The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Wound bed preparation: a systematic approach to wound management
Abstract
The healing process in acute wounds has been extensively studied and the knowledge derived from these studies has often been extrapolated to the care of chronic wounds, on the assumption that nonhealing chronic wounds were simply aberrations of the normal tissue repair process. However, this approach is less than satisfactory, as the chronic wound healing process differs in many important respects from that seen in acute wounds. In chronic wounds, the orderly sequence of events seen in acute wounds becomes disrupted or “stuck” at one or more of the different stages of wound healing. For the normal repair process to resume, the barrier to healing must be identified and removed through application of the correct techniques. It is important, therefore, to understand the molecular events that are involved in the wound healing process in order to select the most appropriate intervention. Wound bed preparation is the management of a wound in order to accelerate endogenous healing or to facilitate the effectiveness of other therapeutic measures. Experts in wound management consider that wound bed preparation is an important concept with significant potential as an educational tool in wound management. This article was developed after a meeting of wound healing experts in June 2002 and is intended to provide an overview of the current status, role, and key elements of wound bed preparation. Readers will be able to examine the following issues; • the current status of wound bed preparation; • an analysis of the acute and chronic wound environments; • how wound healing can take place in these environments; • the role of wound bed preparation in the clinic; • the clinical and cellular components of the wound bed preparation concept; • a detailed analysis of the components of wound bed preparation. (WOUND REP REG 2003;11:1–28)
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Citations
Cites
Chemokines in cutaneous wound healing
Gillitzer, R., & Goebeler, M. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.69.4.513 · Cited by 943
Interactions of cytokines, growth factors, and proteases in acute and chronic wounds
Mast, B. A., & Schultz, G. S. (1996) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.1996.40404.x · Cited by 598 · cited 1×
“There is often a pro-inflammatory stimulus due to necrotic tissue, a heavy bacterial burden, and tissue breakdown that causes cellular and biochemical changes in the wound bed such as increased levels of MMPs, which degrade the ECM and result in impaired cell migration and deposition of connective tissue.(29) MMPs als…”
BackgroundSelf-citation
Cited by
Edwards, R., & Harding, K. G. (2004) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200404000-00004 · Cited by 1,099
Self-citationWound healing and treating wounds
Morton, L. M., & Phillips, T. J. (2016) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2015.08.068 · Cited by 475
Chronic wounds: Current status, available strategies and emerging therapeutic solutions
Las Heras, K., Igartua, M., Santos-Vizcaino, E., & Hernandez, R. M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.039 · Cited by 370
Challenges in the management of chronic wound infections
Falcone, M., De Angelis, B., Pea, F., Scalise, A., Stefani, S., Tasinato, R., Zanetti, O., & Dalla Paola, L. (2021) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2021.05.010 · Cited by 339
Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds
Schultz, G., Bjarnsholt, T., James, G. A., Leaper, D. J., McBain, A. J., Malone, M., Stoodley, P., Swanson, T., Tachi, M., Wolcott, R. D., et al. (2017) · Wound Repair and Regeneration · doi:10.1111/wrr.12590 · Cited by 337
Self-citationTreatment of Pressure Ulcers: A Systematic Review
Reddy, M., Gill, S. S., Kalkar, S. R., Wu, W., Anderson, P. J., & Rochon, P. A. (2008) · JAMA · doi:10.1001/jama.2008.778 · Cited by 266
Nusbaum, A. G., Gil, J., Rippy, M. K., Warne, B., Valdes, J., Claro, A., & Davis, S. C. (2012) · Journal of Surgical Research · doi:10.1016/j.jss.2011.11.1040 · Cited by 75
Pukstad, B. S., Ryan, L., Flo, T. H., Stenvik, J., Moseley, R., Harding, K., Thomas, D. W., & Espevik, T. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2010.05.003 · Cited by 65
Self-citationNasole, E., Nicoletti, C., Yang, Z.-J., Girelli, A., Rubini, A., Giuffreda, F., Di Tano, A., Camporesi, E., & Bosco, G. (2014) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2012.759951 · Cited by 39
Metadata
- Authors
- Schultz, G. S., Sibbald, R. G., Falanga, V., Ayello, E. A., Dowsett, C., Harding, K., Romanelli, M., Stacey, M. C., Teot, L., & Vanscheidt, W.
- Venue
- Wound Repair and Regeneration
- Publisher
- Wiley
- Published
- 2003-03
- Volume
- 11
- Issue
- s1
- Pages
- S1-28
- ISSN
- 1067-1927 (ISSN-L)
- 1524-475X
- OpenAlex
- W2120033284
- Cited by
- 1,434
- References
- 2
- FWCI
- 38.80
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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