Cited by 640Fatty Acid Research and HealthEdible Oils Quality and AnalysisNutritional Studies and Diet

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Dietary fatty acids and human health

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Williams, Christine M.·2000·Annales de Zootechnie

DOI 10.1051/animres:2000116

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Abstract

A considerable amount of evidence has accumulated to support the view that the very long chain omega 3 fatty acids (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) have beneficial cardiovascular and anti-inflammatory properties and that levels of their consumption are insufficient in most Western diets.More recently, attention has been given to the possibility that the precursor omega-3 PUFA, alpha linolenic acid (ALNA), may share some of the beneficial actions of EPA/DHA on human health.Further research into the metabolism and physiological actions of ALNA, and comparisons with EPA/DHA, is needed before conclusions regarding the optimal amounts and types of omega-3 PUFA for human health can be defined.Conjugated linoleic acid (CLA), which arises as a metabolic by-product of rumen hydrogenation and which is found in foods of animal origin, has been proposed to possess potent health promoting properties, but much of this research has been conducted in experimental animals.There is an urgent need for complementary studies in human volunteers, to confirm the putative anti-carcinogenic, anti-atherogenic, anti-lipogenic and immuno-suppressive properties of CLA.human health / fatty acids / omega-3 PUFA / conjugated linoleic acid Résumé -Acides gras alimentaires et santé humaine.Il a été amplement démontré que les acides gras à très longue chaîne en oméga 3, les acides eicoapentaenoïque (EPA) et decosahexaenoïque (DHA) ont des effets positifs relatifs à l'apparition des maladies cardio-vasculaires, et des propriété anti-inflammatoires.Leur consommation par l'Homme est insuffisante dans la plupart des pays occidentaux.Récemment il est apparu que l'acide alpha linolénique, précurseur des acides gras en oméga 3, pouvait partager avec l'EPA et le DHA certains effets positifs sur la santé humaine.Des recherches complémentaires sur le métabolisme et le rôle physiologique de l'acide alpha linolénique, ainsi que des comparaisons avec l'EPA et le DHA sont nécessaires avant de pouvoir définir les apports recommandés optimaux de chacun de ces acides gras.L'acide linoléique conjugué (CLA) qui provient du métabolisme ruminal des acides gras et qui est présent dans les aliments d'origine animale, a été décrit comme potentiellement favorable à la santé humaine, mais la plupart des expérimentations ont été conduites sur animaux de laboratoire.Il y a une urgence à réaliser des études complémentaires sur des volontaires humains, afin de confirmer les propriétés annoncées du CLA, à savoir des effets anti-carcinogène, anti-athérogène, anti-lipogénique et une modulation de l'immunité.santé humaine / acides gras / oméga-3 PUFA / acide linoléique conjugué

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Authors: Williams, C. M.
Affiliations: University of Reading (GB)
Corresponding author: Williams, Christine M.
Venue: Annales de Zootechnie
Publisher: EDP Sciences
Published: 2000-05
Volume: 49
Issue: 3
Pages: 165-180
ISSN: 0003-424X (ISSN-L)
1297-9651
DOI: 10.1051/animres:2000116
OpenAlex: W2167208210
Cited by: 640
References: 107
Citations by year: 2026: 3 · 2025: 9 · 2024: 11 · 2023: 18 · 2022: 19 · 2021: 25 · 2020: 37 · 2019: 32 · 2018: 24 · 2017: 26 · 2016: 40 · 2015: 39 · 2014: 33 · 2013: 39 · 2012: 33
FWCI: 8.27
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Annales de Zootechnie (publishedVersion)
Springer Link (Chiba Institute of Technology) (submittedVersion)
HAL (submittedVersion, other-oa)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: dietary fatty acids, omega-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid, alpha-linolenic acid, conjugated linoleic acid, cardiovascular health, anti-inflammatory activity, dietary intake, anti-carcinogenic effects, Western diet, dietary recommendations

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