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0719 · Cited by 39
Behavioral and structural effects of unilateral intrastriatal injections of botulinum neurotoxin a in the rat model of Parkinson's disease
Antipova, V., Hawlitschka, A., Mix, E., Schmitt, O., Dräger, D. L., Benecke, R., & Wree, A. (2013) · Journal of Neuroscience Research · doi:10.1002/jnr.23210 · Cited by 39
A Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson’s Disease
Norwitz, N. G., Dearlove, D., Lü, M., Clarke, K., Dawes, H., & Hu, M. T. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.584130 · Cited by 43
Effect of exercise on dopamine neuron survival in prenatally stressed rats
Mabandla, M. V., Kellaway, L. A., Daniels, W. M. U., & Russell, V. A. (2009) · Metabolic Brain Disease · doi:10.1007/s11011-009-9161-6 · Cited by 38
Alpha‐synuclein at the nexus of genes and environment: the impact of environmental enrichment and stress on brain health and disease
Wassouf, Z., & Schulze-Hentrich, J. M. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14787 · Cited by 36
Treadmill Exercise Attenuates l-DOPA-Induced Dyskinesia and Increases Striatal Levels of Glial Cell-Derived Neurotrophic Factor (GDNF) in Hemiparkinsonian Mice
Speck, A. E., Schamne, M. G., Aguiar, A. S., Cunha, R. A., & Prediger, R. D. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1278-3 · Cited by 36
The carboxyl-terminal domain of the heavy chain of tetanus toxin prevents dopaminergic degeneration and improves motor behavior in rats with striatal MPP+-lesions
Mendieta, L., Venegas, B., Moreno, N., Patricio-Martínez, A., Martínez, I., Aguilera, J., & Limón, I. D. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.06.001 · Cited by 34
Topographic pattern of cortical thinning with consideration of motor laterality in Parkinson disease
Kim, J. S., Yang, J., Lee, J., Youn, J., Kim, J., & Cho, J. W. (2014) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2014.08.021 · Cited by 33
Methylphenidate and environmental enrichment ameliorate the deleterious effects of prenatal stress on attention functioning
Zubedat, S., Aga‐Mizrachi, S., Cymerblit‐Sabba, A., Ritter, A., Nachmani, M., & Avital, A. (2015) · Stress · doi:10.3109/10253890.2015.1023790 · Cited by 32
Brain-dependent movements and cerebral-spinal connections: Key targets of cellular and behavioral enrichment in CNS injury models
Schallert, T. J., & Woodlee, M. T. (2003) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2003.08.0009 · Cited by 30
Exercise-Induced Neuroplasticity: Adaptive Mechanisms and Preventive Potential in Neurodegenerative Disorders
Mansoor, M. A., Ibrahim, A., Hamide, A., Tran, T., Candreva, E., & Baltaji, J. (2025) · Physiologia · doi:10.3390/physiologia5020013 · Cited by 38
Harnessing Cueing Training for Neuroplasticity in Parkinson Disease
van Wegen, E. E. H., Hirsch, M. A., Huiskamp, M., & Kwakkel, G. (2014) · Topics in Geriatric Rehabilitation · doi:10.1097/tgr.0000000000000005 · Cited by 29
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine
Moroz, I. A., Peciña, S., Schallert, T. J., & Stewart, J. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.012 · Cited by 29
Early onset of forced impaired forelimb use causes recovery of forelimb skilled motor function but no effect on gross sensory-motor function after capsular hemorrhage in rats
Ishida, A., Tamakoshi, K., Hamakawa, M., Shimada, H., Nakashima, H., Masuda, T., Hida, H., & Ishida, K. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.06.036 · Cited by 27
A comparison of voluntary and forced exercise in protecting against behavioral asymmetry in a juvenile hemiparkinsonian rat model
Landers, M. R., Kinney, J. W., Allen, D. N., & van Breukelen, F. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.04.002 · Cited by 28
Grip Force Modulation Characteristics as a Marker for Clinical Disease Progression in Individuals With Parkinson Disease: Case-Control Study
Pradhan, S. D., Scherer, R., Matsuoka, Y., & Kelly, V. E. (2014) · Physical Therapy · doi:10.2522/ptj.20130570 · Cited by 28
Handedness does not predict side of onset of motor symptoms in Parkinson's disease
Štochl, J., Hagtvet, K. A., Brožová, H., Klempíř, J., Roth, J., & Růžička, E. (2009) · Movement Disorders · doi:10.1002/mds.22653 · Cited by 27
Rat Models of Vocal Deficits in Parkinson’s Disease
Krasko, M. N., Hoffmeister, J. D., Schaen‐Heacock, N. E., Welsch, J. M., Kelm‐Nelson, C. A., & Ciucci, M. R. (2021) · Brain Sciences · doi:10.3390/brainsci11070925 · Cited by 26
The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
Metta, V., Logishetty, K., Martínez‐Martín, P., Gage, H., Schartau, P., Kaluarachchi, T., Martin, A., Odin, P., Barone, P., Stocchi, F., et al. (2011) · Parkinson s Disease · doi:10.4061/2011/125271 · Cited by 27
Erythropoietin Attenuates Brain Injury, Subventricular Zone Expansion, and Sensorimotor Deficits in Hypoxic-Ischemic Neonatal Rats
Kim, S. S., Lee, K., Sung, D. K., Shim, J. W., Kim, M. J., Jeon, G. W., Chang, Y. S., & Park, W. S. (2008) · Journal of Korean Medical Science · doi:10.3346/jkms.2008.23.3.484 · Cited by 26
FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models
Vidal-Martínez, G., Segura‐Ulate, I., Yang, B. C., Diaz-Pacheco, V., Barragan, J. A., Esquivel, J. D.-L., Chaparro, S. A., Vargas‐Medrano, J., & Perez, R. G. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.113120 · Cited by 26
Exercise-induced rescue of tongue function without striatal dopamine sparing in a rat neurotoxin model of Parkinson disease
Ciucci, M. R., Schaser, A. J., & Russell, J. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.06.004 · Cited by 24
Blueberry juice augments exercise-induced neuroprotection in a Parkinson’s disease model through modulation of GDNF levels
Castro, S. L., Tapias, V., Gathagan, R. J., Emes, A., Brandon, T. E., & Smith, A. D. (2022) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2022.03.001 · Cited by 25
Delayed Exercise-Induced Functional and Neurochemical Partial Restoration Following MPTP
Archer, T., & Fredriksson, A. (2011) · Neurotoxicity Research · doi:10.1007/s12640-011-9261-z · Cited by 24
Nanodelivery of Cerebrolysin and Rearing in Enriched Environment Induce Neuroprotective Effects in a Preclinical Rat Model of Parkinson’s Disease
Requejo, C., Ruíz-Ortega, J. Á., Cepeda, H., Sharma, A., Sharma, H. S., Ozkızılcık, A., Tian, Z. R., Moessler, H., Ugedo, L., & Lafuente, J. V. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0741-x · Cited by 23
Promoting Exercise in Parkinson’s Disease Through community-based Participatory Research
Hirsch, M. A., Iyer, S. S., Englert, D., & Sanjak, M. (2011) · Neurodegenerative Disease Management · doi:10.2217/nmt.11.44 · Cited by 22
Short-term effect of low-, moderate-, and high-intensity exercise training on cerebral dopamine neurotrophic factor (CDNF) and oxidative stress biomarkers in brain male Wistar rats
Shirvani, H., Aslani, J., Mohammadi, Z. F., & Arabzadeh, E. (2019) · Comparative Clinical Pathology · doi:10.1007/s00580-018-2885-0 · Cited by 22
Closing the gap between clinic and cage: Sensori-motor and cognitive behavioural testing regimens in neurotoxin-induced animal models of Parkinson's disease
Pienaar, I. S., Lu, B., & Schallert, T. J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.07.009 · Cited by 25
Forced exercise before or after induction of 6-OHDA-mediated nigrostriatal insult does not mitigate behavioral asymmetry in a hemiparkinsonian rat model
Landers, M. R., Kinney, J. W., & van Breukelen, F. (2013) · Brain Research · doi:10.1016/j.brainres.2013.10.054 · Cited by 22
Vocal training, levodopa, and environment effects on ultrasonic vocalizations in a rat neurotoxin model of Parkinson disease
Kelm‐Nelson, C. A., Brauer, A. F. L., & Ciucci, M. R. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.03.006 · Cited by 22
Motor response to amphetamine treatment, task-specific training, and limited motor experience in a postacute animal stroke model
Brown, A. W., Bjelke, B., & Fuxé, K. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.07.005 · Cited by 22
Taking sides: Is handedness involved in motor asymmetry of Parkinson's disease?
Melamed, E., & Poewe, W. H. (2012) · Movement Disorders · doi:10.1002/mds.24048 · Cited by 22
Lateralization of Motor Signs Affects Symptom Progression in Parkinson Disease
Elkurd, M. T., Wang, J., & Dewey, R. B. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.711045 · Cited by 21
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons
Frau, L., Morelli, M., & Simola, N. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.03.002 · Cited by 22
Combination of Human Mesenchymal Stem Cells and Repetitive Transcranial Magnetic Stimulation Enhances Neurological Recovery of 6-Hydroxydopamine Model of Parkinsonian’s Disease
Lee, J. Y., Kim, H. S., Kim, S. H., Kim, H.-S., & Cho, B. P. (2020) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-019-00233-8 · Cited by 21
Cytokine-, Neurotrophin-, and Motor Rehabilitation-Induced Plasticity in Parkinson’s Disease
Policastro, G., Brunelli, M., Tinazzi, M., Chiamulera, C., Emerich, D. F., & Paolone, G. (2020) · Neural Plasticity · doi:10.1155/2020/8814028 · Cited by 21
Physiotherapy in Parkinson's disease patients: Recommendations for clinical practice
Redecker, C., Bilsing, A., Csóti, I., Fogel, W., Ebersbach, G., Hauptmann, B., Hellwig, B., & Müngersdorf, M. (2014) · Basal Ganglia · doi:10.1016/j.baga.2014.03.001 · Cited by 23
Development and validation of a yoga module for Parkinson disease
Kakde, N., Metri, K., Varambally, S. S., Raghuram, N., & Nagendra, H. R. (2017) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2015-0112 · Cited by 20
Nigrostriatal interaction in the aging brain: new therapeutic target for Parkinson’s disease
Błaszczyk, J. W. (2017) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2017-041 · Cited by 20
Neuroprotective strategies to prevent and treat Parkinson’s disease based on its pathophysiological mechanism
Lee, Y., Kim, M., & Lee, J. (2017) · Archives of Pharmacal Research · doi:10.1007/s12272-017-0960-8 · Cited by 22
Assessment of recovery in the hemiparkinson rat: Drug-induced rotation is inadequate
Castañeda, E., FLEMING, S., Paquette, M. A., BOAT, K., MOFFETT, J., Stachowiak, E. K., Bloom, D. A., & Stachowiak, M. K. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.01.019 · Cited by 20
Relationship between risk and protective factors and clinical features of Parkinson's disease
Belvisi, D., Pellicciari, R., Fabbrini, A., Costanzo, M., Ressa, G., Pietracupa, S., Lucia, M. D., Modugno, N., Magrinelli, F., Dallocchio, C., et al. (2022) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2022.04.017 · Cited by 19
Botulinum Neurotoxin A Injected Ipsilaterally or Contralaterally into the Striatum in the Rat 6-OHDA Model of Unilateral Parkinson’s Disease Differently Affects Behavior
Antipova, V., Holzmann, C., Schmitt, O., Wree, A., & Hawlitschka, A. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00119 · Cited by 19
Exercise Promotes Neurite Extensions from Grafted Dopaminergic Neurons in the Direction of the Dorsolateral Striatum in Parkinson’s Disease Model Rats
Torikoshi, S., Morizane, A., Shimogawa, T., Samata, B., Miyamoto, S., & Takahashi, J. B. (2020) · Journal of Parkinson s Disease · doi:10.3233/jpd-191755 · Cited by 19
Neurorééducation des syndromes parkinsoniens
Graciès, J. (2010) · Revue Neurologique · doi:10.1016/j.neurol.2009.10.026 · Cited by 22
Towards New Therapies for Parkinson's Disease
Finkelstein, D. I. (2011) · InTech eBooks · doi:10.5772/954 · Cited by 19
Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease
Schlachetzki, J. C. M., Marxreiter, F., Regensburger, M., Kulinich, A. O., Winner, B., & Winkler, J. (2014) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-130371 · Cited by 19
Handedness and dominant side of symptoms in Parkinson's disease
Shi, J. R., Liu, J., & Qu, Q. (2013) · Medicina Clínica · doi:10.1016/j.medcli.2012.11.028 · Cited by 18
No Pain, No Gain: Lack of Exercise Obstructs Neurogenesis
Watson, N., Ji, X., Yasuhara, T., Date, I., Kaneko, Y., Tajiri, N., & Borlongan, C. V. (2015) · Cell Transplantation · doi:10.3727/096368915x687723 · Cited by 18
Exercise for Older Adults Improves the Quality of Life in Parkinson’s Disease and Potentially Enhances the Immune Response to COVID-19
Hall, M.-F. E., & Church, F. (2020) · Brain Sciences · doi:10.3390/brainsci10090612 · Cited by 17
Management of the behavioral aspects of Parkinson’s disease
Borek, L. L., Chou, K. L., & Friedman, J. H. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.6.711 · Cited by 18
The Role of Exercise in Facilitating Basal Ganglia Function in Parkinson’s Disease
Petzinger, G. M., Fisher, B. E., Akopian, G. K., Holschneider, D. P., Wood, R. I., Walsh, J. P., Lund, B. T., Meshul, C. K., Vuckovic, M. G., & Jakowec, M. W. (2011) · Neurodegenerative Disease Management · doi:10.2217/nmt.11.16 · Cited by 16
Beneficial effects of an innovative exercise model on motor and oxidative disorders induced by haloperidol in rats
Teixeira, A. I., Müller, L. G., Reckziegel, P., Boufleur, N., Pase, C. S., Villarinho, J. G., Fachinetto, R., Ferreira, J., da Rocha, J. B. T., & Bürger, M. E. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.10.017 · Cited by 15
Triggering endogenous neuroprotective mechanisms in Parkinson’s disease: studies with a cellular model
Zigmond, M. J. (2006) · Springer eBooks · doi:10.1007/978-3-211-45295-0_66 · Cited by 15
Levodopa therapy from the neuroprotection viewpoint
Kondo, T. (2005) · Journal of Neurology · doi:10.1007/s00415-005-4007-6 · Cited by 15
Minor neuronal damage and recovered cellular proliferation in the hippocampus after continuous unilateral forelimb restraint in normal rats
Ishida, A., Ueda, Y., Ishida, K., Misumi, S., Masuda, T., Fujita, M., & Hida, H. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22566 · Cited by 14
Pharmacogenomics and Personalized Medicine in Parkinsonism
Archer, T., & Fredriksson, A. (2013) · Springer eBooks · doi:10.1007/978-81-322-1184-6_14 · Cited by 13
Comparison of voluntary and forced exercise effects on motor behavior in 6-hydroxydopamine-lesion rat model of Parkinson’s disease
Sheibani, V., Rafie, F., Shahbazi, M., Naghdi, N., & Sheikh, M. (2017) · Sport Sciences for Health · doi:10.1007/s11332-017-0354-9 · Cited by 13
Basal ganglia disorders
Melnick, M. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-323-07586-2.00029-7 · Cited by 13
Handedness associated to side of onset of Parkinson's disease?
van Rooden, S. M., Jeukens‐Visser, M., Verbaan, D., & Marinus, J. (2008) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2008.11.002 · Cited by 11
Physical Exercise as Intervention in Parkinsonism
Archer, T., & Fredriksson, A. (2014) · Springer eBooks · doi:10.1007/978-1-4614-5836-4_105 · Cited by 10
Targeted Motor Rehabilitation Dissociates Corticobulbar Versus Corticospinal Dysfunction in an Animal Model of Parkinson’s Disease
Plowman, E. K., Maling, N., Thomas, N. J., Fowler, S. C., & Kleim, J. A. (2013) · Neurorehabilitation and neural repair · doi:10.1177/1545968313498648 · Cited by 10
Amelioration of l-Dopa-Associated Dyskinesias with Triterpenoic Acid in a Parkinsonian Rat Model
Ndlovu, B., Daniels, W. M. U., & Mabandla, M. V. (2015) · Neurotoxicity Research · doi:10.1007/s12640-015-9567-3 · Cited by 10
Dysphagia in Parkinson Disease: Part II—Current Treatment Options and Insights from Animal Research
Krasko, M. N., Rudisch, D. M., Burdick, R. J., Schaen‐Heacock, N. E., Broadfoot, C. K., Nisbet, A. F., Rogus‐Pulia, N. M., & Ciucci, M. R. (2023) · Current Physical Medicine and Rehabilitation Reports · doi:10.1007/s40141-023-00393-8 · Cited by 10
Detrimental effects of physical inactivity on neurogenesis
Lippert, T., Watson, N., Ji, X., Yasuhara, T., Date, I., Kaneko, Y., Tajiri, N., & Borlongan, C. V. (2016) · Brain Circulation · doi:10.4103/2394-8108.186278 · Cited by 9
Amphetamine-evoked rotation requires newly synthesized dopamine at 14 days but not 1 day after intranigral 6-OHDA and is consistently dissociated from sensorimotor behavior
Paquette, M. A., Marsh, S. T., Hutchings, J. E., & Castañeda, E. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.01.017 · Cited by 9
Combined ipsilateral limb use score as an index of motor deficits and neurorestoration in parkinsonian rats
Leikas, J. V., Kääriäinen, T. M., Jalkanen, A. J., Lehtonen, M., Rantamäki, T., & Forsberg, M. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24022 · Cited by 10
Morphological Changes in a Severe Model of Parkinson’s Disease and Its Suitability to Test the Therapeutic Effects of Microencapsulated Neurotrophic Factors
Requejo, C., Ruíz-Ortega, J. Á., Bengoetxea, H., García-Blanco, A., Herrán, E., Aristieta, A., Igartúa, M., Pedraz, J. L., Ugedo, L., Hernández, R. M., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0244-1 · Cited by 8
Resilience and Survival in Extreme Environments
Friedl, K. E., & Penetar, D. M. (2008) · CRC Press eBooks · doi:10.1201/9781420071788.ch7 · Cited by 9
Cueing training in persons with Parkinson's disease
Hirsch, M. A., & Hammond, F. M. (2007) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2006.104794 · Cited by 8
The influence of motor asymmetry on cognitive functions in Parkinson’s disease
Coloman, I. I., & Chimagomedova, A. S. (2020) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202012010274 · Cited by 7
Regenerative Therapy in Experimental Parkinsonism: Mixed Population of Differentiated Mouse Embryonic Stem Cells, Rather Than Magnetically Sorted and Enriched Dopaminergic Cells Provide Neuroprotection
Tripathy, D., Verma, P., Nthenge-Ngumbau, D. N., Banerjee, M., & Mohanakumar, K. P. (2014) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12295 · Cited by 7
Physical interventions for people with Parkinson's disease: a systematic review and network meta-analysis
Roheger, M., Ernst, M., Folkerts, A., Krohm, F., Liebermann‐Jordanidis, H., Chakraverty, D., Droz, M., Adams, A., Eggers, C., Monsef, I., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013856 · Cited by 8
EFFECTS OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) ON STEM/PROGENITOR CELL PROLIFERATION AND DIFFERENTIATION
Chen, Y. (2005) · UKnowledge (University of Kentucky) · Cited by 4
Effects of Balance and Gait Training on the Recovery of the Motor Function in an Animal Model of Parkinson’s Disease
Yoon, Y.-J., & Lee, B. (2014) · Journal of Physical Therapy Science · doi:10.1589/jpts.26.905 · Cited by 6
Effects of Voluntary Exercise on Motor Function in Parkinson's disease Model of Rats
Rafie, F., Shabazi, M., Sheikh, M., Naghdi, N., & Sheibani, V. (2017) · Annals of Applied Sport Science · doi:10.18869/acadpub.aassjournal.5.2.81 · Cited by 6
Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine -induced Parkinson in male NMRI mice.
Nazif, N. N., Khosravi, M., Ahmadi, R., Bananej, M., & Majd, A. (2020) · PubMed Central · doi:10.22038/ijbms.2020.37707.8960 · Cited by 6
VIBRATION TRAINING IN REHABILITATION
Schmidtbleicher, D., Haas, C. T., & Turbanski, S. (2005) · ISBS - Conference Proceedings Archive · Cited by 6
Early pubertal female rats are more resistant than males to 6-hydroxydopamine neurotoxicity and behavioural deficits: A possible role for trophic factors
Pienaar, I. S., Schallert, T. J., Russell, V. A., Kellaway, L. A., Carr, J. A., & Daniels, W. M. U. (2007) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2007-00408 · Cited by 6
Running wheel exercise before a binge regimen of methamphetamine does not protect against striatal dopaminergic damage
O’Dell, S. J., & Marshall, J. F. (2014) · Synapse · doi:10.1002/syn.21754 · Cited by 5
Limiting exercise inhibits neuronal recovery from neurological disorders
Yasuhara, T., Anthony, S., & Date, I. (2017) · Brain Circulation · doi:10.4103/bc.bc_16_17 · Cited by 5
Pre-diagnosis physical activity habits are associated with age of diagnosis in Parkinson's disease
Landers, M. R., Johnson, K. N., Johnson, S., Ormsby, T., Salgo, D. C., Zorn, J. B., Lyle, J., Murtishaw, A. S., Salazar, A., & Kinney, J. W. (2019) · Clinical Parkinsonism & Related Disorders · doi:10.1016/j.prdoa.2019.07.004 · Cited by 7
Physical therapy in Parkinson's disease
Graciès, J., Tse, W., Lugassy, M. M., & FRANK, J. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)84030-9 · Cited by 5
Effects of Exercise on Structural and Functional Changes in the Aging Brain
Lee, K. J., & Rhyu, I. J. (2009) · Journal of Korean Medical Association · doi:10.5124/jkma.2009.52.9.907 · Cited by 5
Medical Treatment of Parkinson Disease
Fahn, S., Jankovic, J. J., Hallett, M., & Jenner, P. G. (2007) · Elsevier eBooks · doi:10.1016/b978-0-443-07941-2.50009-7 · Cited by 4
Parkinson's disease with a predominant right-sided putaminal FP-CIT SPECT deficiency shows stronger decline of asymmetry over time
Pedrosa, D. J., Kahraman, D., Schmidt, M., Drzezga, A. E., Timmermann, L., & Eggers, C. (2014) · Basal Ganglia · doi:10.1016/j.baga.2014.08.001 · Cited by 4
Current Problems and Strategies in Motor Rehabilitation for Parkinson’s Disease
Abbruzzese, G., Pelosin, E., & Marchese, R. (2007) · Springer eBooks · doi:10.1007/978-0-387-72076-0_4 · Cited by 4
Exercise: A workout for neuroregeneration
Azizi, S. A., & Vendrame, M. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.03.057 · Cited by 4
Neuroprotection by Physical Activity
Mitchell, A. (2010) · Cited by 4
Development of disease-specific qigong program for Parkinson's disease
Lee, H., Lee, H., Yin, C.-S., Chae, Y., Baik, Y.-S., Shin, Y. C., Lee, S.-J., & Park, H. (2009) · Korean Journal of Acupuncture · Cited by 4
Parkinson-Syndrom
Reuter, I., & Knapp, G. (2015) · Elsevier eBooks · doi:10.1016/b978-3-437-24265-6.00004-4 · Cited by 4
Functional Suppression of Premotor Activity in a Transient Model of Motor Cortex InjuryPreprint
Elliott, K. C., Borrell, J. A., Barbay, S., & Nudo, R. J. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.12.148403 · Cited by 4
Parkinson's Disease: Cell Vulnerability and Disease Progression
de Tassigny, X. D., Pascual, A., & López‐Barneo, J. (2015) · Frontiers research topics · doi:10.3389/978-2-88919-676-0 · Cited by 3
The Association between Motor Laterality and Cognitive Impairment in Parkinson’s Disease
Yoon, J. E., Kim, J. S., Seo, J.-Y., Cho, J. W., Sunwoo, J., Lee, K. B., Roh, H., & Ahn, M. (2016) · Dementia and Neurocognitive Disorders · doi:10.12779/dnd.2016.15.4.142 · Cited by 3
The Effects of Four Weeks of Chiropractic Spinal Adjustments on Blood Biomarkers in Adults with Chronic Stroke: Secondary Outcomes of a Randomized Controlled Trial
Haavik, H., Niazi, I. K., Amjad, I., Kumari, N., Rashid, U., Duehr, J., Navid, M. S., Trager, R. J., Shafique, M. S., & Holt, K. R. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247493 · Cited by 3
Assessment von neurologischen Gangstörungen
Schwed, M. A., Kersten, S., Scholl, N., & Haas, C. (2009) · B&G Bewegungstherapie und Gesundheitssport · doi:10.1055/s-0028-1098781 · Cited by 4

Authors: Cohen, A. D., Tillerson, J. L., Smith, A. D., Schallert, T., & Zigmond, M. J.
Affiliations: University of Pittsburgh (US)
The University of Texas at Austin (US)
University of Michigan (US)
Corresponding author: Zigmond, Michael J.
ORCID: Cohen, Ann D.
Venue: Journal of Neurochemistry
Publisher: Wiley
Published: 2003-04
Volume: 85
Issue: 2
Pages: 299-305
ISSN: 0022-3042 (ISSN-L)
1471-4159
DOI: 10.1046/j.1471-4159.2003.01657.x
OpenAlex: W2131124574
Cited by: 243
References: 52
Citations by year: 2026: 3 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 12 · 2019: 7 · 2018: 11 · 2017: 13 · 2016: 10 · 2015: 11 · 2014: 17 · 2013: 19 · 2012: 5
FWCI: 4.27
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 1 d)
Locations: Journal of Neurochemistry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01ns023979-15)
U.S. Public Health Service
National Institute of Mental Health (MH-29670)
National Institute of Neurological Disorders and Stroke (NS 19608, NS 23979, T32NS007433, NS 07433)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: 6-hydroxydopamine, medial forebrain bundle lesion, dopamine depletion, striatum, glial cell line-derived neurotrophic factor, neuroprotection, motor impairment, behavioral asymmetry, dopamine metabolites
MeSH terms: Animals, Apomorphine, Behavior, Animal, Casts, Surgical, Corpus Striatum, Disease Models, Animal, Dopamine, Forelimb, Immobilization, Functional Laterality, Male, Medial Forebrain Bundle, Motor Activity, Nerve Growth Factors, Parkinson Disease, Secondary, 3,4-Dihydroxyphenylacetic Acid, Oxidopamine, Rats, Sprague-Dawley, Rats, Long-Evans, Glial Cell Line-Derived Neurotrophic Factor, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks