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Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM)—Juni 2021—AWMF-Registriernummer: 021/016

Layer, P., Andresen, V., Allescher, H., Bischoff, S. C., Claßen, M., Elsenbruch, S., Freitag, M., Frieling, T., Gebhard, M., Goebel-Stengel, M., Häuser, W., Holtmann, G., Keller, J., Kreis, M. E., Kruis, W., Langhorst, J., Jansen, P. Lynen, Madisch, A., Mönnikes, H., Müller-Lissner, S., Niesler, B., Pehl, C., Pohl, D., Raithel, M., Röhrig-Herzog, G., Schemann, M., Schmiedel, S., Schwille-Kiuntke, J., Storr, M., Preiß, J. C., Andus, T., Buderus, S., Ehlert, U., Engel, M., Enninger, A., Fischbach, W., Gillessen, A., Gschossmann, J., Gundling, F., Haag, S., Helwig, U., Hollerbach, S., Karaus, M., Katschinski, M., Krammer, H., Kuhlbusch-Zicklam, R., Matthes, H., Menge, D., Miehlke, S., Posovszky, M. C., Schaefert, R., Schmidt-Choudhury, A., Schwandner, O., Schweinlin, A., Seidl, H., Stengel, A., Tesarz, J., van der Voort, I., Voderholzer, W., von Boyen, G., von Schönfeld, J., Wedel, T., Collaborators:, in Zusammenarbeit mit:, Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM), Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI), Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV), Deutsche Gesellschaft für Ernährungsmedizin (DGEM), Deutsche Gesellschaft für Geriatrie (DGG), Deutsche Gesellschaft für Innere Medizin (DGIM), Deutsche Gesellschaft für Naturheilkunde (DGNHK), Deutsche Gesellschaft für Pathologie und Bundesverband deutscher Pathologen e. V. (DGP/BDP), Deutsche Gesellschaft für Psychosomatische Medizin und Ärztliche Psychotherapie (DGPM), Deutsche Gesellschaft für Verhaltensmedizin und Verhaltensmodifikation (DGVM), Deutsche Schmerzgesellschaft e. V., Deutsches Kollegium für Psychosomatische Medizin (DKPM), Deutsche Gesellschaft für Tropenmedizin und Internationale Gesundheit (DTG), Gesellschaft für Pädiatrische Gastroenterologie und Ernährung (GPGE), Deutschen Gesellschaft für Kinder- und Jugendmedizin (DGKJ), Swiss Society of Neurogastroenterology and Motility (SwissNGM), Informationsforum für Patient:innen mit Magen-Darm-Erkrankungen (MAGDA)·2021·Zeitschrift für Gastroenterologie
DOI 10.1055/a-1591-4794
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  1. P Layer, 2011, [Irritable bowel syndrome: German consensus guidelines on definition, pathophysiology and management], Z Gastroenterol, 49, 237
  2. N J Talley, 1999, Irritable bowel syndrome: definition, diagnosis and epidemiology, Baillieres Best Pract Res Clin Gastroenterol, 13, 371, 10.1053/bega.1999.0033 · DOI
  3. A P Manning, 1978, Towards positive diagnosis of the irritable bowel, Br Med J, 2, 653, 10.1136/bmj.2.6138.653 · DOI · Paper page
  4. W Kruis, 1984, A diagnostic score for the irritable bowel syndrome. Its value in the exclusion of organic disease, Gastroenterology, 87, 1, 10.1016/0016-5085(84)90119-7 · DOI
  5. W G Thompson, 1989, Irritable bowel syndrome: guidelines for the diagnosis, Gastroenterol Int, 2, 92
  6. B E Lacy, 2016, Bowel Disorders, Gastroenterology, 150, 1393, 10.1053/j.gastro.2016.02.031 · DOI · Paper page
  7. W G Thompson, 1984, Gastrointestinal symptoms in the irritable bowel compared with peptic ulcer and inflammatory bowel disease, Gut, 25, 1089, 10.1136/gut.25.10.1089 · DOI
  8. N J Talley, 1990, Diagnostic value of the Manning criteria in irritable bowel syndrome, Gut, 31, 77, 10.1136/gut.31.1.77 · DOI
  9. K P Rao, 1993, Evaluation of Manning’s criteria in the diagnosis of irritable bowel syndrome, J Assoc Physicians India, 41, 357
  10. H Jeong, 1993, Manning criteria in irritable bowel syndrome: its diagnostic significance, Korean J Intern Med, 8, 34, 10.3904/kjim.1993.8.1.34 · DOI
  11. J Hotz, 1999, [Consensus report: irritable bowel syndrome – definition, differential diagnosis, pathophysiology and therapeutic possibilities. Consensus of the German Society of Digestive and Metabolic Diseases], Z Gastroenterol, 37, 685
  12. M Simren, 2017, Update on Rome IV Criteria for Colorectal Disorders: Implications for Clinical Practice, Curr Gastroenterol Rep, 19, 15, 10.1007/s11894-017-0554-0 · DOI
  13. P Enck, 2017, Irritable bowel syndrome – dissection of a disease. A 13-steps polemic, Z Gastroenterol, 55, 679, 10.1055/s-0043-110574 · DOI
  14. B E Lacy, 2005, Irritable bowel syndrome: a syndrome in evolution, J Clin Gastroenterol, 39, S230, 10.1097/01.mcg.0000156110.69232.bb · DOI
  15. J Howship, 1830, Practical remarks on the discrimination and successful treatment of spasmodic stricture in the colon considered as an occasional cause of habitual confinement of the bowel
  16. J M Da Costa, 1871, Mucous enteritis, Am J Med Sci, 62, 321, 10.1097/00000441-187110000-00001 · DOI
  17. P R Maxwell, 1997, Irritable bowel syndrome, Lancet, 350, 1691, 10.1016/S0140-6736(97)05276-8 · DOI
  18. H L Bockus, 1928, Neurogenic mucous colitis, Am J Med Sci, 176, 813, 10.1097/00000441-192812000-00006 · DOI
  19. J A Ryle, 1928, Chronic spasmodic afflictions of the colon, Lancet II, 212, 1115
  20. B J Smits, 1974, The irritable bowel syndrome, Practitioner, 213, 37
  21. N A Chaudhary, 1962, The irritable colon syndrome. A study of the clinical features, predisposing causes, and prognosis in 130 cases, Q J Med, 31, 307
  22. T Frieling, 2011, [Irritable bowel syndrom – a misnomer?], Z Gastroenterol, 49, 577
  23. M von Wulffen, 2019, Overlap of Irritable Bowel Syndrome and Functional Dyspepsia in the Clinical Setting: Prevalence and Risk Factors, Dig Dis Sci, 64, 480, 10.1007/s10620-018-5343-6 · DOI
  24. R Spiller, 2007, Guidelines on the irritable bowel syndrome: mechanisms and practical management, Gut, 56, 1770, 10.1136/gut.2007.119446 · DOI · Paper page
  25. A Blewett, 1996, Psychiatric disorder and outcome in irritable bowel syndrome, Psychosomatics, 37, 155, 10.1016/S0033-3182(96)71582-7 · DOI
  26. R C Smith, 1990, Psychosocial factors are associated with health care seeking rather than diagnosis in irritable bowel syndrome, Gastroenterology, 98, 293, 10.1016/0016-5085(90)90817-K · DOI
  27. N A Koloski, 2001, Predictors of health care seeking for irritable bowel syndrome and nonulcer dyspepsia: a critical review of the literature on symptom and psychosocial factors, Am J Gastroenterol, 96, 1340, 10.1111/j.1572-0241.2001.03789.x · DOI · Paper page
  28. G R Locke 3rd, 2004, Psychosocial factors are linked to functional gastrointestinal disorders: a population based nested case-control study, Am J Gastroenterol, 99, 350, 10.1111/j.1572-0241.2004.04043.x · DOI · Paper page
  29. R Jones, 1992, Irritable bowel syndrome in the general population, BMJ, 304, 87, 10.1136/bmj.304.6819.87 · DOI
  30. K W Heaton, 1993, Bowel function and irritable bowel symptoms after hysterectomy and cholecystectomy – a population based study, Gut, 34, 1108, 10.1136/gut.34.8.1108 · DOI
  31. J Kettell, 1992, Reasons for consultation in irritable bowel syndrome: symptoms and patient characteristics, Br J Gen Pract, 42, 459
  32. G A Donker, 1999, Patients with irritable bowel syndrome: health status and use of health care services, Br J Gen Pract, 49, 787
  33. A Icks, 2002, Prevalence of functional bowel disorders and related health care seeking: a population-based study, Z Gastroenterol, 40, 177, 10.1055/s-2002-22324 · DOI
  34. X Badia, 2002, Burden of illness in irritable bowel syndrome comparing Rome I and Rome II criteria, Pharmacoeconomics, 20, 749, 10.2165/00019053-200220110-00004 · DOI
  35. S L Halder, 2007, Natural history of functional gastrointestinal disorders: a 12-year longitudinal population-based study, Gastroenterology, 133, 799, 10.1053/j.gastro.2007.06.010 · DOI
  36. W Hauser, 2019, The Prevalence, Comorbidity, Management and Costs of Irritable Bowel Syndrome, Dtsch Arztebl Int, 116, 463
  37. E B Andrews, 2005, Prevalence and demographics of irritable bowel syndrome: results from a large web-based survey, Aliment Pharmacol Ther, 22, 935, 10.1111/j.1365-2036.2005.02671.x · DOI
  38. A Minocha, 2006, Prevalence, sociodemography, and quality of life of older versus younger patients with irritable bowel syndrome: a population-based study, Dig Dis Sci, 51, 446, 10.1007/s10620-006-3153-8 · DOI
  39. H Kumano, 2004, Comorbidity of irritable bowel syndrome, panic disorder, and agoraphobia in a Japanese representative sample, Am J Gastroenterol, 99, 370, 10.1111/j.1572-0241.2004.04048.x · DOI
  40. M Kanazawa, 2008, Contributions of pain sensitivity and colonic motility to IBS symptom severity and predominant bowel habits, Am J Gastroenterol, 103, 2550, 10.1111/j.1572-0241.2008.02066.x · DOI
  41. J M Sabate, 2008, Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome, Aliment Pharmacol Ther, 28, 484, 10.1111/j.1365-2036.2008.03759.x · DOI
  42. W E Whitehead, 2006, Reports of “satisfactory relief“ by IBS patients receiving usual medical care are confounded by baseline symptom severity and do not accurately reflect symptom improvement, Am J Gastroenterol, 101, 1057, 10.1111/j.1572-0241.2006.00535.x · DOI · Paper page
  43. B D Bray, 2006, Symptom interpretation and quality of life in patients with irritable bowel syndrome, Br J Gen Pract, 56, 122
  44. D A Drossman, 1995, Functional bowel disorders. A multicenter comparison of health status and development of illness severity index, Dig Dis Sci, 40, 986
  45. A D Sperber, 2000, Use of the Functional Bowel Disorder Severity Index (FBDSI) in a study of patients with the irritable bowel syndrome and fibromyalgia, Am J Gastroenterol, 95, 995, 10.1111/j.1572-0241.2000.01977.x · DOI · Paper page
  46. J Svedlund, 1988, GSRS – a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease, Dig Dis Sci, 33, 129, 10.1007/BF01535722 · DOI
  47. P Karling, 2007, No difference in symptoms of irritable bowel syndrome between healthy subjects and patients with recurrent depression in remission, Neurogastroenterol Motil, 19, 896, 10.1111/j.1365-2982.2007.00967.x · DOI
  48. M Bengtsson, 2007, Development and psychometric testing of the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS), BMC Gastroenterol, 7, 16, 10.1186/1471-230X-7-16 · DOI
  49. I Posserud, 2007, Altered rectal perception in irritable bowel syndrome is associated with symptom severity, Gastroenterology, 133, 1113, 10.1053/j.gastro.2007.07.024 · DOI · Paper page
  50. B Spiegel, 2008, Predictors of patient-assessed illness severity in irritable bowel syndrome, Am J Gastroenterol, 103, 2536, 10.1111/j.1572-0241.2008.01997.x · DOI
  51. B A Hahn, 1997, Patient-perceived severity of irritable bowel syndrome in relation to symptoms, health resource utilization and quality of life, Aliment Pharmacol Ther, 11, 553, 10.1046/j.1365-2036.1997.00160.x · DOI
  52. A Lembo, 2005, Irritable bowel syndrome: toward an understanding of severity, Clin Gastroenterol Hepatol, 3, 717, 10.1016/S1542-3565(05)00157-6 · DOI
  53. M Camilleri, 2007, Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints, Clin Gastroenterol Hepatol, 5, 534, 10.1016/j.cgh.2007.03.004 · DOI
  54. W E Whitehead, 1996, Impact of irritable bowel syndrome on quality of life, Dig Dis Sci, 41, 2248, 10.1007/BF02071408 · DOI · Paper page
  55. C Brun-Strang, 2007, Irritable bowel syndrome in France: quality of life, medical management, and costs: the Encoli study, Eur J Gastroenterol Hepatol, 19, 1097, 10.1097/MEG.0b013e3282f1621b · DOI
  56. B B Dean, 2005, Impairment in work productivity and health-related quality of life in patients with IBS, Am J Manag Care, 11, S17
  57. L Frank, 2002, Health-related quality of life associated with irritable bowel syndrome: comparison with other chronic diseases, Clin Ther, 24, 675, 10.1016/S0149-2918(02)85143-8 · DOI
  58. S L Halder, 2004, Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study, Aliment Pharmacol Ther, 19, 233, 10.1111/j.0269-2813.2004.01807.x · DOI · Paper page
  59. F Creed, 2001, Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome, Ann Intern Med, 134, 860, 10.7326/0003-4819-134-9_Part_2-200105011-00010 · DOI
  60. B A Hahn, 1997, Evaluation of a new quality of life questionnaire for patients with irritable bowel syndrome, Aliment Pharmacol Ther, 11, 547, 10.1046/j.1365-2036.1997.00168.x · DOI
  61. M R Borgaonkar, 2000, Quality of life measurement in gastrointestinal and liver disorders, Gut, 47, 444, 10.1136/gut.47.3.444 · DOI
  62. C A McHorney, 1994, The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups, Med Care, 32, 40, 10.1097/00005650-199401000-00004 · DOI · Paper page
  63. J E Ware Jr, 1992, The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection, Med Care, 30, 473, 10.1097/00005650-199206000-00002 · DOI · Paper page
  64. J M Lackner, 2014, Fear of GI symptoms has an important impact on quality of life in patients with moderate-to-severe IBS, Am J Gastroenterol, 109, 1815, 10.1038/ajg.2014.241 · DOI
  65. J M Lackner, 2014, The impact of physical complaints, social environment, and psychological functioning on IBS patients’ health perceptions: looking beyond GI symptom severity, Am J Gastroenterol, 109, 224, 10.1038/ajg.2013.410 · DOI
  66. V L Michalsen, 2015, Predictors of health-related quality of life in patients with irritable bowel syndrome. A cross-sectional study in Norway, Health Qual Life Outcomes, 13, 113, 10.1186/s12955-015-0311-8 · DOI
  67. S Blagden, 2015, A Comparative Study of Quality of Life in Persons With Irritable Bowel Syndrome and Inflammatory Bowel Disease, Gastroenterol Nurs, 38, 268, 10.1097/SGA.0000000000000124 · DOI
  68. J L Liss, 1973, The irritable colon syndrome and psychiatric illness, Dis Nerv Syst, 34, 151
  69. S J Young, 1976, Psychiatric illness and the irritable bowel syndrome. Practical implications for the primary physician, Gastroenterology, 70, 162, 10.1016/S0016-5085(76)80002-9 · DOI · Paper page
  70. R B Lydiard, 1993, Prevalence of psychiatric disorders in patients with irritable bowel syndrome, Psychosomatics, 34, 229, 10.1016/S0033-3182(93)71884-8 · DOI · Paper page
  71. E A Walker, 1995, Psychiatric diagnoses, sexual and physical victimization, and disability in patients with irritable bowel syndrome or inflammatory bowel disease, Psychol Med, 25, 1259, 10.1017/S0033291700033225 · DOI
  72. C L Woodman, 1998, The relationship between irritable bowel syndrome and psychiatric illness. A family study, Psychosomatics, 39, 45, 10.1016/S0033-3182(98)71380-5 · DOI
  73. A R Miller, 2001, The association of irritable bowel syndrome and somatization disorder, Ann Clin Psychiatry, 13, 25, 10.3109/10401230109147126 · DOI · Paper page
  74. C S North, 1996, Gastrointestinal symptoms and psychiatric disorders in the general population. Findings from NIMH Epidemiologic Catchment Area Project, Dig Dis Sci, 41, 633, 10.1007/BF02213117 · DOI
  75. L A Aaron, 2001, A review of the evidence for overlap among unexplained clinical conditions, Ann Intern Med, 134, 868, 10.7326/0003-4819-134-9_Part_2-200105011-00011 · DOI · Paper page
  76. R A Kanaan, 2007, The association or otherwise of the functional somatic syndromes, Psychosom Med, 69, 855, 10.1097/PSY.0b013e31815b001a · DOI
  77. M D Fossey, 1990, Anxiety and the gastrointestinal system, Psychiatr Med, 8, 175
  78. E A Walker, 1990, Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease, Am J Psychiatry, 147, 1656, 10.1176/ajp.147.12.1656 · DOI
  79. C Irwin, 1996, Comorbidity of posttraumatic stress disorder and irritable bowel syndrome, J Clin Psychiatry, 57, 576, 10.4088/JCP.v57n1204 · DOI
  80. R B Lydiard, 2001, Irritable bowel syndrome, anxiety, and depression: what are the links?, J Clin Psychiatry, 62, 38
  81. E A Walker, 1991, The prevalence of chronic pelvic pain and irritable bowel syndrome in two university clinics, J Psychosom Obstet Gynaecol, 12, S65, 10.1080/0167482X.1991.11742721 · DOI · Paper page
  82. R G Maunder, 1998, Panic disorder associated with gastrointestinal disease: review and hypotheses, J Psychosom Res, 44, 91, 10.1016/S0022-3999(97)00133-5 · DOI
  83. R Noyes Jr, 1990, Reduction of gastrointestinal symptoms following treatment for panic disorder, Psychosomatics, 31, 75, 10.1016/S0033-3182(90)72220-7 · DOI
  84. D S Kaplan, 1996, The relationship of irritable bowel syndrome (IBS) and panic disorder, Ann Clin Psychiatry, 8, 81, 10.3109/10401239609148805 · DOI
  85. P P Roy-Byrne, 2008, Anxiety disorders and comorbid medical illness, Gen Hosp Psychiatry, 30, 208, 10.1016/j.genhosppsych.2007.12.006 · DOI · Paper page
  86. D F Gros, 2009, Frequency and severity of the symptoms of irritable bowel syndrome across the anxiety disorders and depression, J Anxiety Disord, 23, 290, 10.1016/j.janxdis.2008.08.004 · DOI · Paper page
  87. H Cohen, 2006, Post-traumatic stress disorder and other co-morbidities in a sample population of patients with irritable bowel syndrome, Eur J Intern Med, 17, 567, 10.1016/j.ejim.2006.07.011 · DOI
  88. L S Savas, 2009, Irritable bowel syndrome and dyspepsia among women veterans: prevalence and association with psychological distress, Aliment Pharmacol Ther, 29, 115, 10.1111/j.1365-2036.2008.03847.x · DOI
  89. E A Mayer, 2001, Depression, anxiety, and the gastrointestinal system, J Clin Psychiatry, 62, 28
  90. S J Perkins, 2005, Eating disorders and irritable bowel syndrome: is there a link?, J Psychosom Res, 59, 57, 10.1016/j.jpsychores.2004.04.375 · DOI
  91. C Boyd, 2005, Psychological features are important predictors of functional gastrointestinal disorders in patients with eating disorders, Scand J Gastroenterol, 40, 929, 10.1080/00365520510015836 · DOI · Paper page
  92. D Nellesen, 2013, Comorbidities in patients with irritable bowel syndrome with constipation or chronic idiopathic constipation: a review of the literature from the past decade, Postgrad Med, 125, 40, 10.3810/pgm.2013.03.2640 · DOI
  93. P Enck, 2016, Irritable bowel syndrome, Nat Rev Dis Primers, 2, 16014, 10.1038/nrdp.2016.14 · DOI
  94. M Camilleri, 2017, Biomarkers as a diagnostic tool for irritable bowel syndrome: where are we?, Expert Rev Gastroenterol Hepatol, 11, 303, 10.1080/17474124.2017.1288096 · DOI
  95. M Scheemann, 2017, Reizdarm und Reizmagen – Pathophysiologie und Biomarker, Der Gastroenterologe, 12, 114, 10.1007/s11377-017-0143-7 · DOI
  96. M Camilleri, 2014, Validating biomarkers of treatable mechanisms in irritable bowel syndrome, Neurogastroenterol Motil, 26, 1677, 10.1111/nmo.12421 · DOI
  97. M Camilleri, 2008, Prospective study of motor, sensory, psychologic, and autonomic functions in patients with irritable bowel syndrome, Clin Gastroenterol Hepatol, 6, 772, 10.1016/j.cgh.2008.02.060 · DOI
  98. N Manabe, Lower functional gastrointestinal disorders: evidence of abnormal colonic transit in a 287 patient cohort, Neurogastroenterol Motil, 22, 293-e282
  99. C Ng, 2005, Attenuation of the colorectal tonic reflex in female patients with irritable bowel syndrome, Am J Physiol Gastrointest Liver Physiol, 289, G489, 10.1152/ajpgi.00527.2004 · DOI
  100. S Fukudo, 2002, Exaggerated motility of the descending colon with repetitive distention of the sigmoid colon in patients with irritable bowel syndrome, J Gastroenterol, 37, 145, 10.1007/BF03326434 · DOI
  101. P P van der Veek, 2007, Recto-colonic reflex is impaired in patients with irritable bowel syndrome, Neurogastroenterol Motil, 19, 653, 10.1111/j.1365-2982.2007.00921.x · DOI
  102. T Lembo, 1997, Sigmoid afferent mechanisms in patients with irritable bowel syndrome, Dig Dis Sci, 42, 1112, 10.1023/A:1018817132213 · DOI
  103. J Serra, 2010, Impaired intestinal gas propulsion in manometrically proven dysmotility and in irritable bowel syndrome, Neurogastroenterol Motil, 22, 401, 10.1111/j.1365-2982.2009.01447.x · DOI
  104. C Peleman, 2017, Colonic Transit and Bile Acid Synthesis or Excretion in Patients With Irritable Bowel Syndrome-Diarrhea Without Bile Acid Malabsorption, Clin Gastroenterol Hepatol, 15, 720, 10.1016/j.cgh.2016.11.012 · DOI
  105. P Vijayvargiya, 2018, Bile Acid Deficiency in a Subgroup of Patients With Irritable Bowel Syndrome With Constipation Based on Biomarkers in Serum and Fecal Samples, Clin Gastroenterol Hepatol, 16, 522, 10.1016/j.cgh.2017.06.039 · DOI
  106. C Martinez, 2012, Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome, Gut Liver, 6, 305, 10.5009/gnl.2012.6.3.305 · DOI
  107. A M Gonzalez-Castro, 2017, Mucosal pathobiology and molecular signature of epithelial barrier dysfunction in the small intestine in irritable bowel syndrome, J Gastroenterol Hepatol, 32, 53, 10.1111/jgh.13417 · DOI
  108. M H Larsson, 2007, Elevated motility-related transmucosal potential difference in the upper small intestine in the irritable bowel syndrome, Neurogastroenterol Motil, 19, 812, 10.1111/j.1365-2982.2007.00941.x · DOI
  109. J E Medland, 2016, Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses, Neurogastroenterol Motil, 28, 1317, 10.1111/nmo.12828 · DOI
  110. L A Blackshaw, 2007, Sensory transmission in the gastrointestinal tract, Neurogastroenterol Motil, 19, 1, 10.1111/j.1365-2982.2006.00871.x · DOI
  111. H Mertz, 1995, Altered rectal perception is a biological marker of patients with irritable bowel syndrome, Gastroenterology, 109, 40, 10.1016/0016-5085(95)90267-8 · DOI · Paper page
  112. C Ng, 2006, Distension technique influences the relationship between colonic and rectal hypersensitivity in irritable bowel syndrome, Neurogastroenterol Motil, 18, 206, 10.1111/j.1365-2982.2005.00746.x · DOI
  113. J Scanzi, 2016, Colonic overexpression of the T-type calcium channel Cav 3.2 in a mouse model of visceral hypersensitivity and in irritable bowel syndrome patients, Neurogastroenterol Motil, 28, 1632, 10.1111/nmo.12860 · DOI
  114. J Munakata, 1997, Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome, Gastroenterology, 112, 55, 10.1016/S0016-5085(97)70219-1 · DOI
  115. J Serra, 1995, Perception and reflex responses to intestinal distention in humans are modified by simultaneous or previous stimulation, Gastroenterology, 109, 1742, 10.1016/0016-5085(95)90739-4 · DOI
  116. S Gonlachanvit, 2009, Effects of chili on postprandial gastrointestinal symptoms in diarrhoea predominant irritable bowel syndrome: evidence for capsaicin-sensitive visceral nociception hypersensitivity, Neurogastroenterol Motil, 21, 23, 10.1111/j.1365-2982.2008.01167.x · DOI
  117. S J van Wanrooij, 2014, Sensitivity testing in irritable bowel syndrome with rectal capsaicin stimulations: role of TRPV1 upregulation and sensitization in visceral hypersensitivity?, Am J Gastroenterol, 109, 99, 10.1038/ajg.2013.371 · DOI
  118. P A Hughes, 2013, Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes, Gut, 62, 1456, 10.1136/gutjnl-2011-301856 · DOI
  119. R Spiller, 2012, An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome, J Neurogastroenterol Motil, 18, 258, 10.5056/jnm.2012.18.3.258 · DOI
  120. S Gupta, 2016, Infectious disease: Something in the water, Nature, 533, S114, 10.1038/533S114a · DOI
  121. S M Collins, 2012, Postinfectious Chronic Gut Dysfunction: From Bench to Bedside, The American Journal of Gastroenterology Supplements, 1, 2, 10.1038/ajgsup.2012.2 · DOI
  122. M Schemann, 2013, Functions and imaging of mast cell and neural axis of the gut, Gastroenterology, 144, 698, 10.1053/j.gastro.2013.01.040 · DOI
  123. B L Pike, 2015, Immunological Biomarkers in Postinfectious Irritable Bowel Syndrome, J Travel Med, 22, 242, 10.1111/jtm.12218 · DOI
  124. T Liebregts, 2007, Immune activation in patients with irritable bowel syndrome, Gastroenterology, 132, 913, 10.1053/j.gastro.2007.01.046 · DOI · Paper page
  125. J D Wood, 2012, Anti-enteric neuronal antibodies and the irritable bowel syndrome, J Neurogastroenterol Motil, 18, 78, 10.5056/jnm.2012.18.1.78 · DOI
  126. T K Klooker, 2010, The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome, Gut, 59, 1213, 10.1136/gut.2010.213108 · DOI
  127. O S Palsson, 2004, Elevated vasoactive intestinal peptide concentrations in patients with irritable bowel syndrome, Dig Dis Sci, 49, 1236, 10.1023/B:DDAS.0000037818.64577.ef · DOI
  128. G Dothel, 2015, Nerve fiber outgrowth is increased in the intestinal mucosa of patients with irritable bowel syndrome, Gastroenterology, 148, 1002, 10.1053/j.gastro.2015.01.042 · DOI
  129. X J Xu, 2017, Increased expression of nerve growth factor correlates with visceral hypersensitivity and impaired gut barrier function in diarrhoea-predominant irritable bowel syndrome: a preliminary explorative study, Aliment Pharmacol Ther, 45, 100, 10.1111/apt.13848 · DOI
  130. S Berdun, 2015, Effects of nerve growth factor antagonist K252a on peritoneal mast cell degranulation: implications for rat postoperative ileus, Am J Physiol Gastrointest Liver Physiol, 309, G801, 10.1152/ajpgi.00152.2015 · DOI
  131. M P Guarino, 2017, Supernatants of irritable bowel syndrome mucosal biopsies impair human colonic smooth muscle contractility, Neurogastroenterol Motil, 29, 10.1111/nmo.12928 · DOI
  132. S Buhner, 2009, Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome, Gastroenterology, 137, 1425, 10.1053/j.gastro.2009.07.005 · DOI · Paper page
  133. G Barbara, 2007, Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome, Gastroenterology, 132, 26, 10.1053/j.gastro.2006.11.039 · DOI · Paper page
  134. S Buhner, 2012, Submucous rather than myenteric neurons are activated by mucosal biopsy supernatants from irritable bowel syndrome patients, Neurogastroenterol Motil, 24, 1134-e1572, 10.1111/nmo.12011 · DOI
  135. S Buhner, 2014, Neuronal activation by mucosal biopsy supernatants from irritable bowel syndrome patients is linked to visceral sensitivity, Exp Physiol, 99, 1299, 10.1113/expphysiol.2014.080036 · DOI
  136. D Ostertag, 2015, Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFalpha, and Tryptase (IBS-Cocktail), Front Neurosci, 9, 465, 10.3389/fnins.2015.00465 · DOI
  137. M El-Salhy, 2017, Abnormalities in ileal stem, neurogenin 3, and enteroendocrine cells in patients with irritable bowel syndrome, BMC Gastroenterol, 17, 90, 10.1186/s12876-017-0643-4 · DOI
  138. M El-Salhy, 2015, Densities of rectal peptide YY and somatostatin cells as biomarkers for the diagnosis of irritable bowel syndrome, Peptides, 67, 12, 10.1016/j.peptides.2015.02.008 · DOI
  139. M El-Salhy, 2015, Recent advances in the diagnosis of irritable bowel syndrome, Expert Rev Gastroenterol Hepatol, 9, 1161, 10.1586/17474124.2015.1067138 · DOI
  140. M El-Salhy, 2012, Low densities of serotonin and peptide YY cells in the colon of patients with irritable bowel syndrome, Dig Dis Sci, 57, 873, 10.1007/s10620-011-1948-8 · DOI
  141. R Spiller, 2008, Serotonin and GI clinical disorders, Neuropharmacology, 55, 1072, 10.1016/j.neuropharm.2008.07.016 · DOI
  142. M Grover, 2014, On the fiftieth anniversary. Postinfectious irritable bowel syndrome: mechanisms related to pathogens, Neurogastroenterol Motil, 26, 156, 10.1111/nmo.12304 · DOI · Paper page
  143. T Mazzawi, 2017, Changes in duodenal enteroendocrine cells in patients with irritable bowel syndrome following dietary guidance, Exp Biol Med (Maywood), 242, 1355, 10.1177/1535370217699537 · DOI
  144. J M Yano, 2015, Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis, Cell, 161, 264, 10.1016/j.cell.2015.02.047 · DOI · Paper page
  145. S Kumar, 2012, Serotonin transporter gene (SLC6A4) polymorphism in patients with irritable bowel syndrome and healthy controls, J Gastrointestin Liver Dis, 21, 31
  146. C Stasi, 2017, Neuroendocrine Dysregulation in Irritable Bowel Syndrome Patients: A Pilot Study, J Neurogastroenterol Motil, 23, 428, 10.5056/jnm16155 · DOI
  147. M D Coates, 2004, Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome, Gastroenterology, 126, 1657, 10.1053/j.gastro.2004.03.013 · DOI
  148. D Keszthelyi, 2013, Decreased levels of kynurenic acid in the intestinal mucosa of IBS patients: relation to serotonin and psychological state, J Psychosom Res, 74, 501, 10.1016/j.jpsychores.2013.01.008 · DOI
  149. D Keszthelyi, 2014, Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome, Aliment Pharmacol Ther, 40, 392, 10.1111/apt.12842 · DOI
  150. D Keszthelyi, 2015, Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study, Neurogastroenterol Motil, 27, 1127, 10.1111/nmo.12600 · DOI
  151. A Y Thijssen, 2016, Alterations in serotonin metabolism in the irritable bowel syndrome, Aliment Pharmacol Ther, 43, 272, 10.1111/apt.13459 · DOI
  152. K Mueller, 2011, Activity of protease-activated receptors in the human submucous plexus, Gastroenterology, 141, 2088, 10.1053/j.gastro.2011.08.034 · DOI
  153. A P Kerckhoffs, 2008, Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients, Neurogastroenterol Motil, 20, 900, 10.1111/j.1365-2982.2008.01100.x · DOI
  154. C Rolland-Fourcade, 2017, Epithelial expression and function of trypsin-3 in irritable bowel syndrome, Gut, 66, 1767, 10.1136/gutjnl-2016-312094 · DOI · Paper page
  155. S Buhner, 2018, Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients, PLoS One, 13, e0193943, 10.1371/journal.pone.0193943 · DOI
  156. C Desormeaux, 2018, Protease-activated receptor 1 is implicated in irritable bowel syndrome mediators-induced signaling to thoracic human sensory neurons, Pain, 159, 1257, 10.1097/j.pain.0000000000001208 · DOI
  157. P G Farup, 2016, Faecal short-chain fatty acids – a diagnostic biomarker for irritable bowel syndrome?, BMC Gastroenterol, 16, 51, 10.1186/s12876-016-0446-z · DOI
  158. E A Mayer, 2015, Imaging brain mechanisms in chronic visceral pain, Pain, 156, S50, 10.1097/j.pain.0000000000000106 · DOI
  159. H Mertz, 2000, Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention, Gastroenterology, 118, 842, 10.1016/S0016-5085(00)70170-3 · DOI · Paper page
  160. A Lawal, 2006, Novel evidence for hypersensitivity of visceral sensory neural circuitry in irritable bowel syndrome patients, Gastroenterology, 130, 26, 10.1053/j.gastro.2005.10.020 · DOI
  161. B D Naliboff, 2003, Sex-related differences in IBS patients: central processing of visceral stimuli, Gastroenterology, 124, 1738, 10.1016/S0016-5085(03)00400-1 · DOI
  162. T Tanaka, 2008, Characterization of autonomic dysfunction in patients with irritable bowel syndrome using fingertip blood flow, Neurogastroenterol Motil, 20, 498, 10.1111/j.1365-2982.2007.01039.x · DOI
  163. R Spaziani, 2008, Vagal dysfunction in irritable bowel syndrome assessed by rectal distension and baroreceptor sensitivity, Neurogastroenterol Motil, 20, 336, 10.1111/j.1365-2982.2007.01042.x · DOI
  164. S Spetalen, 2008, Autonomic function at rest and in response to emotional and rectal stimuli in women with irritable bowel syndrome, Dig Dis Sci, 53, 1652, 10.1007/s10620-007-0066-0 · DOI
  165. M Mazur, 2007, Dysfunction of the autonomic nervous system activity is responsible for gastric myoelectric disturbances in the irritable bowel syndrome patients, J Physiol Pharmacol, 58, 131
  166. M Heitkemper, 1996, Increased urine catecholamines and cortisol in women with irritable bowel syndrome, Am J Gastroenterol, 91, 906
  167. M Heitkemper, 2001, Autonomic nervous system function in women with irritable bowel syndrome, Dig Dis Sci, 46, 1276, 10.1023/A:1010671514618 · DOI · Paper page
  168. A Polster, 2018, Heart rate variability characteristics of patients with irritable bowel syndrome and associations with symptoms, Neurogastroenterol Motil, 30, e13320, 10.1111/nmo.13320 · DOI
  169. Y Tanaka, 2018, Increased Postprandial Colonic Motility and Autonomic Nervous System Activity in Patients With Irritable Bowel Syndrome: A Prospective Study, J Neurogastroenterol Motil, 24, 87, 10.5056/jnm16216 · DOI
  170. A Mulak, 2014, Sex hormones in the modulation of irritable bowel syndrome, World J Gastroenterol, 20, 2433, 10.3748/wjg.v20.i10.2433 · DOI
  171. M Meleine, 2014, Gender-related differences in irritable bowel syndrome: potential mechanisms of sex hormones, World J Gastroenterol, 20, 6725, 10.3748/wjg.v20.i22.6725 · DOI
  172. C Kiank, 2010, Stress-related modulation of inflammation in experimental models of bowel disease and post-infectious irritable bowel syndrome: role of corticotropin-releasing factor receptors, Brain Behav Immun, 24, 41, 10.1016/j.bbi.2009.08.006 · DOI
  173. M Chatoo, 2018, Involvement of Corticotropin-Releasing Factor and Receptors in Immune Cells in Irritable Bowel Syndrome, Front Endocrinol (Lausanne), 9, 21, 10.3389/fendo.2018.00021 · DOI
  174. C Markert, 2016, Endocrine dysregulation in women with irritable bowel syndrome according to Rome II criteria, J Behav Med, 39, 519, 10.1007/s10865-016-9718-x · DOI
  175. K A Suarez-Hitz, 2012, Altered psychobiological responsiveness in women with irritable bowel syndrome, Psychosom Med, 74, 221, 10.1097/PSY.0b013e318244fb82 · DOI
  176. Y A Saito, 2011, The role of genetics in IBS, Gastroenterol Clin North Am, 40, 45, 10.1016/j.gtc.2010.12.011 · DOI
  177. C Wohlfarth, 2017, miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome, Sci Rep, 7, 14680, 10.1038/s41598-017-13982-0 · DOI
  178. M Henstrom, 2017, TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M, Gut, 66, 1725, 10.1136/gutjnl-2016-313346 · DOI
  179. M Henstrom, 2018, Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome, Gut, 67, 263, 10.1136/gutjnl-2016-312456 · DOI · Paper page
  180. E G Holliday, 2014, Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome, Am J Gastroenterol, 109, 770, 10.1038/ajg.2014.56 · DOI
  181. W E Ek, 2015, Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts, Gut, 64, 1774, 10.1136/gutjnl-2014-307997 · DOI
  182. F Bonfiglio, 2018, A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome, Neurogastroenterol Motil, 30, e13358, 10.1111/nmo.13358 · DOI
  183. T G Dinan, 2010, IBS: An epigenetic perspective, Nat Rev Gastroenterol Hepatol, 7, 465
  184. S Mahurkar, 2016, Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome, Neurogastroenterol Motil, 28, 410, 10.1111/nmo.12741 · DOI
  185. X J Liao, 2016, MicroRNA-24 inhibits serotonin reuptake transporter expression and aggravates irritable bowel syndrome, Biochem Biophys Res Commun, 469, 288, 10.1016/j.bbrc.2015.11.102 · DOI
  186. C Codling, 2010, A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome, Dig Dis Sci, 55, 392, 10.1007/s10620-009-0934-x · DOI · Paper page
  187. L Krogius-Kurikka, 2009, Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers, BMC Gastroenterol, 9, 95, 10.1186/1471-230X-9-95 · DOI
  188. A P Kerckhoffs, 2009, Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients, World J Gastroenterol, 15, 2887, 10.3748/wjg.15.2887 · DOI · Paper page
  189. C Chassard, 2012, Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome, Aliment Pharmacol Ther, 35, 828, 10.1111/j.1365-2036.2012.05007.x · DOI
  190. J Jalanka-Tuovinen, 2014, Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome, Gut, 63, 1737, 10.1136/gutjnl-2013-305994 · DOI · Paper page
  191. N Maharshak, 2018, Fecal and Mucosa-Associated Intestinal Microbiota in Patients with Diarrhea-Predominant Irritable Bowel Syndrome, Dig Dis Sci, 63, 1890, 10.1007/s10620-018-5086-4 · DOI
  192. A A Villarreal, 2012, Use of broad-spectrum antibiotics and the development of irritable bowel syndrome, WMJ, 111, 17
  193. J Tap, 2017, Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome, Gastroenterology, 152, 111, 10.1053/j.gastro.2016.09.049 · DOI · Paper page
  194. S MP Bennet, 2018, Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs, Gut, 67, 872, 10.1136/gutjnl-2016-313128 · DOI · Paper page
  195. K A Gwee, 1996, Psychometric scores and persistence of irritable bowel after infectious diarrhoea, Lancet, 347, 150, 10.1016/S0140-6736(96)90341-4 · DOI
  196. A Ruigomez, 1999, One-year follow-up of newly diagnosed irritable bowel syndrome patients, Aliment Pharmacol Ther, 13, 1097, 10.1046/j.1365-2036.1999.00576.x · DOI
  197. K R Neal, 2002, Prognosis in post-infective irritable bowel syndrome: a six year follow up study, Gut, 51, 410, 10.1136/gut.51.3.410 · DOI
  198. W E Whitehead, 1990, Tolerance for rectosigmoid distention in irritable bowel syndrome, Gastroenterology, 98, 1187, 10.1016/0016-5085(90)90332-U · DOI · Paper page
  199. B D Naliboff, 1997, Evidence for two distinct perceptual alterations in irritable bowel syndrome, Gut, 41, 505, 10.1136/gut.41.4.505 · DOI
  200. S D Dorn, 2007, Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity, Gut, 56, 1202, 10.1136/gut.2006.117390 · DOI

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Metadata

Authors
Layer, P., Andresen, V., Allescher, H., Bischoff, S. C., Claßen, M., Elsenbruch, S., Freitag, M., Frieling, T., Gebhard, M., Goebel-Stengel, M., Häuser, W., Holtmann, G., Keller, J., Kreis, M. E., Kruis, W., Langhorst, J., Jansen, P. L., Madisch, A., Mönnikes, H., Müller-Lissner, S., Niesler, B., Pehl, C., Pohl, D., Raithel, M., Röhrig-Herzog, G., Schemann, M., Schmiedel, S., Schwille-Kiuntke, J., Storr, M., Preiß, J. C., Andus, T., Buderus, S., Ehlert, U., Engel, M., Enninger, A., Fischbach, W., Gillessen, A., Gschossmann, J., Gundling, F., Haag, S., Helwig, U., Hollerbach, S., Karaus, M., Katschinski, M., Krammer, H., Kuhlbusch-Zicklam, R., Matthes, H., Menge, D., Miehlke, S., Posovszky, M. C., Schaefert, R., Schmidt-Choudhury, A., Schwandner, O., Schweinlin, A., Seidl, H., Stengel, A., Tesarz, J., van der Voort, I., Voderholzer, W., von Boyen, G., von Schönfeld, J., Wedel, T., Collaborators:, mit:, I. Z., (DEGAM), D. G. F. A. U. F., (DGAKI), D. G. F. A. U. K. I., (DGAV), D. G. F. A. U. V., (DGEM), D. G. F. E., (DGG), D. G. F. G., (DGIM), D. G. F. I. M., (DGNHK), D. G. F. N., (DGP/BDP), D. G. F. P. U. B. D. P. E. V., (DGPM), D. G. F. P. M. U. Ä. P., (DGVM), D. G. F. V. U. V., Deutsche Schmerzgesellschaft e., V., Deutsches Kollegium für Psychosomatische Medizin (DKPM), D. G. F. T. U. I. G. (., (GPGE), G. F. P. G. U. E., (DGKJ), D. G. F. K. U. J., Swiss Society of Neurogastroenterology and Motility (SwissNGM), & (MAGDA), I. F. P. M. M.-D.-E.
Affiliations
  • Medizinische Klinik, Israelitisches Krankenhaus, Hamburg, Deutschland
  • Zentrum für Innere Medizin, Gastroent., Hepatologie u. Stoffwechsel, Klinikum Garmisch-Partenkirchen, Garmisch-Partenkirchen, Deutschland
  • Institut für Ernährungsmedizin, Universität Hohenheim, Stuttgart, Deutschland
  • Klinik für Kinder- und Jugendmedizin, Klinikum Links der Weser, Bremen, Deutschland
  • Klinik für Neurologie, Translational Pain Research Unit, Universitätsklinikum Essen, Essen, Deutschland
  • Abteilung Allgemeinmedizin Department für Versorgungsforschung, Universität Oldenburg, Oldenburg, Deutschland
  • Medizinische Klinik II, Helios Klinikum Krefeld, Krefeld, Deutschland
  • Gemeinschaftspraxis Pathologie-Hamburg, Hamburg, Deutschland
  • Innere Medizin II, Helios Klinik Rottweil, Rottweil, und Innere Medizin VI, Psychosomat. Medizin u. Psychotherapie, Universitätsklinikum Tübingen, Tübingen, Deutschland
  • Innere Medizin I mit Schwerpunkt Gastroenterologie, Klinikum Saarbrücken, Saarbrücken, Deutschland
  • Faculty of Medicine & Faculty of Health & Behavioural Sciences, Princess Alexandra Hospital, Brisbane, Australien
  • Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland
  • Pulheim, Deutschland
  • Klinik für Integrative Medizin und Naturheilkunde, Sozialstiftung Bamberg, Klinikum am Bruderwald, Bamberg, Deutschland
  • Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten, Berlin, Deutschland
  • Klinik für Gastroenterologie, interventionelle Endoskopie und Diabetologie, Klinikum Siloah, Klinikum Region Hannover, Hannover, Deutschland
  • Klinik für Innere Medizin, Martin-Luther-Krankenhaus, Berlin, Deutschland
  • Berlin, Deutschland
  • Abteilung Molekulare Humangenetik Institut für Humangenetik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland
  • Medizinische Klinik, Krankenhaus Vilsbiburg, Vilsbiburg, Deutschland
  • Klinik für Gastroenterologie und Hepatologie, Universitätsspital Zürich, Zürich, Schweiz
  • Medizinische Klinik II m.S. Gastroenterologie und Onkologie, Waldkrankenhaus St. Marien, Erlangen, Deutschland
  • Geriatrie, St. Marien-Hospital, Köln, Deutschland
  • Lehrstuhl für Humanbiologie, TU München, Deutschland
  • I. Medizinische Klinik und Poliklinik Gastroenterologie, Universitätsklinikum Hamburg-Eppendorf, Deutschland
  • Abteilung für Psychosomatische Medizin und Psychotherapie, Medizinische Universitätsklinik Tübingen, Tübingen, Deutschland
  • Zentrum für Endoskopie, Gesundheitszentrum Starnberger See, Starnberg, Deutschland
  • Klinik für Innere Medizin – Gastroenterologie, Diabetologie und Hepatologie, Vivantes Klinikum Neukölln, Berlin, Deutschland
Venue
Zeitschrift für Gastroenterologie
Publisher
Georg Thieme Verlag KG
Published
2021-12
Volume
59
Issue
12
Pages
1323-1415
ISSN
  • 0044-2771
  • 1439-7803
DOI
10.1055/a-1591-4794
Cited by
76
References
168
Language
de

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CoChat. (2026). Citation check: Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM)—Juni 2021—AWMF-Registriernummer: 021/016. https://app.cochat.ai/papers/10.1055/a-1591-4794
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Layer, P., Andresen, V., Allescher, H., Bischoff, S. C., Claßen, M., Elsenbruch, S., Freitag, M., Frieling, T., Gebhard, M., Goebel-Stengel, M., Häuser, W., Holtmann, G., Keller, J., Kreis, M. E., Kruis, W., Langhorst, J., Jansen, P. L., Madisch, A., Mönnikes, H., . . . (MAGDA), I. F. P. M. M.-D.-E. (2021). Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM)—Juni 2021—AWMF-Registriernummer: 021/016. Zeitschrift für Gastroenterologie. https://doi.org/10.1055/a-1591-4794

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