Cited by 113Endometriosis Research and TreatmentReproductive System and PregnancyReproductive Biology and Fertility

The DOI matches its Crossref record; 252 of the 252 references it cites were found in a registry or an index.

Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects

Lessey, Bruce, Lebovic, Dan, Taylor, Robert·2013·Seminars in Reproductive Medicine

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Abstract

The endometrium is ground zero when it comes to understanding how implantation occurs and how it might also fail, resulting in infertility or pregnancy loss. Many of the causes of diminished uterine receptivity are acquired during a woman's lifetime. Endometriosis, a major inflammatory disease affecting women, is also a leading cause of infertility and miscarriage. Once established, the inflammatory changes can, in some women, lead to progesterone resistance and downstream changes in endometrial gene expression. Much is now known about how inflammation translates to progesterone resistance and infertility, but much remains to be learned. In this review we provide an overview for understanding how the endometrium becomes dysfunctional, what biomarkers may hold promise for the diagnosis of endometriosis, and how progesterone resistance leads to infertility. Understanding the pathophysiology of this disease will likely lead to better treatment options.

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Endometriosis
Zondervan, K. T., Becker, C. M., Koga, K., Missmer, S. A., Taylor, R. N., & Viganò, P. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0008-5 · Cited by 1,257
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Self-citation
Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why
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Self-citation

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Authors: Lessey, B., Lebovic, D., & Taylor, R.
Affiliations: Prisma Health (US)
University of Wisconsin System (US)
Wake Forest University Health Sciences (US)
ORCID: Lessey, Bruce
Lebovic, Dan
Venue: Seminars in Reproductive Medicine
Publisher: Georg Thieme Verlag KG
Published: 2013-02-27
Volume: 31
Issue: 02
Pages: 109-124
ISSN: 1526-4564 (ISSN-L)
1526-8004
DOI: 10.1055/s-0032-1333476
OpenAlex: W1984413516
Cited by: 113
References: 252
Citations by year: 2026: 4 · 2025: 2 · 2024: 8 · 2023: 8 · 2022: 13 · 2021: 9 · 2020: 13 · 2019: 7 · 2018: 7 · 2017: 7 · 2016: 11 · 2015: 15 · 2014: 7 · 2013: 2
FWCI: 14.09
Type: journal article
Language: en
Open access: closed
Locations: Seminars in Reproductive Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD067721)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords: endometriosis, endometrium, implantation defects, endometrial receptivity, progesterone resistance, infertility, miscarriage, endometritis, endometrial gene expression, endometriosis diagnosis
MeSH terms: Animals, Endometriosis, Endometrium, Female, Humans, Infertility, Female, Embryo Implantation, Pregnancy, Pregnancy Maintenance, Progesterone, Biomarkers, Chemokines, Embryo Loss

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Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects

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