Cited by 1,188Sex and Gender in HealthcareCoronary Interventions and DiagnosticsAcute Myocardial Infarction Research

Differences in the use of procedures between women and men hospitalized for coronary heart disease

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Ayanian, John Z., Epstein, Arnold M.·1991·New England Journal of Medicine

Abstract

BACKGROUND AND METHODS: Previous studies at individual hospitals have reported differences in the use of major diagnostic and therapeutic procedures for women and men with coronary heart disease. To assess whether these differences can be generalized, we performed retrospective analyses of coronary angiography and revascularization (coronary-artery bypass surgery or percutaneous transluminal coronary angioplasty) in women and men hospitalized for coronary heart disease in 1987, using abstract data on 49,623 discharges in Massachusetts and 33,159 discharges in Maryland. We used multiple logistic regression to estimate the adjusted odds of the use of a procedure, controlling for principal diagnosis, age, secondary diagnosis of congestive heart failure or diabetes mellitus, race, and insurance status. RESULTS: The adjusted odds of undergoing angiography were 28 percent and 15 percent higher for men than for women in Massachusetts and Maryland, respectively (95 percent confidence intervals for the odds ratios, 1.22 to 1.35 and 1.08 to 1.22). The respective adjusted odds of undergoing revascularization were 45 percent and 27 percent higher for men than for women (95 percent confidence intervals, 1.35 to 1.55 and 1.16 to 1.40). Because these differences could be related to differing thresholds for hospital admission, we performed a second analysis limited to patients with diagnosed acute myocardial infarction (11,865 discharges in Massachusetts and 6894 discharges in Maryland), a group in which all patients would be expected to receive hospital care. The male-to-female odds ratios in both states remained similar in magnitude and were statistically significant for angiography and revascularization. CONCLUSIONS: These findings demonstrate that women who are hospitalized for coronary heart disease undergo fewer major diagnostic and therapeutic procedures than men. These differences may represent appropriate levels of care for men and women, but it is also possible that they reflect underuse in women or overuse in men. Further study should assess the cause of these differences and their effect on patients' outcomes.

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Crossref · 10.1056/nejm199107253250401

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  • Considering as radically different certain situations that are, to some extent, similar in health for men and women can eventually produce inequities such as the fact that for the same coronary pathological condition, women do not receive the same health care or the same medical and surgical treatment.

    “Considering as radically different certain situations that are, to some extent, similar in health for men and women can eventually produce inequities such as the fact that for the same coronary pathological condition, women do not receive the same health care or the same medical and surgical treatment (Ayanian & Epstein, 1991; Canto et al., 2000; Melberg, Kindervaag, & R”

    From Health From a Gender Perspective (2017) · cites this paper as Ayanian & Epstein, 1991

  • When they have the same cardiopathological condition, women do not receive the same medical and surgical treatment; nor do they have the same probability of receiving the treatment that will potentially save their lives.

    “Not realizing that cardiovascular diseases are also the leading cause of mortality in women may produce effects like that noted by Ayanian and Epstein (1991), showing that when they have the same cardiopathological condition, women do not receive the same medical and surgical treatment; nor do they have the same probability of receiving the treatment that will potentially save their”

    From Health From a Gender Perspective (2017) · cites this paper as Ayanian & Epstein, 1991

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Authors
Ayanian, J. Z., & Epstein, A. M.
Affiliations
Brigham and Women's Hospital (US)
Venue
New England Journal of Medicine
Published
1991-07-25
Volume
325
Issue
4
Pages
221-225
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2331499127
Cited by
1,188
References
0
Citations by year
2026: 5 · 2025: 11 · 2024: 23 · 2023: 14 · 2022: 11 · 2021: 14 · 2020: 14 · 2019: 16 · 2018: 15 · 2017: 8 · 2016: 18 · 2015: 24 · 2014: 16 · 2013: 30 · 2012: 23
FWCI
77.07
Type
journal article
Language
en
Open access
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • DigitalGeorgetown (Georgetown University Library) (submittedVersion)
Funders
Agency for Healthcare Research and Quality (1 PO1 HS 06341)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
  • Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
Keywords
coronary artery disease, sex differences, coronary angiography, coronary revascularization, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty, acute myocardial infarction, underuse of care, women's health, hospital discharge data
MeSH terms
Adult, Aged, Aged, 80 and over, Angiography, Coronary Artery Bypass, Coronary Disease, Female, Hospitalization, Humans, Male, Maryland, Massachusetts, Middle Aged, Myocardial Infarction, Practice Patterns, Physicians', Prejudice, Retrospective Studies, Sex Factors, Models, Statistical, Odds Ratio, Women's Health, Coronary Angiography

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