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Cited by 194Coffee research and impactsAlcohol Consumption and Health EffectsCoconut Research and Applications

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

The Effect on Serum Cholesterol Levels of Coffee Brewed by Filtering or Boiling

Bak, Annette A.A., Grobbee, Diederick E.·1989·New England Journal of Medicine
DOI 10.1056/nejm198911233212103
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Abstract

Previous reports have indicated that coffee consumption may increase serum cholesterol levels. We studied the effects of coffee prepared by two common brewing methods (filtering and boiling) on serum lipid levels in a 12-week randomized trial involving 107 young adult subjects with normal serum cholesterol levels. After a three-week run-in period during which they all consumed filtered coffee, the participants were randomly assigned to one of three groups receiving four to six cups of boiled coffee a day, four to six cups of filtered coffee a day, or no coffee, for a period of nine weeks. As compared with the change from base line in the filtered-coffee group, the serum total cholesterol level increased after the consumption of boiled coffee by 0.48 mmol per liter (95 percent confidence limits, 0.13 and 0.83), and the low-density lipoprotein cholesterol level increased by 0.39 mmol per liter (95 percent confidence limits, -0.04 and 0.82). There was no significant difference in the change in serum total or low-density lipoprotein cholesterol levels between the filtered-coffee group and the group that drank no coffee. The levels of high-density lipoprotein cholesterol and apolipoproteins were not affected by boiled or filtered coffee. We conclude that drinking filtered coffee does not affect serum lipid levels. The consumption of boiled coffee, however, has an effect on serum cholesterol levels amounting to a mean net increase of 10 percent of the base-line level after nine weeks.

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Crossref · 10.1056/nejm198911233212103

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Citations

Cites

Research works printed but not linked: 7

  1. Nichols, 1976, JAMA, 236, 1948, 10.1001/jama.1976.03270180024014 · DOI
  2. Kovar, 1983, N Engl J Med, 309, 1249
  3. Shekelle, 1983, N Engl J Med, 309, 1249
  4. Arab, 1983, N Engl J Med, 309, 1250
  5. Folsom, 1984, CVD Epidemiol Newsl, 35, 53
  6. Amesen, 1984, Br Med J, 288, 1960
  7. Grove, 1979, ClinChem, 25, 560

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Metadata

Authors
Bak, A. A. A., & Grobbee, D. E.
Affiliations
Erasmus MC (NL)
ORCID
Grobbee, Diederick E.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1989-11-23
Volume
321
Issue
21
Pages
1432-1437
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm198911233212103
OpenAlex
W2332265208
Cited by
194
References
38
Citations by year
2026: 2 · 2025: 4 · 2024: 5 · 2023: 4 · 2022: 1 · 2021: 2 · 2020: 5 · 2019: 5 · 2018: 6 · 2017: 5 · 2016: 4 · 2015: 4 · 2014: 3 · 2013: 5 · 2012: 1
FWCI
15.18
Type
journal article
Language
en
Open access
closed
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Coconut Research and Applications
Keywords
coffee, brewing technology, filtered coffee, boiled coffee, serum cholesterol, LDL cholesterol, serum lipids, HDL cholesterol, apolipoproteins, dietary fat intake
MeSH terms
Adult, Apolipoproteins, Cholesterol, Coffee, Cooking, Female, Filtration, Humans, Cholesterol, HDL, Cholesterol, LDL, Male, Random Allocation

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