The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Kingdom-Agnostic Metagenomics and the Importance of Complete Characterization of Enteric Microbial Communities
Open accessAbstract
Advanced sequencing techniques have shown that bacteria are not the only complex and important microbes in the human intestine. Non-bacterial organisms, particularly the virome and the mycobiome, are important regulators of intestinal immunity and inflammation. The virome is mucosal and systemic; it can alter the host response to bacteria and interact with host genes and bacteria to contribute to disease pathogenesis. The human mycobiome is also complex and can contribute to intestinal inflammation. We review what has recently been learned about the non-bacterial and non-archaeal microbes in the gastrointestinal tract, discussing their potential effects on health and disease and analytical approaches for their study. Studies of associations between the microbiome and intestinal pathology should incorporate kingdom-agnostic approaches if we are to fully understand intestinal health and disease.
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Cites
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Cited by
Lloyd-Price, J., Abu-Ali, G., & Huttenhower, C. (2016) · Genome Medicine · doi:10.1186/s13073-016-0307-y · Cited by 1,891
Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease
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Self-citationThe role of the gut microbiota in NAFLD
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Metadata
- Authors
- Norman, J. M., Handley, S. A., & Virgin, H. W.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 146
- Issue
- 6
- Pages
- 1459-1469
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2043289135
- Cited by
- 191
- References
- 13
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Norman, J. M., Handley, S. A., & Virgin, H. W. (2014). Kingdom-Agnostic Metagenomics and the Importance of Complete Characterization of Enteric Microbial Communities. Gastroenterology. https://doi.org/10.1053/j.gastro.2014.02.001
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.